Thomas Svava Nielsen

Thomas Svava Nielsen

Research consultant


  1. 2010
  2. Reduced cannabinoid receptor 1 protein in subcutaneous adipose tissue of obese

    Bennetzen, M. F., Nielsen, Thomas Svava, Paulsen, S. K., Bendix, J., Fisker, S., Jessen, N., Lund, S., Richelsen, B. & Pedersen, S. B., Feb 2010, In: European Journal of Clinical Investigation. 40, 2, p. 121-6 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Effects of GH in human muscle and fat

    Jørgensen, J. O. L., Rubeck, K. Z., Nielsen, Thomas Svava, Clasen, B. F. F., Vendelboe, M., Hafstrøm, T. K., Madsen, M. & Lund, S., Apr 2010, In: Pediatric nephrology (Berlin, Germany). 25, 4, p. 705-9 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. 2011
  5. GLUT4 and UBC9 protein expression is reduced in muscle from type 2 diabetic patients with severe insulin resistance

    Kampmann, U., Christensen, B., Nielsen, Thomas Svava, Pedersen, S. B., Ørskov, L., Lund, S., Møller, N. & Jessen, N., 2011, In: PLOS ONE. 6, 11, p. e27854

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Fasting, but not exercise, increases adipose triglyceride lipase (ATGL) protein and reduces G(0)/G(1) switch gene 2 (G0S2) protein and mRNA content in human adipose tissue

    Nielsen, Thomas Svava, Vendelbo, M., Jessen, N., Pedersen, S. B., Jørgensen, J. O. L., Lund, S. & Møller, N., Aug 2011, In: The Journal of clinical endocrinology and metabolism. 96, 8, p. E1293-7

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. 2012
  8. Published

    Evaluation of functional erythropoietin receptor status in skeletal muscle in vivo: acute and prolonged studies in healthy human subjects

    Christensen, B., Lundby, C., Jessen, N., Nielsen, Thomas Svava, Vestergaard, P. F., Møller, N., Pilegaard, Henriette, Pedersen, S. B., Kopchick, J. J. & Jørgensen, J. O. L., 2012, In: P L o S One. 7, 2, 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Insulin resistance after a 72-h fast is associated with impaired AS160 phosphorylation and accumulation of lipid and glycogen in human skeletal muscle

    Vendelbo, M., Clasen, B. F. F., Treebak, Jonas Thue, Møller, L., Krusenstjerna-Hafstrøm, T., Madsen, M., Nielsen, Thomas Svava, Stødkilde-Jørgensen, H., Pedersen, S. B., Jørgensen, J. O. L., Goodyear, L. J., Wojtaszewski, Jørgen F P, Møller, N. & Jessen, N., 2012, In: American Journal of Physiology: Endocrinology and Metabolism. 302, 2, p. E190-E200 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Reduced mRNA and protein expression of perilipin A and G0/G1 switch gene 2 (G0S2) in human adipose tissue in poorly controlled type 2 diabetes

    Nielsen, Thomas Svava, Kampmann, U., Nielsen, R. R., Jessen, N., Orskov, L., Pedersen, S. B., Jørgensen, J. O. L., Lund, S. & Møller, N., Jul 2012, In: The Journal of clinical endocrinology and metabolism. 97, 7, p. E1348-52

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. 2014
  12. Published

    A common Greenlandic TBC1D4 variant confers muscle insulin resistance and type 2 diabetes

    Moltke, I., Grarup, N., Jørgensen, M. E., Bjerregaard, P., Treebak, J. T., Fumagalli, M., Korneliussen, T. S., Andersen, M. A., Nielsen, T. S., Krarup, N. T., Gjesing, A. M. P., Zierath, J. R., Linneberg, A., Wu, X., Sun, G., Jin, X., Al-Aama, J., Wang, J., Borch-Johnsen, K., Pedersen, O. & 3 others, Nielsen, R., Albrechtsen, Anders & Hansen, Torben, 2014, In: Nature. 512, 7513, p. 190-193 4 p.

    Research output: Contribution to journalLetterResearchpeer-review

  13. Published

    Growth hormone-induced insulin resistance in human subjects involves reduced pyruvate dehydrogenase activity

    Nellemann, B., Vendelbo, M. H., Nielsen, Thomas Svava, Bak, A. M., Høgild, M., Pedersen, S. B., Biensø, R. S., Pilegaard, Henriette, Møller, N., Jessen, N. & Jørgensen, J. O. L., 2014, In: Acta Physiologica. 210, 2, p. 392-402 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Adipose triglyceride lipase and g0/g1 switch gene 2: approaching proof of concept

    Nielsen, Thomas Svava & Møller, N., Mar 2014, In: Diabetes. 63, 3, p. 847-9 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Dissecting adipose tissue lipolysis: molecular regulation and implications for metabolic disease

    Nielsen, Thomas Svava, Jessen, N., Jørgensen, J. O. L., Møller, N. & Lund, S., Jun 2014, In: Journal of Molecular Endocrinology. 52, 3, p. R199-R222 24 p.

    Research output: Contribution to journalReviewResearchpeer-review

  16. 2015
  17. Published

    Intact Pituitary Function is Decisive for the Catabolic Response to TNF-α: Studies of Protein, Glucose and Fatty Acid Metabolism in Hypopituitary and Healthy Subjects

    Bach, E., Møller, A. B., Jørgensen, J. O. L., Vendelbo, M. H., Jessen, N., Olesen, J. F., Pedersen, S. B., Nielsen, Thomas Svava & Møller, N., Feb 2015, In: The Journal of clinical endocrinology and metabolism. 100, 2, p. 578-86 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. 2016
  19. Published

    Dietary fat drives whole-body insulin resistance and promotes intestinal inflammation independent of body weight gain

    Jensen, Benjamin Anderschou Holbech, Nielsen, Thomas Svava, Fritzen, Andreas Mæchel, Holm, J. B., Fjære, E., Serup, A. K. L., Borkowski, K., Risis, S., Pærregaard, S. I., Søgaard, I., Poupeau, A. A. G., Poulsen, M., Ma, Tao, Sina, C., Kiens, Bente, Madsen, L., Kristiansen, Karsten & Treebak, Jonas Thue, 2016, In: Metabolism. 65, 12, p. 1706-1719 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Regulation of Lipolysis and Adipose Tissue Signaling during Acute Endotoxin-Induced Inflammation: A Human Randomized Crossover Trial

    Rittig, N., Bach, E., Thomsen, H. H., Pedersen, S. B., Nielsen, Thomas Svava, Jørgensen, J. O., Jessen, N. & Møller, N., 2016, In: P L o S One. 11, 9, p. 1-13 13 p., e0162167.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Pronounced expression of the lipolytic inhibitor G0/G1 Switch Gene 2 (G0S2) in adipose tissue from brown bears (Ursus arctos) prior to hibernation

    Jessen, N., Nielsen, Thomas Svava, Vendelbo, M. H., Viggers, R., Støen, O., Evans, A. & Frøbert, O., Apr 2016, In: Physiological Reports. 4, 8, p. 1-7 7 p., e12781.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Combined insulin deficiency and endotoxin exposure stimulate lipid mobilization and alter adipose tissue signaling in an experimental model of ketoacidosis in subjects with type 1 diabetes: A randomized, controlled, cross over trial

    Svart, M., Kampmann, U., Voss, T., Pedersen, S. B., Johannsen, M., Rittig, N., Poulsen, P. L., Nielsen, Thomas Svava, Jessen, N. & Møller, N., May 2016, In: Diabetes. 65, 5, p. 1380-6 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Differential regulation of lipid and protein metabolism in obese vs. lean subjects before and after a 72-h fast

    Bak, A. M., Møller, A. B., Vendelbo, M. H., Nielsen, Thomas Svava, Viggers, R., Rungby, Jørgen, Pedersen, S. B., Jørgensen, J. O. L., Jessen, N. & Møller, N., 1 Jul 2016, In: American Journal of Physiology: Endocrinology and Metabolism. 311, 1, p. E224-35 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Stress hormone release is a key component of the metabolic response to lipopolysaccharide (LPS): studies in hypopituitary and healthy subjects

    Bach, E., Møller, A. B., Jorgensen, J. O. L., Vendelbo, M. H., Jessen, N., Pedersen, S. B., Nielsen, Thomas Svava & Møller, N., 25 Aug 2016, In: European Journal of Endocrinology. 175, 5, p. 455-465 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. 2017
  26. Published

    Effects of insulin-induced hypoglycaemia on lipolysis rate, lipid oxidation and adipose tissue signalling in human volunteers: a randomised clinical study

    Voss, T. S., Vendelbo, M. H., Kampmann, U., Pedersen, S. B., Nielsen, Thomas Svava, Johannsen, M., Svart, M. V., Jessen, N. & Møller, N., Jan 2017, In: Diabetologia. 60, 1, p. 143-52 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. 2018
  28. Published

    Sevoflurane Impairs Insulin Secretion and Tissue-Specific Glucose Uptake In Vivo

    Høyer, K. F., Nielsen, Thomas Svava, Risis, S., Treebak, Jonas Thue & Jessen, N., 2018, In: Basic & Clinical Pharmacology & Toxicology. 123, 6, p. 732-738

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Skeletal muscle O-GlcNAc transferase is important for muscle energy homeostasis and whole-body insulin sensitivity

    Shi, H., Munk, A., Nielsen, T. S., Daughtry, M. R., Larsson, L., Li, S., Høyer, K. F., Geisler, H. W., Sulek, K., Kjøbsted, R., Fisher, T., Andersen, M. M., Shen, Z., Hansen, U. K., England, E. M., Cheng, Z., Højlund, K., Wojtaszewski, J., Yang, X., Hulver, M. W. & 3 others, Helm, R. F., Treebak, Jonas Thue & Gerrard, D. E., 2018, In: Molecular Metabolism. 11, p. 160-177 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. 2019
  31. Published

    Aerobic and resistance exercise training reverses age-dependent decline in NAD(+) salvage capacity in human skeletal muscle

    de Guia, R. M., Agerholm, M., Nielsen, Thomas Svava, Consitt, L. A., Sogaard, D., Helge, Jørn Wulff, Larsen, Steen, Brandauer, J., Houmard, J. A. & Treebak, Jonas Thue, 2019, In: Physiological Reports. 7, 12, 15 p., e14139.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Assessment of mouse liver [1-13C]pyruvate metabolism by dynamic hyperpolarized MRS

    Faarkrog Høyer, K., Laustsen, C., Ringgaard, S., Qi, H., Mariager, C. Ø., Nielsen, Thomas Svava, Sundekilde, U. K., Treebak, Jonas Thue, Jessen, N. & Stødkilde-Jørgensen, H., 2019, In: Journal of Endocrinology. 242, 3, p. 251-260 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Effects of short-term prednisolone treatment on indices of lipolysis and lipase signaling in abdominal adipose tissue in healthy humans

    Ramshanker, N., Jessen, N., Voss, T. S., Pedersen, S. B., Jørgensen, J. O. L., Nielsen, Thomas Svava, Frystyk, J. & Møller, N., 2019, In: Metabolism: Clinical and Experimental. 99, p. 1-10

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Electrical pulse stimulation induces differential responses in insulin action in myotubes from severely obese individuals

    Park, S., Turner, K. D., Zheng, D., Brault, J. J., Zou, K., Chaves, A. B., Nielsen, Thomas Svava, Tanner, C. J., Treebak, Jonas Thue & Houmard, J. A., 2019, In: The Journal of Physiology. 597, 2, p. 449-466

    Research output: Contribution to journalJournal articleResearchpeer-review

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