Jens Juul Holst
Professor
Endocrinology and Metabolism
Blegdamsvej 3
2200 København N.
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Liraglutide treatment for the prevention of glucose tolerance deterioration in women with prior gestational diabetes mellitus: A 52-week randomized controlled clinical trial
Foghsgaard, S., Vedtofte, L., Andersen, E. S., Bahne, E., Andreasen, C., Sørensen, A. L., Forman, Julie Lyng, Mathiesen, Elisabeth, Svare, J. A., Clausen, Tine Dalsgaard, Damm, Peter, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2023, In: Diabetes, Obesity and Metabolism. 26, 1, p. 201-214 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Women with prior gestational diabetes mellitus and prediabetes are characterised by a decreased incretin effect
Foghsgaard, S., Vedtofte, L., Andreasen, C., Andersen, E. S., Bahne, E., Bagger, J. I., Svare, J. A., Holst, Jens Juul, Clausen, Tine Dalsgaard, Mathiesen, Elisabeth, Damm, Peter, Knop, Filip Krag & Vilsbøll, Tina, Jul 2017, In: Diabetologia. 60, 7, p. 1344-1353 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of vildagliptin on glucagon concentration during meals in patients with type 1 diabetes
Foley, J. E., Ligueros-Saylan, M., He, Y., Holst, Jens Juul, Deacon, Carolyn F., Dunning, B. E., Leone-Jones, A., Yu, T. & Kelley, D. E., Oct 2008, In: Hormone and Metabolic Research. Supplement. 40, 10, p. 727-30 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of Vildagliptin on Glucagon Concentration During Meals in Patients with Type 1 Diabetes
Foley, J. E., Ligueros-Saylan, M., He, Y. L., Holst, Jens Juul, Deacon, Carolyn F., Dunning, B. E., Leone-Jones, A., Yu, T. & Kelley, D. E., 2008, In: Hormone and Metabolic Research. 40, 10, p. 727-730 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Combinatorial, additive and dose-dependent drug–microbiome associations
Forslund, S. K., Chakaroun, R., Zimmermann-Kogadeeva, M., Markó, L., Aron-Wisnewsky, J., Nielsen, T., Moitinho-Silva, L., Schmidt, T. S. B., Falony, G., Vieira-Silva, S., Adriouch, S., Alves, R. J., Assmann, K., Bastard, J. P., Birkner, T., Caesar, R., Chilloux, J., Coelho, L. P., Fezeu, L., Galleron, N. & 23 others, , 2021, In: Nature. 600, p. 500-517 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Circulating Levels of the Soluble Receptor for AGE (sRAGE) during Escalating Oral Glucose Dosages and Corresponding Isoglycaemic i.v. Glucose Infusions in Individuals with and without Type 2 Diabetes
Fotheringham, A. K., Bagger, J. I., Borg, D. J., McCarthy, D. A., Holst, Jens Juul, Vilsbøll, Tina, Knop, Filip Krag & Forbes, J. M., 2020, In: Nutrients. 12, 10, 12 p., 2928.Research output: Contribution to journal › Journal article › Research › peer-review
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Twelve-Week Treatment With Liraglutide as Add-on to Insulin in Normal-Weight Patients With Poorly Controlled Type 1 Diabetes: A Randomized, Placebo-Controlled, Double-Blind Parallel Study
Frandsen, C. S., Dejgaard, T. F., Holst, Jens Juul, Andersen, H. U., Thorsteinsson, B. & Madsbad, Sten, Dec 2015, In: Diabetes Care. 38, 12, p. 2250-7 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Non-insulin pharmacological therapies for treating type 1 diabetes
Frandsen, C. S., Dejgaard, T. F., Madsbad, Sten & Holst, Jens Juul, 2018, In: Expert Opinion on Pharmacotherapy. 19, 9, p. 947-960Research output: Contribution to journal › Review › Research › peer-review
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Liraglutide as adjunct to insulin treatment in type 1 diabetes does not interfere with glycaemic recovery or gastric emptying rate during hypoglycaemia: a randomised, placebo-controlled, double-blind, parallel-group study
Frandsen, C. S., Dejgaard, T. F., Andersen, H. U., Holst, Jens Juul, Hartmann, Bolette, Thorsteinsson, B. & Madsbad, Sten, 17 Mar 2017, In: Diabetes, Obesity and Metabolism. 19, 6, p. 773-782 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Extreme duration exercise affects old and younger men differently
Frandsen, J., Sahl, R. E., Rømer, T., Thunestvedt Hansen, M., Nielsen, A. B., Lie-Olesen, M. M., Rasmusen, H. K., Søgaard, D., Ingersen, A., Rosenkilde, M., Westerterp, K., Holst, J. J., Andersen, J. L., Markowski, A. R., Blachnio-Zabielska, A., Clemmensen, C., Sacchetti, M., Cataldo, A., Traina, M., Larsen, S. & 2 others, , 2022, In: Acta Physiologica. 235, 3, e13816.Research output: Contribution to journal › Journal article › Research › peer-review
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The influence of glucagon on postprandial hyperglycaemia in children 5 years after onset of type 1 diabetes
Fredheim, S., Andersen, M. M., Pörksen, S., Nielsen, L. B., Pipper, C., Hansen, L., Holst, Jens Juul, Thomsen, J., Johannesen, Jesper, Mortensen, H. B. & Svensson, Jannet, 2015, In: Diabetologia. 58, 4, p. 828-34 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of whey on blood glucose and insulin responses to composite breakfast and lunch meals in type 2 diabetic subjects.
Frid, A. H., Nilsson, M., Holst, Jens Juul & Björck, I. M. E., 2005, In: American Journal of Clinical Nutrition. 82, 1, p. 69-75 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Attenuated processing of proglucagon and glucagon-like peptide- 1 in carboxypeptidase E-deficient mice
Friis-Hansen, L., Lacourse, K. A., Samuelson, L. C. & Holst, Jens Juul, 2001, In: J. Endocrinol.. 169, p. 595-602Research output: Contribution to journal › Journal article › Research › peer-review
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Adult glucose metabolism in extremely birthweight-discordant monozygotic twins
Frost, M., Petersen, I., Brixen, K., Beck-Nielsen, H., Holst, Jens Juul, Christiansen, L., Højlund, K. & Christensen, K., Dec 2012, In: Diabetologia. 55, 12, p. 3204-12 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of liraglutide on ectopic fat in polycystic ovary syndrome: A randomized clinical trial
Frøssing, S., Nylander, M., Chabanova, E., Frystyk, J., Holst, Jens Juul, Kistorp, Caroline Michaela Nervil, Skouby, Sven O. & Faber, Jens, Jan 2018, In: Diabetes, Obesity and Metabolism. 20, 1, p. 215-218Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of whey protein and dietary fiber intake on insulin sensitivity, body composition, energy expenditure, blood pressure, and appetite in subjects with abdominal obesity
Fuglsang-Nielsen, R., Rakvaag, E., Langdahl, B., Knudsen, K. E. B., Hartmann, Bolette, Holst, Jens Juul, Hermansen, K. & Gregersen, S., 2021, In: European Journal of Clinical Nutrition. 75, p. 611–619Research output: Contribution to journal › Journal article › Research › peer-review
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Consumption of nutrients and insulin resistance suppress markers of bone turnover in subjects with abdominal obesity
Fuglsang-Nielsen, R., Rakvaag, E., Vestergaard, P., Hartmann, Bolette, Holst, Jens Juul, Hermansen, K., Gregersen, S. & Starup-Linde, J., 2020, In: Bone. 133, 9 p., 115230.Research output: Contribution to journal › Journal article › Research › peer-review
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Defective prohormone processing and altered pancreatic islet morphology in mice lacking active SPC2.
Furuta, M., Yano, H., Zhou, A., Rouille, Y., Holst, Jens Juul, Carroll, R., Ravazzolla, M., Orci, L. & Steiner, D. F., 1997, In: Proc. Natl. Acad. Sci.. 94, p. 6646-6651Research output: Contribution to journal › Journal article › Research › peer-review
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Glucagon-Like Peptide-1 (GLP-1) Response to Oral Glucose is Reduced in Pre-diabetes, Screen-detected Type 2 Diabetes and Obesity, and Influenced by Sex: The ADDITION-PRO Study
Færch, K., Torekov, Signe Sørensen, Vistisen, D., Johansen, N. B., Witte, D. R., Jonsson, Anna Elisabet, Pedersen, Oluf Borbye, Hansen, Torben, Lauritzen, T., Sandbæk, A., Holst, Jens Juul & Jørgensen, M. E., Jul 2015, In: Diabetes. 64, p. 2513-25 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of angiotensin II receptor blockade on cerebral, cardiovascular, counter-regulatory, and symptomatic responses during hypoglycaemia in patients with type 1 diabetes
Færch, L. H., Thorsteinsson, B., Tarnow, L., Holst, Jens Juul, Kjær, T. W., Kanters, Jørgen K., Larroude, C., Dela, Flemming & Pedersen-Bjergaard, Ulrik, Dec 2015, In: Journal of the Renin-Angiotensin-Aldosterone System. 16, 4, p. 1036-1045 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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GIP and GLP-2 together improve bone turnover in humans supporting GIPR-GLP-2R co-agonists as future osteoporosis treatment
Gabe, M. B. N., Skov-Jeppesen, Kirsa, Gasbjerg, Lærke Smidt, Schiellerup, S. P., Martinussen, C., Gadgaard, S., Boer, G. A., Oeke, J., Pedersen, Lola Julie Torz, Veedfald, Simon, Svane, M. S., Bojsen-Møller, K. N., Madsbad, Sten, Holst, Jens Juul, Hartmann, Bolette & Rosenkilde, M. M., 2022, In: Pharmacological Research. 176, 106058.Research output: Contribution to journal › Journal article › Research › peer-review
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Biased GLP-2 agonist with strong G protein-coupling but impaired arrestin recruitment and receptor desensitization enhances intestinal growth in mice
Gabe, M. B. N., Christensen, Liv von Voss, Dal, Jenna Elizabeth Hunt, Gadgaard, S., Gasbjerg, Lærke Smidt, Holst, Jens Juul, Kissow, Hannelouise, Hartmann, Bolette & Rosenkilde, Mette, Jan 2023, In: British Journal of Pharmacology. 180, 13, p. 1674-1689Research output: Contribution to journal › Journal article › Research › peer-review
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N-terminal alterations turn the gut hormone GLP-2 into an antagonist with gradual loss of GLP-2 receptor selectivity towards more GLP-1 receptor interaction
Gabe, M. B. N., Gasbjerg, Lærke Smidt, Gadgaard, S., Lindquist, Peter, Holst, Jens Juul & Rosenkilde, Mette, 2022, In: British Journal of Pharmacology. 179, 18, p. 4473-4485Research output: Contribution to journal › Journal article › Research › peer-review
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Novel agonist- and antagonist-based radioligands for the GLP-2 receptor - useful tools for studies of basic GLP-2R pharmacology
Gadgaard, S., van der Velden, W. J. C., Schiellerup, S. P., Dal, Jenna Elizabeth Hunt, Gabe, M. B. N., Windeløv, Johanne Agerlin, Boer, G. A., Kissow, Hannelouise, Ørskov, Cathrine, Holst, Jens Juul, Hartmann, Bolette & Rosenkilde, M. M., 2022, In: British Journal of Pharmacology. 179, 9, p. 1998-2015Research output: Contribution to journal › Journal article › Research › peer-review
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Long-acting agonists of human and rodent GLP-2 receptors for studies of the physiology and pharmacological potential of the GLP-2 system
Gadgaard, S., Windeløv, Johanne Agerlin, Schiellerup, S. P., Holst, Jens Juul, Hartmann, Bolette & Rosenkilde, Mette, 2023, In: Biomedicine and Pharmacotherapy. 160, 13 p., 114383.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 4207
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Meal induced gut hormone secretion is altered in aerobically trained compared to sedentary young healthy males
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2909
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Copenhagen study of overweight patients with coronary artery disease undergoing low energy diet or interval training: the randomized CUT-IT trial protocol
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694
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Whole grain-rich diet reduces body weight and systemic low-grade inflammation without inducing major changes of the gut microbiome: a randomised cross-over trial
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