Jens Juul Holst

Jens Juul Holst

Professor


  1. Published

    GLP-1 Val8: A Biased GLP-1R Agonist with Altered Binding Kinetics and Impaired Release of Pancreatic Hormones in Rats

    van der Velden, W. J. C., Smit, F. X., Christiansen, Charlotte Bayer, Møller, T. C., Hjortø, Gertrud Malene, Larsen, Olav, Schiellerup, S. P., Bräuner, Hans, Holst, Jens Juul, Hartmann, Bolette, Frimurer, Thomas Michael & Rosenkilde, Mette, 2021, In: ACS Pharmacology & Translational Science. 4, 1, p. 296-313 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    GLP-1 and GIP are colocalized in a subset of endocrine cells in the small intestine

    Mortensen, K., Christensen, L. L., Holst, Jens Juul & Ørskov, Cathrine, 2003, In: Regulatory Peptides. 114, 2-3, p. 189-96 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    GLP-1 and GLP-2 act in concert to inhibit fasted, but not fed, small bowel motility in the rat.

    Bozkurt, A., Näslund, E., Holst, Jens Juul & Hellström, P. M., 2002, In: Regulatory Peptides. 107, 1-3, p. 129-35 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    GLP-1 and Intestinal Diseases

    Dal, Jenna Elizabeth Hunt, Holst, Jens Juul, Jeppesen, Palle Bekker & Kissow, Hannelouise, 2021, In: Biomedicines. 9, 4, 14 p., 383.

    Research output: Contribution to journalReviewResearchpeer-review

  5. Published

    GLP-1 as a Mediator in the Remission of Type 2 Diabetes After Gastric Bypass and Sleeve Gastrectomy Surgery

    Madsbad, Sten & Holst, Jens Juul, Oct 2014, In: Diabetes. 63, 10, p. 3172-4 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    GLP-1 baseret behandling af diabetes og svær overvægt

    Iepsen, E. P. W., Torekov, Signe Sørensen & Holst, Jens Juul, 2015, In: BestPractice. 9, 4, p. 10-12 3 p.

    Research output: Contribution to journalJournal articleCommunication

  7. Published

    GLP-1 defects in diabetes

    Janus, C., Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 2 Feb 2015

    Research output: Other contributionNet publication - Internet publicationResearchpeer-review

  8. Published

    GLP-1 derivatives as novel compounds for the treatment of type 2 diabetes: selection of NN2211 for clinical development

    Knudsen, L. B., Agerso, H., Bjenning, C. & Holst, Jens Juul, 2001, In: Drug Future. 26, p. 677-685

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    GLP-1 does not not acutely affect insulin sensitivity in healthy man

    Orskov, L., Holst, Jens Juul, Møller, J., Ørskov, Cathrine, Møller, N., Alberti, K. G. & Schmitz, O., Oct 1996, In: Diabetologia. 39, 10, p. 1227-32 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    GLP-1 effect on ß-cell function varies according to diabetes remission status after RYGB

    Shah, A., Prasad, M., Mark, V., Holst, Jens Juul & Laferrère, B., 2022, In: Diabetes, Obesity and Metabolism. 24, 11, p. 2081-2089

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    GLP-1 increases microvascular recruitment but not glucose uptake in human and rat skeletal muscle

    Sjøberg, K. A., Holst, Jens Juul, Rattigan, S., Richter, Erik A. & Kiens, Bente, 2014, In: American Journal of Physiology: Endocrinology and Metabolism. 306, 4, p. E355-E362 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    GLP-1 inhibits gastric emptying of water but does not influence plasma vasopressin, sodium, or osmolality

    Naslund, E., Bogefors, J., Gryback, P. & Holst, Jens Juul, 2001, In: Scand J Gastroentero. 36, p. 156-162

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    GLP-1 receptor agonist treatment increases bone formation and prevents bone loss in weight-reduced obese women

    Iepsen, E. P. W., Lundgren, J. R., Hartmann, Bolette, Pedersen, Oluf Borbye, Hansen, Torben, Jørgensen, Niklas Rye, Jensen, J. B., Holst, Jens Juul, Madsbad, Sten & Torekov, Signe Sørensen, 2015, In: The Journal of clinical endocrinology and metabolism. 100, 8, p. 2909 –2917 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    GLP-1 receptor agonists: targeting both hyperglycaemia and disease processes in diabetes

    Holst, Jens Juul & Seino, Y., 2009, In: Diabetes Research and Clinical Practice. 85, 1, p. 1-3 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    GLP-1 receptor argonists for the treatment of diabetes

    Holst, Jens Juul, 2005, In: International Diabetes Monitor. 17, p. 11-18

    Research output: Contribution to journalJournal articleResearch

  16. Published

    GLP-1 responses are heritable and blunted in acquired obesity with high liver fat and insulin resistance

    Matikainen, N., Bogl, L. H., Hakkarainen, A., Lundbom, J., Lundbom, N., Kaprio, J., Rissanen, A., Holst, Jens Juul & Pietiläinen, K. H., Jan 2014, In: Diabetes Care. 37, 1, p. 242-51 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    GLP-1 secretion in acute ischemic stroke: association with functional outcome and comparison with healthy individuals

    Larsson, M., Patrone, C., von Euler, M., Holst, Jens Juul & Nathanson, D., 2019, In: Cardiovascular Diabetology. 18, 8 p., 91.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    GLP-1 suppresses gastrointestinal motility and inhibits the migrating motor complex in healthy subjects and patients with irritable bowel syndrome

    Hellstrom, P. M., Naslund, E., Edholm, T., Schmidt, P. T., Kristensen, J., Theodorsson, E., Holst, Jens Juul & Efendic, S., 2008, In: Neurogastroenterology and Motility. 20, 6, p. 649-659 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    GLP-1 suppresses gastrointestinal motility and inhibits the migrating motor complex in healthy subjects and patients with irritable bowel syndrome

    Hellström, P. M., Näslund, E., Edholm, T., Schmidt, P. T., Kristensen, J., Theodorsson, E., Holst, Jens Juul & Efendic, S., Jun 2008, In: Neurogastroenterology and Motility Online. 20, 6, p. 649-59 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    GLP-1-(9-36) amide reduces blood glucose in anesthetized pigs by a mechanism that does not involve insulin secretion.

    Deacon, Carolyn F., Plamboeck, A., Møller, Søren & Holst, Jens Juul, 2002, In: American Journal of Physiology: Endocrinology and Metabolism. 282, 4, p. E873-9

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    GLP-1-induced renal vasodilation in rodents depends exclusively on the known GLP-1 receptor and is lost in pre-hypertensive rats

    Jensen, E. P., Møller, S., Hviid, A. V. R., Veedfald, Simon, Holst, Jens Juul, Pedersen, Jens, Ørskov, Cathrine & Sorensen, Charlotte Mehlin, 2020, In: American Journal of Physiology: Renal Physiology. 318, 6, p. F1409-F1417

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    GLP-1: physiological effects and potential therapeutic applications

    Aaboe, K., Krarup, T., Madsbad, Sten, Holst, Jens Juul, Aaboe, K., Krarup, T., Madsbad, Sten & Holst, J. J., 2008, In: Diabetic Medicine. 10, 11, p. 994-1003 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    GLP-2 Delays But Does Not Prevent the Onset of Necrotizing Enterocolitis in Preterm Pigs

    Benight, N. M., Stoll, B., Olutoye, O. O., Holst, Jens Juul & Burrin, D. G., 21 Jan 2013, In: Journal of Pediatric Gastroenterology and Nutrition. 56, 6, p. 623-30 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    GLP-2 administration results in increased proliferation but paradoxically an adverse outcome in a juvenile piglet model of short bowel syndrome

    Pereira-Fantini, P. M., Nagy, E. S., Thomas, S. L., Taylor, R. G., Sourial, M., Paris, M. C. J., Holst, Jens Juul, Fuller, P. J. & Bines, J. E., Jan 2008, In: Journal of Pediatric Gastroenterology and Nutrition. 46, 1, p. 20-8 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    GLP-2 administration results in increased proliferation but paradoxically an adverse outcome in a juvenile piglet model of short bowel syndrome

    Pereira-Fantini, P. M., Nagy, T. S., Thomas, S. L., Taylor, R. G., Sourial, M., Paris, M. C. J., Holst, J. J., Fuller, P. J., Bines, J. E. & Holst, Jens Juul, 2008, In: Journal of Pediatric Gastroenterology and Nutrition. 46, 1, p. 20-28 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 4207