Jens Juul Holst
Professor
Endocrinology and Metabolism
Blegdamsvej 3
2200 København N.
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Pancreatic polypeptide responses to isoglycemic oral and intravenous glucose in humans with and without intact vagal innervation
Veedfald, Simon, Plamboeck, A., Hartmann, Bolette, Svendsen, Lars Bo, Vilsbøll, T., Knop, Filip Krag & Holst, Jens Juul, Sep 2015, In: Peptides. 71, p. 229-31 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Pancreatic polypeptide: A potential biomarker of glucose-dependent insulinotropic polypeptide receptor activation in vivo
Veedfald, Simon, Bergmann, N. C., Vilsbøll, Tina, Christensen, Mikkel Bring, Holst, Jens Juul & Knop, Filip Krag, May 2021, In: Diabetic Medicine Online. 38, 8, e14592.Research output: Contribution to journal › Letter › Research › peer-review
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Cephalic phase secretion of insulin and other enteropancreatic hormones in humans
Veedfald, Simon, Plamboeck, A., Deacon, Carolyn F., Hartmann, Bolette, Knop, Filip Krag, Vilsbøll, Tina & Holst, Jens Juul, 1 Jan 2016, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 310, 1, p. G43-51Research output: Contribution to journal › Journal article › Research › peer-review
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Gut hormone secretion, gastric emptying and glucose absorption after frequently sampled oral glucose and liquid mixed meal tests in young men: [Meeting Abstract]
Veedfald, Simon, Rehfeld, Jens Frederik, vanHall, G., Svendsen, Lars Bo & Holst, Jens Juul, 2020, In: Neurogastroenterology and Motility. 32, SI, p. 56 1 p., 146.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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Glucagon-like peptide-2 induces rapid digestive adaptation following intestinal resection in preterm neonates
Vegge, A., Thymann, Thomas, Lund, P., Stoll, B., Bering, S. B., Hartmann, Bolette, Jelsing, J., Qvist, N., Burrin, D. G., Jeppesen, Palle Bekker, Holst, Jens Juul & Sangild, Per Torp, 2013, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 305, 4, p. G277-G285 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of glucagon-like peptide-1-(7,36)-amide on glucose effectiveness and insulin action in people with type 2 diabetes mellitus
Vella, A., Shah, P., Basu, R., Basu, A., Holst, Jens Juul & Rizza, R. A., 2000, In: Diabetes. 49, p. 611-617Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of glucagon-like peptide- 1 (7-36)-amide on initial splanchnic glucose uptake and insulin action in humans with type 1 diabetes
Vella, A., Shah, P., Basu, R. & Holst, Jens Juul, 2001, In: Diabetes. 50, p. 565-572Research output: Contribution to journal › Journal article › Research › peer-review
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Propionate absorbed from the colon acts as gluconeogenic substrate in a strict carnivore, the domestic cat (Felis catus)
Verbrugghe, A., Hesta, M., Daminet, S., Polis, I., Holst, Jens Juul, Buyse, J., Wuyts, B. & Janssens, G. P. J., Dec 2012, In: Journal of Animal Physiology and Animal Nutrition (Online). 96, 6, p. 1054-64 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The role of postprandial releases of insulin and incretin hormones in meal-induced satiety - effect of obesity and weight reduction
Verdich, C., Toubro, S., Buemann, B. & Holst, Jens Juul, 2001, In: International Journal of Obesity. 25, p. 1206-1214Research output: Contribution to journal › Journal article › Research › peer-review
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Gastric emptying, glucose metabolism and gut hormones: evaluation of a common preoperative carbohydrate beverage
Vermeulen, M. A. R., Richir, M. C., Garretsen, M. K., van Schie, A., Ghatei, M. A., Holst, Jens Juul, Heijboer, A. C., Uitdehaag, B. M. J., Diamant, M., Eekhoff, E. M. W., van Leeuwen, P. A. M. & Ligthart-Melis, G. C., Sep 2011, In: Nutrition. 27, 9, p. 897-903 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Acute effects of ghrelin administration on glucose and lipid metabolism.
Vestergaard, E. T., Djurhuus, C. B., Gjedsted, J., Nielsen, S., Møller, N., Holst, Jens Juul, Jørgensen, J. O. L. & Schmitz, O., 2007, In: Journal of Clinical Endocrinology and Metabolism. 93, 2, p. 438-444 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Acipimox Acutely Increases GLP-1 Concentrations in Overweight Subjects and Hypopituitary Patients
Vestergaard, E. T., Hjelholt, A. J., Kuhre, Rune Ehrenreich, Møller, N., Larraufie, P., Gribble, F. M., Reimann, F., Jessen, N., Holst, Jens Juul & Jørgensen, J. O. L., 2019, In: The Journal of clinical endocrinology and metabolism. 104, 7, p. 2581-2592Research output: Contribution to journal › Journal article › Research › peer-review
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Acute ketosis inhibits appetite and decreases plasma concentrations of acyl ghrelin in healthy humans
Vestergaard, E. T., Zubanovic, N. B., Rittig, N., Møller, N., Kuhre, Rune Ehrenreich, Holst, Jens Juul, Rehfeld, Jens Frederik & Thomsen, H. H., 2021, In: Diabetes, Obesity and Metabolism. 23, 8, p. 1834-1842Research output: Contribution to journal › Journal article › Research › peer-review
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Short-term treatment with olanzapine does not modulate gut hormone secretion: olanzapine disintegrating versus standard tablets
Vidarsdottir, S., Roelfsema, F., Streefland, T., Holst, Jens Juul, Rehfeld, Jens Frederik & Pijl, H., 2009, In: European Journal of Endocrinology. 162, 1, p. 75-83 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Statin therapy is associated with lower prevalence of gut microbiota dysbiosis
Vieira-Silva, S., Falony, G., Belda, E., Nielsen, T., Aron-Wisnewsky, J., Chakaroun, R., Forslund, S. K., Assmann, K., Valles-Colomer, M., Nguyen, T. T. D., Proost, S., Prifti, E., Tremaroli, V., Pons, N., Le Chatelier, E., Andreelli, F., Bastard, J-P., Coelho, L. P., Galleron, N., Hansen, T. H. & 28 others, , 2020, In: Nature. 581, 7808, p. 310-315Research output: Contribution to journal › Journal article › Research › peer-review
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Increased glucose-stimulated FGF21 response to oral glucose in obese non-diabetic subjects after Roux-en-Y Gastric Bypass
Vienberg, S. G., Jacobsen, S. H., Worm, D., Hvolris, L. E., Naver, L. P. S., Almdal, Thomas Peter, Hansen, D. L., Wulff, B. S., Clausen, T. R., Madsbad, Sten, Holst, Jens Juul & Andersen, B., Jan 2017, In: Clinical Endocrinology. 86, 1, p. 156-159 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Incretins, insulin secretion and type 2 diabetes mellitus
Vilsboll, T. & Holst, Jens Juul, 2004, In: Diabetologia. 47, p. 654-662Research output: Contribution to journal › Journal article › Research › peer-review
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Incretins, insulin secretion and Type 2 diabetes mellitus
Vilsbøll, T. & Holst, Jens Juul, Mar 2004, In: Diabetologia. 47, 3, p. 357-66 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Similar elimination rates of glucagon-like peptide-1 in obese type 2 diabetic patients and healthy subjects
Vilsbøll, T., Agersø, H., Krarup, T. & Holst, Jens Juul, Jan 2003, In: The Journal of clinical endocrinology and metabolism. 88, 1, p. 220-4 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Incretin secretion in relation to meal size and body weight in healthy subjects and people with type 1 and type 2 diabetes mellitus
Vilsbøll, T., Krarup, T., Sonne, J., Madsbad, Sten, Vølund, A., Juul, A. G. & Holst, Jens Juul, Jun 2003, In: The Journal of clinical endocrinology and metabolism. 88, 6, p. 2706-13 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Incretin secretion in relation to meal size and body weight in healthy subjects and in people with type 1 and type 2 diabetes mellitus
Vilsbøll, T., Krarup, T., Sonne, J., Madsbad, S., Vølund, A., Juul, A. G. & Holst, Jens Juul, 2003, In: J. Clin. Endocrinol. Metab.. 88, p. 2706-2713Research output: Contribution to journal › Journal article › Research › peer-review
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The pathogenesis of diabetes involves a defective amplication of the late phase insulin response to glucose by GIP - regardless of aetiology and phenotype
Vilsbøll, T., Knop, F., Krarup, T., Johansen, A., Madsbad, S., Larsen, S., Hansen, T., Pedersen, O. & Holst, Jens Juul, 2003, In: J. Clin. Endocrinol. Metab.. 88, p. 4897-4903Research output: Contribution to journal › Journal article › Research › peer-review
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Similar elimination rates of GLP-1 in obese type 2 diabetic patients and matched healthy subjects
Vilsbøll, T., Krarup, T., Agersø, H. & Holst, Jens Juul, 2003, In: J. Clin. Endocrinol. Metab.. 88, p. 220-224Research output: Contribution to journal › Journal article › Research › peer-review
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Both GLP-1 and GIP are insulinotropic at basal and postprandial glucose levels and contribute nearly equally to the incretin effect of a meal in healthy subjects
Vilsbøll, T., Krarup, T., Madsbad, Sten & Holst, Jens Juul, 15 Jul 2003, In: Regulatory Peptides. 114, 2-3, p. 115-21 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Incretin hormones and diabetes mellitus
Vilsbøll, Tina, Knop, Filip Krag, Deacon, Carolyn F. & Holst, Jens Juul, 2009, Therapeutic Strategies in Diabetes. Stehouwer, C. D. A. & Schaper, N. (eds.). Oxford: Clinical Publishing, p. 99-114Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
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No reactive hypoglycaemia in type 2 diabetic patients after subcutaneous administration of GLP-1 and intravenous glucose
Vilsbøll, Tina, Krarup, T., Madsbad, Sten & Holst, Jens Juul, 1 Feb 2001, In: Diabetic Medicine. 18, 2, p. 144-149 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The spectrum of antidiabetic actions of GLP-1 in patients with diabetes
Vilsbøll, Tina, Holst, Jens Juul & Knop, Filip Krag, 2009, In: Best Practice & Research: Clinical Endocrinology & Metabolism. 23, 4, p. 453-62 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The elimination rates of intact GIP as well as its primary metabolite, GIP 3-42, are similar in type 2 diabetic patients and healthy subjects.
Vilsbøll, Tina, Agersø, H., Lauritsen, T., Deacon, Carolyn F., Aaboe, K., Madsbad, Sten, Krarup, T. & Holst, Jens Juul, 2006, In: Regulatory Peptides. 137, 3, p. 168-72 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Inkretiner
Vilsbøll, Tina & Holst, Jens Juul, 2011, Diabetes - sygdom, behandling og organisation. Hilsted, J., Borch-Johnsen, K. & Christiansen, J. S. (eds.). 2 ed. København: Munksgaard , p. 67-74 8 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication
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Evaluation of ß-cell secretory capacity using glucagon-like peptide-1
Visbøll, T., Toft-Nielsen, M., Krarup, T., Madsbad, S., Dinesen, B. & Holst, Jens Juul, 2000, In: Diabetes Care. 23, p. 807-812Research output: Contribution to journal › Journal article › Research › peer-review
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Increased Insulin Secretion and Glucose Effectiveness in Obese Patients with Type 2 Diabetes following Bariatric Surgery
Visentin, R., Brodersen, K., Richelsen, B., Møller, N., Dalla Man, C., Pedersen, A. K., Abrahamsen, J., Holst, Jens Juul & Nielsen, M. F., 2023, In: Journal of Diabetes Research. 2023, 14 p., 127426.Research output: Contribution to journal › Journal article › Research › peer-review
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Exercise-induced increase in muscle insulin sensitivity in men is amplified when assessed using a meal test
Voldstedlund, Christian T, Sjøberg, K. A., Schlabs, Farina Leonie, Sigvardsen, Casper Møller, Andersen, Nicoline Resen, Holst, Jens Juul, Hartmann, Bolette, Wojtaszewski, Jørgen F P, Kiens, Bente, McConell, G. K. & Richter, Erik A., 2024, In: Diabetologia. 67, p. 1386–1398Research output: Contribution to journal › Journal article › Research › peer-review
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Predictors of incretin concentrations in subjects with normal, impaired, and diabetic glucose tolerance
Vollmer, K., Holst, Jens Juul, Baher, B., Ellrichmann, M., Nauck, M. A., Schmidt, W. E. & Meier, J. J., 2008, In: Diabetes. 57, 3, p. 678-687 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Hyperglycemia acutely lowers the postprandial excursions of glucagon-like Peptide-1 and gastric inhibitory polypeptide in humans
Vollmer, K., Gardiwal, H., Menge, B. A., Goetze, O., Deacon, Carolyn F., Schmidt, W. E., Holst, Jens Juul & Meier, J. J., 2009, In: Journal of Clinical Endocrinology and Metabolism. 94, 4, p. 1379-85 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Impact of oral vancomycin on gut microbiota, bile acid metabolism, and insulin sensitivity
Vrieze, A., Out, C., Fuentes, S., Jonker, L., Reuling, I., Kootte, R. S., van Nood, E., Holleman, F., Knaapen, M., Romijn, J. A., Soeters, M. R., Blaak, E. E., Dallinga-Thie, G. M., Reijnders, D., Ackermans, M. T., Serlie, M. J., Knop, F. K., Holst, J. J., van der Ley, C., Kema, I. P. & 6 others, , Apr 2014, In: Journal of Hepatology. 60, 4, p. 824-31 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The rate of intestinal glucose absorption is correlated with plasma glucose-dependent insulinotropic polypeptide concentrations in healthy men
Wachters-Hagedoorn, R. E., Priebe, M. G., Heimweg, J. A. J., Heiner, A. M., Englyst, K. N., Holst, Jens Juul, Stellaard, F. & Vonk, R. J., 2006, In: Journal of Nutrition. 136, 6, p. 1511-1516 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The rate of intestinal glucose absorption is correlated with plasma glucose-dependent insulinotropic polypeptide concentrations in healthy men
Wachters-Hagedoorn, R. E., Priebe, M. G., Heimweg, J. A. J., Heiner, A. M., Englyst, K. N., Holst, Jens Juul, Stellaard, F. & Vonk, R. J., Jun 2006, In: Journal of Nutrition. 136, 6, p. 1511-6 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Physiological and pharmacological mechanisms through which the DPP-4 inhibitor sitagliptin regulates glycemia in mice
Waget, A., Cabou, C., Masseboeuf, M., Cattan, P., Armanet, M., Karaca, M., Castel, J., Garret, C., Payros, G., Maida, A., Sulpice, T., Holst, Jens Juul, Drucker, D. J., Magnan, C. & Burcelin, R., Aug 2011, In: Endocrinology. 152, 8, p. 3018-3029 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Androgen receptor and nutrient signaling pathways coordinate the demand for increased amino acid transport during prostate cancer progression
Wang, Q., Bailey, C. G., Ng, C., Tiffen, J., Thoeng, A., Minhas, V., Lehman, M. L., Hendy, S. C., Buchanan, G., Nelson, C. C., Rasko, J. E. J., Holst, J. & Holst, Jens Juul, 2011, In: Cancer Research. 71, 24, p. 7525-7536 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Glucagon-like peptide-1 secretion in people with versus without type 2 diabetes: a systematic review and meta-analysis of cross-sectional studies
Watkins, J. D., Carter, S., Atkinson, G., Koumanov, F., Betts, J. A., Holst, Jens Juul & Gonzalez, J. T., 2023, In: Metabolism. 140, 11 p., 155375.Research output: Contribution to journal › Journal article › Research › peer-review
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Effects of carbohydrate restriction on body weight and glycemic control in individuals with type 2 diabetes: A randomized controlled trial of efficacy in real-life settings
Weber, P., Thomsen, M. N., fbg982, fbg982, Samkani, A., Carl, M. H., Astrup, A., Frystyk, J., Holst, Jens Juul, Hartmann, Bolette, Madsbad, Sten, Magkos, Faidon, Krarup, T. & Haugaard, Steen Bendix, 2022, In: Nutrients. 14, 24, 12 p., 5244.Research output: Contribution to journal › Journal article › Research › peer-review
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Impact of cereal fibre on glucose-regulating factors
Weickert, M. O., Mohlig, M., Koebnick, C., Holst, Jens Juul, Namsolleck, P., Ristow, M., Osterhoff, M., Rochlitz, H., Rudovich, N., Spranger, J. & Pfeiffer, A. F. H., Nov 2005, In: Diabetologia. 48, 11, p. 2343-53 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Impact of cereal fibre on glucose regulating factors
Weickert, M. O., Moehlig, M., Koebnick, C., Holst, Jens Juul, Namsolleck, P., Ristow, M., Osterhoff, M., Rochlitz, H., Rudovich, N., Spranger, J. & Pleiffer, A. F. H., 2005, In: Diabetologia. 48, p. 2343-2353Research output: Contribution to journal › Journal article › Research
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Wheat-fibre-induced changes of postprandial peptide YY and ghrelin responses are not associated with acute alterations of satiety
Weickert, M. O., Spranger, J., Holst, Jens Juul, Otto, B., Koebnick, C., Moehlig, M. & Pfeiffer, A. F. H., 2006, In: British Journal of Nutrition. 96, 5, p. 795-798 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Wheat-fibre-induced changes of postprandial peptide YY and ghrelin responses are not associated with acute alterations of satiety
Weickert, M. O., Spranger, J., Holst, Jens Juul, Otto, B., Koebnick, C., Möhlig, M. & Pfeiffer, A. F. H., Nov 2006, In: The British Journal of Nutrition. 96, 5, p. 795-8 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cross-Validation of a Glucose-Insulin-Glucagon Pharmacodynamics Model for Simulation Using Data From Patients With Type 1 Diabetes
Wendt, S. L., Ranjan, A., Møller, J. K., Schmidt, S., Knudsen, C. B., Holst, Jens Juul, Madsbad, Sten, Madsen, H., Nørgaard, Kirsten & Jørgensen, J. B., 1 Nov 2017, In: Journal of Diabetes Science and Technology. 11, 6, p. 1101-1111 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Differential impact of glucose administered intravenously or orally on bone turnover markers in healthy male subjects
Westberg-Rasmussen, S., Starup-Linde, J., Hermansen, K., Holst, Jens Juul, Hartmann, Bolette, Vestergaard, P. & Gregersen, S., Apr 2017, In: Bone. 97, p. 261-266 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Glucagon-like peptide-1 7-36 amide and peptide YY from the L-cell of the ileal mucosa are potent inhibitors of vagally induced gastric acid secretion in man
Wettergren, A., Petersen, H., Ørskov, Cathrine, Christiansen, J., Sheikh, S. P. & Holst, Jens Juul, Jun 1994, In: Scandinavian Journal of Gastroenterology. 29, 6, p. 501-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The inhibitory effect of glucagon-like peptide-1 (7-36) amide on antral motility is antagonized by its N-terminally truncated primary metabolite GLP-1 (9-36) amide.
Wettergren, A., Wojdemann, M. & Holst, Jens Juul, 1998, In: Peptides. 19, p. 877-882Research output: Contribution to journal › Journal article › Research › peer-review
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Truncated GLP-1 (proglucagon 78-107-amide) inhibits gastric and pancreatic functions in man
Wettergren, A., Schjoldager, B., Mortensen, P. E., Myhre, J., Christiansen, J. & Holst, Jens Juul, 1993, In: Digestive Diseases and Sciences. Vol. 38, no. 4, p. 665-673Research output: Contribution to journal › Journal article › Research › peer-review
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Glucagon-like peptide-1 7-36amide and peptide YY have additive inhibitory effects on gastric acid secretion in man.
Wettergren, A., Maina, P., Boesby, S. & Holst, Jens Juul, 1997, In: Scandinavian Journal of Gastroenterology. 32, p. 552-555Research output: Contribution to journal › Journal article › Research › peer-review
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Amidated and non-amidated glucagon-like peptide-1 (GLP-1): non-pancreatic effects (cephalic phase acid secretion) and stability in plasma in humans
Wettergren, A., Pridal, L., Wöjdemann, M. & Holst, Jens Juul, 1998, In: Regul. Pept.. 77, p. 83-88Research output: Contribution to journal › Journal article › Research › peer-review
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Glucagon-like peptide-1 inhibits gastropancreatic function by inhibiting central parasympathetic outflow
Wettergren, A., Wojdemann, M. & Holst, Jens Juul, 1998, In: Am. J. Physiol.. 275, p. G984-G992Research output: Contribution to journal › Journal article › Research › peer-review
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The inhibitory effect of glucagon-like peptide-1 (GLP-1) 7-36 amide on gastric acid secretion in humans depends on an intact vagal innervation.
Wettergren, A., Wøjdemann, M., Meisner, S., Stadil, F. & Holst, Jens Juul, 1997, In: Gut. 40, p. 597-601Research output: Contribution to journal › Journal article › Research › peer-review
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Glucagon-like peptide-1 (GLP-1) 7-36 amide and peptide YY from L-cell in the ileal mucosa are potent inhibitors of vagally induced gastric acid secretion in man
Wettergren, A., Petersen, H., Ørskov, Cathrine, Christiansen, J., Sheikh, S. & Holst, Jens Juul, 1994, In: Scandinavian Journal of Gastroenterology. 29, p. 501-505Research output: Contribution to journal › Journal article › Research › peer-review
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Associations between ghrelin and leptin and neural food cue reactivity in a fasted and sated state
Wever, M. C. M., van Meer, F., Charbonnier, L., Crabtree, D. R., Buosi, W., Giannopoulou, A., Androutsos, O., Johnstone, A. M., Manios, Y., Meek, C. L., Holst, Jens Juul, Smeets, P. A. M. & Full4Health consortium, F. C., 2021, In: NeuroImage. 240, 11 p., 118374.Research output: Contribution to journal › Journal article › Research › peer-review
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KU bestemmer selv over sin forskning
Wewer, Ulla M., Holst, Jens Juul, Schwartz, Thue W. & Quistorff, B., 2 Jun 2011, In: Universitetsavisen.Research output: Contribution to journal › Contribution to newspaper - Comment/debate › Communication
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Acute effects on glucose tolerance by neprilysin inhibition in patients with type 2 diabetes
Albrechtsen, Nicolai Jacob Wewer, Møller, A., Martinussen, C., Gluud, Lise Lotte, Rashu, E. B., Richter, Michael Martin, Plomgaard, Peter Stendahl, Goetze, Jens P. , Kjeldsen, Sasha Alexandra Sampson, Hansen, L. H., Gustafsson, Finn, Deacon, Carolyn F., Holst, Jens Juul, Madsbad, Sten & Bojsen-Møller, K. N., 2022, In: Diabetes, Obesity and Metabolism. 24, 10, p. 2017-2026 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Oxyntomodulin Identified as a Marker of Type 2 Diabetes and Gastric Bypass Surgery by Mass-spectrometry Based Profiling of Human Plasma
Albrechtsen, Nicolai Jacob Wewer, Hornburg, D., Albrechtsen, Reidar, Svendsen, B., Toräng, S., Jepsen, Sara Lind, Kuhre, Rune Ehrenreich, Hansen, M., Janus, C., Floyd, A., Lund, Asger Bach, Vilsbøll, Tina, Knop, Filip Krag, drb459, drb459, Deacon, Carolyn F., Meissner, F., Mann, Matthias, Holst, Jens Juul & Hartmann, Bolette, May 2016, In: EBioMedicine. 7, p. 112-120 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Inability of Some Commercial Assays to Measure Suppression of Glucagon Secretion
Albrechtsen, Nicolai Jacob Wewer, Veedfald, Simon, Plamboeck, A., Deacon, Carolyn F., Hartmann, Bolette, Knop, Filip Krag, Vilsbøll, Tina & Holst, Jens Juul, 2016, In: Journal of Diabetes Research. 2016, 5 p., 8352957.Research output: Contribution to journal › Journal article › Research › peer-review
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Sacubitril/Valsartan Augments Postprandial Plasma Concentrations of Active GLP-1 When Combined With Sitagliptin in Men
Albrechtsen, Nicolai Jacob Wewer, Mark, P. D., Terzic, D., Hansen, L. H., Andersen, U. Ø., Hartmann, Bolette, Carr, R. D., Gustafsson, Finn, Deacon, Carolyn F., Holst, Jens Juul, Goetze, Jens P. & Plomgaard, Peter Stendahl, 2019, In: Journal of Clinical Endocrinology and Metabolism. 104, 9, p. 3868-3876Research output: Contribution to journal › Journal article › Research › peer-review
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The biology of glucagon and the consequences of hyperglucagonemia
Albrechtsen, Nicolai Jacob Wewer, Kuhre, Rune Ehrenreich, Pedersen, Jens, Knop, Filip Krag & Holst, Jens Juul, 9 Sep 2016, In: Biomarkers in Medicine. 10, 11, p. 1141-1151 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Evidence of a liver-alpha cell axis in humans: hepatic insulin resistance attenuates relationship between fasting plasma glucagon and glucagonotropic amino acids
Albrechtsen, Nicolai Jacob Wewer, Færch, K., Jensen, T. M., Witte, D. R., Pedersen, Jens, Mahendran, Y., Jonsson, Anna Elisabet, Galsgaard, Katrine Douglas, Winther-Sørensen, Marie, Torekov, Signe Sørensen, Lauritzen, T., Pedersen, Oluf Borbye, Knop, Filip Krag, Hansen, Torben, Jørgensen, M. E., Vistisen, D. & Holst, Jens Juul, 2018, In: Diabetologia. 61, 3, p. 671-680Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Health care professionals from developing countries report educational benefits after an online diabetes course
Albrechtsen, Nicolai Jacob Wewer, Poulsen, K. W., Svensson, L. Ø., Jensen, Lasse X, Holst, Jens Juul & Torekov, Signe Sørensen, 31 May 2017, In: B M C Medical Education. 17, 8 p., 97.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
100 years of glucagon and 100 more
Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Cherrington, A. D., Finan, B., Gluud, Lise Lotte, Dean, E. D., Campbell, J. E., Bloom, S. R., Tan, T. M., Knop, Filip Krag & Müller, T. D., 2023, In: Diabetologia. 66, p. 1378–1394Research output: Contribution to journal › Review › Research › peer-review
- Published
Hyperglucagonemia correlates with plasma levels of non-branched-chain amino acids in patients with liver disease independent of type 2 diabetes
Albrechtsen, Nicolai Jacob Wewer, Junker, A. E., Christensen, M., Hædersdal, S., Wibrand, F., Lund, A. M., Galsgaard, Katrine Douglas, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2018, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 314, 1, p. G91-G96Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A sandwich ELISA for measurement of the primary glucagon-like peptide-1 metabolite
Albrechtsen, Nicolai Jacob Wewer, Asmar, A., Jensen, F., Törang, S., Simonsen, L., Kuhre, Rune Ehrenreich, Asmar, M., Veedfald, Simon, Plamboeck, A., Knop, Filip Krag, Vilsbøll, Tina, Madsbad, Sten, Nauck, M. A., Deacon, Carolyn F., Bülow, J., Holst, Jens Juul & Hartmann, Bolette, 1 Sep 2017, In: American Journal of Physiology: Endocrinology and Metabolism. 313, 3, p. E284-E291Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The liver-alpha cell axis and type 2 diabetes
Albrechtsen, Nicolai Jacob Wewer, Pedersen, Jens, Galsgaard, Katrine Douglas, Winther-Sørensen, Marie, Suppli, M. P., Janah, L., Gromada, J., Vilstrup, H., Knop, Filip Krag & Holst, Jens Juul, 2019, In: Endocrine Reviews. 40, 5, p. 1353-1366Research output: Contribution to journal › Review › Research › peer-review
- Published
Plasma Proteome Profiling Reveals Dynamics of Inflammatory and Lipid Homeostasis Markers after Roux-En-Y Gastric Bypass Surgery
Albrechtsen, Nicolai Jacob Wewer, Geyer, P. E., Doll, S., Treit, P. V., Bojsen-Møller, K. N., Martinussen, C., Jørgensen, N. B., Torekov, Signe Sørensen, Meier, F., Niu, Lili, Santos, A., Keilhauer, E. C., Holst, Jens Juul, Madsbad, Sten & Mann, Matthias, 2018, In: Cell Systems. 7, 6, p. 601-612Research output: Contribution to journal › Journal article › Research › peer-review
- Published
On measurements of glucagon secretion in healthy, obese, and Roux-en-Y gastric bypass operated individuals using sandwich ELISA
Albrechtsen, Nicolai Jacob Wewer, Kjeldsen, Sasha Alexandra Sampson, Jensen, N. J., Rungby, Jørgen, Veedfald, Simon, Bojsen-Møller, K. N., Dirksen, C., Jensen, Christian Zinck, Martinussen, C., Madsbad, Sten & Holst, Jens Juul, 2022, In: Scandinavian Journal of Clinical & Laboratory Investigation. 82, 1, p. 75-83Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Do glucagonomas always produce glucagon?
Albrechtsen, Nicolai Jacob Wewer, Challis, B., Damjanov, I. & Holst, Jens Juul, 1 Feb 2016, In: Bosnian Journal of Basic Medical Sciences. 16, 1, p. 1-7 7 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Tirzepatide is an imbalanced and biased dual GIP and GLP-1 receptor agonist
Willard, F. S., Douros, J. D., Gabe, M., Showalter, A. D., Wainscott, D. B., Suter, T. M., Capozzi, M. E., van der Velden, W. J. C., Stutsman, C., Cardona, G. R., Urva, S., Emmerson, P. J., Holst, Jens Juul, D'Alessio, D. A., Coghlan, M. P., Rosenkilde, Mette, Campbell, J. E. & Sloop, K. W., 2020, In: JCI insight. 5, 17, 16 p., 140532.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gastric emptying, glucose responses, and insulin secretion after a liquid test meal: effects of exogenous glucagon-like peptide-1 (GLP-1)-(7-36) amide in type 2 (noninsulin-dependent) diabetic patients
Willms, B., Werner, J., Holst, Jens Juul, Ørskov, Cathrine, Creutzfeldt, W. & Nauck, M. A., Jan 1996, In: Endocrinology. 81, 1, p. 327-32 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Overnight GLP-1 normalizes fasting but not daytime plasma glucose levels in NIDDM patients
Willms, B., Idowu, K., Holst, Jens Juul, Creutzfeldt, W. & Nauck, M. A., 1998, In: Exp. Clin. Endocrinol. Diabetes. 106, p. 103-107Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Why is it so difficult to measure glucagon-like peptide-1 in a mouse?
Windeløv, Johanne Agerlin, Albrechtsen, Nicolai Jacob Wewer, Kuhre, Rune Ehrenreich, Jepsen, Sara Lind, Hornburg, D., Pedersen, Jens, Jensen, E. P., Galsgaard, Katrine Douglas, Winther-Sørensen, Marie, Ørgaard, A., Deacon, Carolyn F., Mann, Matthias, Kissow, Hannelouise, Hartmann, Bolette & Holst, Jens Juul, Oct 2017, In: Diabetologia. 60, 10, p. 2066-2075 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Use of anesthesia dramatically alters the oral glucose tolerance and insulin secretion in C57Bl/6 mice
Windeløv, Johanne Agerlin, Pedersen, Jens & Holst, Jens Juul, Jun 2016, In: Physiological Reports. 4, 11, 6 p., e12824.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hepatic steatosis and glucagon resistance develope in parallel resulting in hyperglucagonaemia and hyperaminoacidaemia
Winther-Sørensen, Marie, Galsgaard, Katrine Douglas, Santos, A., Pedersen, J., Hassing, Anna Skab, Dall, M., Treebak, Jonas Thue, Kjeldsen, Sasha Alexandra Sampson, Knop, Filip Krag, Werge, M. P., Eriksen, P. L., Vilstrup, H., Gluud, Lise Lotte, Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2020, In: Diabetologia. 63, SUPPL 1, p. S71-S72 142.Research output: Contribution to journal › Conference abstract in journal › Research
- E-pub ahead of print
Determinants of plasma levels of proglucagon and the metabolic impact of glucagon receptor signalling: a UK Biobank study
Winther-Sørensen, Marie, Garcia, S. L., Bartholdy, Andreas, Ottenheijm, Maud Eline, Banasik, Karina, Brunak, Søren, Sorensen, Charlotte Mehlin, Gluud, Lise Lotte, Knop, Filip Krag, Holst, Jens Juul, Rosenkilde, Mette, Jensen, Majken Karoline & Albrechtsen, Nicolai Jacob Wewer, 6 May 2024, (E-pub ahead of print) In: Diabetologia.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon acutely regulates hepatic amino acid catabolism and the effect may be disturbed by steatosis
Winther-Sørensen, M., Galsgaard, K. D., Santos, A., Trammell, S. A. J., Sulek, K., Kuhre, R. E., Pedersen, J., Andersen, D. B., Hassing, A. S., Dall, M., Treebak, J. T., Gillum, M. P., Torekov, S. S., Windeløv, J. A., Hunt, J. E., Kjeldsen, S. A. S., Jepsen, S. L., Vasilopoulou, C. G., Knop, F. K., Ørskov, C. & 7 others, , 2020, In: Molecular Metabolism. 42, 18 p., 101080.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hepatic Glucose Production, Ureagenesis, and Lipolysis Quantified using the Perfused Mouse Liver Model
Winther-Sørensen, Marie, Kemp, I. M., Bisgaard, Hanne Cathrine, Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2023, In: Journal of Visualized Experiments. 2023, 200, e65596.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The feedback cycles between glucose, amino acids and lipids and alpha cell secretion and their role in metabolic fatty liver disease
Winther-Sørensen, Marie, Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2023, In: Current Opinion in Lipidology. 34, 1, p. 27-31Research output: Contribution to journal › Review › Research › peer-review
- Published
Differential effect of PYY1-36 and PYY3-36 on gastric emptying in man
Witte, A., Grybäck, P., Holst, Jens Juul, Hilsted, Linda, Hellström, P. M., Jacobsson, H. & Schmidt, P. T., 2009, In: Regulatory Peptides. 158, 1-3, p. 57-62 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Involvement of endogenous glucagon-like peptide-1 in regulation of gastric motility and pancreatic endocrine secretion
Witte, A., Grybäck, P., Jacobsson, H., Näslund, E., Hellström, P. M., Holst, Jens Juul, Hilsted, Linda & Schmidt, P. T., 2011, In: Scandinavian Journal of Gastroenterology. Supplement. 46, 4, p. 428-35 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Peptide YY3-36 and glucagon-like peptide-1 in functional dyspepsia. Secretion and role in symptom generation
Witte, A., Hilsted, Linda, Holst, Jens Juul & Schmidt, P. T., Apr 2016, In: Scandinavian Journal of Gastroenterology. 51, 4, p. 400-409 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-2 inhibits centrally induced antral motility in pigs
Wojdemann, M., Wettergren, A., Hartmann, B. & Holst, Jens Juul, 1998, In: Scandinavian Journal of Gastroenterology. 33, p. 828-832Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibition of human gastric lipase secretion by glucagon-like peptide-1
Wojdemann, M., Wettergren, A., Sternby, B., Holst, Jens Juul, Larsen, S., Rehfeld, J. F. & Olsen, O., 1998, In: Dig. Dis. Sci.. 43, p. 799-805Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gastric emptying of solutions containing the natural sweetener erythritol and effects on gut hormone secretion in humans: A pilot dose-ranging study
Wolnerhanssen, B. K., Drewe, J., Verbeure, W., le Roux, C. W., Dellatorre-Teixeira, L., Rehfeld, Jens Frederik, Holst, Jens Juul, Hartmann, Bolette, Tack, J., Peterli, R., Beglinger, C. & Meyer-Gerspach, A. C., 2021, In: Diabetes, Obesity and Metabolism. 23, 6, p. 1311-1321Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Measurement of plasma glucagon in humans: A shift in the performance of a current commercially available radioimmunoassay kit
Wu, T., Rayner, C. K., Jones, K. L., Horowitz, M., Feinle-Bisset, C., Standfield, S. D., Xie, C., Deacon, Carolyn F., Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2022, In: Diabetes, Obesity and Metabolism. 24, 6, p. 1182-1184Research output: Contribution to journal › Letter › Research › peer-review
- Published
Human gastric lipase secretion is inhibited by intraduodenal perfusion of dietary fat.
Wøjdemann, M., Riber, C., Bisgaard, T., Sternby, B., Larsen, S., Rehfeld, J. F., Holst, Jens Juul & Olesen, O., 1999, In: Regulatory Peptides. 80, p. 101-106Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibition of shamfeeding stimulated human gastric acid secretion by glucagon-like peptide-2
Wøjdemann, M., Wettergren, A., Hartmann, B., Hilsted, L. M. & Holst, Jens Juul, 1999, In: J. Clin. Endocrinol. Metab.. 84, p. 2513-2517Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glutamate prevents intestinal atrophy via luminal nutrient sensing in a mouse model of total parenteral nutrition
Xiao, W., Feng, Y., Holst, Jens Juul, Hartmann, Bolette, Yang, H. & Teitelbaum, D. H., May 2014, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 28, 5, p. 2073-87 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In the rat pancreas, somatostatin tonically inhibits glucagon secretion and is required for glucose-induced inhibition of glucagon secretion
Xu, S. F. S., Andersen, Daniel Bjørklund, Izarzugaza, J. M. G., Kuhre, Rune Ehrenreich & Holst, Jens Juul, 2020, In: Acta Physiologica. 229, 3, 15 p., e13464.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Little enhancement of meal-induced GLP-1 secretion in Japanese: Comparison of type 2 diabetes and healthy controls
Yabe, D., Kuroe, A., Lee, S., Watanabe, K., Hyo, T., Hishizawa, M., Kurose, T., Deacon, Carolyn F., Holst, Jens Juul, Hirano, T., Inagaki, N. & Seino, Y., Jan 2010, In: Journal of Diabetes Investigation. 1, 1/2, p. 56-59Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Little enhancement of meal-induced glucagon-like peptide 1 secretion in Japanese: Comparison of type 2 diabetes patients and healthy controls
Yabe, D., Kuroe, A., Lee, S., Watanabe, K., Hyo, T., Hishizawa, M., Kurose, T., Deacon, Carolyn F., Holst, Jens Juul, Hirano, T., Inagaki, N. & Seino, Y., 22 Apr 2010, In: Journal of Diabetes Investigation. 1, 1-2, p. 56-9 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Early phase glucagon and insulin secretory abnormalities, but not incretin secretion, are similarly responsible for hyperglycemia after ingestion of nutrients
Yabe, D., Kuroe, A., Watanabe, K., Iwasaki, M., Hamasaki, A., Hamamoto, Y., Harada, N., Yamane, S., Lee, S., Murotani, K., Deacon, Carolyn F., Holst, Jens Juul, Hirano, T., Inagaki, N., Kurose, T. & Seino, Y., 2015, In: Journal of Diabetes and its Complications. 29, p. 413-421 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dipeptidyl peptidase expression during experimental colitis in mice
Yazbeck, R., Sulda, M. L., Howarth, G. S., Bleich, A., Raber, K., von Hörsten, S., Holst, Jens Juul & Abbott, C. A., 1 Aug 2010, In: Inflammatory Bowel Diseases. 16, 8, p. 1340-1351 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Preserved glucagon-like peptide-1 responses to oral glucose, but reduced incretin effect, insulin secretion and sensitivity in young Asians with type 2 diabetes mellitus
Yeow, T. P., Pacini, G., Tura, A., Hor, C. P., Lim, S. L., Tan, F. H. S., Tong, C. V., Hong, J. Y. H., Md Zain, F., Holst, Jens Juul & Wan Mohamud, W. N., 2017, In: BMJ open diabetes research & care. 5, 1, 9 p., e000352.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of Gastric Bypass and Gastric Banding on Bone Remodeling in Obese Patients with Type 2 Diabetes
Yu, E. W., Wewalka, M., Ding, S., Simonson, D. C., Foster, K., Holst, Jens Juul, Vernon, A., Goldfine, A. B. & Halperin, F., Feb 2016, In: Journal of Clinical Endocrinology and Metabolism. 101, 2, p. 714–722Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The metabolite generated by dipeptidyl-peptidase 4 metabolism of glucagon-like peptide-1 has no influence on plasma glucose levels in patients with type 2 diabetes
Zander, M., Madsbad, Sten, Deacon, Carolyn F. & Holst, Jens Juul, Feb 2006, In: Diabetologia. 49, 2, p. 369-74 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Additive glucose-lowering effects of glucagon-like peptide- 1 and metformin type 2 diabetes
Zander, M., Taskiran, M., Toft-Nielsen, M. B. & Holst, Jens Juul, 2001, In: Diabetes Care. 24, p. 720-725Research output: Contribution to journal › Journal article › Research › peer-review
ID: 4207
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Meal induced gut hormone secretion is altered in aerobically trained compared to sedentary young healthy males
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Copenhagen study of overweight patients with coronary artery disease undergoing low energy diet or interval training: the randomized CUT-IT trial protocol
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Whole grain-rich diet reduces body weight and systemic low-grade inflammation without inducing major changes of the gut microbiome: a randomised cross-over trial
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