Jens Juul Holst
Professor
Endocrinology and Metabolism
Blegdamsvej 3
2200 København N.
- 2003
- Published
Absence of a memory effect for the insulinotropic action of glucagon-like peptide 1(GLP-1) in healthy volunteers
Meier, S., Hücking, K., Ritzelt, R., Holst, Jens Juul, Schmiegel, W. H. & Nauck, M. A., 2003, In: Horm Metab Res. 35, p. 551-556Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of GLP-1 effects on beta cell function after meal ingestion in humans
Ahren, B., Holst, Jens Juul & Mari, A., 2003, In: Diabetes Care. 26, p. 2860-2864Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Circulating leptin and thyroid dysfunction.
Zimmermann-Belsing, T., Brabant, G., Holst, Jens Juul & Feldt-Rasmussen, Ulla, 2003, In: European Journal of Endocrinology. 149, 4, p. 257-71 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cocaine and amphetamine-regulated transcript (CART) is present in hypothalamic neuroendocrine neurons and is related to the hypothalamo-pituitary portal circuit
Larsen, P. J., Seier, V., Fink-Jensen, A., Holst, Jens Juul, Warberg, J. & Vrang, N., 2003, In: Journal of Neuroendocrinology. 15, p. 219-226Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Colonic fermentation influences lower esophageal sphincter function in gastroesophageal reflux disease.
Piche, T., des Varannes, S. B., Sacher-Huvelin, S., Holst, Jens Juul, Cuber, J. C. & Galmiche, J. P., 2003, In: Gastroenterology. 124, 4, p. 894-902 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparisons of leptin, incretins and body composition in obese and lean patients with hypopituitarism and healthy individuals
Mersebach, H., Svendsen, Ole Lander, Holst, Jens Juul, Astrup, A. & Feldt-Rasmussen, Ulla, 2003, In: Clinical Endocrinology. 58, 1, p. 65-71 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differential effects of saturated and monounsaturated fat on postprandial lipemia and incretin responses in type 2 diabetic subjects
Thomsen, C., Storm, H., Holst, Jens Juul & Hermansen, K., 2003, In: Am. J. Clin. Nutr.. 77, p. 605-611Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differential regional metabolism of glucagon in anesthetized pigs.
Deacon, Carolyn F., Kelstrup, M., Trebbien, R., Klarskov, L., Olesen, M. & Holst, Jens Juul, 2003, In: American Journal of Physiology: Endocrinology and Metabolism. 285, 3, p. E552-60Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Does overnight normalization of plasma glucose by insulin infusion affect assessment of glucose metabolism in type 2 diabetes
Staehr, P., Højlund, K., Hother-Nielsen, O., Holst, Jens Juul & Beck-Nielsen, H., 2003, In: Diabetic Medicine. 20, p. 816-822Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of GLP-2 treatment and antibiotics on gut structure and function during pig weanling diarrhea
Nielsen, T. T., Sangild, Per Torp, Elnif, J., Sorensen, K., Leser, T., Holst, Jens Juul, Hartmann, B., Jensen, B. B. & Hedemann, M. S., 2003, Ikke angivet. R.O. Ball (ed.). 2 ed. University of Alberta Press, p. 161-163 3 p.Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research
- Published
Effects of free fatty acids per se on glucose production, gluconeogenesis, and glycogenolysis.
Staehr, P., Hother-Nielsen, O., Landau, B. R., Chandramouli, V., Holst, Jens Juul & Beck-Nielsen, H., 2003, In: Diabetes. 52, 2, p. 260-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Et æble om dagen
Larsen, P. J., Holst, Jens Juul & Astrup, A., 2003, In: Politiken. 29, 2 p.Research output: Contribution to journal › Contribution to newspaper - Feature article › Communication
- Published
Exogenous GLP-2 has only marginal effects on weaning-induced intestinal adaption in piglets
le Huërou-Luron, I., Petersen, Y. M., Hartmann, B., Holst, Jens Juul & Sangild, Per Torp, 2003, Ikke angivet. R.O. Ball (ed.). 2 ed. University of Alberta Press, p. 164-166 3 p.Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research
- Published
Functional and immunohistochemical evaluation of porcine neonatal islet-like cell clusters.
Nielsen, T. B., Yderstraede, K. B., Schrøder, H. D., Holst, Jens Juul, Brusgaard, K. & Beck-Nielsen, H., 2003, In: Cell Transplantation. 12, 1, p. 13-25 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-1 and GIP are colocalized in a subset of endocrine cells in the small intestine
Mortensen, K., Christensen, L. L., Holst, Jens Juul & Ørskov, Cathrine, 2003, In: Regulatory Peptides. 114, 2-3, p. 189-96 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-2 mediated up-regulation of intestinal blood flow and glucose uptake is nitric oxide-dependent in TNP-fed piglets
Guan, X., Stoll, B., Lu, X., Tappenden, K., Holst, Jens Juul, Hartmann, B. & Burrin, D. G., 2003, In: Today in Medicine. Gastroenterology. 125, p. 136-147Research output: Contribution to journal › Journal article › Research
- Published
Gastric inhibitory polypeptide (GIP) does not inhibit gastric emptying in man
Meier, J. M., Goetze, O., Anstipp, J., Hagemann, D., Holst, Jens Juul, Schmidt, W. E., Gallwitz, B. & Nauck, M. A., 2003, In: Am. J. Physiol.. 16, p. E621-E625Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gastric inhibitory polypeptide (GIP) dose-dependently stimulates glucagon secretion in healthy human subjects at euglycaemia
Meier, J. J., Gallwitz, N., Siepmann, N., Holst, Jens Juul, Deacon, Carolyn F., Schmidt, W. E. & Nauck, M. A., 2003, In: Diabetologia. 46, p. 798-801Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impaired intestinal proglucagon processing in mice lacking prohormone convertase 1.
Ugleholdt, Randi Kjærsgaard, Zhu, X., Deacon, Carolyn F., Ørskov, Cathrine, Steiner, D. F. & Holst, Jens Juul, 2003, In: Endocrinology. 145, 3, p. 1349-55 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Implementation of GLP-1 based therapy of type 2 diabetes mellitus using DPP-IV inhibitors.
Holst, Jens Juul, 2003, In: Advances in Experimental Medicine and Biology. 524, p. 263-79 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Incretin secretion in relation to meal size and body weight in healthy subjects and in people with type 1 and type 2 diabetes mellitus
Vilsbøll, T., Krarup, T., Sonne, J., Madsbad, S., Vølund, A., Juul, A. G. & Holst, Jens Juul, 2003, In: J. Clin. Endocrinol. Metab.. 88, p. 2706-2713Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Insulin secretion and cellular glucose metabolism after prolonged low-grade intralipid infusion in young men
Jensen, C. B., Storgaard, H., Holst, Jens Juul, Dela, F., Madsbad, Sten & Vaag, A. A., 2003, In: Journal of Clinical Endocrinology and Metabolism. 88, 6, p. 2775-2783 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Introduction of enteral food increases plasma GLP-2 and decreases GLP-2 receptor mRNA abundance during pig development
Petersen, Y. M., Hartmann, B., Holst, Jens Juul, Le Huërou-Luron, I., Bjørnvad, Charlotte Reinhard & Sangild, Per Torp, 2003, In: Journal of Nutrition. 133, 6, p. 1781-1786 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lower blood glucose, hyperglucagonemia and pancreatic alpha cell hyperplasia in glucagon receptor knockout mice
Gelling, R. W., Du, X. Q., Dichmann, D. S., Rømer, J., Huan, H., Cui, L., Tang, B. L., Holst, Jens Juul, Fledelius, C., Johansen, P. B., Jelicks, L. A., Serup, P., Nishimura, E. & Charron, M. J., 2003, In: Proc Natl Sci. 100, p. 1438-1443Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lower glucose-dependent insulinotropic polypeptide (GIP) response but similar glucagon-like peptide 1 (GLP-1), glycaemic, and insulinaemic response to ancient wheat compared to modern wheat depends on processing
Bakhøj, S., Flint, A., Holst, Jens Juul & Tetens, Inge , 2003, In: European Journal of Clinical Nutrition. 57, 10, p. 1254-1261 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Meals with similar energy densities but rich in protein, fat, carbohydrate, or alcohol have different effects on energy expenditure and substrate metabolism but not on appetite and energy intake
Raben, A. B., Agerholm-Larsen, L., Flint, A., Holst, Jens Juul & Astrup, A., 2003, In: American Journal of Clinical Nutrition. 77, 1, p. 91-100 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
NO has tonic inhibitory, but is not involved in the vagal control or VIP effects on motility of the porcine antrum
Schmidt, P. T., Ørskov, C., Rasmussen, T. N. & Holst, Jens Juul, 2003, In: Scandinavian Journal of Gastroenterology. 38, p. 955-961Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Neutral endopeptidase 24.11 and dipeptidyl peptidase IV are both involved in regulating the metabolic stability of glucagon-like peptide-1 in vivo.
Plamboeck, A., Holst, Jens Juul, Carr, R. D. & Deacon, Carolyn F., 2003, In: Advances in Experimental Medicine and Biology. 524, p. 303-12 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
No effect of physiological concentrations of glucagon-like peptide-2 on appetite and energy intake in normal weight subjects
Sørensen, L. B., Flint, A., Raben, A. B., Hartmann, B., Holst, Jens Juul & Astrup, A., 2003, In: International Journal of Obesity. 27, 4, p. 450-456 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
No reactive hypoglycaemia after subcutaneous administrations of GLP-1 in lean type 2 diabetic patients and in patients with diabeties secondary to chronic pancreatitis
Knop, F., Vilsbøll, T., Larsen, S., Holst, Jens Juul & Krarup, T., 2003, In: Diabetes Care. 26, p. 2581-2587Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Normalisation of glucose concentrations and deceleration of gastric emptying of solid meals during intravenous glucagon-like peptide-1 (GLP-1) in patients with type 2 diabetes
Meier, J. J., Gallwitz, B., Salmen, S., Goetze, O., Holst, Jens Juul & Schmidt, W. E., 2003, In: J. Clin. Endocrinol. Metab.. 88, p. 2719-2725Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Peripheral administration of GLP-2 to humans has no effect on gastric emptying or satiety
Schmidt, P. T., Näslund, E., Grybäck, P., Jacobsson, H., Hartmann, B., Holst, Jens Juul & Hellström, P. M., 2003, In: Regul. Pept.. 116, p. 21-25Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prediction of glycemic index in mixed meals
Møller, B. K., Flint, A., Pedersen, D., Raben, A. B., Tetens, I., Holst, Jens Juul & Astrup, A., 2003. 1 p.Research output: Contribution to conference › Paper › Research
- Published
Role of luminal nutrients and endogenous GLP-2 in intestinal adaptation to mid small bowel resection
Dahly, E. M., Gillingham, M. B., Guo, Z., Murali, S. G., Nelson, D. W., Holst, Jens Juul & Ney, D. M., 2003, In: Amer. J. Physiol.. 284, p. G670-G682Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Similar elimination rates of GLP-1 in obese type 2 diabetic patients and matched healthy subjects
Vilsbøll, T., Krarup, T., Agersø, H. & Holst, Jens Juul, 2003, In: J. Clin. Endocrinol. Metab.. 88, p. 220-224Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Similar insulin secretory response to a gastric inhibitory polypeptide bolus injection at euglycemia in first-degree relatives of patients with type 2 diabetes and control subjects.
Meier, J. J., Nauck, M. A., Siepmann, N., Greulich, M., Holst, Jens Juul, Deacon, Carolyn F., Schmidt, W. E. & Gallwitz, B., 2003, In: Metabolism - Clinical and Experimental. 52, 12, p. 1579-85 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Small intestinal dysfunction accompanies the complex endocrinopathy of human proprotein convertase 1 deficiency
Jackson, R. S., Creemers, J. W. M., Saraf Faraoqi, I., Raffin-Sanson, M. L., Varro, A., Dockray, G. J., Holst, J. J., Brubaker, P. L., Corvol, P., Polonsky, K. S., Ostrega, D., Becker, K. L., Bertagna, X., Hutton, J. C., White, A., Dattani, M. T., Hussain, K., Middleton, S. J., Nicholl, T. M., Lindley, K. J. & 1 others, , 2003, In: J. Clin. Invest.. 112, p. 1550-1560Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Somatostatin receptors.
Møller, L. N., Stidsen, C. E., Hartmann, B. & Holst, Jens Juul, 2003, In: BBA General Subjects. 1616, 1, p. 1-84 83 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structural differences between rye and wheat bread but not total fiber content may explain the lower postprandial insulin response to rye bread
Juntunen, K. S., Laaksonen, D. E., Aitio, K., Niskanen, L. K., Holst, Jens Juul, Savolainen, K. E., Liukkonen, K. H., Poutanen, K. S. & Mykkänen, H. M., 2003, In: Am. J. Clin. Nutr.. 78, p. 957-964Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The influence of GLP-1 on glucose-induced insulin secretion: effect on ß-cells sensitivity in type 2 and non-diabetic subjects
Kjems, L. L., Holst, Jens Juul, Vølund, A. A. & Madsbad, S., 2003, In: Diabetes. 52, p. 380-386Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The pathogenesis of diabetes involves a defective amplication of the late phase insulin response to glucose by GIP - regardless of aetiology and phenotype
Vilsbøll, T., Knop, F., Krarup, T., Johansen, A., Madsbad, S., Larsen, S., Hansen, T., Pedersen, O. & Holst, Jens Juul, 2003, In: J. Clin. Endocrinol. Metab.. 88, p. 4897-4903Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The reduction in hepatic insulin clearance after oral glucose is not mediated by gastric inhibitory polypeptide (GIP).
Meier, J. J., Gallwitz, B., Siepmann, N., Holst, Jens Juul, Deacon, Carolyn F., Schmidt, W. E. & Nauck, M. A., 2003, In: Regulatory Peptides. 113, 1-3, p. 95-100 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Will GLP-1 treatment increase blood pressure? Summary and comment
Holst, Jens Juul, 2003, In: Diabetes Monitor. 15, p. 15-17Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Similar elimination rates of glucagon-like peptide-1 in obese type 2 diabetic patients and healthy subjects
Vilsbøll, T., Agersø, H., Krarup, T. & Holst, Jens Juul, Jan 2003, In: The Journal of clinical endocrinology and metabolism. 88, 1, p. 220-4 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The influence of GLP-1 on glucose-stimulated insulin secretion: effects on beta-cell sensitivity in type 2 and nondiabetic subjects
Kjems, L. L., Holst, Jens Juul, Vølund, A. & Madsbad, Sten, Feb 2003, In: Diabetes. 52, 2, p. 380-6 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cocaine- and amphetamine-regulated transcript is present in hypothalamic neuroendocrine neurones and is released to the hypothalamic-pituitary portal circuit
Larsen, P. J., Seier, V., Fink-Jensen, Anders, Holst, Jens Juul, Warberg, J. & Vrang, N., Mar 2003, In: Journal of Neuroendocrinology. 15, 3, p. 219-26 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differential effects of saturated and monounsaturated fats on postprandial lipemia and glucagon-like peptide 1 responses in patients with type 2 diabetes
Thomsen, C., Storm, H., Holst, Jens Juul & Hermansen, K., Mar 2003, In: Uden navn. 77, 3, p. 605-11 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
No effect of physiological concentrations of glucagon-like peptide-2 on appetite and energy intake in normal weight subjects
Sørensen, L. B., Flint, A., Raben, Anne, Hartmann, Bolette, Holst, Jens Juul & Astrup, A., Apr 2003, In: International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity. 27, 4, p. 450-6 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Role of luminal nutrients and endogenous GLP-2 in intestinal adaptation to mid-small bowel resection
Dahly, E. M., Gillingham, M. B., Guo, Z., Murali, S. G., Nelson, D. W., Holst, Jens Juul & Ney, D. M., Apr 2003, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 284, 4, p. G670-82Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gastric inhibitory polypeptide (GIP) dose-dependently stimulates glucagon secretion in healthy human subjects at euglycaemia
Meier, J. J., Gallwitz, B., Siepmann, N., Holst, Jens Juul, Deacon, Carolyn F., Schmidt, W. E. & Nauck, M. A., Jun 2003, In: Diabetologia. 46, 6, p. 798-801 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Meal induced gut hormone secretion is altered in aerobically trained compared to sedentary young healthy males
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Copenhagen study of overweight patients with coronary artery disease undergoing low energy diet or interval training: the randomized CUT-IT trial protocol
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Whole grain-rich diet reduces body weight and systemic low-grade inflammation without inducing major changes of the gut microbiome: a randomised cross-over trial
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