Jens Juul Holst
Professor
Endocrinology and Metabolism
Blegdamsvej 3
2200 København N.
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Do sodium-glucose transporter-2 inhibitors increase plasma glucagon by direct actions on the alpha-cell? - and does the increase matter for the associated increase in endogenous glucose production?
Kuhre, Rune Ehrenreich, Deacon, Carolyn F., Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 2021, In: Diabetes, Obesity and Metabolism. 23, 9, p. 2009-2019Research output: Contribution to journal › Review › Research › peer-review
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Do the actions of glucagon-like peptide-1 on gastric emptying, appetite, and food intake involve release of amylin in humans?
Asmar, M., Bache, M., Knop, Filip Krag, Madsbad, Sten & Holst, Jens Juul, 1 May 2010, In: The Journal of clinical endocrinology and metabolism. 95, 5, p. 2367-75 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Do we know the true mechanism of action of the DPP-4 inhibitors?
Andersen, E. S., Deacon, Carolyn F. & Holst, Jens Juul, 2018, In: Diabetes, Obesity and Metabolism. 20, 1, p. 34-41 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Does a GLP-1 receptor agonist change glucose tolerance in patients treated with antipsychotic medications? Design of a randomised, double-blinded, placebo-controlled clinical trial
Larsen, J. R., Vedtofte, L., Holst, Jens Juul, Oturai, P., Kjær, Andreas, Corell, C. U., Vilsbøll, T. & Fink-Jensen, Anders, 2014, In: B M J Open. 4, 3, p. 1-9 9 p., e004227.Research output: Contribution to journal › Journal article › Research › peer-review
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Does glucose lowering restore GIP's effect on insulin secretion?
Madsbad, Sten, Knop, Filip Krag & Holst, Jens Juul, 2023, In: Nutrition, Metabolism & Cardiovascular Diseases. 33, 9, p. 1817-1818Research output: Contribution to journal › Comment/debate › Research
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Does overnight normalization of plasma glucose by insulin infusion affect assessment of glucose metabolism in type 2 diabetes
Staehr, P., Højlund, K., Hother-Nielsen, O., Holst, Jens Juul & Beck-Nielsen, H., 2003, In: Diabetic Medicine. 20, p. 816-822Research output: Contribution to journal › Journal article › Research › peer-review
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Dose response of continuous subcutaneous infusion of recombinant glucagon-like peptide-1 in combination with metformin and sulphonylurea over 12 weeks in patients with type 2 diabetes mellitus
Torekov, Signe Sørensen, Holst, Jens Juul & Ehlers, M. R., May 2014, In: Diabetes, Obesity and Metabolism. 16, 5, p. 451-6 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Dose response of subcutaneous GLP-1 infusion in patients with type 2 diabetes
Torekov, Signe Sørensen, Kipnes, M. S., Harley, R. E., Holst, Jens Juul & Ehlers, M. R., 2011, In: Diabetes, Obesity and Metabolism. 13, 7, p. 639-43 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Dose-dependent efficacy of the glucose-dependent insulinotropic polypeptide (GIP)receptor antagonistGIP(3-30)NH2 on GIP actions in humans
Gasbjerg, Lærke Smidt, Bari, E. J., Stensen, S., Hoe, B., Lanng, A. R., Mathiesen, D. S., Christensen, Mikkel Bring, Hartmann, Bolette, Holst, Jens Juul, Rosenkilde, Mette & Knop, Filip Krag, 2021, In: Diabetes, Obesity and Metabolism. 23, 1, p. 68-74Research output: Contribution to journal › Journal article › Research › peer-review
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Double incretin receptor knockout (DIRKO) mice reveal an essential role for the enteroinsular axis in transducing the glucoregulatory actions of DPP-IV inhibitors
Hansotia, T., Baggio, L. L., Delmeire, D., Hinke, S. A., Yamada, Y., Tsukiyama, K., Seino, Y., Holst, Jens Juul, Schuit, F. & Drucker, D. J., 2004, In: Diabetes. 53, p. 1326-1335Research output: Contribution to journal › Journal article › Research › peer-review
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Double incretin receptor knockout (DIRKO) mice reveal an essential role for the enteroinsular axis in transducing the glucoregulatory actions of DPP-IV inhibitors
Hansotia, T., Baggio, L. L., Delmeire, D., Hinke, S. A., Yamada, Y., Tsukiyama, K., Seino, Y., Holst, Jens Juul, Schuit, F. & Drucker, D. J., May 2004, In: Diabetes. 53, 5, p. 1326-35 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Drug-induced blockade of the voltage-gated potassium channel Kv11.1 (hERG-channel) decreases glucose-stimulated insulin secretion and increases insulin sensitivity
Juhl, C., Burgdorf, J., Knudsen, C., Veedfald, Simon, Holst, Jens Juul, Kanters, Jørgen K. & Torekov, Signe Sørensen, 2020, In: Diabetologia. 63, SUPPL 1, p. S232-S233 2 p., 479.Research output: Contribution to journal › Conference abstract in journal › Research
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Dual-hormone treatment with insulin and glucagon in patients with type 1 diabetes
Reiband, H. K., Schmidt, S., Ranjan, A., Holst, Jens Juul, Madsbad, Sten & Nørgaard, Kirsten, 2015, In: Diabetes - Metabolism: Research and Reviews (Print Edition). 31, 7, p. 672-9 8 p.Research output: Contribution to journal › Review › Research › peer-review
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Duodenal Anaerobutyricum soehngenii infusion stimulates GLP-1 production, ameliorates glycaemic control and beneficially shapes the duodenal transcriptome in metabolic syndrome subjects: a randomised double-blind placebo-controlled cross-over study
Koopen, A., Witjes, J., Wortelboer, K., Majait, S., Prodan, A., Levin, E., Herrema, H., Winkelmeijer, M., Aalvink, S., Bergman, J. J. G. H. M., Havik, S., Hartmann, B., Levels, H., Bergh, P-O., van Son, J., Balvers, M., Bastos, D. M., Stroes, E., Groen, A. K., Henricsson, M. & 8 others, , 2022, In: Gut. 71, p. 1577-1587 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Dynamics of glucagon secretion in mice and rats revealed using a validated sandwich ELISA for small sample volumes.
Albrechtsen, Nicolai Jacob Wewer, Kuhre, Rune Ehrenreich, Windeløv, Johanne Agerlin, Ørgaard, A., Deacon, Carolyn F., Kissow, Hannelouise, Hartmann, Bolette & Holst, Jens Juul, 2016, In: American Journal of Physiology: Endocrinology and Metabolism. 311, 2, p. E302-E309 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Early differential defects of insulin secretion and action in 19-year-old caucasian men who had low birth weight.
Jensen, C. B., Storgaard, H., Dela, Flemming, Holst, Jens Juul, Madsbad, Sten & Vaag, Allan, 2002, In: Diabetes. 51, 4, p. 1271-80 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Early effects of Roux-en-Y gastric bypass on dietary fatty acid absorption and metabolism in people with obesity and normal glucose tolerance
Hindsø, M., Bojsen-Møller, K. N., Kristiansen, V. B., Holst, Jens Juul, van Hall, Gerrit & Madsbad, Sten, 2022, In: International Journal of Obesity. 46, 7, p. 1359-1365Research output: Contribution to journal › Journal article › Research › peer-review
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Early enhancements of hepatic and later of peripheral insulin sensitivity combined with increased postprandial insulin secretion contribute to improved glycemic control after Roux-en-Y gastric bypass
Bojsen-Møller, K. N., Dirksen, C., Jørgensen, N. B., Jacobsen, S. H., Serup, A. K. L., Albers, P. H., Hansen, D. L., Worm, D., Naver, L., Kristiansen, V. B., Wojtaszewski, Jørgen F P, Kiens, Bente, Holst, Jens Juul, Richter, Erik A. & Madsbad, Sten, 2014, In: Diabetes. 63, 5, p. 1725-1737 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Early gradual feeding with bovine colostrum improves gut function and NEC resistance relative to infant formula in preterm pigs
Shen, René Liang, Thymann, Thomas, Østergaard, M. V., Støy, A. C. F., Krych, Lukasz, Nielsen, Dennis Sandris, Lauridsen, C., Hartmann, Bolette, Holst, Jens Juul, Burrin, D. G. & Sangild, Per Torp, 2015, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 309, 5, p. G310-G323 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Early growth and postprandial appetite regulatory hormone responses
Perälä, M., Kajantie, E., Valsta, L. M., Holst, Jens Juul, Leiviskä, J. & Eriksson, J. G., 19 Apr 2013, In: British Journal of Nutrition. 110, 09, p. 1-10 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Early phase glucagon and insulin secretory abnormalities, but not incretin secretion, are similarly responsible for hyperglycemia after ingestion of nutrients
Yabe, D., Kuroe, A., Watanabe, K., Iwasaki, M., Hamasaki, A., Hamamoto, Y., Harada, N., Yamane, S., Lee, S., Murotani, K., Deacon, Carolyn F., Holst, Jens Juul, Hirano, T., Inagaki, N., Kurose, T. & Seino, Y., 2015, In: Journal of Diabetes and its Complications. 29, p. 413-421 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of 17-norleucine-VIP on gastroduodenal motility relative to serum VIP concentration and blockade of NOS.
Holle, G. E., Steinbach, E., Wünsch, E. & Holst, Jens Juul, 1995, In: Am. J. Physiol.. 269, p. G584-G590Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of 6 weeks of very low-volume high-intensity interval training on oral glucose-stimulated incretin hormone response
Hindsø, M., Kuhlman, A. B., Dohlmann, T. L., Lund, M. T., Hartmann, Bolette, Holst, Jens Juul, Larsen, Steen & Helge, Jørn Wulff, 2022, In: European Journal of Sport Science. 22, 3, p. 381-389Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of 6-week course of glucagon-like peptide 1 on glycaemic control, insulin sensitivity, and beta-cell function in type 2 diabetes: a parallel-group study.
Olsen, Ane Mette Zander, Madsbad, Sten, Madsen, J. L. & Holst, Jens Juul, 2002, In: Lancet. 359, 9309, p. 824-30 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Effect of Antibiotics on Gut Microbiota, Gut Hormones and Glucose Metabolism
Mikkelsen, K. H., Frost, M., Bahl, M. I., Licht, T. R., Jensen, U. S., Rosenberg, Jacob, Pedersen, Oluf Borbye, Hansen, Torben, Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, T. & Knop, Filip Krag, 12 Nov 2015, In: PLOS ONE. 10, 11, p. 1-14 e0142352.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 4207
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Meal induced gut hormone secretion is altered in aerobically trained compared to sedentary young healthy males
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Copenhagen study of overweight patients with coronary artery disease undergoing low energy diet or interval training: the randomized CUT-IT trial protocol
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Whole grain-rich diet reduces body weight and systemic low-grade inflammation without inducing major changes of the gut microbiome: a randomised cross-over trial
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