Thue W. Schwartz

Thue W. Schwartz

Professor

Member of:

    ORCID: 0000-0002-0261-6904

    Publication year:
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    101 - 125 out of 259Page size: 25
    1. 2006
    2. Published

      Activation of the CXCR3 chemokine receptor through anchoring of a small molecule chelator ligand between TM-III, -IV, and -VI

      Rosenkilde, Mette, Andersen, Michael Brun, Nygaard, R., Frimurer, T. M. & Schwartz, Thue W., 2006, In: Molecular Pharmacology. 71, 3, p. 930-41 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      Ago-allosteric modulation and other types of allostery in dimeric 7TM receptors

      Schwartz, Thue W. & Holst, Birgitte, 2006, In: Journal of Receptors and Signal Transduction. 26, 1-2, p. 107-28 21 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      Conformational constraining of inactive and active States of a seven transmembrane receptor by metal ion site engineering in the extracellular end of transmembrane segment V

      Rosenkilde, Mette, David, R., Oerlecke, I., Benned-Jensen, T., Geumann, U., Beck-Sickinger, A. G. & Schwartz, Thue W., 2006, In: Molecular Pharmacology. 70, 6, p. 1892-901 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      GPR39 signaling is stimulated by zinc ions but not by obestatin

      Holst, Birgitte, Egerod, Kristoffer Lihme, Schild, E., Vickers, S. P., Cheetham, S., Gerlach, L., Storjohann, L., Stidsen, C. E., Jones, R., Beck-Sickinger, A. G. & Schwartz, Thue W., 2006, In: Endocrinology. 148, 1, p. 13-20 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      Ghrelin receptor inverse agonists: identification of an active peptide core and its interaction epitopes on the receptor

      Holst, Birgitte, Lang, M., Brandt, E., Bach, Anders, Howard, A., Frimurer, T. M., Beck-Sickinger, A. & Schwartz, Thue W., 2006, In: Molecular Pharmacology. 70, 3, p. 936-46 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      Ghrelin receptor mutations--too little height and too much hunger

      Holst, Birgitte & Schwartz, Thue W., 2006, In: Journal of Clinical Investigation. 116, 3, p. 637-41 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      GluVII : 06 - a highly conserved and selective anchor point for non-peptide ligands in chemokine receptors

      Rosenkilde, Mette & Schwartz, Thue W., 2006, In: Current Topics in Medicinal Chemistry. 6, 13, p. 1319-1333 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      GluVII:06--a highly conserved and selective anchor point for non-peptide ligands in chemokine receptors

      Rosenkilde, Mette & Schwartz, Thue W., 2006, In: Current Topics in Medicinal Chemistry. 6, 13, p. 1319-33 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Metal ion site engineering indicates a global toggle switch model for seven-transmembrane receptor activation

      Elling, C. E., Frimurer, T. M., Gerlach, L., Jorgensen, R., Holst, Birgitte & Schwartz, Thue W., 2006, In: Journal of Biological Chemistry. 281, 25, p. 17337-46 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Molecular mechanism of 7TM receptor activation--a global toggle switch model

      Schwartz, Thue W., Frimurer, T. M., Holst, Birgitte, Rosenkilde, Mette & Elling, C. E., 2006, In: Annual Review of Pharmacology and Toxicology. 46, p. 481-519 38 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Molecular pharmacological phenotyping of EBI2. An orphan seven-transmembrane receptor with constitutive activity

      Rosenkilde, Mette, Benned-Jensen, T., Holst, Peter Johannes, Kledal, T. N., Lüttichau, H. R., Larsen, J. K., Christensen, Jan Pravsgaard, Schwartz, Thue W. & Andersen, H., 2006, In: Journal of Biological Chemistry. 281, 19, p. 13199-208 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      The PP-fold solution structure of human polypeptide YY and human PYY3-36 as determined by NMR

      Nygaard, R., Nielbo, S., Schwartz, Thue W. & Poulsen, F. M., 2006, In: Biochemistry. 45, 27, p. 8350-7 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. 2007
    15. Published

      Allosteric enhancers, allosteric agonists and ago-allosteric modulators: where do they bind and how do they act?

      Schwartz, Thue W. & Holst, Birgitte, 2007, In: TIPS - Trends in Pharmacological Sciences. 28, 8, p. 366-73 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Characterization of G-protein coupled receptor kinase interaction with the neurokinin-1 receptor using bioluminescence resonance energy transfer

      Jorgensen, R., Holliday, N. D., Hansen, J. L., Vrecl, M., Heding, A., Schwartz, Thue W. & Elling, C. E., 2007, In: Molecular Pharmacology. 73, 2, p. 349-58 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      GPR39 splice variants versus antisense gene LYPD1: expression and regulation in gastrointestinal tract, endocrine pancreas, liver, and white adipose tissue.

      Egerod, Kristoffer Lihme, Holst, Birgitte, Petersen, P. S., Hansen, Jacob B., Mulder, J., Hökfelt, T. & Schwartz, Thue W., 2007, In: Molecular Endocrinology. 21, 7, p. 1685-98 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      Identification of an efficacy switch region in the ghrelin receptor responsible for interchange between agonism and inverse agonism

      Holst, Birgitte, Mokrosinski, J., Lang, M., Brandt, E., Nygaard, R., Frimurer, T. M., Beck-Sickinger, A. G. & Schwartz, Thue W., 2007, In: Journal of Biological Chemistry. 282, 21, p. 15799-811 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      Importance of constitutive activity and arrestin-independent mechanisms for intracellular trafficking of the ghrelin receptor

      Holliday, N. D., Holst, Birgitte, Rodionova, E. A., Schwartz, Thue W. & Cox, H. M., 2007, In: Molecular Endocrinology. 21, 12, p. 3100-12 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      Kaposi sarcoma-associated herpes virus targets the lymphotactin receptor with both a broad spectrum antagonist vCCL2 and a highly selective and potent agonist vCCL3

      Lüttichau, H. R., Johnsen, A. H., Jurlander, J., Rosenkilde, Mette & Schwartz, Thue W., 2007, In: Journal of Biological Chemistry. 282, 24, p. 17794-805 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      Modest human immunodeficiency virus coreceptor function of CXCR3 is strongly enhanced by mimicking the CXCR4 ligand binding pocket in the CXCR3 receptor

      Hatse, S., Huskens, D., Princen, K., Vermeire, K., Bridger, G. J., De Clercq, E., Rosenkilde, Mette, Schwartz, Thue W. & Schols, D., 2007, In: Journal of Virology. 81, 7, p. 3632-9 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      Molecular interaction of a potent nonpeptide agonist with the chemokine receptor CCR8

      Jensen, P. C., Nygaard, R., Thiele, S., Elder, A., Zhu, G., Kolbeck, R., Ghosh, S., Schwartz, Thue W. & Rosenkilde, Mette, 2007, In: Molecular Pharmacology. 72, 2, p. 327-40 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Molecular mechanism of action of monocyclam versus bicyclam non-peptide antagonists in the CXCR4 chemokine receptor

      Rosenkilde, Mette, Gerlach, L., Hatse, S., Skerlj, R. T., Schols, D., Bridger, G. J. & Schwartz, Thue W., 2007, In: Journal of Biological Chemistry. 282, 37, p. 27354-65 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      Oxyntomodulin differentially affects glucagon-like peptide-1 receptor beta-arrestin recruitment and signaling through Galpha(s)

      Jorgensen, R., Kubale, V., Vrecl, M., Schwartz, Thue W. & Elling, C. E., 2007, In: Journal of Pharmacology and Experimental Therapeutics. 322, 1, p. 148-54 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. 2008
    26. Published

      A gut feeling for obesity: 7TM sensors on enteroendocrine cells

      Engelstoft, M. S., Egerod, Kristoffer Lihme, Holst, Birgitte & Schwartz, Thue W., 2008, In: Cell Metabolism. 8, 6, p. 447-9 2 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    27. Published

      A second disulfide bridge from the N-terminal domain to extracellular loop 2 dampens receptor activity in GPR39

      Storjohann, L., Holst, Birgitte & Schwartz, Thue W., 2008, In: Biochemistry. 47, 35, p. 9198-207 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    28. Published

      Characterization of G-protein coupled receptor kinase interaction with the NK-1 receptor using BRET

      Joergensen, R., Holliday, N. D., Hansen, J. L., Vrecl, M., Heding, A., Elling, C. E. & Schwartz, Thue W., 2008, In: Molecular Pharmaceutics. 73, 2, p. 349-358 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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    ID: 11601