Exercise-induced phospho-proteins in skeletal muscle

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Exercise-induced phospho-proteins in skeletal muscle. / Deshmukh, A S; Hawley, J A; Zierath, J R.

In: International Journal of Obesity, Vol. 32, No. Suppl. 4, 2008, p. S18-S23.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Deshmukh, AS, Hawley, JA & Zierath, JR 2008, 'Exercise-induced phospho-proteins in skeletal muscle', International Journal of Obesity, vol. 32, no. Suppl. 4, pp. S18-S23. https://doi.org/10.1038/ijo.2008.118

APA

Deshmukh, A. S., Hawley, J. A., & Zierath, J. R. (2008). Exercise-induced phospho-proteins in skeletal muscle. International Journal of Obesity, 32(Suppl. 4), S18-S23. https://doi.org/10.1038/ijo.2008.118

Vancouver

Deshmukh AS, Hawley JA, Zierath JR. Exercise-induced phospho-proteins in skeletal muscle. International Journal of Obesity. 2008;32(Suppl. 4):S18-S23. https://doi.org/10.1038/ijo.2008.118

Author

Deshmukh, A S ; Hawley, J A ; Zierath, J R. / Exercise-induced phospho-proteins in skeletal muscle. In: International Journal of Obesity. 2008 ; Vol. 32, No. Suppl. 4. pp. S18-S23.

Bibtex

@article{f1f1b679ab484b87b318fdf387b878af,
title = "Exercise-induced phospho-proteins in skeletal muscle",
abstract = "Efforts to identify exercise-induced signaling events in skeletal muscle have been influenced by ground-breaking discoveries in the insulin action field. Initial discoveries demonstrating that exercise enhances insulin sensitivity raised the possibility that contraction directly modulates insulin receptor signaling events. Although the acute effects of exercise on glucose metabolism are clearly insulin-independent, the canonical insulin signaling cascade has been used as a framework by investigators in an attempt to resolve the mechanisms by which muscle contraction governs glucose metabolism. This review focuses on recent advances in our understanding of exercise-induced signaling pathways governing glucose metabolism in skeletal muscle. Particular emphasis will be placed on the characterization of AS160, a novel Akt substrate that plays a role in the regulation of glucose transport.",
keywords = "Animals, Exercise, GTPase-Activating Proteins, Glucose, Humans, Mice, Muscle Contraction, Muscle, Skeletal, Protein Kinases, Proto-Oncogene Proteins c-akt, Signal Transduction, Journal Article, Research Support, Non-U.S. Gov't, Review",
author = "Deshmukh, {A S} and Hawley, {J A} and Zierath, {J R}",
year = "2008",
doi = "10.1038/ijo.2008.118",
language = "English",
volume = "32",
pages = "S18--S23",
journal = "International Journal of Obesity",
issn = "0307-0565",
publisher = "nature publishing group",
number = "Suppl. 4",

}

RIS

TY - JOUR

T1 - Exercise-induced phospho-proteins in skeletal muscle

AU - Deshmukh, A S

AU - Hawley, J A

AU - Zierath, J R

PY - 2008

Y1 - 2008

N2 - Efforts to identify exercise-induced signaling events in skeletal muscle have been influenced by ground-breaking discoveries in the insulin action field. Initial discoveries demonstrating that exercise enhances insulin sensitivity raised the possibility that contraction directly modulates insulin receptor signaling events. Although the acute effects of exercise on glucose metabolism are clearly insulin-independent, the canonical insulin signaling cascade has been used as a framework by investigators in an attempt to resolve the mechanisms by which muscle contraction governs glucose metabolism. This review focuses on recent advances in our understanding of exercise-induced signaling pathways governing glucose metabolism in skeletal muscle. Particular emphasis will be placed on the characterization of AS160, a novel Akt substrate that plays a role in the regulation of glucose transport.

AB - Efforts to identify exercise-induced signaling events in skeletal muscle have been influenced by ground-breaking discoveries in the insulin action field. Initial discoveries demonstrating that exercise enhances insulin sensitivity raised the possibility that contraction directly modulates insulin receptor signaling events. Although the acute effects of exercise on glucose metabolism are clearly insulin-independent, the canonical insulin signaling cascade has been used as a framework by investigators in an attempt to resolve the mechanisms by which muscle contraction governs glucose metabolism. This review focuses on recent advances in our understanding of exercise-induced signaling pathways governing glucose metabolism in skeletal muscle. Particular emphasis will be placed on the characterization of AS160, a novel Akt substrate that plays a role in the regulation of glucose transport.

KW - Animals

KW - Exercise

KW - GTPase-Activating Proteins

KW - Glucose

KW - Humans

KW - Mice

KW - Muscle Contraction

KW - Muscle, Skeletal

KW - Protein Kinases

KW - Proto-Oncogene Proteins c-akt

KW - Signal Transduction

KW - Journal Article

KW - Research Support, Non-U.S. Gov't

KW - Review

U2 - 10.1038/ijo.2008.118

DO - 10.1038/ijo.2008.118

M3 - Journal article

C2 - 18719593

VL - 32

SP - S18-S23

JO - International Journal of Obesity

JF - International Journal of Obesity

SN - 0307-0565

IS - Suppl. 4

ER -

ID: 170597707