Jens Juul Holst

Jens Juul Holst

Professor


  1. Published

    Insulintropic actions of intravenous glucagon-like peptide-1 (GLP-1) (7-36 amide) in the fasting state in healthy subjects

    Qualmann, C., Nauck, M. A., Holst, Jens Juul, Ørskov, Cathrine & Creutzfeldt, W., 1995, In: Acta Diabetologica. 32, p. 13-16

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Intake of Lactobacillus reuteri Improves Incretin and Insulin Secretion in Glucose-Tolerant Humans: A Proof of Concept

    Simon, M., Strassburger, K., Nowotny, B., Kolb, H., Nowotny, P., Burkart, V., Zivehe, F., Hwang, J., Stehle, P., Pacini, G., Hartmann, Bolette, Holst, Jens Juul, MacKenzie, C., Bindels, L. B., Martinez, I., Walter, J., Henrich, B., Schloot, N. C. & Roden, M., 2015, In: Diabetes Care. 38, 10, p. 1827-34 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Integrative Genomics Outlines a Biphasic Glucose Response and a ChREBP-RORγ Axis Regulating Proliferation in β Cells

    Schmidt, S. F., Madsen, J. G. S., Frafjord, K. Ø., Poulsen, L. L. C., Salö, S., Boergesen, M., Loft, A., Larsen, B. D., Madsen, M. S., Holst, Jens Juul, Maechler, P., Dalgaard, L. T. & Mandrup, S., 30 Aug 2016, In: Cell Reports. 16, 9, p. 2359-72 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Interdependency of EGF and GLP-2 Signaling in Attenuating Mucosal Atrophy in a Mouse Model of Parenteral Nutrition

    Feng, Y., Demehri, F. R., Xiao, W., Tsai, Y., Jones, J. C., Brindley, C. D., Threadgill, D. W., Holst, Jens Juul, Hartmann, Bolette, Barrett, T. A., Teitelbaum, D. H. & Dempsey, P. J., May 2017, In: Cellular and Molecular Gastroenterology and Hepatology. 3, 3, p. 447-468 22 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Interleukin-6 Delays Gastric Emptying in Humans with Direct Effects on Glycemic Control

    Lehrskov, L. L., Lyngbaek, M. P., Soederlund, L., Legaard, G. E., Ehses, J. A., Heywood, S. E., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Karstoft, K., Pedersen, Bente Klarlund & Ellingsgaard, H., 2018, In: Cell Metabolism. 27, 6, p. 1201-1211

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Intestinal Adaptation upon Chemotherapy-Induced Intestinal Injury in Mice Depends on GLP-2 Receptor Activation

    Billeschou, Anna, Dal, Jenna Elizabeth Hunt, Ghimire, A., Holst, Jens Juul & Kissow, Hannelouise, 2021, In: Biomedicines. 9, 1, 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Intestinal Growth in Glucagon Receptor Knockout Mice Is Not Associated With the Formation of AOM/DSS-Induced Tumors

    Dal, Jenna Elizabeth Hunt, Yassin, M., Olsen, Jørgen, Hartmann, Bolette, Holst, Jens Juul & Kissow, Hannelouise, 2021, In: Frontiers in Endocrinology. 12, 7 p., 695145.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Intestinal Growth in Glucagon Receptor Knockout Mice is Not Associated with the Formation of Aom/DSS-Induced Tumours

    Dal, Jenna Elizabeth Hunt, Yassin, M., Olsen, Jørgen, Windeløv, Johanne Agerlin, Galsgaard, Katrine Douglas, Holst, Jens Juul & Kissow, Hannelouise, 1 May 2019, In: Gastroenterology. 156, 6 (S1), 1 p., S-692.

    Research output: Contribution to journalConference abstract in journalResearch

  9. Published

    Intestinal adaptation is stimulated by partial enteral nutrition supplemented with the prebiotic short-chain fructooligosaccharide in a neonatal intestinal failure piglet model

    Barnes, J. L., Hartmann, Bolette, Holst, Jens Juul & Tappenden, K. A., Sep 2012, In: Journal of Parenteral and Enteral Nutrition. 36, 5, p. 524-37 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Intestinal growth adaptation and glucagon-like peptide 2 in rats with ileal--jejunal transposition or small bowel resection

    Thulesen, J., Hartmann, Bolette, Kissow, Hannelouise, Jeppesen, Palle Bekker, Ørskov, Cathrine, Holst, Jens Juul & Poulsen, Steen Seier, 2001, In: Digestive Diseases and Sciences. 46, 2, p. 379-88 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Intestinal growth adaptation and glucagon-like peptide 2 in rats with ileal-jejunal transposition or small bowel resection

    Thulesen, J., Hartmann, B., Kissow, H., Jeppesen, P. B., Ørskov, Cathrine, Holst, Jens Juul & Poulsen, Steen Seier, 2001, In: Digestive Diseases and Sciences. 46 (2), p. 379-388

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Intestinal nutrient absorption in newborn pigs in response to enteral nutrition or treatment with glucagon-like peptide 2

    Elnif, J., Buddington, R. K., Petersen, Y. M., Hartmann, B., Holst, Jens Juul, Schmidt, M., Burrin, D. G. & Sangild, Per Torp, 2001, Ikke angivet. Lindberg, J. E., Ogle & B. (eds.). CABI Publishing, p. 37-39 3 p.

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearch

  13. Published

    Intestinal permeability and glucagon-like peptide-2 in children with autism: a controlled pilot study

    Robertson, M. A., Sigalet, D. L., Holst, Jens Juul, Meddings, J. B., Wood, J. & Sharkey, K. A., Jul 2008, In: Journal of Autism and Developmental Disorders. 38, 6, p. 1066-71 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Intestinal permeability and glucagon-like peptide-2 in children with autism: a controlled pilot study

    Robertson, M. A., Sigalet, D. L., Holst, Jens Juul, Meddings, J. B., Wood, J. & Sharkey, K. A., 2008, In: Journal of Autism and Developmental Disorders. 38, 6, p. 1066-1071 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Intestinal sensing and handling of dietary lipids in gastric bypass-operated patients and matched controls

    Martinussen, C., Dirksen, C., Bojsen-Møller, K. N., Svane, M. S., Carlsson, E. R., Hartmann, Bolette, Clausen, T. R., Veedfald, Simon, Kristiansen, V. B., Rehfeld, Jens Frederik, Hansen, Harald S., Holst, Jens Juul & Madsbad, Sten, 2020, In: American Journal of Clinical Nutrition. 111, 1, p. 28-41

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Intravenous glucagon-like peptide 1 (GLP-1) normalizes blood glucose after major surgery in patients with type 2 diabetes

    Meier, J. J., Weyhe, D., Michaely, M., Senkal, M., Zumtobel, V., Nauck, M. A., Holst, Jens Juul, Schmidt, W. E. & Gallwitz, B., 2004, In: Critical Care Medicine. 32, p. 848-851

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Intravenous glucagon-like peptide 1 normalizes blood glucose after major surgery in patients with type 2 diabetes

    Meier, J. J., Weyhe, D., Michaely, M., Senkal, M., Zumtobel, V., Nauck, M. A., Holst, Jens Juul, Schmidt, W. E. & Gallwitz, B., Mar 2004, In: New Horizons (Baltimore). 32, 3, p. 848-51 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Introduction of enteral food increases plasma GLP-2 and decreases GLP-2 receptor mRNA abundance during pig development

    Petersen, Y. M., Hartmann, Bolette, Holst, Jens Juul, Le Huerou-Luron, I., Bjørnvad, Charlotte Reinhard & Sangild, Per Torp, Jun 2003, In: Journal of Nutrition. 133, 6, p. 1781-6 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Introduction of enteral food increases plasma GLP-2 and decreases GLP-2 receptor mRNA abundance during pig development

    Petersen, Y. M., Hartmann, B., Holst, Jens Juul, Le Huërou-Luron, I., Bjørnvad, Charlotte Reinhard & Sangild, Per Torp, 2003, In: Journal of Nutrition. 133, 6, p. 1781-1786 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Investigating Intestinal Glucagon after Roux-en-Y Gastric Bypass Surgery

    Jorsal, T., Wewer Albrechtsen, N. J., Christensen, M. M., Mortensen, B., Wandall, E., Langholz, E., Friis, S., Worm, D., Ørskov, C., Støving, R. K., Andries, A., Juhl, C. B., Sørensen, F., Forman, J. L., Falkenhahn, M., Musholt, P. B., Theis, S., Larsen, P. J., Holst, J. J., Vrang, N. & 3 others, Jelsing, J., Vilsbøll, Tina & Knop, Filip Krag, 2019, In: Journal of Clinical Endocrinology and Metabolism. 104, 12, p. 6403–6416 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published
  22. Published

    Involvement of endogenous glucagon-like peptide-1 in regulation of gastric motility and pancreatic endocrine secretion

    Witte, A., Grybäck, P., Jacobsson, H., Näslund, E., Hellström, P. M., Holst, Jens Juul, Hilsted, Linda & Schmidt, P. T., 2011, In: Scandinavian Journal of Gastroenterology. Supplement. 46, 4, p. 428-35 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Is glucagon‐like peptide‐1 fully protected by the dipeptidyl peptidase 4 inhibitor sitagliptin when administered to patients with type 2 diabetes?

    Andersen, E. S., Lund, A., Bagger, J. I., Andreasen, C., Grøndahl, M., Deacon, Carolyn F., Hartmann, Bolette, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, Aug 2018, In: Diabetes, Obesity and Metabolism. 20, 8, p. 1937-1943

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Is there a place for incretin therapies in obesity and prediabetes?

    Holst, Jens Juul & Deacon, Carolyn F., 13 Feb 2013, In: Trends in Endocrinology and Metabolism. 24, 3, p. 145-152 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Islet-cell dysfunction induced by glucocorticoid treatment: potential role for altered sympathovagal balance?

    van Raalte, D. H., Kwa, K. A. A., van Genugten, R. E., Tushuizen, M. E., Holst, Jens Juul, Deacon, Carolyn F., Karemaker, J. M., Heine, R. J., Mari, A. & Diamant, M., 2013, In: Metabolism. 62, 4, p. 568-577 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Isolated organs as replacements for vertebrate animals

    Holst, Jens Juul, 1994, Handbook of Laboratory Animal Science. USA: CRC Press, p. 397-408

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  27. Published

    Isolation and molecular characterization of porcine calcitonin gene-related peptide (CGRP) and its endocrine effects in the porcine pancreas

    Rasmussen, T. N., Bersani, M., Schmidt, P., Thim, L., Kofod, H., Jørgensen, P. N., Poulsen, Steen Seier & Holst, Jens Juul, Mar 1998, In: Pancreas. 16, 2, p. 195-204 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Jan Fahrenkrug (6/6 1947 – 10/11 2021)

    Rehfeld, Jens Frederik, Hannibal, Jens, Holst, Jens Juul, Hökfelt, T., de Muckadell, O. B. S. & Schwartz, Thue W., 2022, In: Peptides. 150, 170771.

    Research output: Contribution to journalEditorialResearch

  29. Published

    Jejunal feeding is followed by a greater rise in plasma cholecystokinin, peptide YY, glucagon-like peptide 1, and glucagon-like peptide 2 concentrations compared with gastric feeding in vivo in humans: a randomized trial

    Luttikhold, J., van Norren, K., Rijna, H., Buijs, N., Ankersmit, M., Heijboer, A. C., Gootjes, J., Hartmann, Bolette, Holst, Jens Juul, van Loon, L. J. & van Leeuwen, P. A., Feb 2016, In: The American Journal of Clinical Nutrition. 103, 2, p. 435-43 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    KATP channel closure ameliorates the impaired insulinotropic effect of glucose-dependent insulinotropic polypeptide (GIP) in patients with type 2 diabetes

    Aaboe, K., Knop, Filip Krag, Vilsbøll, Tina, Vølund, A., Simonsen, U., Deacon, Carolyn F., Madsbad, Sten, Holst, Jens Juul & Krarup, T., 2009, In: Journal of Clinical Endocrinology and Metabolism. 94, 2, p. 603-608

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    KATP channel closure ameliorates the impaired insulinotropic effect of glucose-dependent insulinotropic polypeptide in patients with type 2 diabetes

    Aaboe, K., Knop, Filip Krag, Vilsboll, T., Vølund, A., Simonsen, U., Deacon, Carolyn F., Madsbad, Sten, Holst, Jens Juul & Krarup, T., 2008, In: Journal of Clinical Endocrinology and Metabolism. 94, 2, p. 603-8 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    KCNQ1 Long QT syndrome patients have hyperinsulinemia and symptomatic hypoglycemia

    Torekov, Signe Sørensen, Iepsen, E., Christiansen, M., Linneberg, Allan René, Pedersen, Oluf Borbye, Holst, Jens Juul, Kanters, Jørgen K. & Hansen, Torben, Apr 2014, In: Diabetes. 63, 4, p. 1315-1325 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    KU bestemmer selv over sin forskning

    Wewer, Ulla M., Holst, Jens Juul, Schwartz, Thue W. & Quistorff, B., 2 Jun 2011, In: Universitetsavisen.

    Research output: Contribution to journalContribution to newspaper - Comment/debateCommunication

  34. Published

    Kardiale virkninger af glukagonlignende peptid 1

    Holst, Jens Juul, 11 Oct 2010, In: Ugeskrift for Laeger. 172, 41, p. 2821 1 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Kirurgisk behandling af type 2-diabetes

    Olesen, S. C., Hansen, D. L., Almdal, Thomas Peter, Bendtsen, Flemming, Nordgaard, I., Hvolris, L. E., Holst, Jens Juul, Naver, L. & Madsbad, Sten, 2009, In: Ugeskrift for læger. 171, 8, p. 615-7 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    L cell secretory responses after gastric bypass surgery can be imitated in un-operated individuals by modulating carbohydrate digestion

    Martinussen, C., Bojsen-Moller, K. N., Dirksen, C., Svane, M. S., Holst, Jens Juul & Madsbad, Sten, 2018, In: Diabetologia. 61, S1, p. S124-S125 244.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  37. Published
  38. Published

    L-glutamine and whole protein restore first-phase insulin response and increase glucagon-like Peptide-1 in type 2 diabetes patients

    Samocha-Bonet, D., Chisholm, D. J., Holst, Jens Juul & Greenfield, J. R., 2015, In: Nutrients. 7, 4, p. 2101-8 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    LEAP2 reduces postprandial glucose excursions and ad libitum food intake in healthy men

    Hagemann, C. A., Jensen, M. S., Holm, Stephanie Kjærulff, Gasbjerg, Lærke Smidt, Byberg, Sarah, Skov-Jeppesen, Kirsa, Hartmann, Bolette, Holst, Jens Juul, Dela, Flemming, Vilsbøll, Tina, Christensen, Mikkel Bring, Holst, Birgitte & Knop, Filip Krag, 2022, In: Cell Reports Medicine. 3, 4, 100582.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Lactobacillus paracasei subsp paracasei L. casei W8 suppresses energy intake acutely

    Bjerg, A. T., Kristensen, M. B., Ritz, C., Holst, Jens Juul, Rasmussen, C., Leser, T. D., Wellejus, A. & Astrup, A., 2014, In: Appetite. 82, p. 111-118 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Leptin Serum Levels are Associated With GLP-1 Receptor Agonist-Mediated Effects on Glucose Metabolism in Clozapine-or Olanzapine-Treated, Prediabetic, Schizophrenia Patients

    Tomasik, J., Rustogi, N., Larsen, J. R., Jakobsen, M. I., Svensson, C. K., Vedtofte, L., Jakobsen, M. S. L., Jespersen, H. R., Koyuncu, K., Schjerning, O., Nielsen, Jimmi, Ekstrøm, Claus Thorn, Correll, C. U., Holst, Jens Juul, Vilsbøll, Tina, Bahn, S. & Fink-Jensen, Anders, 2020, In: Schizophrenia Bulletin Open. 1, 1, 11 p., sgaa044.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Leptin og dens betydning for vægtvedligeholdelse

    Iepsen, E. P. W., Torekov, Signe Sørensen & Holst, Jens Juul, 2012, In: Klinisk biokemi i Norden. 24, 4, p. 8-15 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Linagliptin increases incretin levels, lowers glucagon, and improves glycemic control in type 2 diabetes mellitus

    Rauch, T., Graefe-Mody, U., Deacon, Carolyn F., Ring, A., Holst, Jens Juul, Woerle, H., Dugi, K. A. & Heise, T., Nov 2012, In: Diabetes Therapy. 3, 1, p. 10

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Linagliptin, a selective DPP-4 inhibitor, inhibits DPP-4, increases incretin levels, lowers glucagon, and improves glycaemic control in patients with Type 2 diabetes.

    Rauch, T., Graefe-Mody, U., Deacon, Carolyn F., Ring, A., Holst, Jens Juul, Woerle, H., Dugi, K. & Heise, T., 2012, In: Diabetes Therapy. 3, 1, p. 10

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Linagliptin, a xanthine-based dipeptidyl peptidase-4 inhibitor with an unusual profile for the treatment of type 2 diabetes

    Deacon, Carolyn F. & Holst, Jens Juul, 2010, In: Expert Opinion on Investigational Drugs. 19, 1, p. 133-140 8 p.

    Research output: Contribution to journalReviewResearchpeer-review

  46. Published

    Linagliptin, a xanthine-based dipeptidyl peptidase-4 inhibitor with an unusual profile for the treatment of type 2 diabetes

    Deacon, Carolyn F. & Holst, Jens Juul, Jan 2010, In: Expert Opinion on Investigational Drugs. 19, 1, p. 133-40 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Liraglutide Treatment Is Associated with a Low Frequency and Magnitude of Antibody Formation with No Apparent Impact on Glycemic Response or Increased Frequency of Adverse Events: Results from the Liraglutide Effect and Action in Diabetes (LEAD) trials

    Buse, J. B., Garber, A., Rosenstock, J., Schmidt, W. E., Brett, J. H., Videbæk, N., Holst, Jens Juul & Nauck, M., 2011, In: Journal of Clinical Endocrinology and Metabolism. 96, 6, p. 1695-702 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Liraglutide as adjunct to insulin treatment in type 1 diabetes does not interfere with glycaemic recovery or gastric emptying rate during hypoglycaemia: a randomised, placebo-controlled, double-blind, parallel-group study

    Frandsen, C. S., Dejgaard, T. F., Andersen, H. U., Holst, Jens Juul, Hartmann, Bolette, Thorsteinsson, B. & Madsbad, Sten, 17 Mar 2017, In: Diabetes, Obesity and Metabolism. 19, 6, p. 773-782 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Liraglutide changes postprandial responses of gut hormones involved in the regulation of gallbladder motility

    Nerild, H. H., Brønden, Andreas, Gether, I. M., Hellmann, P. H., Baekdal, M., Gillum, M. P., Svenningsen, J. S., Hartmann, Bolette, Rathor, N., Kudiyanur Muniraju, H. A., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina, Sonne, David Peick & Knop, Filip Krag, 2023, In: Diabetes, Obesity and Metabolism. 25, 6, p. 1632-1637

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Liraglutide decreases postprandial fibroblast growth factor 19 and glucagon-like peptide 2, and increases postprandial cholecystokinin in individuals with obesity

    Bronden, A., Nerild, H. H., Nexoe-Larsen, C. C., Hellmann, P. H., Baekdal, M., Gether, I. M., Gillum, M. P., Hartmann, Bolette, Knudsen, L. B., Jacobsen, L. V., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina, Sonne, D. P. & Knop, Filip Krag, 2021, In: Diabetologia. 64, SUPPL 1, p. 94-94 177.

    Research output: Contribution to journalConference abstract in journalResearch

ID: 4207