Thomas Michael Frimurer
Associate Professor
Platforms
Blegdamsvej 3B, Mærsk Tårnet, 6-7-8. sal, 2200 København N.
Member of:
Introductory remarks on publicationslist
Publications: Author or co-author on > 40 papers in peer-reviewed, medium to high profile scientific journals. Involved in innovation and commercialization activities. Patents: Author or co-author on > 15 patents on chemical leads and drug candidates for the treatment of obesity, type-2 diabetes, asthma inflammation and pain. Most recently (Mar. 2014) we patented a strong chemical package on oral available small molecule GPR39 agonists – a potential obesity and type-2 diabetes target. Invited talks: Participated in multiple oral presentations at international and national scientific meetings.
- Published
Structural basis for constitutive activity and agonist-induced activation of the enteroendocrine fat sensor GPR119
Engelstoft, M. S., Norn, C., Pedersen, M. H., Holliday, N. D., Elster, L., Lehmann, J., Jones, R. M., Frimurer, Thomas Michael & Schwartz, Thue W., Dec 2014, In: British Journal of Pharmacology. 171, 24, p. 5774-89 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gating function of isoleucine-116 in TM-3 (position III:16/3.40) for the activity state of the CC-chemokine receptor 5 (CCR5)
Steen, A., wbf943, wbf943, Thiele, S., Guo, D., Frimurer, Thomas Michael & Rosenkilde, Mette, Mar 2014, In: British Journal of Pharmacology. 171, 6, p. 1566-79 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 34520257
Most downloads
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609
downloads
Receptor structure-based discovery of non-metabolite agonists for the succinate receptor GPR91
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
143
downloads
Structure-Activity Investigations and Optimisations of Non-metabolite Agonists for the Succinate Receptor 1
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
132
downloads
Molecular dynamics-guided discovery of an ago-allosteric modulator for GPR40/FFAR1
Research output: Contribution to journal › Journal article › Research › peer-review
Published