Jens Juul Holst

Jens Juul Holst

Professor

ORCID: 0000-0001-6853-3805

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  1. Published

    New Lessons from the gut: Studies of the role of gut peptides in weight loss and diabetes resolution after gastric bypass and sleeve gastrectomy

    Holst, Jens Juul, Madsbad, Sten, Bojsen-Møller, Kirstine Nyvold, Dirksen, C. & Svane, M., 2024, In: Peptides. 176, 9 p., 171199.

    Research output: Contribution to journal › Review › Research › peer-review

  2. Published

    New horizons in diabetes therapy

    Holst, Jens Juul & Deacon, Carolyn F., 2007, In: Immunology, Endocrine and Metabolic Agents in Medicinal Chemistry. 7, 1, p. 49-55 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    New therapies for obesity

    Papamargaritis, D., le Roux, C. W., Holst, Jens Juul & Davies, M. J., 2023, In: Cardiovascular Research. 119, 18, p. 2825–2842

    Research output: Contribution to journal › Review › Research › peer-review

  4. Published

    Nitric oxide (NO) is an important element in neurally induced pancreatic exocrine secretion in pigs

    Holst, Jens Juul, Rasmussen, T. N. & Schmidt, P., 1994, In: Am J Physiology. 29, p. G206-G213

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Nitric oxide has tonic inhibitory effect, but is not involved in the vagal control or VIP effects on motility of the porcine antrum

    Schmidt, P. T., Ørskov, Cathrine, Rasmussen, T. N. & Holst, Jens Juul, Sep 2003, In: Scandinavian Journal of Gastroenterology. 38, 9, p. 955-61 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    No Acute Effects of Exogenous Glucose-Dependent Insulinotropic Polypeptide on Energy Intake, Appetite, or Energy Expenditure When Added to Treatment With a Long-Acting Glucagon-Like Peptide 1 Receptor Agonist in Men With Type 2 Diabetes

    Bergmann, N. C., Gasbjerg, Lærke Smidt, Heimbürger, S. M., Krogh, L. S. L., Dela, Flemming, Hartmann, Bolette, Holst, Jens Juul, Jessen, L., Christensen, Mikkel Bring, Vilsbøll, Tina, Lund, A. & Knop, Filip Krag, 2020, In: Diabetes Care. 43, 3, p. 588-596 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    No Effect of Aprotinin (Trasylol) on Degradation of Exogenous and Endogenous Glucagon in Human, Mouse and Rat Plasma

    Bak, M. J., Albrechtsen, Nicolai Jacob Wewer, Hartmann, Bolette, Pedersen, Jens, Christensen, M., Vilsboll, T., Knop, F. K., Deacon, Carolyn F., Dragsted, Lars Ove & Holst, Jens Juul, 2014, In: Journal of Endocrinology and Diabetes. 1, 1, p. 1-5 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    No Islet Cell Hyperfunction, but Altered Gut-Islet Regulation and Postprandial Hypoglycemia in Glucose-Tolerant Patients 3 Years After Gastric Bypass Surgery

    Dirksen, C., Eiken, A., Bojsen-Møller, K. N., Svane, M. S., Martinussen, C., Jørgensen, N. B., Holst, Jens Juul & Madsbad, Sten, Sep 2016, In: Obesity Surgery. 26, 9, p. 2263-7 5 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  9. Published

    No changes in levels of bone formation and resorption markers following a broad-spectrum antibiotic course

    Mikkelsen, K. H., Vilsbøll, Tina, Holst, Jens Juul, Hartmann, Bolette, Knop, Filip Krag & Frost, M., 2018, In: BMC Endocrine Disorders. 18, 6 p., 60.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    No detectable effect of a type 2 diabetes-associated TCF7L2 genotype on the incretin effect

    Mathiesen, D. S., Bagger, J., Hansen, K. B., Junker, A. E., Plamboeck, A., Harring, S., Idorn, T., Hornum, M., Holst, Jens Juul, Jonsson, Anna Elisabet, Hansen, Torben, Vilsbøll, Tina, Lund, Asger Bach & Knop, Filip Krag, 2020, In: Endocrine Connections. 9, 12, p. 1221-1232 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    No direct effect of SGLT2 activity on glucagon secretion

    Kuhre, Rune Ehrenreich, Ghiasi, S. M., Adriaenssens, A. E., Albrechtsen, Nicolai Jacob Wewer, Andersen, Daniel Bjørklund, Aivazidis, A., Chen, L., Mandrup-Poulsen, Thomas, Ørskov, Cathrine, Gribble, F. M., Reimann, F., Wierup, N., Tyrberg, B. & Holst, Jens Juul, 2019, In: Diabetologia. 62, 6, p. 1011-1023

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    No effect of physiological concentrations of glucagon-like peptide-2 on appetite and energy intake in normal weight subjects

    Sørensen, L. B., Flint, A., Raben, Anne, Hartmann, Bolette, Holst, Jens Juul & Astrup, A., Apr 2003, In: International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity. 27, 4, p. 450-6 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    No effect of physiological concentrations of glucagon-like peptide-2 on appetite and energy intake in normal weight subjects

    Sørensen, L. B., Flint, A., Raben, A. B., Hartmann, B., Holst, Jens Juul & Astrup, A., 2003, In: International Journal of Obesity. 27, 4, p. 450-456 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    No effect of the turmeric root phenol curcumin on prednisolone-induced gluco-metabolic perturbations in men with overweight or obesity

    Hellmann, P. H., Bagger, J. I., Carlander, K. R., Hansen, K. B., Forman, Julie Lyng, Størling, Joachim, Chabanova, E., Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2023, In: Endocrine Connections. 12, 4, e220334.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    No effects of a 6-week intervention with a glucagon-like peptide-1 receptor agonist on pancreatic volume and oedema in obese men without diabetes

    Svane, M. S., Johannesen, Helle Hjorth, Martinussen, C., Bojsen-Moller, K. N., Hansen, M. L., Hansen, Adam Espe, Deacon, Carolyn F., Hartmann, Bolette, Keller, S. H., Klausen, T. L., Loft, A., Kjær, Andreas, Madsbad, Sten, Lofgren, J., Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2020, In: Diabetes, Obesity and Metabolism. 22, 10, p. 1837-1846

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    No effects of dapagliflozin, metformin or exercise on plasma glucagon concentrations in individuals with prediabetes: A post hoc analysis from the randomized controlled PRE-D trial

    Clemmensen, K. K. B., Blond, M. B., Amadid, H., Bruhn, L., Vistisen, D., Karstoft, K., Persson, F., Ried-Larsen, M., Holst, Jens Juul, Albrechtsen, Nicolai Jacob Wewer, Torekov, Signe Sørensen, Quist, J. S., Jorgensen, M. E. & Faerch, K., 2021, In: Diabetes, Obesity and Metabolism. 23, 2, p. 530-539

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    No evidence of tachyphylaxis for insulinotropic actions of glucose-dependent insulinotropic polypeptide (GIP) in subjects with type 2 diabetes, their first-degree relatives, or in healthy subjects

    Nauck, M. A., Holle, H., Kahle, M., Tytko, A., Deacon, Carolyn F., Holst, Jens Juul & Meier, J. J., 2020, In: Peptides. 125, 170176.

    Research output: Contribution to journal › Review › Research › peer-review

  18. Published

    No increased risk of hypoglycaemic episodes during 48 h of subcutaneous glucagon-like-peptide-1 administration in fasting healthy subjects

    Lerche, S., Soendergaard, L., Rungby, J., Moeller, N., Holst, Jens Juul, Schmitz, O. E. & Brock, B., 2008, In: Clinical Endocrinology. 71, 4, p. 500-6 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    No reactive hypoglycaemia after subcutaneous administrations of GLP-1 in lean type 2 diabetic patients and in patients with diabeties secondary to chronic pancreatitis

    Knop, F., Vilsbøll, T., Larsen, S., Holst, Jens Juul & Krarup, T., 2003, In: Diabetes Care. 26, p. 2581-2587

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    No reactive hypoglycaemia in type 2 diabetic patients after subcutaneous administration of GLP-1 and intravenous glucose

    Vilsbøll, Tina, Krarup, T., Madsbad, Sten & Holst, Jens Juul, 1 Feb 2001, In: Diabetic Medicine. 18, 2, p. 144-149 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Non-insulin pharmacological therapies for treating type 1 diabetes

    Frandsen, C. S., Dejgaard, T. F., Madsbad, Sten & Holst, Jens Juul, 2018, In: Expert Opinion on Pharmacotherapy. 19, 9, p. 947-960

    Research output: Contribution to journal › Review › Research › peer-review

  22. Published

    Non-insulin-dependent diabetes mellitus - new drugs?

    Holst, Jens Juul, 1997, In: Drug Discovery Today. 2, p. 128-129

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Nonalcoholic Fatty Liver Disease Impairs the Liver-Alpha Cell Axis Independent of Hepatic Inflammation and Fibrosis

    Pedersen, J. S., Rygg, M. O., Kristiansen, V. B., Olsen, B. H., Serizawa, R. R., Holst, Jens Juul, Madsbad, Sten, Gluud, Lise Lotte, Bendtsen, Flemming & Albrechtsen, Nicolai Jacob Wewer, 2020, In: Hepatology Communications. 4, 11, p. 1610-1623 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Nonalcoholic Fatty Liver Disease Is Prevalent in Women With Prior Gestational Diabetes Mellitus and Independently Associated With Insulin Resistance and Waist Circumference

    Foghsgaard, S., Andreasen, C., Vedtofte, L., Andersen, E. S., Bahne, E., Strandberg, C., Buhl, T., Holst, Jens Juul, Svare, J. A., Clausen, Tine Dalsgaard, Mathiesen, Elisabeth, Damm, Peter, Gluud, Lise Lotte, Knop, Filip Krag & Vilsbøll, Tina, Jan 2017, In: Diabetes Care. 40, 1, p. 109-116 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Normal insulin sensitivity, glucose tolerance, gut incretin and pancreatic hormone responses in adults with atopic dermatitis

    Gether, L., Thyssen, Jacob Pontoppidan, Gyldenlove, M., Hartmann, Bolette, Holst, Jens Juul, Foghsgaard, S., Vilsbøll, Tina & Knop, Filip Krag, 2020, In: Diabetes, Obesity and Metabolism. 22, 11, p. 2161-2169 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Normal physical activity obliterates the deleterious effects of high-caloric intake

    Krogh-Madsen, Rikke, Pedersen, M., Solomon, T., Knudsen, S. H., Hansen, L. S., Karstoft, K., Lehrskov-Schmidt, L., Pedersen, K. K., Thomsen, C., Holst, Jens Juul & Pedersen, Bente Klarlund, 7 Nov 2013, In: Journal of Applied Physiology. 116, 3, p. 231-239 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Normal secretion and action of the gut incretin hormones glucagon-like peptide-1 and glucose-dependent insulinotropic polypeptide in young men with low birth weight

    Schou, J. H., Pilgaard, K., Vilsbøll, Tina, Jensen, C. B., Deacon, Carolyn F., Holst, Jens Juul, Vølund, A., Madsbad, Sten & Vaag, Allan, 2005, In: Journal of Clinical Endocrinology and Metabolism. 90, 8, p. 4912-19 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Normal secretion of the incretin hormones glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 during gestational diabetes mellitus

    Cypryk, K., Vilsbøll, Tina, Nadel, I., Smyczynska, J., Holst, Jens Juul & Lewinski, A., 2007, In: Gynecological Endocrinology. 23, 1, p. 58-62 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Normalisation of glucose concentrations and deceleration of gastric emptying of solid meals during intravenous glucagon-like peptide-1 (GLP-1) in patients with type 2 diabetes

    Meier, J. J., Gallwitz, B., Salmen, S., Goetze, O., Holst, Jens Juul & Schmidt, W. E., 2003, In: J. Clin. Endocrinol. Metab.. 88, p. 2719-2725

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Normalization of fasting glycaemia by intravenous GLP-1 ([7-36 amide] or [7-37]) in type 2 diabetic patients

    Nauck, M. A., Weber, I., Bach, I., Richter, S., Ørskov, Cathrine, Holst, Jens Juul & Schmiegel, W., Nov 1998, In: Diabetic Medicine Online. 15, 11, p. 937-45 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Normalization of fasting hyperglycaemia by exogenous-glucagon-like peptide 1 (7-36 amide) in type 2 (non-insulin-dependent) diabetic patients

    Nauck, M. A., Kleine, N., Ørskov, C., Holst, Jens Juul, Willms, B. & Creutzfeldt, W., 1993, In: Diabetologia. 36, p. 741-744

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Normalization of glucose concentrations and deceleration of gastric emptying after solid meals during intravenous glucagon-like peptide 1 in patients with type 2 diabetes

    Meier, J. J., Gallwitz, B., Salmen, S., Goetze, O., Holst, Jens Juul, Schmidt, W. E. & Nauck, M. A., Jun 2003, In: The Journal of clinical endocrinology and metabolism. 88, 6, p. 2719-25 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Normalization of sting glycemia by intravenous GLP-1 (7-36amide) or (7-37) in Type 2 diabetic patients

    Nauck, M. A., Weber, I., Bach, I., Richter, S. H., Ørskov, C., Holst, Jens Juul & Schmiegel, W., 1998, In: Diabetic Medicine. 15, p. 937-945

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Novel Mody3 Mutations in the Hepatocyte Factor-1a Gene. Evidence for a Hyperexcitabillity of Pancreatic ß-cells to Intravenous Secretagogues in a Glucosetolerant Carrier of a P447L Mutation

    Hansen, T., Eiberg, Hans Rudolf Lytchoff, Rouard, M., Vaxillaire, M., Møller, A. M., Rasmussen, S. K., Fridberg, M. & Holst, Jens Juul, 1997, In: Diabetes. 46, p. 726-730

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Novel agonist- and antagonist-based radioligands for the GLP-2 receptor - useful tools for studies of basic GLP-2R pharmacology

    Gadgaard, S., van der Velden, W. J. C., Schiellerup, S. P., Dal, Jenna Elizabeth Hunt, Gabe, M. B. N., Windeløv, Johanne Agerlin, Boer, G. A., Kissow, Hannelouise, Ørskov, Cathrine, Holst, Jens Juul, Hartmann, Bolette & Rosenkilde, M. M., 2022, In: British Journal of Pharmacology. 179, 9, p. 1998-2015

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Nutrient Restriction has Limited Short-Term Effects on Gut, Immunity, and Brain Development in Preterm Pigs

    Ahnfeldt, Agnethe May, Bæk, Ole, Hui, Y., Nielsen, Charlotte Holme, Obelitz-Ryom, K., Busk-Anderson, T., Ruge, A., Holst, Jens Juul, Rudloff, S., Burrin, D., Nguyen, Duc Ninh, Nielsen, Dennis Sandris, Zachariassen, G., Bering, S. B., Thymann, Thomas & Sangild, Per Torp, 2020, In: The Journal of Nutrition. 150, 5, p. 1196-1207

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Nutrient re-routing and altered gut-islet cell crosstalk may explain early relief of severe postprandial hypoglycaemia after reversal of Roux-en-Y gastric bypass

    Svane, M. S., Toft-Nielsen, M. B., Kristiansen, V. B., Hartmann, Bolette, Holst, Jens Juul, Madsbad, Sten & Bojsen-Møller, K. N., Dec 2017, In: Diabetic Medicine Online. 34, 12, p. 1783-1787

    Research output: Contribution to journal › Letter › Research › peer-review

  38. Published

    Nutrient-stimulated GLP-2 release and crypt cell proliferation in experimental short bowel syndrome

    Martin, G. R., Wallace, L. E., Hartmann, Bolette, Holst, Jens Juul, Demchyshyn, L., Toney, K. & Sigalet, D. L., Mar 2005, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 288, 3, p. G431-8

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Nutrients of animal origin and function of gut hormones

    Holst, Jens Juul, 1998, Food and Health: Role of Animal Products. Paris: Elsevier, p. 13-22

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  40. Published

    Nutritional effects of the serial transverse enteroplasty procedure in experimental short bowel syndrome

    Kaji, T., Tanaka, H., Wallace, L. E., Kravarusic, D., Holst, Jens Juul & Sigalet, D. L., 2009, In: European Journal of Pediatric Surgery. Supplement. 44, 8, p. 1552-9 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Obesity - an indication for GLP-1 treatment? Obesity pathophysiology and GLP-1 treatment potential

    Torekov, Signe Sørensen, Madsbad, Sten & Holst, Jens Juul, 2011, In: Obesity Reviews. 12, 8, p. 593-601 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Obesity - did anything happen since leptin?

    Holst, Jens Juul, 1998, In: Ugeskrift for læger. 160, p. 1182-1184

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Occurrence, distribution and motor effects of galanin in the porcine lower esophageal sphincter

    Holst, Jens Juul & Poulsen, Steen Seier, 1989, In: Digestion. 42, 3, p. 151-7 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Octreotide suppresses the incretin GLP-1 in patients with acromegally, clinically nonfunctioning pituitary tumours and in healthy subjects

    Plöckinger, U., Holst, Jens Juul, Messerschmidt, D., Hopfenmüller, W. & Quabbe, H. J., 1999, In: European Journal of Endocrinology. 140, p. 538-544

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Older subjects with β-cell dysfunction have an accentuated incretin release

    De Jesús Garduno-Garcia, J., Gastaldelli, A., DeFronzo, R. A., Lertwattanarak, R., Holst, Jens Juul & Musi, N., 2018, In: Journal of Clinical Endocrinology and Metabolism. 103, 7, p. 2613-2619 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    On measurements of glucagon secretion in healthy, obese, and Roux-en-Y gastric bypass operated individuals using sandwich ELISA

    Albrechtsen, Nicolai Jacob Wewer, Kjeldsen, Sasha Alexandra Sampson, Jensen, N. J., Rungby, Jørgen, Veedfald, Simon, Bojsen-Møller, K. N., Dirksen, C., Jensen, Christian Zinck, Martinussen, C., Madsbad, Sten & Holst, Jens Juul, 2022, In: Scandinavian Journal of Clinical & Laboratory Investigation. 82, 1, p. 75-83

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    On the effects of glucagon-like peptide-1 on blood glucose regulation in normal and diabetic subjects

    Holst, Jens Juul, Toft-Nielsen, M. B., Ørskov, Cathrine, Nauck, M. & Willms, B., 26 Dec 1996, In: Annals of the New York Academy of Sciences. 805, p. 729-36 8 p.

    Research output: Contribution to journal › Review › Research › peer-review

  48. Published

    On the effects of human galanin in man

    Holst, Jens Juul, Bersani, M., Hvidberg, A., Knigge, Ulrich, Christiansen, E. M., Madsbad, Sten, Harling, H. & Kofod, H., 1993, In: Diabetologia. 36, 7, p. 653-657 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    On the physiology of GIP and GLP-1

    Holst, Jens Juul, 19 Jan 2005, In: Hormone and Metabolic Research. Supplement. 36, 11-12, p. 747-54 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    On the physiology of GIP and GLP-1

    Holst, Jens Juul, 2004, In: Horm Metab Res. 36, p. 747-754

    Research output: Contribution to journal › Journal article › Research › peer-review

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