Jens Juul Holst

Jens Juul Holst

Professor

ORCID: 0000-0001-6853-3805

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  1. Published

    Postprandial insulin secretion after gastric bypass surgery: the role of glucagon-like peptide 1

    Holst, Jens Juul, Sep 2011, In: Diabetes. 60, 9, p. 2203-2205 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Postprandial levels of GLP-1, GIP and glucagon after 2 years of weight loss with a Paleolithic diet: a randomised controlled trial in healthy obese women

    Otten, J., Ryberg, M., Mellberg, C., Andersson, T., Chorell, E., Lindahl, B., Larsson, C., Holst, Jens Juul & Olsson, T., 2019, In: European Journal of Endocrinology. 180, 6, p. 417-427

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Postprandial lipid oxidation reduced and carbohydrate oxidation increased in postobese subjects

    Raben, A., Andersen, H. B., Christensen, N. J., Madsen, J., Holst, Jens Juul & Astrup, A., 1994, Obesity in Europe. John Libbey, p. 135-137

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  4. Published

    Postprandial release of glucagon-like peptide-1, pancreatic glucagon, and insulin after esophageal resection

    Miholic, J., Ørskov, C., Holst, Jens Juul, Kotzerke, J. & Pichlmayr, R., 1993, In: Digestion. 54, p. 73-78

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Postprandial renal hemodynamic effects of DPP-4 inhibitor linagliptin versus sulfonylurea glimepiride in adults with type 2 diabetes (RENALIS): a pre-defined sub-study of a randomized, double-blind trial

    Muskiet, M. H. A., Tonneijck, L., Smits, M. M., Kramer, M. H. H., Ouwens, D. M., Hartmann, Bolette, Holst, Jens Juul, Danser, A. H. J., Joles, J. A. & van Raalte, D. H., 2022, In: Diabetes, Obesity and Metabolism. 24, 1, p. 115-124

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Postprandial responses of incretin and pancreatic hormones in non-diabetic patients with end-stage renal disease

    Idorn, T., Knop, Filip Krag, Jørgensen, M., Holst, Jens Juul, Hornum, Mads & Feldt-Rasmussen, Bo, Jan 2014, In: Nephrology, Dialysis, Transplantation. 29, 1, p. 119-27 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Postprandial secretion of follistatin after gastric bypass surgery and sleeve gastrectomy

    Richter, Michael Martin, Svane, M. S., Kristiansen, V. B., Holst, Jens Juul, Madsbad, Sten & Bojsen-Møller, K. N., 2023, In: Peptides. 163, 8 p., 170978.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Posttranslational processing of proglucagon and postsecretory fate of proglucagon products.

    Holst, Jens Juul, Ørskov, C., Hartmann, B. & Deacon, Carolyn F., 1997, The Insulinotropic Gut Hormone Glucagon-like Peptide-1.. Basel: Karger, p. 24-48

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  9. Published

    Potent inhibitory effects of transplantable rat glucagonomas and insulinomas on the respective endogenous islet cells are associated with pancreatic apoptosis.

    Blume, N., Skouv, J., Larsson, L., Holst, Jens Juul & Madsen, O. D., 1995, In: J. Clin. Invest.. 96, p. 2227-2235

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Potential new approaches to modifying intestinal GLP-1 secretion in patients with type 2 diabetes mellitus: focus on bile acid sequestrants

    Holst, Jens Juul & McGill, M. A., 2012, In: Clinical Drug Investigation. 32, 1, p. 1-14 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Potential targets for glucagon-like peptide 2 (GLP-2) in the rat: distribution and binding of i.v. injected (125)I-GLP-2

    Thulesen, J., Hartmann, Bolette, Ørskov, Cathrine, Jeppesen, Palle Bekker, Holst, Jens Juul & Poulsen, Steen Seier, Oct 2000, In: Peptides. 21, 10, p. 1511-7 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Potential targets for glucagon-like peptide 2 (GLP-2) in the rat: distribution and binding of i.v. injected (125)I-GLP-2

    Thulesen, J., Hartmann, B., Ørskov, Cathrine, Jeppesen, P. B., Holst, Jens Juul & Poulsen, Steen Seier, 2000, In: Peptides. 10, p. 1511-1517

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Prandial subcutaneous injections of glucagon-like peptide-1 cause weight loss in obese human subjects

    Näslund, E., King, N., Mansten, S., Adner, N., Holst, Jens Juul, Gutniak, M. & Hellström, P. M., Mar 2004, In: The British Journal of Nutrition. 91, 3, p. 439-46 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Prandial subcutaneous injections of glucagons-like peptide- 1 cause weight loss in obese human subjects

    Näslund, E., King, N., Mansten, S., Adner, N., Holst, Jens Juul, Gutniak, M. & Hellström, P., 2004, In: Br.J.Nutr.. 91, p. 439-446

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Pre-Meal Effect of Whey Proteins on Metabolic Parameters in Subjects with and without Type 2 Diabetes: A Randomized, Crossover Trial

    Bjørnshave, A., Hermansen, K. & Holst, Jens Juul, 2018, In: Nutrients. 10, 2, p. 1-13 122.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Pre-meal and postprandial lipaemia in subjects with the metabolic syndrome: effects of timing and protein quality (randomised crossover trial)

    Bjørnshave, A., Johansen, T. N., Amer, B., Dalsgaard, T. K., Holst, Jens Juul & Hermansen, K., 2019, In: British Journal of Nutrition. 121, 3, p. 312-321

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Preanalytical impact on the accuracy of measurements of glucagon, GLP-1 and GIP in clinical trials

    Rasmussen, C., Richter, Michael Martin, Jensen, N. J., Heinz, N., Hartmann, Bolette, Holst, Jens Juul, Kjeldsen, Sasha Alexandra Sampson & Albrechtsen, Nicolai Jacob Wewer, 2023, In: Scandinavian Journal of Clinical and Laboratory Investigation. 83, 8, p. 591-598

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Prediction of glycemic index in mixed meals

    Møller, B. K., Flint, A., Pedersen, D., Raben, A. B., Tetens, I., Holst, Jens Juul & Astrup, A., 2003. 1 p.

    Research output: Contribution to conference › Paper › Research

  19. Published

    Predictors of incretin concentrations in subjects with normal, impaired, and diabetic glucose tolerance

    Vollmer, K., Holst, Jens Juul, Baher, B., Ellrichmann, M., Nauck, M. A., Schmidt, W. E. & Meier, J. J., 2008, In: Diabetes. 57, 3, p. 678-687 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Predictors of weight loss after bariatric surgery - a cross-disciplinary approach combining physiological, social, and psychological measures

    Nielsen, M. S., Christensen, Bodil Just, Schmidt, J. B., Tækker, L., Holm, Lotte, Lunn, Susanne, Ritz, C., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Schnurr, T. M., Hansen, Torben, le Roux, C. W., Lund, Thomas Bøker, Floyd, A. K. & Sjödin, Anders Mikael, 2020, In: International Journal of Obesity. 44, 11, p. 2291-2302 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Preliminary report: genetic variation within the GPBAR1 gene is not associated with metabolic traits in white subjects at an increased risk for type 2 diabetes mellitus

    Müssig, K., Staiger, H., Machicao, F., Machann, J., Schick, F., Schäfer, S. A., Claussen, C. D., Holst, Jens Juul, Gallwitz, B., Stefan, N., Fritsche, A. & Häring, H., 2009, In: Metabolism - Clinical and Experimental. 58, 12, p. 1809-11 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Preoperative β-cell function in patients with type 2 diabetes is important for the outcome of Roux-en-Y gastric bypass surgery

    Lund, M. T., Hansen, M., Skaaby, Stinna, Dalby, S., Støckel, M., Floyd, A. K., Bech, K., Helge, Jørn Wulff, Holst, Jens Juul & Dela, Flemming, 13 Apr 2015, In: The Journal of Physiology. 593, 14, p. 3123-33 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Presence of somatostatin containing neuronal-like cells in the rat pineal gland.

    Møller, M., Holst, Jens Juul, Mikkelsen, J. D. & Webb, S., 1995, In: Neuroendocrinol. Letters. 17, p. 71-80

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Preservation of active Effects of topical ropivacaine om eicosanoids and neurotransmitters in the rectum of patients with distal ulcerative colitis

    Hillingsøe, J. G., Kjeldsen, J., Schmidt, P. T., Rasmussen, T. N., Arlander, E., Fischer-Hansen, B., Holst, Jens Juul, Lauritsen, K., Bukhave, K. & Rask-Madsen, J., 2002, In: Scandinavian Journal of Gastroenterology. 37, p. 325-329

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Preservation of active incretin hormones by inhibition of dipeptidyl peptidase IV suppresses meal-induced incretin secretion in dogs

    Deacon, Carolyn F., Wamberg, S., Bie, P., Hughes, T. E. & Holst, Jens Juul, Feb 2002, In: Journal of Endocrinology. 172, 2, p. 355-62 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Preserved GLP-1 and exaggerated GIP secretion in type 2 diabetes and relationships with triglycerides and ALT

    Alssema, M., Rijkelijkhuizen, J. M., Holst, Jens Juul, Teerlink, T., Scheffer, P. G., Eekhoff, E. M. W., Gastaldelli, A., Mari, A., Hart, L. M., Nijpels, G. & Dekker, J. M., Oct 2013, In: European Journal of Endocrinology. 169, 4, p. 421-30 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Preserved GLP-1 effects in a diabetic patient with Cushing's disease

    Ritzel, R. A., Kleine, N., Holst, Jens Juul, Willms, B., Schmiegel, W. & Nauck, M. A., Feb 2007, In: Experimental and Clinical Endocrinology and Diabetes. 115, 2, p. 146-50 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Preserved GLP-1 effects in a diabetic patient with Cushing's disease

    Ritzel, R. A., Kleine, N., Holst, Jens Juul, Willms, B., Schmiegel, W. & Nauck, M. A., 2007, In: Experimental and Clinical Endocrinology and Diabetes. 115, 2, p. 146-150 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Preserved glucagon-like peptide-1 responses to oral glucose, but reduced incretin effect, insulin secretion and sensitivity in young Asians with type 2 diabetes mellitus

    Yeow, T. P., Pacini, G., Tura, A., Hor, C. P., Lim, S. L., Tan, F. H. S., Tong, C. V., Hong, J. Y. H., Md Zain, F., Holst, Jens Juul & Wan Mohamud, W. N., 2017, In: BMJ open diabetes research & care. 5, 1, 9 p., e000352.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Preserved glucose response to low-dose glucagon after exercise in insulin pump-treated individuals with type 1 diabetes: a randomised crossover study

    Steineck, I. I. K., Ranjan, A., Schmidt, S., Clausen, T. R., Holst, Jens Juul & Norgaard, K., 2018, In: Diabetologia. 61, S1, p. S75-S76 2 p., 146.

    Research output: Contribution to journal › Conference abstract in journal › Research

  31. Published

    Preserved glucose response to low-dose glucagon after exercise in insulin-pump-treated individuals with type 1 diabetes: a randomised crossover study

    Steineck, I. I. K., Ranjan, A., Schmidt, S., Clausen, T. R., Holst, Jens Juul & Nørgaard, Kirsten, 2019, In: Diabetologia. 62, 4, p. 582-592

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Preserved incretin activity of glucagon-like peptide 1 (7-36 amide) but not of synthetic human gastric inhibitory polypeptide in patients with type-2 diabetes mellitus

    Nauck, M. A., Heimesaat, M. M., Ørskov, C., Holst, Jens Juul, Ebert, R. & Creutzfeldt, W., 1993, In: Journal of Clinical Investigation. 91, p. 301-307

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Preserved inhibitory potency of GLP-1 on glucagon secretion in type 2 diabetes mellitus

    Hare, K. J., Knop, Filip Krag, Asmar, M., Madsbad, Sten, Deacon, Carolyn F., Holst, Jens Juul & Vilsbøll, Tina, 2009, In: Journal of Clinical Endocrinology and Metabolism. 94, 12, p. 4679-87 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Preserved postprandial GLP-1 and GIP responses in patients with maturity onset diabetes of the young

    Bagger, J. I., Ostoft, S. H., Hansen, T., Pedersen, O., Holst, Jens Juul, Knop, Filip Krag & Vilsboll, T., 2013, In: Diabetologia. 56, p. S152-S152

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Preserved postprandial suppression of bone turnover markers, despite increased fasting levels, in postmenopausal women

    Abildgaard, J., Ploug, Thorkil, Pedersen, Anette Tønnes, Eiken, P., Pedersen, Bente Klarlund, Holst, Jens Juul, Hartmann, Bolette & Lindegaard, Birgitte, 2021, In: Bone. 143, 8 p., 115612.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Primary weight loss failure after Roux-en-Y gastric bypass is characterized by impaired gut-hormone mediated regulation of food intake

    Bojsen-Møller, Kirstine Nyvold, Svane, M. S., Martinussen, C., Dirksen, Carsten Moro, Jørgensen, Nils Bruun, Jensen, Jens-Erik Beck, Jensen, Christian Zinck, Torekov, Signe Sørensen, Kristiansen, V. B., Rehfeld, Jens Frederik, Bork-Jensen, J., Grarup, N., Hansen, Torben, Hartmann, Bolette, Holst, Jens Juul & Madsbad, Sten, 2023, In: International Journal of Obesity. 47, 11, p. 1143-1151 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Production and secretion of amidated and glycine-extended glucagon-like peptide-1 (GLP) in man

    Ørskov, C., Rabenhøj, L., Kofod, H., Wettergren, A. & Holst, Jens Juul, 1994, In: Diabetes. 43, p. 535-39

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Proglucagon cleavage profile in canine L-cells expressing endogenous PC-1/3 and PC-2

    Damholt, A. B., Buchan, A. M. J., Holst, Jens Juul & Kofod, H., 1999, In: Endokrinologiya. 140, p. 4800-4808

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Proglucagon peptide secretion profiles in type 2 diabetes before and after bariatric surgery: 1-year prospective study

    Alexiadou, K., Cuenco, J., Howard, J., Albrechtsen, Nicolai Jacob Wewer, Ilesanmi, I., Kamocka, A., Tharakan, G., Behary, P., Bech, P. R., Ahmed, A. R., Purkayastha, S., Wheller, R., Fleuret, M., Holst, Jens Juul, Bloom, S. R., Khoo, B. & Tan, T. M. M., 2020, In: B M J Open Diabetes Research & Care. 8, 1, 10 p., e001076.

    Research output: Contribution to journal › Review › Research › peer-review

  40. Published

    Proglucagon processing in porcine and human pancreas

    Holst, Jens Juul, Bersani, M., Johnsen, A. H., Kofod, H., Hartmann, Bolette & Ørskov, Cathrine, 1994, In: Journal of Biological Chemistry. 269, 29, p. 18827-33 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Proglucagon processing profile in canine L cells expressing endogenous prohormone convertase 1/3 and prohormone convertase 2

    Damholt, A. B., Buchan, A. M., Holst, Jens Juul & Kofod, H., Oct 1999, In: Endocrinology. 140, 10, p. 4800-8 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Proglucagon products in plasma of noninsulin-dependent diabetics and nondiabetic controls in the fasting state and after oral glucose and intravenous arginine

    Ørskov, Cathrine, Jeppesen, J., Madsbad, Sten & Holst, Jens Juul, Feb 1991, In: The Journal of Clinical Investigation. 87, 2, p. 415-23 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Proglucagon products in plasma of noninsulin-dependent diabetics and nondiabetic controls in the fasting-state and after oral glucose and intravenous arginine

    Ørskov, C., Jeppesen, J., Madsbad, J. & Holst, Jens Juul, 1991, In: J. Clin. Invest.. 87, p. 415-423

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Proglucagon products in plasma of uraemic patients and normals in the fasting state

    Ørskov, C., Andreasen, J. & Holst, Jens Juul, 1992, In: J. Clin. Endocrinol. Metab.. 74, p. 379-384

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Progression from normal glucose tolerance to impaired fasting glycaemia and impaired glucose tolerance: differential roles of insulin resistance and beta cell dysfunction

    Faerch, K., Vaag, Allan, Holst, Jens Juul, Pedersen, O., Glumer, C. & Borch-Johnsen, K., 2008, In: Diabetologia. 51, Suppl. 1, p. S85-S86

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Prohormone convertase 1/3 is essential for processing of the glucose-dependent insulinotropic polypeptide precursor

    Ugleholdt, Randi Kjærsgaard, Poulsen, M. H., Holst, Peter Johannes, Irminger, J., Orskov, C., Pedersen, Jens, Rosenkilde, Mette, Zhu, X., Steiner, D. F. & Holst, Jens Juul, 2006, In: Journal of Biological Chemistry. 281, 16, p. 11050-7 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Prolonged and enhanced secretion of glucagon-like peptide 1 (7-36 amide) after oral sucrose due to alpha-glucosidase inhibition (acarbose) in Type 2 diabetic patients

    Seifarth, C., Bergmann, J., Holst, Jens Juul, Ritzel, R., Schmiegel, W. & Nauck, M. A., 1998, In: Diabet. Med.. 15, p. 485-491

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Prolonged lipopolysaccharide-induced illness elevates glucagon-like peptide-1 and suppresses peptide YY: A human-randomized cross-over trial

    Brodersen, K., Mose, M., Ramer Mikkelsen, U., Jørgensen, J. O. L., Festersen Nielsen, M., Møller, N., Wegeberg, A., Brock, C., Hartmann, Bolette, Holst, Jens Juul & Rittig, N., 2022, In: Physiological Reports. 10, 18, 12 p., e15462.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Prolonged successful therapy for hyperinsulinaemic hypoglycaemia after gastric bypass: the pathophysiological role of GLP1 and its response to a somatostatin analogue

    Myint, K. S., Greenfield, J. R., Farooqi, I. S., Henning, E., Holst, Jens Juul & Finer, N., 2012, In: European Journal of Endocrinology. 166, 5, p. 951-5 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Propionate absorbed from the colon acts as gluconeogenic substrate in a strict carnivore, the domestic cat (Felis catus)

    Verbrugghe, A., Hesta, M., Daminet, S., Polis, I., Holst, Jens Juul, Buyse, J., Wuyts, B. & Janssens, G. P. J., Dec 2012, In: Journal of Animal Physiology and Animal Nutrition (Online). 96, 6, p. 1054-64 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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