Thue W. Schwartz

Thue W. Schwartz

Professor

Member of:

    ORCID: 0000-0002-0261-6904

    Publication year:
    All
    101 - 125 out of 258Page size: 25
    1. 2012
    2. Published

      An aromatic region to induce a switch between agonism and inverse agonism at the ghrelin receptor

      Els, S., Schild, E., Petersen, P. S., Kilian, T., Mokrosinski, J., Frimurer, Thomas Michael, Chollet, C., Schwartz, Thue W., Holst, Birgitte & Beck-Sickinger, A. G., 13 Sep 2012, In: Journal of Medicinal Chemistry. 55, 17, p. 7437-49 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      Modulation of constitutive activity and signaling bias of the ghrelin receptor by conformational constraint in the second extracellular loop

      Mokrosinski, J., Frimurer, Thomas Michael, Sivertsen, B., Schwartz, Thue W. & Holst, Birgitte, Sep 2012, In: Journal of Biological Chemistry. 287, p. 33488-33502 15 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      Effects of intravenous infusions of PYY3-36 and GLP-1, as monoinfusion and in combination, on ad libitum energy intake in healthy obese subjects

      Schmidt, J. B., Gregersen, N. T., Pedersen, S. D., Holst, Jens Juul, Schwartz, Thue W., Astrup, A. & Sjödin, Anders Mikael, 10 Aug 2012, In: Regulatory Peptides. 177, Supplement, p. S32 1 p.

      Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

    5. Published

      GPR119 as a fat sensor

      Hansen, Harald S., Rosenkilde, Mette, Holst, Jens Juul & Schwartz, Thue W., Jul 2012, In: Trends in Pharmacological Sciences. 33, 7, p. 374-81 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. 2011
    7. Published

      Structural biology: snapshot of a signalling complex.

      Schwartz, Thue W. & Sakmar, T., Sep 2011, In: Nature.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Ligand Modulation of the Epstein-Barr Virus-induced Seven-transmembrane Receptor EBI2: IDENTIFICATION OF A POTENT AND EFFICACIOUS INVERSE AGONIST

      Benned-Jensen, T., Smethurst, C., Holst, Peter Johannes, Page, K. R., Sauls, H., Sivertsen, B. B., Schwartz, Thue W., Blanchard, A., Jepras, R. & Rosenkilde, Mette, 19 Aug 2011, In: Journal of Biological Chemistry. 286, p. 29292-29302 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Deficiency of the GPR39 receptor is associated with obesity and altered adipocyte metabolism

      Petersen, P. S., Jin, C., Madsen, A. N., Rasmussen, M., Kuhre, Rune Ehrenreich, Egerod, Kristoffer Lihme, Nielsen, L. B., Schwartz, Thue W. & Holst, Birgitte, 22 Jul 2011, In: FASEB Journal. p. 3803-3814 12 p., 4.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Unique interaction pattern for a functionally biased ghrelin receptor agonist

      Sivertsen, B. B., Lang, M., Frimurer, T. M., Holliday, N. D., Bach, Anders, Els, S., Engelstoft, M. S., Petersen, P. S., Madsen, A. N., Schwartz, Thue W., Beck-Sickinger, A. G. & Holst, Birgitte, 10 Jun 2011, In: The Journal of Biological Chemistry. 286, 23, p. 20845-20860 16 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      KU bestemmer selv over sin forskning

      Wewer, Ulla M., Holst, Jens Juul, Schwartz, Thue W. & Quistorff, B., 2 Jun 2011, In: Universitetsavisen.

      Research output: Contribution to journal › Contribution to newspaper - Comment/debate › Communication

    12. Published

      Reversible switching of ultrastrong light-molecule coupling

      Schwartz, Thue W., Hutchison, J. A., Genet, C. & Ebbesen, T. W., 13 May 2011, In: Physical Review - Index. 106, p. 196405 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      G protein-coupled receptor modulation with pepducins: moving closer to the clinic

      Dimond, P., Carlson, K., Bouvier, M., Gerard, C., Xu, L., Covic, L., Agarwal, A., Ernst, O. P., Janz, J. M., Schwartz, Thue W., Gardella, T. J., Milligan, G., Kuliopulos, A., Sakmar, T. P. & Hunt III, S. W., May 2011, In: New York Academy of Sciences. Annals. 1226, p. 34-49 16 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      G protein-coupled receptor modulation with pepducins: moving closer to the clinic

      Dimond, P., Carlson, K., Bouvier, M., Gerard, C., Xu, L., Covic, L., Agarwal, A., Ernst, O. P., Janz, J. M., Schwartz, Thue W., Gardella, T. J., Milligan, G., Kuliopulos, A., Sakmar, T. P. & Hunt, S. W., 2011, In: Annals of the New York Academy of Sciences. 1226, p. 34-49 16 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      Long-acting lipidated analogue of human pancreatic polypeptide is slowly released into circulation

      Bellmann-Sickert, K., Elling, C. E., Madsen, A. N., Little, P. B., Lundgren, K., Gerlach, L., Bergmann, R., Holst, Birgitte, Schwartz, Thue W. & Beck-Sickinger, A. G., 2011, In: Journal of Medicinal Chemistry. 54, 8, p. 2658-67 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      ß-Cell Specific Overexpression of GPR39 Protects against Streptozotocin-Induced Hyperglycemia

      Egerod, Kristoffer Lihme, Jin, C., Petersen, P. S., Wierup, N., Sundler, F., Holst, Birgitte & Schwartz, Thue W., 2011, In: International Journal of Endocrinology. 2011, p. 401258

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. 2010
    18. Published

      A conserved aromatic lock for the tryptophan rotameric switch in TM-VI of seven-transmembrane receptors

      Holst, Birgitte, Nygaard, R., Hansen, L. V., Bach, Anders, Engelstoft, M. S., Petersen, P. S., Frimurer, T. M. & Schwartz, Thue W., 2010, In: Journal of Biological Chemistry. 285, 6, p. 3973-85 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      An enteroendocrine full package solution

      Schwartz, Thue W. & Holst, Birgitte, 2010, In: Cell Metabolism. 11, 6, p. 445-7 2 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      Conserved water-mediated hydrogen bond network between TM-I, -II, -VI, and -VII in 7TM receptor activation

      Nygaard, R., Hansen, L. V., Mokrosinski, J., Frimurer, T. M. & Schwartz, Thue W., 2010, In: Journal of Biological Chemistry. 285, 25, p. 19625-36 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      Family and population-based studies of variation within the ghrelin receptor locus in relation to measures of obesity

      Gjesing, A. P., Larsen, L. H., Torekov, S. S., Hainerová, I. A., Kapur, R., Johansen, A., Albrechtsen, A., Boj, S., Holst, B., Harper, A., Urhammer, S. A., Borch-Johnsen, K., Pisinger, C. H., Echwald, S. M., Eiberg, H. R. L., Astrup, A., Lebl, J., Ferrer, J., Schwartz, T. W., Hansen, T. & 1 others, Pedersen, Oluf Borbye, 2010, In: P L o S One. 5, 4, 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      MTNR1B G24E variant associates With BMI and fasting plasma glucose in the general population in studies of 22,142 Europeans

      Andersson, E. A., Holst, Birgitte, Sparsø, T., Grarup, Niels, Banasik, Karina, Holmkvist, J., Jørgensen, T., Borch-Johnsen, K., Egerod, Kristoffer Lihme, Lauritzen, T., Sørensen, Thorkild I.A., Bonnefond, A., Meyre, D., Froguel, P., Schwartz, Thue W., Pedersen, Oluf Borbye & Hansen, Torben, 2010, In: Diabetes. 59, 6, p. 1539-48 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Molecular basis for agonism in the BB3 receptor: an epitope located on the interface of transmembrane-III, -VI, and -VII

      Gbahou, F., Holst, Birgitte & Schwartz, Thue W., 2010, In: Journal of Pharmacology and Experimental Therapeutics. 333, 1, p. 51-9 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      Resequencing of 200 human exomes identifies an excess of low-frequency non-synonymous coding variants

      Li, Y., Vinckenbosch, N., Tian, G., Huerta-Sanchez, E., Jiang, T., Jiang, H., Albrechtsen, A., Andersen, G., Cao, H., Korneliussen, T. S., Grarup, N., Guo, Y., Hellman, I., Jin, X., Li, Q., Liu, J., Liu, X., Sparsø, T., Tang, M., Wu, H. & 18 others, Wu, R., Yu, C., Zheng, H., Astrup, A., Bolund, L., Holmkvist, J., Jørgensen, T., Kristiansen, Karsten, Schmitz, O., Schwartz, Thue W., Zhang, X., Li, R., Yang, H., Wang, J., Hansen, Torben, Pedersen, Oluf Borbye, Nielsen, Rasmus & Wang, J., 2010, In: Nature Genetics. 42, 11, p. 969-72 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      Targeting CXCR4 in HIV Cell-Entry Inhibition

      Steen, A., Schwartz, Thue W. & Rosenkilde, Mette, 2010, In: Mini reviews in medicinal chemistry. 9, 14, p. 1605-21 16 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    26. Published

      The minor binding pocket: a major player in 7TM receptor activation

      Rosenkilde, Mette, Benned-Jensen, T., Frimurer, T. M. & Schwartz, Thue W., 2010, In: Trends in Pharmacological Sciences. 31, 12, p. 567-574 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    27. 2009
    28. Published

      Construction of covalently coupled, concatameric dimers of 7TM receptors

      Terpager, M., Scholl, D. J., Kubale, V., Martini, L., Elling, C. E. & Schwartz, Thue W., 2009, In: Journal of Receptors and Signal Transduction. 29, 5, p. 235-45 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    29. Published

      G protein-coupled receptor 39 deficiency is associated with pancreatic islet dysfunction

      Holst, Birgitte, Egerod, Kristoffer Lihme, Jin, C., Petersen, P. S., Østergaard, M. V., Hald, J., Sprinkel, A. M. E., Størling, J., Mandrup-Poulsen, Thomas, Holst, Jens Juul, Thams, P., Orskov, C., Wierup, N., Sundler, F., Madsen, O. D. & Schwartz, Thue W., 2009, In: Endocrinology. 150, 6, p. 2577-85 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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    ID: 11601