Jens Juul Holst

Jens Juul Holst

Professor

ORCID: 0000-0001-6853-3805

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  1. Published

    Liraglutide improves the beta-cell function without increasing insulin secretion during a mixed meal in patients, who exhibit well-controlled type 2 diabetes and coronary artery disease

    Anholm, C., Kumarathurai, P., Jurs, A., Pedersen, L. R., Nielsen, Olav Wendelboe, Kristiansen, O. P., Fenger, M., Holst, Jens Juul, Madsbad, Sten, Sajadieh, Ahmad & Haugaard, Steen Bendix, 2019, In: Diabetology & Metabolic Syndrome. 11, 12 p., 42.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Liraglutide preserved insulin secretion in adults with newly diagnosed type 1 diabetes: the NewLira trial: [Meeting Abstract}

    Dejgaard, T. F., Frandsen, C., Kielgast, U., Andersen, H. U., Thorsteinsson, B., Krarup, T., Holst, Jens Juul & Madsbad, Sten, 2019, In: Diabetologia. 62, Supl. 1/SI, p. S75-S75 145.

    Research output: Contribution to journal › Conference abstract in journal › Research

  3. Published

    Liraglutide treatment for the prevention of glucose tolerance deterioration in women with prior gestational diabetes mellitus: A 52-week randomized controlled clinical trial

    Foghsgaard, S., Vedtofte, L., Andersen, E. S., Bahne, E., Andreasen, C., Sørensen, A. L., Forman, Julie Lyng, Mathiesen, Elisabeth, Svare, J. A., Clausen, Tine Dalsgaard, Damm, Peter, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2023, In: Diabetes, Obesity and Metabolism. 26, 1, p. 201-214 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Liraglutide-Induced Weight Loss May be Affected by Autonomic Regulation in Type 1 Diabetes

    Hansen, C. S., Frandsen, C. S., Fleischer, J., Vistisen, D., Holst, Jens Juul, Tarnow, L., Knop, Filip Krag, Madsbad, Sten, Andersen, H. U. & Dejgaard, T. F., 2019, In: Frontiers in Endocrinology. 10, 9 p., 242.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Little enhancement of meal-induced GLP-1 secretion in Japanese: Comparison of type 2 diabetes and healthy controls

    Yabe, D., Kuroe, A., Lee, S., Watanabe, K., Hyo, T., Hishizawa, M., Kurose, T., Deacon, Carolyn F., Holst, Jens Juul, Hirano, T., Inagaki, N. & Seino, Y., Jan 2010, In: Journal of Diabetes Investigation. 1, 1/2, p. 56-59

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Little enhancement of meal-induced glucagon-like peptide 1 secretion in Japanese: Comparison of type 2 diabetes patients and healthy controls

    Yabe, D., Kuroe, A., Lee, S., Watanabe, K., Hyo, T., Hishizawa, M., Kurose, T., Deacon, Carolyn F., Holst, Jens Juul, Hirano, T., Inagaki, N. & Seino, Y., 22 Apr 2010, In: Journal of Diabetes Investigation. 1, 1-2, p. 56-9 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Lixisenatide for type 2 diabetes mellitus

    Christensen, M., Knop, Filip Krag, Vilsbøll, Tina & Holst, Jens Juul, 2011, In: Expert Opinion on Investigational Drugs. 20, 4, p. 549-57 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Lixisenatide in type 1 diabetes: A randomised control trial of the effect of lixisenatide on post-meal glucose excursions and glucagon in type 1 diabetes patients

    Ballav, C., Dhere, A., Kennedy, I., Agbaje, O. F., White, S., Franklin, R., Hartmann, Bolette, Holst, Jens Juul, Holman, R. R. & Owen, K. R., 2020, In: Endocrinology, Diabetes and Metabolism. 3, 3, 9 p., e00130.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Lixisenatide, a novel GLP-1 receptor agonist for the treatment of type 2 diabetes mellitus

    Christensen, M., Knop, Filip Krag, Holst, Jens Juul & Vilsboll, T., 2009, In: IDrugs. The Investigational Drugs Journal. 12, 8, p. 503-13 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Localisation and neural control of the release of calcitonin gene-related peptide (CGRP) from the isolated perfused porcine ileum

    Rasmussen, T. N., Schmidt, P., Poulsen, S. S., Holst, Jens Juul & Poulsen, Steen Seier, 20 Apr 2001, In: Regulatory Peptides. 98, 3, p. 137-143 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Localization in the gastrointestinal tract of immunoreactive prosomatostatin

    Holst, Jens Juul & Poulsen, Steen Seier, Nov 1987, In: Regulatory Peptides. 19, 3-4, p. 183-95 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Long-acting agonists of human and rodent GLP-2 receptors for studies of the physiology and pharmacological potential of the GLP-2 system

    Gadgaard, S., Windeløv, Johanne Agerlin, Schiellerup, S. P., Holst, Jens Juul, Hartmann, Bolette & Rosenkilde, Mette, 2023, In: Biomedicine and Pharmacotherapy. 160, 13 p., 114383.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Long-acting glucagon-like peptide-1 receptor agonist-status December 2018

    Holst, Jens Juul, 2019, In: Annals of Translational Medicine. 7, 5, 6 p., 83 .

    Research output: Contribution to journal › Editorial › Research

  14. Published

    Long-term effects of bariatric surgery on meal disposal and β-cell function in diabetic and nondiabetic patients

    Camastra, S., Muscelli, E., Gastaldelli, A., Holst, Jens Juul, Astiarraga, B., Baldi, S., Nannipieri, M., Ciociaro, D., Anselmino, M., Mari, A. & Ferrannini, E., Nov 2013, In: Diabetes. 62, 11, p. 3709-17 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Long-term exendin-4 treatment delays natural deterioration of glycaemic control in diabetic Goto-Kakizaki rats

    Simonsen, L., Pilgaard, S., Orskov, C., Hartmann, Bolette, Holst, Jens Juul & Deacon, Carolyn F., 2009, In: Diabetes, Obesity and Metabolism. 11, 9, p. 884-90 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Long-term inhibition of dipeptidyl peptidase IV improves glucose tolerance and preserves islet function in mice

    Reimer, M. K., Holst, Jens Juul & Ahrén, B., 2002, In: European Journal of Endocrinology. 146, p. 717-727

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Long-term inhibition of dipeptidyl peptidase IV improves glucose tolerance and preserves islet function in mice

    Reimer, M. K., Holst, Jens Juul & Ahrén, B., May 2002, In: European Journal of Endocrinology. Supplement. 146, 5, p. 717-27 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Long-term outcomes of dietary carbohydrate restriction for HbA1c reduction in type 2 diabetes mellitus are needed. Reply to Kang J and Ma E [letter]

    Thomsen, M. N., Astrup, A., Holst, Jens Juul, Madsbad, Sten, Magkos, Faidon, Haugaard, Steen Bendix & Krarup, T., 2022, In: Diabetologia. 65, 6, p. 1060-1062 3 p.

    Research output: Contribution to journal › Comment/debate › Research

  19. Published

    Loss of Incretin Effect Is a Specific, Important, and Early Characteristic of Type 2 Diabetes

    Holst, Jens Juul, Knop, Filip Krag, Vilsbøll, Tina, Krarup, T. & Madsbad, Sten, May 2011, In: Diabetes Care. 34, Supplement 2, p. S251-7 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Loss of inverse relationship between pulsatile insulin and glucagon secretion in patients with type 2 diabetes

    Menge, B. A., Grüber, L., Jørgensen, S. M., Deacon, Carolyn F., Schmidt, W. E., Veldhuis, J. D., Holst, Jens Juul & Meier, J. J., Aug 2011, In: Diabetes. 60, 8, p. 2160-2168 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Loss of the Secretin Receptor Impairs Renal Bicarbonate Excretion and Aggravates Metabolic Alkalosis in Mice during Acute Base-Loading

    Berg, P., Jensen, T., Andersen, J. F., Svendsen, S. L., Modvig, Ida Marie, Wang, T., Frische, S., Chow, B. K. C., Malte, H., Holst, Jens Juul, Sørensen, M. V. & Leipziger, J., 2023, In: Journal of the American Society of Nephrology : JASN. 34, 8, p. 1329-1342 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Low-Carbohydrate Diet Impairs the Effect of Glucagon in the Treatment of Insulin-Induced Mild Hypoglycemia: A Randomized Crossover Study

    Ranjan, A., Schmidt, S., Damm-Frydenberg, C., Steineck, I., Clausen, T. R., Holst, Jens Juul, Madsbad, Sten & Nørgaard, Kirsten, Jan 2017, In: Diabetes Care. 40, 1, p. 132-135 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Lower blood glucose, hyperglucagonemia and pancreatic alpha cell hyperplasia in glucagon receptor knockout mice

    Gelling, R. W., Du, X. Q., Dichmann, D. S., Rømer, J., Huan, H., Cui, L., Tang, B. L., Holst, Jens Juul, Fledelius, C., Johansen, P. B., Jelicks, L. A., Serup, P., Nishimura, E. & Charron, M. J., 2003, In: Proc Natl Sci. 100, p. 1438-1443

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Lower glucose-dependent insulinotropic polypeptide (GIP) response but similar glucagon-like peptide 1 (GLP-1), glycaemic, and insulinaemic response to ancient wheat compared to modern wheat depends on processing

    Bakhøj, S., Flint, A., Holst, Jens Juul & Tetens, Inge , 2003, In: European Journal of Clinical Nutrition. 57, 10, p. 1254-1261 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Lower-body fat mass as an independent marker of insulin sensitivity - the role of adiponectin?

    Buemann, B., Black, E., Sørensen, Thorkild I.A., Holst, C., Toubro, S., Pedersen, O., Holst, Jens Juul, Rasmussen, C. & Astrup, A., 2005, In: International Journal of Obesity. 29, p. 624-631

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    MODERATE EXERCISE DOES NOT IMPAIR THE EFFECT OF GLUCAGON IN INSULIN PUMP TREATED INDIVIDUALS WITH TYPE 1 DIABETES: A RANDOMIZED CROSSOVER STUDY: [Meeting Abstract}

    Steineck, I., Ranjan, A., Schmidt, S., Holst, Jens Juul & Norgaard, K., 2018, In: Diabetes Technology & Therapeutics. 20, p. A35-A35 072.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  27. Published

    Major rapid weight loss induces changes in cardiac repolarization

    Vedel-Larsen, E., Iepsen, E. P. W., Lundgren, J., Graff, C., Struijk, J. J., Hansen, Torben, Holst, Jens Juul, Madsbad, Sten, Torekov, Signe Sørensen & Kanters, Jørgen K., 10 Feb 2016, In: Journal of Electrocardiology. 49, 3, p. 467-472 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Markers of Glucagon Resistance Improve With Reductions in Hepatic Steatosis and Body Weight in Type 2 Diabetes

    Kjeldsen, Sasha Alexandra Sampson, Thomsen, M. N., Skytte, M. J., Samkani, A., Richter, Michael Martin, Frystyk, J., Magkos, Faidon, Hansen, E., Thomsen, Henrik S., Holst, Jens Juul, Madsbad, Sten, Haugaard, Steen Bendix, Krarup, T. & Albrechtsen, Nicolai Jacob Wewer, 2023, In: Journal of the Endocrine Society. 7, 11, 11 p., bvad122.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Mathematical Modelling of Glucose-Dependent Insulinotropic Polypeptide and Glucagon-like Peptide-1 following Ingestion of Glucose

    Røge, R. M., Bagger, J. I., Alskär, O., Kristensen, N. R., Klim, S., Holst, Jens Juul, Ingwersen, S. H., Karlsson, M. O., Knop, Filip Krag, Vilsbøll, Tina & Kjellsson, M. C., Oct 2017, In: Basic & Clinical Pharmacology & Toxicology. 121, 4, p. 290-297 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Meal induced gut hormone secretion is altered in aerobically trained compared to sedentary young healthy males

    Lund, M. T., Taudorf, L., Hartmann, Bolette, Helge, Jørn Wulff, Holst, Jens Juul & Dela, Flemming, 1 Nov 2013, In: European Journal of Applied Physiology. 113, 11, p. 2737-47 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Meal-induced compositional changes in blood and saliva in persons with bulimia nervosa

    Dynesen, A. W., Jensen, A. B., Astrup, A., Petersson, B., Holst, Jens Juul & Nauntofte, B., 2008, In: American Journal of Clinical Nutrition. 87, 1, p. 12-22 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Meal-stimulated glucagon release is associated with postprandial blood glucose level and does not interfere with glycemic control in children and adolescents with new-onset type 1 diabetes

    Porksen, S., Nielsen, L. B., Kaas, A., Kocova, M., Chiarelli, F., Orskov, C., Holst, Jens Juul, Ploug, K. B., Hougaard, P. P., Hansen, L. & Mortensen, H. B., 2007, In: Journal of Clinical Endocrinology and Metabolism. 92, 8, p. 2910-2916 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Meal-stimulated glucagon release is associated with postprandial blood glucose level and does not interfere with glycemic control in children and adolescents with new-onset type 1 diabetes

    Pörksen, S., Nielsen, L. B., Kaas, A., Kocova, M., Chiarelli, F., Ørskov, Cathrine, Holst, Jens Juul, Ploug, K. B., Hougaard, P., Hansen, L. & Mortensen, H. B., Aug 2007, In: The Journal of clinical endocrinology and metabolism. 92, 8, p. 2910-6 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Meals with similar energy densities but rich in protein, fat, carbohydrate, or alcohol have different effects on energy expenditure and substrate metabolism but not on appetite and energy intake

    Raben, A. B., Agerholm-Larsen, L., Flint, A., Holst, Jens Juul & Astrup, A., 2003, In: American Journal of Clinical Nutrition. 77, 1, p. 91-100 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Measurement of plasma glucagon in humans: A shift in the performance of a current commercially available radioimmunoassay kit

    Wu, T., Rayner, C. K., Jones, K. L., Horowitz, M., Feinle-Bisset, C., Standfield, S. D., Xie, C., Deacon, Carolyn F., Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2022, In: Diabetes, Obesity and Metabolism. 24, 6, p. 1182-1184

    Research output: Contribution to journal › Letter › Research › peer-review

  36. Published

    Measurement of the incretin hormones: glucagon-like peptide-1 and glucose-dependent insulinotropic peptide

    Kuhre, Rune Ehrenreich, Albrechtsen, Nicolai Jacob Wewer, Hartmann, Bolette, Deacon, Carolyn F. & Holst, Jens Juul, Apr 2015, In: Journal of Diabetes and its Complications. 29, 3, p. 445-450 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Measurements Inhibition of DPP-4 evokes pancreatic and extra-pancreatic mechanisms that improve glucose homeostasis in type 2 diabetes mellitus.

    Azuma, K., Radikova, Z., Mancino, J., Toledo, F., Thomas, E., Kangani, C., Dalla Man, C., Cobelli, C., Holst, Jens Juul, Deacon, Carolyn F., He, Y., Ligueros-Saylan, M., Serra, D. & Kelley, D., 2008, In: Journal of Clinical Endocrinology and Metabolism. 93, p. 459-463

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Measurements of islet function and glucose metabolism with the dipeptidyl peptidase 4 inhibitor vildagliptin in patients with type 2 diabetes

    Azuma, K., Rádiková, Z., Mancino, J., Toledo, F. G. S., Thomas, E., Kangani, C., Dalla Man, C., Cobelli, C., Holst, Jens Juul, Deacon, Carolyn F., He, Y., Ligueros-Saylan, M., Serra, D., Foley, J. E. & Kelley, D. E., 2007, In: Journal of Clinical Endocrinology and Metabolism. 93, 2, p. 459-464 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Mechanism-based population modelling for assessment of L-cell function based on total GLP-1 response following an oral glucose tolerance test

    Møller, J. B., Jusko, W. J., Gao, W., Hansen, Torben, Pedersen, Oluf Borbye, Holst, Jens Juul, Overgaard, R. V., Madsen, H. & Ingwersen, S. H., 2011, In: Journal of Pharmacokinetics and Pharmacodynamics. 38, 6, p. 713-25 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Mechanisms Underlying Gut Hormone Secretion Using the Isolated Perfused Rat Small Intestine

    Kuhre, Rune Ehrenreich & Holst, Jens Juul, 2019, In: Journal of Visualized Experiments. 144, e58533.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Mechanisms behind the superior effects of interval vs continuous training on glycaemic control in individuals with type 2 diabetes: a randomised controlled trial

    Karstoft, K., Winding, K., Knudsen, S. H., James, N. G., Scheel, M. M., Olesen, J., Holst, Jens Juul, Pedersen, Bente Klarlund & Solomon, T., 2014, In: Diabetologia. 57, 10, p. 2081-2093 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Mechanisms for the antihyperglycemic effect of sitagliptin in patients with type 2 diabetes

    Muscelli, E., Casolaro, A., Gastaldelli, A., Mari, A., Seghieri, G., Astiarraga, B., Chen, Y., Alba, M., Holst, Jens Juul & Ferrannini, E., Aug 2012, In: Journal of Clinical Endocrinology and Metabolism. 97, 8, p. 2818-26 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Mechanisms in bariatric surgery: Gut hormones, diabetes resolution, and weight loss

    Holst, Jens Juul, Madsbad, Sten, Bojsen-Møller, K. N., Svane, M. S., Jørgensen, N. B., Dirksen, C. & Martinussen, C., May 2018, In: Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery. 14, 5, p. 708-714 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Mechanisms of Gastric Emptying Disturbances in Chronic and Acute Inflammation of the Distal Gastrointestinal Tract

    Keller, J., Beglinger, C., Holst, Jens Juul, Andresen, V. & Layer, P., 2009, In: American Journal of Physiology: Gastrointestinal and Liver Physiology.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Mechanisms of action of a carbohydrate-reduced, high-protein diet in reducing the risk of postprandial hypoglycemia after Roux-en-Y gastric bypass surgery

    Kandel, D., Bojsen-Møller, K. N., Svane, M. S., Samkani, A., Astrup, A., Holst, Jens Juul, Madsbad, Sten & Krarup, T., 2019, In: American Journal of Clinical Nutrition. 110, 2, p. 296-304 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Mechanisms of changes in glucose metabolism and bodyweight after bariatric surgery

    Madsbad, Sten, Dirksen, C. & Holst, Jens Juul, Feb 2014, In: The Lancet Diabetes & Endocrinology. 2, 2, p. 152-64 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Mechanisms of gastric emptying disturbances in chronic and acute inflammation of the distal gastrointestinal tract

    Keller, J., Beglinger, C., Holst, Jens Juul, Andresen, V. & Layer, P., Nov 2009, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 297, 5, p. G861-8

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Mechanisms of improved glycaemic control after Roux-en-Y gastric bypass

    Dirksen, C., Jørgensen, N. B., Bojsen-Møller, K. N., Jacobsen, S. H., Hansen, D. L., Worm, Dorte, Holst, Jens Juul & Madsbad, Sten, 2012, In: Diabetologia. 55, 7, p. 1890-901 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Mechanisms of surgical control of type 2 diabetes: GLP-1 is key factor

    Holst, Jens Juul & Madsbad, Sten, Jul 2016, In: Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery. 12, 6, p. 1236-42 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Mechanisms of the incretin effect in subjects with normal glucose tolerance and patients with type 2 diabetes

    Mari, A., Bagger, J. I., Ferrannini, E., Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, T., 2013, In: PLOS ONE. 8, 9, p. e73154

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Mechanisms preserving insulin action during high dietary fat intake

    Lundsgaard, Anne-Marie, Holm, J. B., Sjøberg, K. A., Bojsen-Møller, K. N., Myrmel, L. S., Fjære, E., Jensen, Benjamin Anderschou Holbech, Nicolaisen, T. S., Hingst, J. R., Hansen, S. L., Doll, S., Geyer, P. E., Deshmukh, Atul Shahaji, Holst, Jens Juul, Madsen, L., Kristiansen, Karsten, Wojtaszewski, Jørgen F P, Richter, Erik A. & Kiens, Bente, 2019, In: Cell Metabolism. 29, 1, p. 50-63, e1-e4 19 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Metabolic Dysregulation in Adult Survivors of Pediatric Hematopoietic Stem Cell Transplantation: The Role of Incretins

    Vadmand, A. C., Nissen, A. A., Mathiesen, S., Ebbesen, M. S., Gerbek, T., Fridh, M. K., Sørensen, K., Hartmann, Bolette, Holst, Jens Juul & Muller, Klaus, 2023, In: Journal of Clinical Endocrinology and Metabolism. 108, 2, p. 453–462

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    Metabolic effects of amino acid mixtures and whey protein in healthy subjects: studies using glucose-equivalent drinks

    Nilsson, M., Holst, Jens Juul & Bjorck, I. M. E., 2007, In: American Journal of Clinical Nutrition. 85, 4, p. 996-1004 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    Metabolic effects of beta-lactoglobulin, casein and whey supplementations during controlled catabolic inflammation in humans

    Mose, M., Moller, N., Jessen, N., Mikkelsen, U. R., Christensen, B., Raakvaag, E., Holst, Jens Juul, Jørgensen, J. L. & Rittig, N., 2020, In: Diabetologia. 63, SUPPL 1, p. S240-S240 1 p., 496.

    Research output: Contribution to journal › Conference abstract in journal › Research

  55. Published

    Metabolic effects of one-week binge drinking and fast food intake during Roskilde Festival in young healthy male adults

    Demant, Mia Grønlund, Suppli, M. P., Foghsgaard, S., Gether, L., Grøndahl, M. F. G., Dalsgaard, N. B., Bergmann, S. S., Lanng, A. R., Gasbjerg, Lærke Smidt, Thomasen, M., Bagger, J. I., Strandberg, C., Kønig, M. J., Grønbæk, H., Becker, U., Holst, Jens Juul, Knop, J., Gillum, M. P., Vilsbøll, Tina & Knop, Filip Krag, Apr 2021, In: European Journal of Endocrinology. 185, 1, p. 23-32

    Research output: Contribution to journal › Journal article › Research › peer-review

  56. Published

    Metabolic effects of short-term GLP-1 treatment in insulin resistant heart failure patients

    Nielsen, R., Wiggers, H., Halbirk, M., Bøtker, H., Holst, Jens Juul, Schmitz, O., Frandsen, E. R., Nielsen, S., Møller, N. & Nørrelund, H., 2012, In: Experimental and Clinical Endocrinology and Diabetes. 120, 5, p. 266-72 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  57. Published

    Metabolism of glucagon-like peptide-2 in pigs: role of dipeptidyl peptidase IV.

    Hansen, L., Hare, K. J., Hartmann, B., Deacon, Carolyn F., Ugleholdt, Randi Kjærsgaard, Plamboeck, A. & Holst, Jens Juul, 2006, In: Regulatory Peptides. 138, 2-3, p. 126-32 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  58. Published

    Metabolism of oral glucose in pancreas transplant recipients with normal and impaired glucose tolerance.

    Christiansen, E., Tibell, A., Vølund, A., Holst, Jens Juul, Rasmussen, K., Schäffer, L. & Madsbad, S., 1997, In: J. Clin. Endocrinol. Metab.. 82, p. 2299-2307

    Research output: Contribution to journal › Journal article › Research

  59. Published

    Metformin potentiates bile acid-induced GLP-1 secretion in patients with type 2 diabetes

    Bronden, A., Alber, A., Rohde, U., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2017, In: Diabetologia. 60, p. 113-113 242.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  60. Published

    Metformin protects against lipoapoptosis and enhances GLP-1 secretion from GLP-1-producing cells

    Kappe, C., Patrone, C., Holst, Jens Juul, Zhang, Q. & Sjöholm, A., Mar 2013, In: Journal of Gastroenterology. 48, 3, p. 322-32 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  61. Published

    Metformin stimulates intestinal glycolysis and lactate release: A single-dose study of metformin in patients with intrahepatic portosystemic stent

    Rittig, N., Aagaard, N. K., Sundelin, E., Villadsen, G. E., Sandahl, T. D., Holst, Jens Juul, Hartmann, Bolette, Brøsen, K., Grønbaek, H. & Jessen, N., 2021, In: Clinical Pharmacology and Therapeutics. 110, 5, p. 1329-1336

    Research output: Contribution to journal › Journal article › Research › peer-review

  62. Published

    Metformin-induced glucagon-like peptide-1 secretion contributes to the actions of metformin in type 2 diabetes

    Bahne, E., Sun, E. W. L., Young, R. L., Hansen, M., Sonne, D. P., Hansen, J. S., Rohde, U., Liou, A. P., Jackson, M. L., de Fontgalland, D., Rabbitt, P., Hollington, P., Sposato, L., Due, S., Wattchow, D. A., Rehfeld, Jens Frederik, Holst, Jens Juul, Keating, D. J., Vilsbøll, Tina & Knop, Filip Krag, 2018, In: JCI Insight. 3, 23, p. 1-16 e93936.

    Research output: Contribution to journal › Journal article › Research › peer-review

  63. Published

    Methods and Guidelines for Measurement of Glucagon in Plasma

    Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2019, In: International Journal of Molecular Sciences (Online). 20, 10 p., 5416.

    Research output: Contribution to journal › Review › Research › peer-review

  64. Published

    Milrinone efficiently potentiates insulin secretion induced by orally but not intravenously administered glucose in C57BL6J mice

    Degerman, E., Manganiello, V., Holst, Jens Juul & Ahren, B., 2004, In: Eur. J. Pharmacol.. 498, p. 319-323

    Research output: Contribution to journal › Journal article › Research › peer-review

  65. Published

    Minimal enteral nutrient requirements for intestinal growth in neonatal piglets: how much is enough?

    Burrin, D. G., Stoll, B., Jiang, R., Chang, X., Hartmann, B., Holst, Jens Juul, Greeley, G. H. & Reeds, P. J., 2000, In: Am. J. Clin. Nutr.. 71, p. 1603-1610

    Research output: Contribution to journal › Journal article › Research › peer-review

  66. Published

    Minor Contribution of Endogenous GLP-1 and GLP-2 to Postprandial Lipemia in Obese Men

    Matikainen, N., Björnson, E., Söderlund, S., Borén, C., Eliasson, B., Pietiläinen, K. H., Bogl, L. H., Hakkarainen, A., Lundbom, N., Rivellese, A., Riccardi, G., Després, J., Alméras, N., Holst, Jens Juul, Deacon, Carolyn F., Borén, J. & Taskinen, M., 2016, In: PLOS ONE. 11, 1, p. 1-15 15 p., e0145890.

    Research output: Contribution to journal › Journal article › Research › peer-review

  67. Published

    Molecular Mechanisms of Glucose-Stimulated GLP-1 Secretion From Perfused Rat Small Intestine

    Kuhre, Rune Ehrenreich, Frost, C. R., Svendsen, B. & Holst, Jens Juul, Feb 2015, In: Diabetes. 64, 2, p. 370-382 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  68. Published

    Molecular and in vivo phenotyping of missense variants of the human glucagon receptor

    van der Velden, W. J. C., Lindquist, Peter, Madsen, Jakob Sture, Stassen, R. H. M. J., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Hauser, Alexander Sebastian & Rosenkilde, M. M., 2022, In: Journal of Biological Chemistry. 298, 2, 101413.

    Research output: Contribution to journal › Journal article › Research › peer-review

  69. Published

    Molecular mechanisms of lipoapoptosis and metformin protection in GLP-1 secreting cells

    Kappe, C., Holst, Jens Juul, Zhang, Q. & Sjöholm, A., 12 Oct 2012, In: Biochemical and Biophysical Research Communications. 427, 1, p. 91-5 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  70. Published

    Molecular-scale simulation of electroluminescence in a multilayer white organic light-emitting diode

    Mesta, M., Carvelli, M., de Vries, R. J., van Eersel, H., van der Holst, J. J. M., Schober, M., Furno, M., Lüssem, B., Leo, K., Loebl, P., Coehoorn, R., Bobbert, P. A. & Holst, Jens Juul, Jul 2013, In: Nature Materials. 12, 7, p. 652-8 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  71. Published

    Mono- and co-activation of the GIP and GLP-1 receptors inhibits bone resorption

    Bergmann, N. C., Lund, A., Heimburger, S. M., Gasbjerg, Lærke Smidt, Jørgensen, Niklas Rye, Jessen, L., Hartmann, Bolette, Holst, Jens Juul, Christensen, Mikkel Bring, Vilsbøll, Tina & Knop, Filip Krag, 2018, In: Diabetologia. 61, S.1, p. S348-S348 717.

    Research output: Contribution to journal › Conference abstract in journal › Research

  72. Published

    Morning and afternoon appetite and gut hormone responses to meal and stress challenges in obese individuals with and without binge eating disorder

    Carnell, S., Grillot, C., Ungredda, T., Ellis, S., Mehta, N., Holst, Jens Juul & Geliebter, A., 2018, In: International Journal of Obesity. 42, 4, p. 841-849

    Research output: Contribution to journal › Journal article › Research › peer-review

  73. Published

    N- and C-terminally truncated forms of glucose-dependent insulinotropic polypeptide are high-affinity competitive antagonists of the human GIP receptor

    Hansen, L. S., wbf943, wbf943, Christensen, M., Knop, Filip Krag, Hartmann, Bolette, Holst, Jens Juul & Rosenkilde, Mette, Mar 2016, In: British Journal of Pharmacology. 173, 5, p. 826-838 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  74. Published

    N-terminal alterations turn the gut hormone GLP-2 into an antagonist with gradual loss of GLP-2 receptor selectivity towards more GLP-1 receptor interaction

    Gabe, M. B. N., Gasbjerg, Lærke Smidt, Gadgaard, S., Lindquist, Peter, Holst, Jens Juul & Rosenkilde, Mette, 2022, In: British Journal of Pharmacology. 179, 18, p. 4473-4485

    Research output: Contribution to journal › Journal article › Research › peer-review

  75. Published

    NO has tonic inhibitory, but is not involved in the vagal control or VIP effects on motility of the porcine antrum

    Schmidt, P. T., Ørskov, C., Rasmussen, T. N. & Holst, Jens Juul, 2003, In: Scandinavian Journal of Gastroenterology. 38, p. 955-961

    Research output: Contribution to journal › Journal article › Research › peer-review

  76. Published

    Natural history of insulin sensitivity and insulin secretion in the progression from normal glucose tolerance to impaired fasting glycemia and impaired glucose tolerance: the Inter99 study

    Faerch, K., Vaag, Allan, Holst, Jens Juul, Hansen, Torben, Jørgensen, T. & Borch-Johnsen, K., 2008, In: Diabetes Care. 32, 3, p. 439-44 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  77. Published

    Naturally occurring products of proglucagon 111-160 in the porcine and human small intestine

    Buhl, T., Thim, L., Kofod, H., Ørskov, Cathrine, Harling, H. & Holst, Jens Juul, 25 Jun 1988, In: Journal of Biological Chemistry. 263, 18, p. 8621-4 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  78. Published

    Near normalisation of blood glucose improves the potentiating effect of GLP-1 on glucose-induced insulin secretion in patients with type 2 diabetes

    Højberg, P. V., Zander, M., Vilsbøll, T., Knop, Filip Krag, Krarup, T., Vølund, A., Holst, Jens Juul & Madsbad, Sten, 1 Apr 2008, In: Diabetologia. 51, 4, p. 632-640 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  79. Published

    Near-normalization of glycaemic control with glucagon-like peptide-1 receptor agonist treatment combined with exercise in patients with type 2 diabetes

    Mensberg, P., Nyby, S., Jørgensen, P. G., Storgaard, H., Jensen, M. T., Sivertsen, J., Holst, Jens Juul, Kiens, Bente, Richter, Erik A., Knop, Filip Krag & Vilsbøll, Tina, 2017, In: Diabetes, Obesity and Metabolism. 19, 2, p. 172-180 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  80. Published

    Neprilysin Inhibition Increases Glucagon Levels in Humans and Mice With Potential Effects on Amino Acid Metabolism

    Kjeldsen, Sasha Alexandra Sampson, Hansen, L. H., Esser, N., Mongovin, S., Winther-Sørensen, Marie, Galsgaard, Katrine Douglas, Dal, Jenna Elizabeth Hunt, Kissow, Hannelouise, Ceutz, F. R., Terzic, D., Mark, P. D., Plomgaard, Peter Stendahl, Goetze, Jens P. , Goossens, G. H., Blaak, E. E., Deacon, Carolyn F., Rosenkilde, Mette, Zraika, S., Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2021, In: Endocrine Research. 5, 9, 15 p., bvab084.

    Research output: Contribution to journal › Journal article › Research › peer-review

  81. Published

    Neprilysin activity is increased in metabolic dysfunction-associated steatotic liver disease and normalizes after bariatric surgery or GLP-1 therapy

    Kjeldsen, S. A. S., Gluud, L. L., Werge, M. P., Pedersen, J. S., Bendtsen, F., Alexiadou, K., Tan, T., Torekov, S. S., Iepsen, E. W., Jensen, N. J., Richter, M. M., Goetze, J. P., Rungby, J., Hartmann, B., Holst, J. J., Holst, B., Holt, J., Gustafsson, F., Madsbad, S., Svane, M. S. & 2 others, Bojsen-Møller, K. N. & Albrechtsen, Nicolai Jacob Wewer, 2023, In: iScience. 26, 11, 13 p., 108190.

    Research output: Contribution to journal › Journal article › Research › peer-review

  82. Published

    Neprilysin inhibition increases plasma glucagon concentrations in humans with possible implications for hepatic amino acid metabolism

    Liver-Alpha-Cell Axis Grp, L. A. G., 2020, In: Diabetologia. 63, SUPPL 1, p. S72-S72 1 p., 144.

    Research output: Contribution to journal › Conference abstract in journal › Research

  83. Published

    Nerve fibers in the rat posterior pituitary lobe contain Prosomatostatin (1-64)

    Mikkelsen, J. D., Bersani, M., Holst, Jens Juul & Larsen, P. J., 1991, In: Neuroendocrinology. 54, p. 469-476

    Research output: Contribution to journal › Journal article › Research › peer-review

  84. Published

    Nervous control of the release of substance P and neurokinin A from the isolated perfused porcine ileum

    Schmidt, P., Rasmussen, T. N. & Holst, Jens Juul, 1992, In: J. of the Autonomic Nerv. System. 38, p. 85-96

    Research output: Contribution to journal › Journal article › Research › peer-review

  85. Published

    Neural regulation of glucagon-like peptide- 1 secretion in pigs

    Hansen, L., Lampert, S., Mineo, H. & Holst, Jens Juul, 2004, In: Am. J. Physiol.. 287, p. E939-E947

    Research output: Contribution to journal › Journal article › Research › peer-review

  86. Published

    Neural regulation of glucagon-like peptide-1 secretion in pigs

    Hansen, L., Lampert, S., Mineo, H. & Holst, Jens Juul, Nov 2004, In: American Journal of Physiology: Endocrinology and Metabolism. 287, 5, p. E939-47

    Research output: Contribution to journal › Journal article › Research › peer-review

  87. Published

    Neural regulation of pancreatic exocrine funktion

    Holst, Jens Juul, 1993, In: The Pancreas: Biology, Pathobiology an Disease. p. 381-402

    Research output: Contribution to journal › Journal article › Research › peer-review

  88. Published

    Neurogenic nitric oxide and exocrine secretion in the gastrointestinal tract

    Ørskov, Cathrine & Holst, Jens Juul, 2000, Nitric Oxide and the Peripheral Nervous System. London, UK: Portland Press Ltd., p. 131

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  89. Published

    Neuromediators in the control of pancreatic secretion

    Holst, Jens Juul, 1993, Neuromediators in the control of pancreatic secretion. Torun: Polish Physiological Society, p. 72-78

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  90. Published

    Neuromedin U Does Not Act as a Decretin in Rats

    Kuhre, Rune Ehrenreich, Christiansen, Charlotte Bayer, Ghiasi, S. M., Gabe, M. B. N., Skat-Rørdam, P. A., Modvig, Ida Marie, Mandrup-Poulsen, Thomas, Albrechtsen, Reidar, Rosenkilde, Mette, Hartmann, Bolette, Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 2019, In: Cell Metabolism. 29, 3, p. 719-726.e1-e5 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  91. Published

    Neuropeptide Y (NPY) and vasoactive intestinal polypeptide (VIP), but not galanin, are autonomic cotransmitters in the porcine pancreas

    Messell, T., Dunning, B. E., Sheikh, S. & Holst, Jens Juul, 1991, In: International Journal of Gastrointestinal Cancer. 10, p. 133-141

    Research output: Contribution to journal › Journal article › Research › peer-review

  92. Published

    Neuroprotective properties of GLP-1: theoretical and practical applications

    Holst, Jens Juul, Burcelin, R. & Nathanson, E., 2011, In: Current Medical Research and Opinion. 27, 3, p. 547-58 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  93. Published

    Neurotensin Is Co-Expressed, Co-Released And Acts Together With Glp-1 And Pyy In Enteroendocrine Control Of Metabolism

    Grunddal, Kaare Villum, Ratner, C. F., Svendsen, B., Sommer, F., Engelstoft, M. S., Madsen, A. N., Pedersen, Jens, Nøhr, M. K., Egerod, Kristoffer Lihme, Nawrocki, A. R., Kowalski, T., Howard, A. D., Poulsen, Steen Seier, Offermanns, S., Bäckhed, G. F., Holst, Jens Juul, Holst, Birgitte & Schwartz, Thue W., Jan 2016, In: Endocrinology. 157, 1, p. 176-94 19 p., en20151600.

    Research output: Contribution to journal › Journal article › Research › peer-review

  94. Published

    Neurotensin secretion after Roux-en-Y gastric bypass, sleeve gastrectomy, and truncal vagotomy with pyloroplasty

    Svane, M. S., Øhrstrøm, C. C., Plamboeck, A., Jørgensen, Nils Bruun, Bojsen-Møller, K. N., Dirksen, C., Martinussen, C., Vilsbøll, Tina, Hartmann, Bolette, Deacon, Carolyn F., Kristiansen, V. B., Knop, Filip Krag, Svendsen, Lars Bo, Madsbad, Sten, Holst, Jens Juul & Veedfald, Simon, 2022, In: Neurogastroenterology and Motility. 34, 1, e14210.

    Research output: Contribution to journal › Journal article › Research › peer-review

  95. Published

    Neutral Endopeptidase 24.11 and dipeptidyl peptidase IV are both physiological mediators of the degradation of glucagon-like peptide-1 in the anaesthetized pig

    Plamboeck, A., Holst, Jens Juul, Carr, R. D. & Deacon, Carolyn F., 2005, In: Diabetologia. 48, p. 1882-1890

    Research output: Contribution to journal › Journal article › Research › peer-review

  96. Published

    Neutral endopeptidase 24.11 and dipeptidyl peptidase IV are both involved in regulating the metabolic stability of glucagon-like peptide-1 in vivo.

    Plamboeck, A., Holst, Jens Juul, Carr, R. D. & Deacon, Carolyn F., 2003, In: Advances in Experimental Medicine and Biology. 524, p. 303-12 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  97. Published

    Neutral endopeptidase 24.11 and dipeptidyl peptidase IV are both mediators of the degradation of glucagon-like peptide 1 in the anaesthetised pig

    Plamboeck, A., Holst, Jens Juul, Carr, R. D. & Deacon, Carolyn F., Sep 2005, In: Diabetologia. 48, 9, p. 1882-90 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  98. Published

    Neutral endopeptidase 24.11 is important for the degradation of both endogenous and exogenous glucagon in anesthetized pigs.

    Trebbien, R., Klarskov, L., Olesen, M., Holst, Jens Juul, Carr, R. D. & Deacon, Carolyn F., 2004, In: American Journal of Physiology: Endocrinology and Metabolism. 287, 3, p. E431-8

    Research output: Contribution to journal › Journal article › Research › peer-review

  99. Published

    New Lessons from the gut: Studies of the role of gut peptides in weight loss and diabetes resolution after gastric bypass and sleeve gastrectomy

    Holst, Jens Juul, Madsbad, Sten, Bojsen-Møller, Kirstine Nyvold, Dirksen, C. & Svane, M., 2024, In: Peptides. 176, 9 p., 171199.

    Research output: Contribution to journal › Review › Research › peer-review

  100. Published

    New horizons in diabetes therapy

    Holst, Jens Juul & Deacon, Carolyn F., 2007, In: Immunology, Endocrine and Metabolic Agents in Medicinal Chemistry. 7, 1, p. 49-55 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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