Jens Juul Holst

Jens Juul Holst

Professor

ORCID: 0000-0001-6853-3805

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  1. Published

    On the regulatory functions of neuropeptide Y (NPY) with respect to vascular resistance and exocrine and endocrine secretion in the pig pancreas

    Holst, Jens Juul, Ørskov, Cathrine, Knuhtsen, S., Sheikh, S. & Nielsen, O. V., Aug 1989, In: Acta Physiologica Scandinavica. 136, 4, p. 519-26 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    On the relationship between glucose absorption and glucose‐stimulated secretion of GLP‐1, neurotensin, and PYY from different intestinal segments in the rat

    Kuhre, Rune Ehrenreich, Christiansen, Charlotte Bayer, Saltiel, M. Y., Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 3 Dec 2017, In: Physiological Reports. 5, 23, 13 p., e13507.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    On the role of gallbladder emptying and incretin hormones for nutrient-mediated TSH suppression in patients with type 2 diabetes

    Sonne, David Peick, Lund, Asger Bach, Faber, J., Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, Dec 2014, In: Endocrine Connections. 3, 4, p. 193-9 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    On the role of glucose-dependent insulintropic polypeptide in postprandial metabolism in humans

    Asmar, M., Tangaa, W., Madsbad, Sten, Hare, K., Astrup, A., Flint, A., Bülow, J. & Holst, Jens Juul, 2010, In: American Journal of Physiology: Endocrinology and Metabolism. 298, 3, p. E614-21 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    On the treatment of diabetes mellitus with glucagon-like peptide-1.

    Holst, Jens Juul, Deacon, Carolyn F., Toft-Nielsen, M. & Bjerre-Knudsen, L., 1998, In: Annals of the New York Academy of Sciences. 865, p. 336-343

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    One Year's Treatment with the Glucagon-Like Peptide 1 Receptor Agonist Liraglutide Decreases Hepatic Fat Content in Women with Nonalcoholic Fatty Liver Disease and Prior Gestational Diabetes Mellitus in a Randomized, Placebo-Controlled Trial

    Vedtofte, L., Bahne, E., Foghsgaard, S., Bagger, J. I., Andreasen, C., Strandberg, C., Gortz, P. M., Holst, Jens Juul, Gronbaek, H., Svare, J. A., Clausen, Tine Dalsgaard, Mathiesen, Elisabeth, Damm, Peter, Gluud, Lise Lotte, Knop, Filip Krag & Vilsbøll, Tina, 2020, In: Journal of Clinical Medicine. 9, 10, 14 p., 3213.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Onset of small intestinal atrophy is associated with reduced intestinal blod flow in TNP-fed neonatal piglets

    Niinikoski, H., Stoll, B., Guam, X., Kansagra, K., Lambert, B., Hartmann, B., Holst, Jens Juul & Burrin, D. G., 2004, In: Journal of Nutrition. 134, p. 1467-1474

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Onset of small intestinal atrophy is associated with reduced intestinal blood flow in TPN-fed neonatal piglets

    Niinikoski, H., Stoll, B., Guan, X., Kansagra, K., Lambert, B. D., Stephens, J., Hartmann, Bolette, Holst, Jens Juul & Burrin, D. G., Jun 2004, In: Journal of Nutrition. 134, 6, p. 1467-74 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Opposing effects of chronic glucagon receptor agonism and antagonism on amino acids, hepatic gene expression, and alpha cells

    Elmelund, E., Galsgaard, Katrine Douglas, Johansen, C. D., Trammell, Sam, Billeschou, Anna, Winther-Sørensen, Marie, Dal, Jenna Elizabeth Hunt, Sorensen, Charlotte Mehlin, Kruse, Thomas, Lau, J. F., Grevengoed, Trisha Jean, Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2022, In: iScience. 25, 11, 20 p., 105296.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Opposing roles of the entero-pancreatic hormone urocortin-3 in glucose metabolism in rats

    Grunddal, Kaare Villum, Trammell, Sam, Bæch-Laursen, C., Andersen, Daniel Bjørklund, Xu, S. F. S., Andersen, H., Gillum, M. P., Ghiasi, S. M., Novak, Ivana, Tyrberg, B., Li, C., Rosenkilde, Mette, Hartmann, Bolette, Holst, Jens Juul & Kuhre, Rune Ehrenreich, 2022, In: Diabetologia. 65, p. 1018–1031

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Oral 2-oleyl glyceryl ether improves glucose tolerance in mice through the GPR119 receptor

    Hassing, H. A., Engelstoft, M. S., Sichlau, R. M., Madsen, A. N., Rehfeld, Jens Frederik, Pedersen, Jens, Jones, R. M., Holst, Jens Juul, Schwartz, Thue W., Rosenkilde, Mette & Hansen, Harald S., 2016, In: BioFactors. 42, 6, p. 665-673

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Oral D/L-3-Hydroxybutyrate Stimulates Cholecystokinin and Insulin Secretion and Slows Gastric Emptying in Healthy Males

    Rittig, N., Svart, M., Thomsen, H. H., Vestergaard, E. T., Rehfeld, Jens Frederik, Hartmann, Bolette, Holst, Jens Juul, Johannsen, M., Møller, N. & Jessen, N., 2020, In: Journal of Clinical Endocrinology and Metabolism. 105, 10, 9 p., dgaa483.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Oral glucose has little or no effect on appetite and satiety sensations despite a significant gastrointestinal response

    Lauritsen, J. V., Bergmann, N., Junker, A. E., Gyldenløve, Mette, Skov, Lone, Gluud, Lise Lotte, Hartmann, Bolette, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 2023, In: European Journal of Endocrinology. 189, 6, p. 619-626 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Oral glutamine increases circulating glucagon-like peptide 1, glucagon, and insulin concentrations in lean, obese, and type 2 diabetic subjects

    Greenfield, J. R., Farooqi, I. S., Keogh, J. M., Henning, E., Habib, A. M., Blackwood, A., Reimann, F., Holst, Jens Juul & Gribble, F. M., 2008, In: American Journal of Clinical Nutrition. 89, 1, p. 106-13 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Orlistat accelerates gastric emptying and attenuates GIP release in healthy subjects

    Enç, F. Y., Ones, T., Akin, H. L., Dede, F., Turoglu, H. T., Ulfer, G., Bekiroglu, N., Haklar, G., Rehfeld, Jens Frederik, Holst, Jens Juul, Ulusoy, N. B. & Imeryüz, N., 2008, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 296, 3, p. G482-9

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Orlistat inhibition of intestinal lipase acutely increases appetite and attenuates postprandial glucagon-like peptide-1-(7-36)-amide-1, cholecystokinin, and peptide YY concentrations

    Ellrichmann, M., Kapelle, M., Ritter, P. R., Holst, Jens Juul, Herzig, K. H., Schmidt, W. E., Schmitz, F. & Meier, J. J., 2008, In: Journal of Clinical Endocrinology and Metabolism. 93, 10, p. 3995-3998 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Orlistat inhibition of intestinal lipase acutely increases appetite and attenuates postprandial glucagon-like peptide-1-(7-36)-amide-1, cholecystokinin, and peptide YY concentrations

    Ellrichmann, M., Kapelle, M., Ritter, P. R., Holst, Jens Juul, Herzig, K., Schmidt, W. E., Schmitz, F. & Meier, J. J., Oct 2008, In: The Journal of clinical endocrinology and metabolism. 93, 10, p. 3995-8 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Overconsumption and obesity: peptides and susceptibility to weight gain

    Blundell, J. E., Levin, F., King, N. A., Barkeling, B., Gustafsson, T., Gustafson, T., Hellstrom, P. M., Holst, Jens Juul & Naslund, E., 7 Aug 2008, In: Regulatory Peptides. 149, 1-3, p. 32-8 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Overconsumption and obesity: Peptides and susceptibility to weight gain

    Blundell, J. E., Levin, F., King, N. A., Barkeling, B., Gustafson, T., Hellstrom, P. M., Holst, Jens Juul & Naslund, E., 2008, In: Regulatory Peptides. 149, 1-3, p. 32-38 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Overnight GLP-1 normalizes fasting but not daytime plasma glucose levels in NIDDM patients

    Willms, B., Idowu, K., Holst, Jens Juul, Creutzfeldt, W. & Nauck, M. A., 1998, In: Exp. Clin. Endocrinol. Diabetes. 106, p. 103-107

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Overview of incretin hormones.

    Holst, Jens Juul & Lasalle, J., 2008, In: Journal of Family Practice. 57, 9, p. 53-59

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Oxidation/reduction explains heterogeneity of pancreatic somatostatin

    Bersani, M., Johnsen, A. H. & Holst, Jens Juul, 1991, In: FEBS Letter. 279, no.2, p. 237-239

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Oxyntomodulin: actions and role in diabetes

    Holst, Jens Juul, Albrechtsen, Nicolai Jacob Wewer, Gabe, M. B. N. & Rosenkilde, M. M., 2018, In: Peptides. 100, p. 48-53 6 p.

    Research output: Contribution to journal › Review › Research › peer-review

  24. Published

    Oxyntomodulin Identified as a Marker of Type 2 Diabetes and Gastric Bypass Surgery by Mass-spectrometry Based Profiling of Human Plasma

    Albrechtsen, Nicolai Jacob Wewer, Hornburg, D., Albrechtsen, Reidar, Svendsen, B., Toräng, S., Jepsen, Sara Lind, Kuhre, Rune Ehrenreich, Hansen, M., Janus, C., Floyd, A., Lund, Asger Bach, Vilsbøll, Tina, Knop, Filip Krag, drb459, drb459, Deacon, Carolyn F., Meissner, F., Mann, Matthias, Holst, Jens Juul & Hartmann, Bolette, May 2016, In: EBioMedicine. 7, p. 112-120 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Oxyntomodulin and glicentin may predict the effect of bariatric surgery on food preferences and weight loss

    Nielsen, M. S., Ritz, C., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, le Roux, C. W. & Sjödin, Anders Mikael, 2020, In: Journal of Clinical Endocrinology and Metabolism. 105, 4, p. e1064-e1074

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    PACAP 1-38 as neurotransmitter in porcine adrenal glands

    Tornøe, K., Hannibal, J., Rickelt, L. F., Bolding Jensen, M., Børglum, J. T., Fahrenkrug, J. & Holst, Jens Juul, 2000, In: American Journal of Physiology: Endocrinology and Metabolism. 279, p. E1412-E1425

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    PACAP 1-38 as neurotransmitter in the pig pancreas: PACAP-receptor activation revealed by the antagonist PACAP 6-38.

    Tornøe, K., Hannibal, J., Fahrenkrug, J. & Holst, Jens Juul, 1997, In: Am. J. Physiol.. 273, p. G436-G446

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    PACAP 1-38 as neurotransmitter in the porcine antrum

    Tornoe, K., Hannibal, J., Georg, B. & Holst, Jens Juul, 2001, In: Regulatory Peptides. 101, p. 109-121

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    PACAP contributes to insulin secretion after gastric glucose gavage in mice

    Filipsson, K., Holst, Jens Juul & Ahrén, B., 2000, In: Am. J. Physiol.. 279, p. R424-432

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Pancreas and gut hormone responses to oral glucose and intravenous glucagon in cystic fibrosis patients with normal, impaired and diabetic glucose tolerance

    Laang, S., Thorsteinsson, B., Røder, M. E., Ørskov, Cathrine, Holst, Jens Juul, Nerup, J. & Koch, C., 1993, In: Acta Endoctrinologica. 128, p. 207-214

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Pancreatic Polypeptide in Parkinson's Disease: A Potential Marker of Parasympathetic Denervation

    Knudsen, K., Hartmann, Bolette, Fedorova, T. D., Østergaard, K., Krogh, K., Møller, N., Holst, Jens Juul & Borghammer, P., 2017, In: Journal of Parkinson's Disease. 7, 4, p. 645-652 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Pancreatic and Intestinal Function Post Roux-en-Y Gastric Bypass Surgery for Obesity

    O'Keefe, S. J. D., Rakitt, T., Ou, J., El Hajj, I. I., Blaney, E., Vipperla, K., Holst, Jens Juul & Rehlfeld, J., 3 Aug 2017, In: Clinical and Translational Gastroenterology. 8, 11 p., e112.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Pancreatic and intestinal processing of proglucagon in man

    Holst, Jens Juul & Poulsen, Steen Seier, Nov 1987, In: Diabetologia. 30, 11, p. 874-81 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Pancreatic beta-cell overexpression of the glucagon receptor gene results in enhanced beta-cell function and mass

    Gelling, R. W., Vuguin, P. M., Du, X. Q., Cui, L., Rømer, J., Pederson, R. A., Leiser, M., Sørensen, H., Holst, Jens Juul, Fledelius, C., Johansen, P. B., Fleischer, N., McIntosh, C. H. S., Nishimura, E. & Charron, M. J., 2009, In: American Journal of Physiology: Endocrinology and Metabolism. 297, 3, p. E695-707

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Pancreatic beta-cell responses to GLP-1 after near-normalization of blood glucose in patients with type 2 diabetes

    Asmar, M., Højberg, P. V., Deacon, Carolyn F., Hare, K., Holst, Jens Juul & Madsbad, Sten, 2010, In: Regulatory Peptides. 160, 1-3, p. 175-80 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Pancreatic effects of GLP-1

    Kuhre, Rune Ehrenreich, Albrechtsen, Nicolai Jacob Wewer & Holst, Jens Juul, 22 Dec 2014, Diapedia: The Living Textbook of Diabetes. European Association for the Study of Diabetes (EASD)

    Research output: Chapter in Book/Report/Conference proceeding › Encyclopedia chapter › Communication

  37. Published

    Pancreatic polypeptide: A potential biomarker of glucose-dependent insulinotropic polypeptide receptor activation in vivo

    Veedfald, Simon, Bergmann, N. C., Vilsbøll, Tina, Christensen, Mikkel Bring, Holst, Jens Juul & Knop, Filip Krag, May 2021, In: Diabetic Medicine Online. 38, 8, e14592.

    Research output: Contribution to journal › Letter › Research › peer-review

  38. Published

    Pancreatic polypeptide responses to isoglycemic oral and intravenous glucose in humans with and without intact vagal innervation

    Veedfald, Simon, Plamboeck, A., Hartmann, Bolette, Svendsen, Lars Bo, Vilsbøll, T., Knop, Filip Krag & Holst, Jens Juul, Sep 2015, In: Peptides. 71, p. 229-31 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Pancreatic safety of GLP-1-based therapeutic agents: further insights from rodent studies?

    Holst, Jens Juul, Sep 2013, In: Diabetologia. 56, 9, p. 1869-72 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Pancreatic ß-cell responses to GLP-1 after near-normalization of blood glucose in patients with type 2 diabetes

    Asmar, M., Højberg, P., Deacon, Carolyn F., Hare, K., Holst, Jens Juul & Madsbad, Sten, 2010, In: Regulatory Peptides. 160, 1-3, p. 175-180 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Pancreatic α-cell hyperplasia and hyperglucagonemia due to a mutation of the glucagon

    Larger, E., Albrechtsen, Nicolai Jacob Wewer, Hansen, L. H., Gelling, R. W., Capeau, J., Deacon, Carolyn F., Madsen, O. D., Yakushiji, F., Meyts, P. D., Holst, Jens Juul & Nishimura, E., 2016, In: Endocrinology, Diabetes & Metabolism Case Reports. 2016, 6 p., EDM160081.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Paracrine Crosstalk between Intestinal L- and D-cells Controls Secretion of Glucagon-Like Peptide-1 in mice

    Jepsen, Sara Lind, Grunddal, Kaare Villum, Albrechtsen, Nicolai Jacob Wewer, Engelstoft, M. S., Gabe, M. B. N., Jensen, E. P., Ørskov, Cathrine, Poulsen, Steen Seier, Rosenkilde, M. M., Pedersen, J., Gribble, F. M., Reimann, F., Deacon, Carolyn F., Schwartz, Thue W., Christ, A. D., Martin, R. E. & Holst, Jens Juul, 2019, In: American Journal of Physiology: Endocrinology and Metabolism. 317, 6, p. E1081-E1093

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Paracrine regulation of somatostatin secretion by insulin and glucagon in mouse pancreatic islets

    Svendsen, B. & Holst, Jens Juul, 2021, In: Diabetologia. 64, p. 142–151 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Parenteral nutrition impairs plasma bile acid and gut hormone responses to mixed meal testing in lean healthy men

    Meessen, E. C. E., Bakker, G. J., Nieuwdorp, M., Dallinga-Thie, G. M., Kemper, E. M., Olde Damink, S. W., Romijn, J. A., Hartmann, Bolette, Holst, Jens Juul, Knop, Filip Krag, Groen, A. K., Schaap, F. G. & Soeters, M. R., 2021, In: Clinical Nutrition. 40, 3, p. 1013-1021

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Pathophysiology and aetiology of impaired fasting glycaemia and impaired glucose tolerance: does it matter for prevention and treatment of type 2 diabetes?

    Faerch, K., Borch-Johnsen, K., Holst, Jens Juul & Vaag, Allan, 2009, In: Diabetologia. 52, 9, p. 1714-23 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Patient profiling for success after weight loss surgery (GO Bypass study): An interdisciplinary study protocol

    Christensen, Bodil Just, Schmidt, J. B., Nielsen, M. S., Tækker, L., Holm, Lotte, Lunn, Susanne, Bredie, Wender, Ritz, C., Holst, Jens Juul, Hansen, Torben, Hilbert, A., le Roux, C. W., Hulme, O. J., Siebner, Hartwig Roman, Morville, T., Naver, L., Floyd, A. K. & Sjödin, Anders Mikael, 2018, In: Contemporary Clinical Trials Communications. 10, p. 121-130 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Patients with Long QT Syndrome Due to Impaired hERG-encoded Kv11.1 Potassium Channel Have Exaggerated Endocrine Pancreatic and Incretin Function Associated with Reactive Hypoglycemia

    Hyltén-Cavallius, L., Iepsen, E. W., Albrechtsen, Nicolai Jacob Wewer, Svendstrup, M., Lubberding, Anniek Frederike, Hartmann, Bolette, Jespersen, Thomas, Linneberg, Allan René, Christiansen, M., drb459, drb459, Pedersen, Oluf Borbye, Holst, Jens Juul, Kanters, Jørgen K., Hansen, Torben & Torekov, Signe Sørensen, 2017, In: Circulation. 135, 18, p. 1705-1719 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Patients with Obesity Caused by Melanocortin-4 Receptor Mutations Can Be Treated with a Glucagon-like Peptide-1 Receptor Agonist

    Iepsen, E. W., Zhang, J., Thomsen, Henrik S., Hansen, E. L., Hollensted, M., Madsbad, Sten, Hansen, Torben, Holst, Jens Juul, Holm, Jens-Christian & Torekov, Signe Sørensen, 2018, In: Cell Metabolism. 28, 1, p. 23-32.e3

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Patients with neuroglycopenia after gastric bypass surgery have exaggerated incretin and insulin secretory responses to a mixed meal

    Goldfine, A. B., Mun, E. C., Devine, E., Bernier, R., Baz-Hecht, M., Jones, D. B., Schneider, B. E., Holst, Jens Juul & Patti, M. E., 2007, In: Journal of Clinical Endocrinology and Metabolism. 92, 12, p. 4678-4685 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Patients with neuroglycopenia after gastric bypass surgery have exaggerated incretin and insulin secretory responses to a mixed meal

    Goldfine, A. B., Mun, E. C., Devine, E., Bernier, R., Baz-Hecht, M., Jones, D. B., Schneider, B. E., Holst, Jens Juul & Patti, M. E., Dec 2007, In: The Journal of clinical endocrinology and metabolism. 92, 12, p. 4678-85 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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