Thue W. Schwartz
Professor
Schwartz Group
Blegdamsvej 3B, Mærsk Tårnet, 6. sal, 2200 København N.
Member of:
- 2006
- Published
Ghrelin receptor inverse agonists: identification of an active peptide core and its interaction epitopes on the receptor
Holst, Birgitte, Lang, M., Brandt, E., Bach, Anders, Howard, A., Frimurer, T. M., Beck-Sickinger, A. & Schwartz, Thue W., 2006, In: Molecular Pharmacology. 70, 3, p. 936-46 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ghrelin receptor mutations--too little height and too much hunger
Holst, Birgitte & Schwartz, Thue W., 2006, In: Journal of Clinical Investigation. 116, 3, p. 637-41 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GluVII : 06 - a highly conserved and selective anchor point for non-peptide ligands in chemokine receptors
Rosenkilde, Mette & Schwartz, Thue W., 2006, In: Current Topics in Medicinal Chemistry. 6, 13, p. 1319-1333 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GluVII:06--a highly conserved and selective anchor point for non-peptide ligands in chemokine receptors
Rosenkilde, Mette & Schwartz, Thue W., 2006, In: Current Topics in Medicinal Chemistry. 6, 13, p. 1319-33 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metal ion site engineering indicates a global toggle switch model for seven-transmembrane receptor activation
Elling, C. E., Frimurer, T. M., Gerlach, L., Jorgensen, R., Holst, Birgitte & Schwartz, Thue W., 2006, In: Journal of Biological Chemistry. 281, 25, p. 17337-46 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular mechanism of 7TM receptor activation--a global toggle switch model
Schwartz, Thue W., Frimurer, T. M., Holst, Birgitte, Rosenkilde, Mette & Elling, C. E., 2006, In: Annual Review of Pharmacology and Toxicology. 46, p. 481-519 38 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular pharmacological phenotyping of EBI2. An orphan seven-transmembrane receptor with constitutive activity
Rosenkilde, Mette, Benned-Jensen, T., Holst, Peter Johannes, Kledal, T. N., Lüttichau, H. R., Larsen, J. K., Christensen, Jan Pravsgaard, Schwartz, Thue W. & Andersen, H., 2006, In: Journal of Biological Chemistry. 281, 19, p. 13199-208 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The PP-fold solution structure of human polypeptide YY and human PYY3-36 as determined by NMR
Nygaard, R., Nielbo, S., Schwartz, Thue W. & Poulsen, F. M., 2006, In: Biochemistry. 45, 27, p. 8350-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2005
- Published
The human herpes virus 8-encoded chemokine receptor is required for angioproliferation in a murine model of Kaposi's sarcoma.
Jensen, K., Manfra, D., Grisotto, M., Martin, A., Vassileva, G., Kelley, K., Schwartz, Thue W. & Lira, S., Mar 2005, In: Journal of immunology (Baltimore, Md. : 1950).Research output: Contribution to journal › Journal article › Research › peer-review
- Published
AMD3465, a monomacrocyclic CXCR4 antagonist and potent HIV entry inhibitor
Hatse, S., Princen, K., De Clercq, E., Rosenkilde, Mette, Schwartz, Thue W., Hernandez-Abad, P. E., Skerlj, R. T., Bridger, G. J. & Schols, D., 2005, In: Biochemical Pharmacology. 70, 5, p. 752-61 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
CC and CX3C chemokines differentially interact with the N terminus of the human cytomegalovirus-encoded US28 receptor
Casarosa, P., Waldhoer, M., LiWang, P. J., Vischer, H. F., Kledal, T., Timmerman, H., Schwartz, Thue W., Smit, M. J. & Leurs, R., 2005, In: Journal of Biological Chemistry. 280, 5, p. 3275-3285 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of glucagon-like peptide-1 receptor beta-arrestin 2 interaction: a high-affinity receptor phenotype
Jorgensen, R., Martini, L., Schwartz, Thue W. & Elling, C. E., 2005, In: Molecular Endocrinology. 19, 3, p. 812-23 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterizaton of glucagon-like peptide-1 receptor beta-arrestin 2 interaction: a high-affinity receptor phenotype
Jorgensen, R., Martini, L., Schwartz, Thue W. & Elling, C. E., 2005, In: Molecular Endocrinology. Vol. 19, no.3, p. 812-23Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High constitutive activity of a virus-encoded seven transmembrane receptor in the absence of the conserved DRY motif (Asp-Arg-Tyr) in transmembrane helix 3
Rosenkilde, Mette, Kledal, T. N. & Schwartz, Thue W., 2005, In: Molecular Pharmacology. 68, 1, p. 11-9 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nonpeptide and peptide growth hormone secretagogues act both as ghrelin receptor agonist and as positive or negative allosteric modulators of ghrelin signaling
Holst, Birgitte, Brandt, E., Bach, Anders, Heding, A. & Schwartz, Thue W., 2005, In: Molecular Endocrinology. 19, 9, p. 2400-11 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Studies of relationships between variation of the human G protein-coupled receptor 40 Gene and Type 2 diabetes and insulin release
Hamid, Y. H., Vissing, H., Holst, Birgitte, Urhammer, S. A., Pyke, C., Hansen, S. K., Glümer, C., Borch-Johnsen, K., Jørgensen, T., Schwartz, Thue W., Pedersen, O. & Hansen, Torben, 2005, In: Diabetic Medicine. 22, 1, p. 74-80 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The human herpes virus 8-encoded chemokine receptor is required for angioproliferation in a murine model of Kaposi's sarcoma
Jensen, K. K., Manfra, D. J., Grisotto, M. G., Martin, A. P., Vassileva, G., Kelley, K., Schwartz, Thue W. & Lira, S. A., 2005, In: Journal of Immunology. 174, 6, p. 3686-94 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The human herpes virus 8-encoded chemokine receptor is required for angioproliferation in a murine model of Kaposis sarcoma
Jensen, K. K., Manfra, D. J., Grisotto, M. G., Martin, A. P., Vassileva, G., Kelley, K., Schwartz, Thue W. & Lira, S. A., 2005, In: Journal of Immunology. Vol. 174, no. 6, p. 3686-94Research output: Contribution to journal › Journal article › Research › peer-review
- 2004
- Published
A library of 7TM receptor C-terminal tails. Interactions with the proposed post-endocytic sorting proteins ERM-binding phosphoprotein 50 (EBP50), N-ethylmaleimide-sensitive factor (NSF), sorting nexin 1 (SNX1), and G protein-coupled receptor-associated sorting protein (GASP)
Heydorn, A., Søndergaard, B. P., Ersbøll, B., Holst, Birgitte, Nielsen, Finn Cilius, Haft, C. R., Whistler, J. & Schwartz, Thue W., 2004, In: Journal of Biological Chemistry. 279, 52, p. 54291-303 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Common structural basis for constitutive activity of the ghrelin receptor family
Holst, Birgitte, Holliday, N. D., Bach, Anders, Elling, C. E., Cox, H. M. & Schwartz, Thue W., 2004, In: Journal of Biological Chemistry. 279, 51, p. 53806-17 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Constitutive and regulated activities of virus-encoded 7TM receptors
Rosenkilde, Mette & Schwartz, Thue W., 2004, Handbook of Cellular Signalling. Chapter 29 ed. p. 173-76Research output: Chapter in Book/Report/Conference proceeding › Report chapter › Research
- Published
Constitutive ghrelin receptor activity as a signaling set-point in appetite regulation
Holst, Birgitte & Schwartz, Thue W., 2004, In: TIPS - Trends in Pharmacological Sciences. 25, 3, p. 113-7 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Det chemokine system - en vigtig regulator af angiogenese i sundhed og sygdom
Rosenkilde, Mette & Schwartz, Thue W., 2004, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 112, 7-8, p. 481-95 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Distinct in vitro interaction pattern of dopamine receptor subtypes with adaptor proteins involved in post-endocytotic receptor targeting
Heydorn, A., Søndergaard, B. P., Hadrup, N., Holst, Birgitte, Haft, C. R. & Schwartz, Thue W., 2004, In: FEBS Letters. 556, 1-3, p. 276-80 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibition of human immunodeficiency virus replication by a dual CCR5/CXCR4 antagonist
Princen, K., Hatse, S., Vermeire, K., Aquaro, S., De Clercq, E., Gerlach, L., Rosenkilde, Mette, Schwartz, Thue W., Skerlj, R., Bridger, G. & Schols, D., 2004, In: Journal of Virology. 78, 23, p. 12996-3006 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 11601
Most downloads
-
4519
downloads
Family and population-based studies of variation within the ghrelin receptor locus in relation to measures of obesity
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
2786
downloads
PDZ domain-mediated interactions of G protein-coupled receptors with postsynaptic density protein 95: quantitative characterization of interactions
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
607
downloads
Receptor structure-based discovery of non-metabolite agonists for the succinate receptor GPR91
Research output: Contribution to journal › Journal article › Research › peer-review
Published