Jens Juul Holst
Professor
Endocrinology and Metabolism
Blegdamsvej 3
2200 København N.
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Glucose-dependent insulinotropic polypeptide (GIP) induces lipolysis during stable basal insulin substitution and hyperglycemia in men with type 1 diabetes: a randomized, double-blind, placebo-controlled, crossover clinical trial
Heimburger, S. M., Nielsen, C. N., Calanna, S., Holst, Jens Juul, Vilsbøll, Tina, Knop, Filip Krag & Christensen, Mikkel Bring, 2022, In: Diabetes, Obesity and Metabolism. 24, 1, p. 142-147Research output: Contribution to journal › Journal article › Research › peer-review
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The effect of 6-day subcutaneous glucose-dependent insulinotropic polypeptide infusion on time in glycaemic range in patients with type 1 diabetes: a randomised, double-blind, placebo-controlled crossover trial
Heimbürger, S. M. N., Hoe, B., Nielsen, C. N., Bergmann, N. C., Hartmann, Bolette, Holst, Jens Juul, Vilsbøll, Tina, Dejgaard, T. F., Christensen, Mikkel Bring & Knop, Filip Krag, 2021, In: Diabetologia. 64, p. 2425-2431Research output: Contribution to journal › Journal article › Research › peer-review
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GIP affects hepatic fat and brown adipose tissue thermogenesis, but not white adipose tissue transcriptome in T1D
Heimbürger, S. M. N., Hoe, B., Nielsen, C. N., Bergman, N. C., Skov-Jeppesen, Kirsa, Hartmann, Bolette, Holst, Jens Juul, Dela, Flemming, Overgaard, J., Størling, Joachim, Vilsbøll, Tina, Dejgaard, T. F., Havelund, J. F., Gorshkov, V., Kjeldsen, F., Færgeman, N. J. K., Madsen, M. R., Christensen, Mikkel Bring & Knop, Filip Krag, 2022, In: Journal of Clinical Endocrinology and Metabolism. 107, 12, p. 3261–3274Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of glucagon immunoneutralization on the increase in urea synthesis after hysterectomy in rats
Heindorff, H., Holst, Jens Juul, Almdal, T. P. & Vilstrup, H., 1993, In: European Journal of Clinical Investigation. 23, p. 166-170Research output: Contribution to journal › Journal article › Research › peer-review
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No effect of the turmeric root phenol curcumin on prednisolone-induced gluco-metabolic perturbations in men with overweight or obesity
Hellmann, P. H., Bagger, J. I., Carlander, K. R., Hansen, K. B., Forman, Julie Lyng, Størling, Joachim, Chabanova, E., Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2023, In: Endocrine Connections. 12, 4, e220334.Research output: Contribution to journal › Journal article › Research › peer-review
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The effect of curcumin on hepatic fat content in individuals with obesity
Hellmann, P. H., Bagger, J. I., Carlander, K. R., Forman, Julie Lyng, Chabanova, E., Svenningsen, J. S., Holst, Jens Juul, Gillum, M. P., Vilsbøll, Tina & Knop, Filip Krag, 2022, In: Diabetes, Obesity and Metabolism. 24, 11, p. 2192-2202 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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GLP-1 suppresses gastrointestinal motility and inhibits the migrating motor complex in healthy subjects and patients with irritable bowel syndrome
Hellstrom, P. M., Naslund, E., Edholm, T., Schmidt, P. T., Kristensen, J., Theodorsson, E., Holst, Jens Juul & Efendic, S., 2008, In: Neurogastroenterology and Motility. 20, 6, p. 649-659 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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GLP-1 suppresses gastrointestinal motility and inhibits the migrating motor complex in healthy subjects and patients with irritable bowel syndrome
Hellström, P. M., Näslund, E., Edholm, T., Schmidt, P. T., Kristensen, J., Theodorsson, E., Holst, Jens Juul & Efendic, S., Jun 2008, In: Neurogastroenterology and Motility Online. 20, 6, p. 649-59 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The role of the incretins in the postprandial bone remodelling
Helsted, M. M., Gasbjerg, Lærke Smidt, Lanng, A. R., Stensen, S., Hartmann, Bolette, Christensen, Mikkel Bring, Holst, Jens Juul, Vilsbøll, Tina, Rosenkilde, M. M. & Knop, Filip Krag, 2018, In: Diabetologia. 61, S1, p. S221-S221 449.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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The role of endogenous GIP and GLP-1 in postprandial bone homeostasis
Helsted, M. M., Gasbjerg, Lærke Smidt, Lanng, A. R., Bergmann, N. C., Stensen, S., Hartmann, Bolette, Christensen, Mikkel Bring, Holst, Jens Juul, Vilsbøll, Tina, Rosenkilde, Mette & Knop, Filip Krag, 2020, In: Bone. 140, 7 p., 115553.Research output: Contribution to journal › Journal article › Research › peer-review
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Disassociation of bone resorption and formation by GLP-2 - A 14-day study in healthy postmenopausal women
Henriksen, D. B., Alexandersen, P., Hartmann, B., Adrian, C. L., Byrjalsen, I., Bone, H. G., Holst, Jens Juul & Christiansen, C., 2007, In: Bone. 40, 3, p. 723-729 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Reduction of nocturnal rise in bone resorption by subcutaneous GLP-2.
Henriksen, D. B., Alexandersen, P., Byrjalsen, I., Hartmann, B., Bone, H. G., Christiansen, C. & Holst, Jens Juul, 2004, In: Bone. 34, 1, p. 140-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Four-month treatment with GLP-2 significantly increases hip BMD: a randomized, placebo-controlled, dose-ranging study in postmenopausal women with low BMD
Henriksen, D. B., Alexandersen, P., Hartmann, Bolette, Adrian, C. L., Byrjalsen, I., Bone, H. G., Holst, Jens Juul & Christiansen, C., 2009, In: Bone. 45, 5, p. 833-42 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Role of gastrointestinal hormones in postprandial reduction of bone resorption
Henriksen, D. B., Alexandersen, P., Bjarnason, N. H., Vilsbøll, Tina, Hartmann, B., Henriksen, E. E. G., Byrjalsen, I., Krarup, T., Holst, Jens Juul & Christiansen, C., 1 Dec 2003, In: J Bone Miner Res. 18, 12, p. 2180-2190 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Disassociation of bone resorption and formation by GLP-2: a 14-day study in healthy postmenopausal women
Henriksen, D. B., Alexandersen, P., Hartmann, Bolette, Adrian, C. L., Byrjalsen, I., Bone, H. G., Holst, Jens Juul & Christiansen, C., Mar 2007, In: Bone. 40, 3, p. 723-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Glucose mediated glucose disposal in insulin resistant normoglycemic relatives of type 2 diabetic patients
Henriksen, J. E., Levin, K., Thye-Rønn, P., Alford, F., Hother-Nielsen, O., Holst, Jens Juul & Beck-Nielsen, H., 2000, In: Diabetes. 49, p. 1209-1218Research output: Contribution to journal › Journal article › Research › peer-review
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Elevated circulating leptin in arterial hypertension: relationship to arteriovenous overflow and extraction of leptin
Henriksen, J. H., Holst, Jens Juul, Møller, S., Jensen, G. & Bendtsen, Flemming, 2000, In: Clin.Sci.. 99, p. 527-534Research output: Contribution to journal › Journal article › Research › peer-review
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Increased Circulating leptin in cirrhosis: relation to release and disposal
Henriksen, J. H., Holst, Jens Juul, Møller, S., Brinch, K. & Bendtsen, Flemming, 1999, In: Hepatology. 29, p. 1818-1824Research output: Contribution to journal › Journal article › Research › peer-review
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Elevated ciculating leptin levels in arterial hypertension: relationship to arteriovenous overflow and extraction of leptin
Henriksen, J. H., Holst, Jens Juul & Moller, S., 2001, In: Clin.Sci.. 99, p. 527-534Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of saxagliptin on β-cell stimulation and insulin secretion in patients with type 2 diabetes
Henry, R. R., Smith, S., Schwartz, S., Mudaliar, S. R., Deacon, Carolyn F., Holst, Jens Juul, Duan, R. Y., Chen, R. S. & List, J. F., 2011, In: Diabetes, Obesity and Metabolism. 13, 9, p. 850-858 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of single oral doses of sitagliptin, a dipeptidyl peptidase-4 inhibitor, on incretin and plasma glucose levels after an oral glucose tolerance test in patients with type 2 diabetes.
Herman, G. A., Bergman, A., Stevens, C., Kotey, P., Yi, B., Zhao, P., Dietrich, B., Golor, G., Schrodter, A., Keymeulen, B., Lasseter, K. C., Kipnes, M. S., Snyder, K., Hilliard, D., Tanen, M., Cilissen, C., De Smet, M., de Lepeleire, I., Van Dyck, K., Wang, A. Q. & 7 others, , 2006, In: Journal of Clinical Endocrinology and Metabolism. 91, 11, p. 4612-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Postprandial Dyslipidemia, Hyperinsulinemia, and Impaired Gut Peptides/Bile Acids in Adolescents with Obesity
Higgins, V., Asgari, S., Hamilton, J. K., Wolska, A., Remaley, A. T., Hartmann, Bolette, Holst, Jens Juul & Adeli, K., 2020, In: Journal of Clinical Endocrinology & Metabolism. 105, 4, p. 1228-1241Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of topical ropivacaine on eicosanoids and neurotransmitters in the rectum of patients with distal ulcerative colitis
Hillingsø, Jens Georg, Kjeldsen, J., Schmidt, P. T., Rasmussen, T. N., Fisher-Hansen, B., Holst, Jens Juul, Lauristen, K., Bukhave, K. & Rask-Madsen, J., Mar 2002, In: Scandinavian Journal of Gastroenterology. 37, 3, p. 325-9 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Preservation of active Effects of topical ropivacaine om eicosanoids and neurotransmitters in the rectum of patients with distal ulcerative colitis
Hillingsøe, J. G., Kjeldsen, J., Schmidt, P. T., Rasmussen, T. N., Arlander, E., Fischer-Hansen, B., Holst, Jens Juul, Lauritsen, K., Bukhave, K. & Rask-Madsen, J., 2002, In: Scandinavian Journal of Gastroenterology. 37, p. 325-329Research output: Contribution to journal › Journal article › Research › peer-review
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Plasma glucagon and glucose recovery after hypoglycemia: The effect of total autonomic blockade
Hilsted, J., Frandsen, H., Holst, Jens Juul, Christensen, J. & Nielsen, S. L., 1991, In: Acta Endocrinol.. 125, p. 466-469Research output: Contribution to journal › Journal article › Research › peer-review
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Importance of endogenous GLP-1 and GIP for postprandial glucose tolerance after Roux-en-Y gastric bypass and sleeve gastrectomy surgery
Hindso, M., Hedback, N., Moller, A., Svane, M. S., Martinussen, C., Jorgensen, N. B., Dirksen, C., Gasbjerg, Lærke Smidt, Kristiansen, V. B., Hartmann, Bolette, Rosenkilde, Mette, Holst, Jens Juul, Madsbad, Sten & Bojsen-Moller, K. N., 2021, In: Diabetologia. 64, SUPPL 1, p. 200-201 387.Research output: Contribution to journal › Conference abstract in journal › Research
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Effect of 6 weeks of very low-volume high-intensity interval training on oral glucose-stimulated incretin hormone response
Hindsø, M., Kuhlman, A. B., Dohlmann, T. L., Lund, M. T., Hartmann, Bolette, Holst, Jens Juul, Larsen, Steen & Helge, Jørn Wulff, 2022, In: European Journal of Sport Science. 22, 3, p. 381-389Research output: Contribution to journal › Journal article › Research › peer-review
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The importance of endogenously secreted GLP-1 and GIP for postprandial glucose tolerance and β-cell function after Roux-en-Y gastric bypass and sleeve gastrectomy surgery
Hindsø, M., Hedbäck, N., Svane, M. S., Møller, A., Martinussen, C., Jørgensen, N. B., Dirksen, C., Gasbjerg, Lærke Smidt, Kristiansen, V. B., Hartmann, Bolette, Rosenkilde, Mette, Holst, Jens Juul, Madsbad, Sten & Bojsen-Møller, K. N., 2023, In: Diabetes. 72, 3, p. 336–347Research output: Contribution to journal › Journal article › Research › peer-review
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The role of GLP-1 in postprandial glucose metabolism after bariatric surgery: a narrative review of human GLP-1 receptor antagonist studies
Hindsø, M., Svane, M. S., Hedbäck, N., Holst, Jens Juul, Madsbad, Sten & Bojsen-Møller, K. N., 2021, In: Surgery for Obesity and Related Diseases. 17, 7, p. 1383-1391Research output: Contribution to journal › Review › Research › peer-review
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Early effects of Roux-en-Y gastric bypass on dietary fatty acid absorption and metabolism in people with obesity and normal glucose tolerance
Hindsø, M., Bojsen-Møller, K. N., Kristiansen, V. B., Holst, Jens Juul, van Hall, Gerrit & Madsbad, Sten, 2022, In: International Journal of Obesity. 46, 7, p. 1359-1365Research output: Contribution to journal › Journal article › Research › peer-review
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Delayed ß-cell response and glucose intolerance in young women with Turner syndrome
Hjerrild, B. E., Holst, Jens Juul, Juhl, C., Christiansen, J. S., Schmitz, O. & Gravholt, C. H., 2011, In: B M C Endocrine Disorders. 11, p. 11-6 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Dipeptidyl peptidase-4 inhibition increases portal concentrations of intact glucagon-like peptide-1 (GLP-1) to a greater extent than peripheral concentrations in anaesthetised pigs
Hjøllund, K. R., Deacon, Carolyn F. & Holst, Jens Juul, 2011, In: Diabetologia. 54, 8, p. 2206-8 3 p.Research output: Contribution to journal › Letter › Research › peer-review
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The Sensory Mechanisms of Nutrient-Induced GLP-1 Secretion
Hjørne, A. P., Modvig, Ida Marie & Holst, Jens Juul, 2022, In: Metabolites. 12, 5, 15 p., 420.Research output: Contribution to journal › Review › Research › peer-review
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Effects of 1 and 3 g cinnamon on gastric emptying, satiety, and postprandial blood glucose, insulin, glucose-dependent insulinotropic polypeptide, glucagon-like peptide 1, and ghrelin concentrations in healthy subjects
Hlebowicz, J., Hlebowicz, A., Lindstedt, S., Björgell, O., Höglund, P., Holst, Jens Juul, Darwiche, G. & Almér, L., 2009, In: American Journal of Clinical Nutrition. 89, 3, p. 815-21 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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GIP infusion in patients with type 1 diabetes seems to attenuate post-prandial glucose excursions after prandial insulin over-dose and physical activity
Hoe, B., Heimburger, S. M. N., Gasbjerg, L. S., Lanng, A. R., Lynggaard, M. B., Hartmann, Bolette, Holst, Jens Juul, Vilsbøll, Tina, Lund, A., Engberg, S., Dejgaard, T. F., Christensen, Mikkel Bring & Knop, Filip Krag, 2020, In: Diabetologia. 63, Suppl. 1, p. S117 1 p., 232.Research output: Contribution to journal › Conference abstract in journal › Research
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A Placebo-Controlled Study on the Effects of the Glucagon-Like Peptide-1 Mimetic, Exenatide, on Insulin Secretion, Body Composition and Adipokines in Obese, Client-Owned Cats
Hoelmkjaer, K. M., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Cronin, A. M., Nielsen, Dorte Hald, Mandrup-Poulsen, Thomas & Bjørnvad, Charlotte Reinhard, 2 May 2016, In: P L o S One. 11, 5, 18 p., e0154727.Research output: Contribution to journal › Journal article › Research › peer-review
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Gastric bypass surgery has a weight-loss independent effect on post-challenge serum glucose levels
Hofsø, D., Birkeland, K. I., Holst, Jens Juul, Bollerslev, J., Sandbu, R., Røislien, J. & Hjelmesæth, J., 2015, In: Diabetology & Metabolic Syndrome. 7, p. 1-4 4 p., 69.Research output: Contribution to journal › Journal article › Research › peer-review
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A single supplement of a standardised bilberry (Vaccinium myrtillus L.) extract (36 % wet weight anthocyanins) modifies glycaemic response in individuals with type 2 diabetes controlled by diet and lifestyle
Hoggard, N., Cruickshank, M., Moar, K., Bestwick, C., Holst, Jens Juul, Russell, W. & Horgan, G., 2013, In: Journal of Nutritional Science. 2, 9 p., e22.Research output: Contribution to journal › Journal article › Research › peer-review
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Reference intervals for glucose, beta-cell polypeptides, and counterregulatory factors during prolonged fasting
Hojlund, K., Wildner-Christensen, M., Eshoj, O. & Holst, Jens Juul, 2001, In: Am J Physiol-Endoc M. 280, p. E50-E58Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of chemical myenteric ablation on the structure proliferation and endocrine cells in the small intestinal mucosa
Holle, G. E., Demir, I., Dietl, J., Rehfeld, J. F. & Holst, Jens Juul, 1992, Advances in the Innervation of the Gastrointestinal Tract. Aspen PublishersResearch output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
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Effect of chemical myenteric ablation on the structure, proliferation and endocrine cells in the small intestinal mucosa
Holle, G. E., Demir, I., Dietl, J., Forssmann, W. G., Rehfeld, J. F. & Holst, Jens Juul, 1993, In: Advances in the Innervation of the Gastrointestinal Tract. p. 89-98Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of 17-norleucine-VIP on gastroduodenal motility relative to serum VIP concentration and blockade of NOS.
Holle, G. E., Steinbach, E., Wünsch, E. & Holst, Jens Juul, 1995, In: Am. J. Physiol.. 269, p. G584-G590Research output: Contribution to journal › Journal article › Research › peer-review
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Acute differential effects of dietary protein quality on postprandial lipemia in obese non-diabetic subjects
Holmer-Jensen, J., Mortensen, L. S., Astrup, A., de Vrese, M., Holst, Jens Juul, Thomsen, C. & Hermansen, K., 2013, In: Nutrition Research. 33, 1, p. 34-40 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Acute differential effects of milk-derived dietary proteins on postprandial lipaemia in obese non-diabetic subjects
Holmer-Jensen, J., Hartvigsen, M., Mortensen, L. S., Astrup, A., de Vrese, M., Holst, Jens Juul, Thomsen, C. & Hermansen, K., 2012, In: European Journal of Clinical Nutrition. 66, p. 32-38 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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G protein-coupled receptor 39 deficiency is associated with pancreatic islet dysfunction
Holst, Birgitte, Egerod, Kristoffer Lihme, Jin, C., Petersen, P. S., Østergaard, M. V., Hald, J., Sprinkel, A. M. E., Størling, J., Mandrup-Poulsen, Thomas, Holst, Jens Juul, Thams, P., Orskov, C., Wierup, N., Sundler, F., Madsen, O. D. & Schwartz, Thue W., 2009, In: Endocrinology. 150, 6, p. 2577-85 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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On the effects of human galanin in man
Holst, Jens Juul, Bersani, M., Hvidberg, A., Knigge, Ulrich, Christiansen, E. M., Madsbad, Sten, Harling, H. & Kofod, H., 1993, In: Diabetologia. 36, 7, p. 653-657 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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GRP nerves in pig antrum: role of GRP in vagal control of gastrin secretion
Holst, Jens Juul & Poulsen, Steen Seier, Nov 1987, In: American Journal of Physiology (Consolidated). 253, 5 Pt 1, p. G643-9Research output: Contribution to journal › Journal article › Research › peer-review
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GRP-producing nerves control antral somatostatin and gastrin secretion in pigs
Holst, Jens Juul, Ørskov, Cathrine & Poulsen, Steen Seier, Dec 1987, In: American Journal of Physiology (Consolidated). 253, 6 Pt 1, p. G767-74Research output: Contribution to journal › Journal article › Research › peer-review
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On the regulatory functions of neuropeptide Y (NPY) with respect to vascular resistance and exocrine and endocrine secretion in the pig pancreas
Holst, Jens Juul, Ørskov, Cathrine, Knuhtsen, S., Sheikh, S. & Nielsen, O. V., Aug 1989, In: Acta Physiologica Scandinavica. 136, 4, p. 519-26 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Occurrence, distribution and motor effects of galanin in the porcine lower esophageal sphincter
Holst, Jens Juul & Poulsen, Steen Seier, 1989, In: Digestion. 42, 3, p. 151-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 4207
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Meal induced gut hormone secretion is altered in aerobically trained compared to sedentary young healthy males
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Copenhagen study of overweight patients with coronary artery disease undergoing low energy diet or interval training: the randomized CUT-IT trial protocol
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Whole grain-rich diet reduces body weight and systemic low-grade inflammation without inducing major changes of the gut microbiome: a randomised cross-over trial
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