Jens Juul Holst

Jens Juul Holst

Professor

ORCID: 0000-0001-6853-3805

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  1. Published

    Incretins, insulin secretion and Type 2 diabetes mellitus

    Vilsbøll, T. & Holst, Jens Juul, Mar 2004, In: Diabetologia. 47, 3, p. 357-66 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Incretins, insulin secretion and type 2 diabetes mellitus

    Vilsboll, T. & Holst, Jens Juul, 2004, In: Diabetologia. 47, p. 654-662

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Individual and combined glucose-lowering effects of glucagon receptor antagonism and dipeptidyl peptidase-4 inhibition

    Maagensen, H., Haedersdal, S., Lund, A., Nielsen-Hannerup, E., Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2018, In: Diabetologia. 61, p. S246-S247

    Research output: Contribution to journal › Conference abstract in journal › Research

  4. Published

    Individual and combined glucose-lowering effects of glucagon receptor antagonism and sodium-glucose cotransporter 2 inhibition

    Haedersdal, S., Lund, A., Maagensen, H., Nielsen-Hannerup, E., Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2018, p. S312-S312.

    Research output: Contribution to conference › Poster › Research

  5. Published

    Individuals with type 2 diabetes have higher density of small intestinal neurotensin-expressing cells

    Ferreira, F. P., Pereira, S. S., Costa, M. M., Guimarães, M., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Nora, M. & Monteiro, M. P., 2023, In: Molecular and Cellular Biochemistry. 478, 12, p. 2779-2787

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Indole-3-carboxyaldehyde does not reverse the intestinal effects of fiber-free diet in mice

    Smits, Mark, Dreyer, S. I. L., Dal, Jenna Elizabeth Hunt, Drzazga, Anna Katarzyna, Modvig, Ida Marie, Holst, Jens Juul & Kissow, Hannelouise, 2024, In: Frontiers in Endocrinology. 15, 10 p., 1362711.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Induction of insulin and islet amyloid polypeptide production in pancreatic islet glucagonoma cells by insulin promoter factor 1

    Serup, P., Jensen, J., Andersen, F. G., Jørgensen, Mette Christine, Blume, N., Holst, Jens Juul & Madsen, O. D., 20 Aug 1996, In: Proceedings of the National Academy of Sciences of the United States of America. 93, 17, p. 9015-20 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Influence of GLP-1 on myocardial glucose metabolism in healthy men during normo- or hypoglycemia

    Gejl, M., Lerche, S., Mengel, A., Møller, N., Bibby, B. M., Smidt, K., Brock, Birgitte, Søndergaard, H., Bøtker, H. E., Gjedde, Albert, Holst, Jens Juul, Hansen, S. B. & Rungby, J., 2014, In: PLOS ONE. 9, 1, p. 1-10 10 p., e83758.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Influence of acarbose on postprandial insulin requirements in patients with type 1 diabetes

    Juntti-Berggren, L., Pigon, J., Hellström, P. M., Holst, Jens Juul & Efendic, S., 2000, In: Diab Nutr Metab. 13, p. 7-12

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Influence of erythropoietin on cognitive performance during experimental hypoglycemia in patients with type 1 diabetes mellitus: A Randomized Cross-Over Trial

    Kristensen, Peter Lommer, Pedersen-Bjergaard, Ulrik, Kjær, T. W., Olsen, N. V., Dela, Flemming, Holst, Jens Juul, Faber, Jens, Tarnow, L. & Thorsteinsson, B., 5 Apr 2013, In: P L o S One. 8, 4, p. 1-8 8 p., e59672.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Influence of gastric inhibitory polypeptide on pentagastrin-stimulated gastric acid secretion in patients with type 2 diabetes and healthy controls.

    Meier, J. J., Nauck, M. A., Kask, B., Holst, Jens Juul, Deacon, Carolyn F., Schmidt, W. E. & Gallwitz, B., 2006, In: World Journal of Gastroenterology. 12, 12, p. 1874-80 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Influence of gastrointestinal factors on glucose metabolism in patients with cirrhosis

    Junker, A. E., Gluud, Lise Lotte, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, Oct 2015, In: Journal of Gastroenterology and Hepatology. 30, 10, p. 1522-8 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Influence of glucagon-like peptide 1 on fasting glycemia in type 2 diabetic patients treated with insulin after sulfonylurea secondary failure

    Nauck, M. A., Sauerwald, A., Ritzel, R., Holst, Jens Juul & Schmiegel, W., 1998, In: Diabetes Care. 21, p. 1925-1931

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Influence of peptides on anorectal function

    Christiansen, J., Lorentzen, M. & Holst, Jens Juul, 1991, In: Annals of Medicine. 22, p. 413-418

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Influence of short term verapamil treatment on glucose metabolism in patients with non-insulin dependent diabetes mellitus

    Busch Sørensen, M., Sjøstrand, H., Holst, Jens Juul, Sengeløv, H., Tiefenthal Thrane, M. & Lyngsøe, J., 1991, In: EUR. J. Clin. Pharmacol.. 41, p. 401-404

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Infrared thermographic assessment of changes in skin temperature during hypoglycaemia in patients with type 1 diabetes

    Sejling, A., Lange, Kai, Frandsen, C. S., Diemar, S. S., Tarnow, L., Faber, Jens, Holst, Jens Juul, Hartmann, Bolette, Hilsted, Linda, Kjaer, T. W., Juhl, C. B., Thorsteinsson, B. & Pedersen-Bjergaard, Ulrik, 2015, In: Diabetologia. 58, p. 1898–1906 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Inhibiting RHOA Signaling in Mice Increases Glucose Tolerance and Numbers of Enteroendocrine and Other Secretory Cells in the Intestine

    Petersen, N., Frimurer, Thomas Michael, Pedersen, M. T., Egerod, Kristoffer Lihme, Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Grapin-Botton, A., Jensen, Kim Bak & Schwartz, Thue W., 2018, In: Gastroenterology. 155, 4, p. 1164-1176 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Inhibition de la sécrétion du glucagon par les antagonistes du GLP-1 et les inhibiteurs de la DPP-4

    Hansen, M., Knop, Filip Krag & Holst, Jens Juul, Apr 2011, In: Medecine des Maladies Metaboliques. 5, 2

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Inhibition of DPP-4 with vildagliptin improved insulin secretion in response to oral as well as "isoglycemic" intravenous glucose without numerically changing the incretin effect in patients with type 2 diabetes

    Vardarli, I., Nauck, M. A., Köthe, L. D., Deacon, Carolyn F., Holst, Jens Juul, Schweizer, A. & Foley, J. E., 2011, In: Journal of Clinical Endocrinology and Metabolism. 96, 4, p. 945-954 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Inhibition of dipeptidyl peptidase IV with NVP DPP728 increases plasma GLP-1 (7-36amide) concentrations and improves oral glucose tolerance in obese Zucker rats

    Balkan, B., Kwasnik, L., Miserendino, R., Holst, Jens Juul & Lie, X., 1999, In: Diabetologia. 42, p. 1324-1331

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Inhibition of gastric emptying by acarbose is correlated with GLP-1 response and accompanied by CCK release

    Enc, F. Y., Imeryuz, N., Akin, L. & Holst, Jens Juul, 2001, In: Am J Physiol-Gastr L. 281, p. G752-G763

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Inhibition of gastric inhibitory polypeptide signaling prevents obesity.

    Miyawaki, K., Yamada, Y., Ban, N., Ihara, Y., Tsukiyama, K., Zhou, H., Fujimoto, S., Oku, A., Tsuda, K., Toyokuni, S., Hiai, H., Mizunoya, W., Fushiki, T., Holst, J. J., Makino, M., Tashita, A., Kobara, Y., Tsubamoto, Y., Jinnouchi, T., Jomori, T. & 1 others, Seino, Y., 2002, In: Nature Medicine. 8, 7, p. 738-42 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Inhibition of glucagon secretion by GLP-1 agonists and DPP4 inhibitors

    Hansen, M., Juul Hare, K., Holst, Jens Juul & Knop, Filip Krag, Jun 2011, In: Journal of Clinical Metabolism & Diabetes. 2, 2, p. 7-13 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Inhibition of human gastric lipase secretion by glucagon-like peptide-1

    Wojdemann, M., Wettergren, A., Sternby, B., Holst, Jens Juul, Larsen, S., Rehfeld, J. F. & Olsen, O., 1998, In: Dig. Dis. Sci.. 43, p. 799-805

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Inhibition of human pancreatic and biliary output but not intestinal motility by physiological intraileal lipid loads.

    Keller, J., Holst, Jens Juul & Layer, P., 2005, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 290, 4, p. G704-9

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Inhibition of neutral endopeptidase 24.11 does not potentiate the improvement in glycemic control obtained with dipeptidyl peptidase-4 inhibition in diabetic Goto-Kakizaki rats

    Simonsen, L., Pilgaard, S., Carr, R. D., Kanstrup, A. B., Holst, Jens Juul & Deacon, Carolyn F., 2009, In: Hormone and Metabolic Research. 41, 11, p. 851-3 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Inhibition of shamfeeding stimulated human gastric acid secretion by glucagon-like peptide-2

    Wøjdemann, M., Wettergren, A., Hartmann, B., Hilsted, L. M. & Holst, Jens Juul, 1999, In: J. Clin. Endocrinol. Metab.. 84, p. 2513-2517

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Inhibition of the activity of dipeptidyl-peptidase IV as a treatment for type 2 diabetes

    Holst, Jens Juul & Deacon, Carolyn F., 1998, In: Diabetes. 47, p. 1663-1670

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Inhibitors of dipeptidyl peptidase IV: a novel approach for the prevention and treatment of Type 2 diabetes?

    Deacon, Carolyn F., Ahrén, B. & Holst, Jens Juul, 2004, In: Expert Opinion on Investigational Drugs. 13, 9, p. 1091-102 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Inhibitory effect of GLP-1 on gastric motility persists after vagal deafferentation in pigs.

    Nagell, C. F., Wettergren, A., Ørskov, Cathrine & Holst, Jens Juul, 2006, In: Scandinavian Journal of Gastroenterology. 41, 6, p. 667-72 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Inhibitory effect of glucagon-like peptide-1 on small bowel motility. Fasting but not fed motility inhibited via nitric oxide independently of insulin and somatostatin

    Tolessa, T., Gutniak, M. K., Holst, Jens Juul, Efendic, S. & Hellstrom, P. M., 1998, In: J. Clin. Invest.. 102, p. 764-774

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Inkretiner

    Vilsbøll, Tina & Holst, Jens Juul, 2011, Diabetes - sygdom, behandling og organisation. Hilsted, J., Borch-Johnsen, K. & Christiansen, J. S. (eds.). 2 ed. København: Munksgaard , p. 67-74 8 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication

  33. Published

    Instrumentalization of eating improves weight loss maintenance in obesity

    Christensen, Bodil Just, Iepsen, E. P. W., Lundgren, J. R., Holm, Lotte, Madsbad, Sten, Holst, Jens Juul & Torekov, Signe Sørensen, 2017, In: Obesity Facts. 10, 6, p. 633-647 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Insufficient sleep predicts poor weight loss maintenance after one year

    Bogh, A. F., Jensen, Simon Birk Kjær, Juhl, C. R., Janus, C., Sandsdal, Rasmus Michael, Lundgren, J. R., Noer, M. H., Vu, N. Q., Fiorenza, Matteo, Stallknecht, Bente Merete, Holst, Jens Juul, Madsbad, Sten & Torekov, Signe Sørensen, 2023, In: Sleep. 46, 5, 12 p., zsac295.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Insulin Plays a Permissive Role for the Vasoactive Effect of GIP Regulating Adipose Tissue Metabolism in Humans

    Asmar, M., Simonsen, L., Asmar, Ali, Holst, Jens Juul, Dela, Flemming & Bülow, J., Aug 2016, In: Journal of Clinical Endocrinology and Metabolism. 101, 8, p. 3155-62 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Insulin Resistance is Accompanied by Increased Fasting Glucagon and Delayed Glucagon Suppression in Individuals With Normal and Impaired Glucose Regulation

    Faerch, K., Vistisen, D., Pacini, G., Torekov, Signe Sørensen, Johansen, N. B., Witte, D. R., Jonsson, Anna Elisabet, Pedersen, Oluf Borbye, Hansen, Torben, Lauritzen, T., Jørgensen, M. E., Ahrén, B. & Holst, Jens Juul, 8 Aug 2016, In: Diabetes. 65, 11, p. 3473-3481 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Insulin Secretion Depends on Intra-islet Glucagon Signaling

    Svendsen, B., Larsen, Olav, Gabe, M. B. N., Christiansen, Charlotte Bayer, Rosenkilde, M. M., Drucker, D. J. & Holst, Jens Juul, 2018, In: Cell Reports. 25, 5, p. 1127-1134.E2

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Insulin and Glucagon: Partners for Life

    Holst, Jens Juul, Holland, W., Gromada, J., Lee, Y., Unger, R. H., Yan, H., Sloop, K. W., Kieffer, T. J., Damond, N. & Herrera, P. L., 1 Apr 2017, In: Endocrinology. 158, 4, p. 696-701 6 p.

    Research output: Contribution to journal › Review › Research › peer-review

  39. Published

    Insulin resistance alters islet morphology in nondiabetic humans

    Mezza, T., Muscogiuri, G., Sorice, G. P., Clemente, G., Hu, J., Pontecorvi, A., Holst, Jens Juul, Giaccari, A. & Kulkarni, R. N., Mar 2014, In: Diabetes. 63, 3, p. 994-1007 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Insulin secretion and cellular glucose metabolism after prolonged low-grade intralipid infusion in young men

    Jensen, C. B., Storgaard, H., Holst, Jens Juul, Dela, F., Madsbad, Sten & Vaag, A. A., 2003, In: Journal of Clinical Endocrinology and Metabolism. 88, 6, p. 2775-2783 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Insulin secretion and cellular glucose metabolism after prolonged low-grade intralipid infusion in young men

    Jensen, C. B., Storgaard, H., Holst, Jens Juul, Dela, Flemming, Madsbad, Sten & Vaag, Allan, Jun 2003, In: The Journal of clinical endocrinology and metabolism. 88, 6, p. 2775-83 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Insulin secretion and incretin hormones after oral glucose in impaired glucose tolerance

    Rask, E., Olsson, T., Söderberg, S., Holst, Jens Juul, Tura, A., Pacini, G. & Ahren, B., 2004, In: Metabolism. 53, p. 624-631

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Insulin secretion and incretin hormones after oral glucose in non-obese subjects with impaired glucose tolerance

    Rask, E., Olsson, T., Söderberg, S., Holst Jj, J. J., Tura, A., Pacini, G., Ahrén, B. & Holst, Jens Juul, May 2004, In: Metabolism. 53, 5, p. 624-31 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Insulin secretion in lipodystrophic HIV-infected patients is associated with high levels of nonglucose secretagogues and insulin resistance of beta-cells.

    Haugaard, S. B., Andersen, Ove, Storgaard, H., Dela, Flemming, Holst, Jens Juul, Iversen, J., Nielsen, J. O. & Madsbad, Sten, 2004, In: American Journal of Physiology: Endocrinology and Metabolism. 287, 4, p. E677-85 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Insulin sensitivity, insulin release and glucagon-like peptide-1 levels in persons with impaired fasting glucose and/or impaired glucose tolerance in the EUGENE2 study

    Laakso, M., Zilinskaite, J., Hansen, Torben, Boesgaard, T. W., Vänttinen, M., Stancáková, A., Jansson, P., Pellmé, F., Kuulasmaa, T., Hribal, M. L., Sesti, G., Stefan, N., Fritsche, A., Häring, H., Pedersen, Oluf Borbye, Smith, U., EUGENE2 Consortium, E. C. & Holst, Jens Juul, 2008, In: Diabetologia. 51, 3, p. 502-11 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Insulin-like growth factor I and glucagon-like peptide-2 responses to fasting followed by controlled or ad libitum refeeding in rats

    Nelson, D. W., Murali, S. G., Liu, X., Koopmann, M. C., Holst, Jens Juul & Ney, D. M., Apr 2008, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 294, 4, p. R1175-84

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Insulin-like growth factor I and glucagon-like peptide-2 responses to fasting followed by controlled or ad libitum refeeding in rats

    Nelson, D. W., Murali, S. G., Liu, X. W., Koopmann, M. C., Holst, Jens Juul & Ney, D. M., 2008, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 294, 4, p. R1175-R1184

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Insulinets vej ind i det danske samfund

    Larsen, Erik Hviid & Holst, Jens Juul, 2010, Det fremmede som historisk drivkraft. Danmark efter 1742: Et festskrift til Hendes Majestæt Dronning Margrethe II ved 70-års-fødselsdagen den 16. april 2010. Nielsen, M. A. (ed.). København: Det Kongelige Danske Videnskabernes Selskab, p. 85-94

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication

  49. Published

    Insulinotropic effect of endogenously secreted incretins after gastric bypass and sleeve gastrectomy

    Madsbad, Sten & Holst, Jens Juul, 2023, In: Obesity. 31, 11, p. 2723-2724 2 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  50. Published

    Insulinotropic effect of gastric inhibitory polypeptide (GIP) in women with a history of gestational diabetes

    Meier, J. J., Gallwitz, B., Askenas, M., Vollmer, K., Deacon, Carolyn F., Holst, Jens Juul, Schmidt, W. E. & Nauck, M. A., 2005, In: Diabetologia. 48, p. 1872-1881

    Research output: Contribution to journal › Journal article › Research

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