Jens Juul Holst

Jens Juul Holst

Professor


  1. Published

    Patients with psoriasis are insulin resistant

    Gyldenløve, M., Storgaard, H., Holst, Jens Juul, Vilsbøll, T., Knop, Filip Krag & Skov, Lone, Apr 2015, In: Journal of the American Academy of Dermatology. 72, 4, p. 599-605 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Peptide YY and glucagon-like peptide-1 contribute to decreased food intake after Roux-en-Y gastric bypass surgery

    Svane, M. S., Jørgensen, N. B., Bojsen-Møller, K. N., Dirksen, C., Nielsen, S., Kristiansen, V. B., Toräng, S., Albrechtsen, Nicolai Jacob Wewer, Rehfeld, Jens Frederik, Hartmann, Bolette, Madsbad, Sten & Holst, Jens Juul, 30 Aug 2016, In: International Journal of Obesity. 40, p. 1699–1706

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Peptide YY3-36 and glucagon-like peptide-1 in functional dyspepsia. Secretion and role in symptom generation

    Witte, A., Hilsted, Linda, Holst, Jens Juul & Schmidt, P. T., Apr 2016, In: Scandinavian Journal of Gastroenterology. 51, 4, p. 400-409 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Peptide production and secretion in GLUTag, NCI-H716 and STC-1 cells: a comparison to native L-cells.

    Kuhre, Rune Ehrenreich, Albrechtsen, Nicolai Jacob Wewer, Deacon, Carolyn F., Balk-Møller, E., Rehfeld, Jens Frederik, Relman, F., Gribble, F. M. & Holst, Jens Juul, 2016, In: Journal of Molecular Endocrinology. 56, p. 201-211

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Peptide-evoked release of amylase from isolated acini of the rat parotid gland

    Goll, R., Poulsen, J. H., Schmidt, P., Schjoldager, B., Poulsen, Steen Seier & Holst, Jens Juul, 26 May 1994, In: Regulatory Peptides. 51, 3, p. 237-54 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Peptidergic control of amylase secretion from the rat parotid gland

    Goll, R., Poulsen, J. H., Schmidt, P., Schjoldager, B., Poulsen, S. S. & Holst, Jens Juul, 1994, In: Regulatory Peptides. 51, p. 237-254

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Peptides in the regulation of glucagon secretion

    Andersen, Daniel Bjørklund & Holst, Jens Juul, 2022, In: Peptides. 148, 19 p., 170683.

    Research output: Contribution to journalReviewResearchpeer-review

  8. Published

    Peptone-mediated glucagon-like peptide-1 secretion depends on intestinal absorption and activation of basolaterally located Calcium-Sensing Receptors

    Modvig, Ida Marie, Kuhre, Rune Ehrenreich & Holst, Jens Juul, Apr 2019, In: Physiological Reports. 7, 8, 13 p., e14056.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Perinatal gut growth is not regulated by glucagon-like peptide 2

    Petersen, Y. M., Holst, Jens Juul, Hartmann, B. & Sangild, Per Torp, 2001, Journal of the Society for Gynecological Investigation. 8 ed. p. 172A 1 p.

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearch

  10. Published

    Peripheral administration of GLP-2 to humans has no effect on gastric emptying or satiety

    Schmidt, P. T., Näslund, E., Grybäck, P., Jacobsson, H., Hartmann, B., Holst, Jens Juul & Hellström, P. M., 2003, In: Regul. Pept.. 116, p. 21-25

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Peripheral administration of GLP-2 to humans has no effect on gastric emptying or satiety

    Schmidt, P. T., Näslund, E., Grybäck, P., Jacobsson, H., Hartmann, Bolette, Holst, Jens Juul & Hellström, P. M., 15 Nov 2003, In: Regulatory Peptides. 116, 1-3, p. 21-5 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Pharmacodynamics of vildagliptin in patients with type 2 diabetes during OGTT.

    He, Y., Wang, Y., Bullock, J. M., Deacon, Carolyn F., Holst, Jens Juul, Dunning, B. E., Ligueros-Saylan, M. & Foley, J. E., 2007, In: Journal of Clinical Pharmacology. 47, 5, p. 633-41 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Pharmacokinetic, insulinotropic and glucagonostatic properties of GLP-1 (7-36 amide) after subcutaneous injection in healthy volunteers. Dose-response-relationships

    Ritzel, R., Ørskov, Cathrine, Holst, Jens Juul & Nauck, M. A., 1995, In: Diabetologia. 38, p. 720-725

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Pharmacokinetics and pharmacodynamics of vildagliptin in patients with type 2 diabetes mellitus.

    He, Y., Serra, D., Wang, Y., Campestrini, J., Riviere, G., Deacon, Carolyn F., Holst, Jens Juul, Schwartz, S., Nielsen, J. C. & Ligueros-Saylan, M., 2007, In: Clinical Pharmacokinetics. 46, 7, p. 577-88 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Pharmacokinetics of exogenous GIP(1-42) in C57Bl/6 mice; Extremely rapid degradation but marked variation between available assays

    Boer, G. A., Hartmann, Bolette & Holst, Jens Juul, 2021, In: Peptides. 136, 7 p., 170457.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Pharmacological activation of TGR5 promotes intestinal growth via a GLP-2 dependent pathway in mice

    Dal, Jenna Elizabeth Hunt, Billeschou, Anna, Windeløv, Johanne Agerlin, Hartmann, Bolette, Ullmer, C., Holst, Jens Juul & Kissow, Hannelouise, 2020, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 318, 6, p. G980-G987

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Physiological and pharmacological mechanisms through which the DPP-4 inhibitor sitagliptin regulates glycemia in mice

    Waget, A., Cabou, C., Masseboeuf, M., Cattan, P., Armanet, M., Karaca, M., Castel, J., Garret, C., Payros, G., Maida, A., Sulpice, T., Holst, Jens Juul, Drucker, D. J., Magnan, C. & Burcelin, R., Aug 2011, In: Endocrinology. 152, 8, p. 3018-3029 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Physiological augmentation of amino acid-induced insulin secretion by GIP and GLP-I but not by CCK-8

    Fieseler, P., Bridenbaugh, S., Nustede, R., Martell, J., Nauck, M. A., Ørskov, Cathrine & Holst, Jens Juul, 1995, In: Am. J. Physiol.. Vol 268, p. E949-E955

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Physiology of the Incretin Hormones, GIP and GLP-1-Regulation of Release and Posttranslational Modifications

    Holst, Jens Juul, Albrechtsen, Nicolai Jacob Wewer, Rosenkilde, Mette & Deacon, Carolyn F., 2019, In: Comprehensive Physiology. 9, 4, p. 1339-1381

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Pigs produce only a single form of CGRP, part of which is processed to N- and C-terminal fragments

    Rasmussen, T. N., Bersani, M., Johnsen, A. H., Kofod, H. & Holst, Jens Juul, 1994, In: Peptides. 15, 1, p. 89-94 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Pituitary adenylate-cyclase-activating polypeptide stimulates insulin and glucagon secretion in humans.

    Filipson, K., Tornøe, K., Holst, Jens Juul & Ahrén, B., 1997, In: J. Clin. Endocrinol. Metab.. 82, p. 3093-3098

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Plasma FGF-19 Levels are Increased in Patients with Post-Bariatric Hypoglycemia

    Mulla, C. M., Goldfine, A. B., Dreyfuss, J. M., Houten, S., Pan, H., Pober, D. M., Albrechtsen, Nicolai Jacob Wewer, Svane, M. S., Schmidt, J. B., Holst, Jens Juul, Craig, C. M., McLaughlin, T. L. & Patti, M., 2019, In: Obesity Surgery. 29, 7, p. 2092-2099

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Plasma GDF15 levels are similar between subjects after bariatric surgery and matched controls and are unaffected by meals

    Martinussen, C., Svane, M. S., Bojsen-Møller, K. N., Jensen, Christian Zinck, Kristiansen, V. B., Bookout, A. L., Jorgensen, S. B., Holst, Jens Juul, Albrechtsen, Nicolai Jacob Wewer, Madsbad, Sten & Kuhre, Rune Ehrenreich, 2021, In: American Journal of Physiology: Endocrinology and Metabolism. p. E443-E452 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Plasma GLP-2 levels and intestinal markers in the juvenile pig during intestinal adaptation: effects of different diet regimens

    Paris, M. C., Fuller, P. J., Carstensen, Bendix, Nagy, E., Taylor, R. G., Sourial, M., Holst, Jens Juul, Hartmann, Bolette & Binesm, J. E., Oct 2004, In: Digestive Diseases and Sciences. 49, 10, p. 1688-95 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Plasma GLP-2 levels and intestinal markers in the juvenile pig during intestinal adaptation: effects of different diet regimens

    Paris, M. C. J., Fuller, P. J., Taylor, R. G., Nagy, E., Sourial, M., Catto-Smith, T., Hartmann, B., Holst, Jens Juul & Bines, J. E., 2004, In: Dig. Dis. Sci.. 49, p. 1688-1695

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Plasma Proteome Profiling Reveals Dynamics of Inflammatory and Lipid Homeostasis Markers after Roux-En-Y Gastric Bypass Surgery

    Albrechtsen, Nicolai Jacob Wewer, Geyer, P. E., Doll, S., Treit, P. V., Bojsen-Møller, K. N., Martinussen, C., Jørgensen, N. B., Torekov, Signe Sørensen, Meier, F., Niu, Lili, Santos, A., Keilhauer, E. C., Holst, Jens Juul, Madsbad, Sten & Mann, Matthias, 2018, In: Cell Systems. 7, 6, p. 601-612

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Plasma dipeptidyl peptidase-IV activity in patients with type-2 diabetes mellitus correlates positively with HbAlc levels, but is not acutely affected by food intake

    Ryskjaer, J., Deacon, Carolyn F., Carr, R. D., Krarup, T., Madsbad, Sten, Holst, Jens Juul, Vilsbøll, Tina, Ryskjaer, J., Deacon, C. F., Carr, R. D., Krarup, T., Madsbad, Sten, Holst, J. J. & Vilsbøll, T., 1 Sep 2006, In: European Journal of Endocrinology. 155, 3, p. 485-93 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Plasma glucagon and glucose recovery after hypoglycemia: The effect of total autonomic blockade

    Hilsted, J., Frandsen, H., Holst, Jens Juul, Christensen, J. & Nielsen, S. L., 1991, In: Acta Endocrinol.. 125, p. 466-469

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Plasma glucagon-like peptide 1 and peptide YY levels are not altered in symptomatic fructose-sorbitol malabsorption.

    Valeur, J., Øines, E., Morken, M. H., Holst, Jens Juul & Berstad, A., 2008, In: Scandinavian Journal of Gastroenterology. 43, 10, p. 1212-8 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Plasma levels of glucagon but not GLP-1 are elevated in response to inflammation in humans

    Modrzynska, J., Klein, C. F., Iversen, Kasper, Bundgård, Henning, Hartmann, Bolette, Mose, M., Rittig, N., Møller, N., Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2021, In: Endocrine Connections. 10, 2, p. 205-213 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Plasma levels of glucagon like peptide-1 associate with diastolic function in elderly men

    Nathanson, D., Zethelius, B., Berne, C., Lind, L., Andrén, B., Ingelsson, E., Holst, Jens Juul & Nyström, T., Mar 2011, In: Diabetic Medicine. 28, 3, p. 301-305 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Plasma proteome profiling discovers novel proteins associated with non-alcoholic fatty liver disease

    Niu, Lili, Geyer, P. E., Albrechtsen, Nicolai Jacob Wewer, Gluud, Lise Lotte, Santos, A., Doll, S., Treit, P. V., Holst, Jens Juul, Knop, Filip Krag, Vilsbøll, Tina, Junker, A., Sachs, S., Stemmer, K., Müller, T. D., Tschöp, M. H., Hofmann, S. M. & Mann, Matthias, 2019, In: Molecular Systems Biology. 15, 16 p., e8793.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Plasma proteome profiling discovers potential biomarkers of non-alcoholic fatty liver disease

    Niu, Lili, Gupta, R., Geyer, P. E., Albrechtsen, Nicolai Jacob Wewer, Gluud, Lise Lotte, Santos, A., Doll, S., Holst, Jens Juul, Knop, Filip Krag, Vilsbøll, Tina, Junker, A., Sachs, S., Stemmer, K., Mueller, T. D., Tschoep, M. H., Hofmann, S. M. & Mann, Matthias, Aug 2019, In: Molecular & Cellular Proteomics. 18, 8, p. S71 1 p.

    Research output: Contribution to journalConference abstract in journalResearch

  34. Published

    Porcine glucagon-like peptide-2: structure, signaling, metabolism and effects

    Pedersen, N. B., Hjøllund, K. R., Johnsen, A. H., Ørskov, Cathrine, Rosenkilde, Mette, Hartmann, B. & Holst, Jens Juul, 2007, In: Regulatory Peptides. 146, 1-3, p. 310-320 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Positive effects on plasma glucose & appetite by industrial modification of starch

    Raben, A., Andersen, K., Karberg, M. A., Holst, Jens Juul & Astrup, A., 1996. 1 p.

    Research output: Contribution to conferencePosterResearch

  36. Published

    Possible role of adiponectin and insulin sensitivity in mediating the favorable effects of lower body fat mass on blood lipids

    Buemann, B., Astrup, A., Pedersen, O., Black, E., Holst, C., Toubro, S., Echwald, S., Holst, Jens Juul, Rasmussen, C. & Sørensen, Thorkild I.A., 2006, In: Journal of Clinical Endocrinology and Metabolism. 91, 5, p. 1698-1704 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Post-prandial secretion of glucagon-like peptide-2 (GLP-2) after carbohydrate-, fat- or protein enriched meals in healthy subjects

    Prahm, A. P., Hvistendahl, M. K., Brandt, Christopher Filtenborg, Blanche, Paul Frédéric, Hartmann, Bolette, Holst, Jens Juul & Jeppesen, Palle Bekker, 2023, In: Peptides. 169, 8 p., 171091.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Post-surgical effects of Roux-En-Y gastric bypass on glucose homeostasis, intestinal morphology and L-cells in obese Göttingen minipigs

    Barkholt, P., Vegge, A., Clausen, T. R., Birck, M. M., Fels, J. J., Støckel, M., Gögenur, Ismail, Eriksen, Thomas, Holst, Jens Juul, Hansen, Axel Kornerup, Thymann, Thomas, Jelsing, J., Sangild, Per Torp & Raun, K., 2015, In: Journal of Obesity and Bariatrics. 1, 1, 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Postprandial Dyslipidemia, Hyperinsulinemia, and Impaired Gut Peptides/Bile Acids in Adolescents with Obesity

    Higgins, V., Asgari, S., Hamilton, J. K., Wolska, A., Remaley, A. T., Hartmann, Bolette, Holst, Jens Juul & Adeli, K., 2020, In: Journal of Clinical Endocrinology & Metabolism. 105, 4, p. 1228-1241

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Postprandial GLP-1, norepinephrine, and reactive hypoglycemia in dumping syndrome

    Gebhard, B., Holst, Jens Juul & Biegelmayer, C., 2001, In: Digest Dis Sci. 46, p. 1915-1923

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Postprandial Nutrient Handling and Gastrointestinal Hormone Secretion After Roux-en-Y Gastric Bypass vs Sleeve Gastrectomy

    Svane, M. S., Bojsen-Moller, K. N., Martinussen, C., Dirksen, C., Madsen, J. L., Reitelseder, S., Holm, L., Rehfeld, Jens Frederik, Kristiansen, V. B., van Hall, Gerrit, Holst, Jens Juul & Madsbad, Sten, 2019, In: Gastroenterology. 156, 6, p. 1627-1641

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Postprandial diabetic glucose tolerance is normalized by gastric bypass feeding as opposed to gastric feeding and is associated with exaggerated GLP-1 secretion: a case report

    Dirksen, C., Hansen, D. L., Madsbad, Sten, Hvolris, L. E., Naver, L. S., Holst, Jens Juul & Worm, Dorte, 2010, In: Diabetes Care. 33, 2, p. 375-377

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Postprandial effects of individual and combined GIP and GLP-1 receptor antagonism in healthy subjects

    Gasbjerg, Lærke Smidt, Helsted, M. M., wbf943, wbf943, Lanng, A. R., Stensen, S., Jakobsen, M. H., Hartmann, Bolette, Christensen, Mikkel Bring, Holst, Jens Juul, Vilsbøll, Tina, Rosenkilde, M. M. & Knop, Filip Krag, 2018, In: Diabetologia. 61, S1, p. S246-S246 503.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  44. Published

    Postprandial effects of test meals including concentrated arabinoxylan and whole grain rye in subjects with the metabolic syndrome: a randomised study

    Hartvigsen, M. L., Lærke, H. N., Overgaard, A., Holst, Jens Juul, Bach Knudsen, K. E. & Hermansen, K., May 2014, In: European Journal of Clinical Nutrition. 68, 5, p. 567-74 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Postprandial gallbladder emptying in patients with type 2 diabetes: potential implications for bile-induced secretion of glucagon-like peptide 1

    Sonne, David Peick, Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, Oct 2014, In: European Journal of Endocrinology. 171, 4, p. 407-419 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Postprandial glucagon-like peptide-1 (GLP-1) release in states of normal and disturbed luminal nutrient digestion.

    Layer, P., v d Ohe, M. & Holst, Jens Juul, 1995, Gastrointestinal Tract and Endocrine System. Dordrecht/Boston/London: Kluwer Academic Publishers, p. 547-550

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  47. Published

    Postprandial glucose, insulin and incretin responses to grain products in healthy subjects

    Juntunen, K. S., Lioukkonen, H. K., Poutanen, S. K., Niskanen, K. L., Holst, Jens Juul & Mykkänen, M. H., 2002, In: Am. J. Clin. Nutr.. 75, p. 254-262

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Postprandial gut hormone responses and glucose metabolism in cholecystectomized patients

    Sonne, D. P., Hare, K. J., Martens, P., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, 15 Feb 2013, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 304, 4, p. G413-9 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Postprandial hypoglycaemia after Roux-en-Y gastric bypass and the effects of acarbose, sitagliptin, verapamil, liraglutide and pasireotide

    Ohrstrom, C. C., Worm, Dorte, Hojager, A., Andersen, D., Holst, Jens Juul, Kielgast, U. L. & Hansen, D. L., 2019, In: Diabetes, Obesity and Metabolism. 21, 9, p. 2142-2151

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Postprandial incretin and islet hormone responses and dipeptidyl-peptidase 4 enzymatic activity in patients with maturity onset diabetes of the young

    Østoft, S. H., Bagger, J. I., Hansen, Torben, Hartmann, Bolette, Pedersen, Oluf Borbye, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 1 Aug 2015, In: European Journal of Endocrinology. 173, 2, p. 205-215 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 4207