Jens Juul Holst

Jens Juul Holst

Professor

ORCID: 0000-0001-6853-3805

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  1. Published

    Proteomics reveals the effects of sustained weight loss on the human plasma proteome

    Geyer, P. E., Albrechtsen, Nicolai Jacob Wewer, Tyanova, S., Grassl, N., Iepsen, E. P. W., Lundgren, J., Madsbad, Sten, Holst, Jens Juul, Torekov, Signe Sørensen & Mann, Matthias, 22 Dec 2016, In: Molecular Systems Biology. 12, 16 p., 901.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Protocol for a randomised controlled trial of the combined effects of the GLP-1 receptor agonist liraglutide and exercise on maintenance of weight loss and health after a very low-calorie diet

    Jensen, Simon Birk Kjær, Lundgren, J. R., Janus, C., Juhl, C. R., Olsen, L. M., Rosenkilde, M., Holst, Jens Juul, Stallknecht, Bente Merete, Madsbad, Sten & Torekov, Signe Sørensen, 2019, In: BMJ Open. 9, 11, 10 p., e031431.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Protocol for a single-centre, parallel-group, randomised, controlled, superiority trial on the effects of time-restricted eating on body weight, behaviour and metabolism in individuals at high risk of type 2 diabetes: the REStricted Eating Time (RESET) study

    Quist, Jonas Salling, Jensen, M. M., Clemmensen, K. K. B., Pedersen, H., Bjerre, N., Størling, Joachim, Blond, M. B., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Torekov, Signe Sørensen, Vistisen, D., Jørgensen, M. E., Panda, S., Brock, C., Finlayson, G. & Faerch, K., 2020, In: BMJ Open. 10, 8, 11 p., 037166.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Protocol to assess arteriovenous differences across the liver and hindlimb muscles in mice following treadmill exercise

    Ashcroft, Stephen Paul, Jepsen, Sara Lind, Ehrlich, Amy M, Treebak, Jonas Thue, Holst, Jens Juul & Zierath, Juleen R, 2023, In: STAR Protocols. 4, 1, 11 p., 101985.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Pterostilbene Fails to Rescue Insulin Secretion and Sensitivity in Multiple Murine Models of Diabetes

    Damgaard, Mads Vargas, Jepsen, Sara Lind, Ashcroft, Stephen Paul, Holst, Jens Juul & Treebak, Jonas Thue, 2022, In: Nutrients. 14, 18, 11 p., 3741.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Quantification of the contribution of GLP-1 to mediating insulinotropic effects of DPP-4 inhibition with vildagliptin in healthy subjects and type 2-diabetic patients using exendin [9-39] as a GLP-1 receptor antagonist.

    Nauck, M. A., Kind, J., Köthe, L. D., Holst, Jens Juul, Deacon, Carolyn F., Broschag, M., He, Y., Kjems, L. & Foley, J., 2016, In: Diabetes. 65, 8, p. 2440-2447 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    RETRACTION: Glucose-Dependent Insulinotropic Polypeptide Increases Blood Flow in Adipose Tissue of Humans by Recruiting Capillaries (Retraction of Vol 104, Pg 16, 2019)

    Asmar, M., Asmar, A., Simonsen, L., Holst, Jens Juul & Bulow, J., 2019, In: Journal of Clinical Endocrinology & Metabolism. 104, 1, p. W1-W9

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Radio-immunoassays for glucagon-like peptides 1 and 2 (GLP-1 and GLP-2)

    Ørskov, Cathrine & Holst, Jens Juul, Apr 1987, In: Scandinavian Journal of Clinical and Laboratory Investigation. Supplement. 47, 2, p. 165-74 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Randomised controlled trial of colostrum to improve intestinal function in patients with short bowel syndrome

    Lund, P., Sangild, Per Torp, Aunsholt, L., Hartmann, Bolette, Holst, Jens Juul, Mortensen, J., Mortensen, P. B. & Jeppesen, P. B., 2012, In: European Journal of Clinical Nutrition. 66, 9, p. 1059-1065 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Rapid gut growth but persistent delay in digestive function in the postnatal period of preterm pigs

    Hansen, C. F., Thymann, Thomas, Andersen, A. D., Holst, Jens Juul, Hartmann, Bolette, Hilsted, Linda, Langhorn, L., Jelsing, J. & Sangild, Per Torp, 28 Jan 2016, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 310, 8, p. G550-560 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Rapid tachyphylaxis of the glucagon-like peptide 1-induced deceleration of gastric emptying in humans

    Nauck, M. A., Kemmeries, G., Holst, Jens Juul & Meier, J. J., 2011, In: Diabetes. 60, 5, p. 1561-5 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Rare Heterozygous Loss-of-Function Variants in the Human GLP-1 Receptor Are Not Associated With Cardiometabolic Phenotypes

    Melchiorsen, Josefine Ulrikke, Sørensen, Kimmie Vestergaard, Bork-Jensen, J., Kizilkaya, Hüsün Sheyma, Gasbjerg, Lærke Smidt, Hauser, Alexander Sebastian, Rungby, Jørgen, Sørensen, H. T., Vaag, Allan, Nielsen, J. S., Pedersen, Oluf Borbye, Linneberg, Allan René, Hartmann, Bolette, Gjesing, A. P., Holst, Jens Juul, Hansen, Torben, Rosenkilde, Mette & Grarup, N., 2023, In: Journal of Clinical Endocrinology and Metabolism. 108, 11, p. 2821–2833 38 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Rat parietal cell receptors for GLP-1 (7-36) amide: Northern blot, cross-linking, and radioligand binding

    Schmidtler, J., Dehne, K., Allescher, H. D., Schusdziarra, V., Classen, M., Holst, Jens Juul, Polack, A. & Schepp, W., 1994, In: Am. J. Physiol.. 267, p. G423-G432

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Recent advances of GIP and future horizons

    Holst, Jens Juul & Rosenkilde, Mette, 2020, In: Peptides. 125, 6 p., 170230.

    Research output: Contribution to journal › Review › Research › peer-review

  15. Published

    Receptor-mediated activation of gastric vagal afferents by glucagon-like peptide-1 in the rat

    Bucinskaite, V., Tolessa, T., Pedersen, J., Rydqvist, B., Zerihun, L., Holst, Jens Juul & Hellström, P. M., 2009, In: Neurogastroenterology and Motility. 21, 9, p. 978-e78

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Reduced GLP-1 Secretion at 30 Minutes After a 75g Oral Glucose Load is Observed in Gestational Diabetes Mellitus: A Prospective Cohort Study

    Sukumar, N., Bagias, C., Goljan, I., Weldeselassie, Y., Gharanei, S., Tan, B. K., Holst, Jens Juul & Saravanan, P., 1 Dec 2018, In: Diabetes. 67, 12, p. 2650-2656

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Reduced adipose tissue lymphatic drainage of macromolecules in obese subjects: a possible link between obesity and local tissue inflammation?

    Arngrim, N., Simonsen, L., Holst, Jens Juul & Bülow, J., 2012, In: International Journal of Obesity. 37, p. 748-50

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Reduced carbohydrate and increased protein and fat during weight loss improve the atherogenic lipid profile in type 2 diabetes

    Thomsen, M. N., Skytte, M. J., Samkani, A., Astrup, A., Frystyk, J., Chabanova, E., Hartmann, Bolette, Holst, Jens Juul, Larsen, T. M., Madsbad, Sten, Magkos, Faidon, Thomsen, Henrik S., Walzem, R. L., Krarup, T. & Haugaard, Steen Bendix, 2021, In: Diabetologia. 64, SUPPL 1, p. 60-60 109.

    Research output: Contribution to journal › Conference abstract in journal › Research

  19. Published

    Reduced carbohydrate and increased protein and fat in the diet augment the positive effect of weight loss on glucose control in type 2 diabetes patients

    Thomsen, M. N., Skytte, M. J., Samkani, A., Carl, M. H., Weber, P., Astrup, A., Larsen, T. M., Frystyk, J., Holst, Jens Juul, Hartmann, Bolette, Thomsen, Henrik S., Chabanova, E., Madsbad, Sten, Haugaard, Steen Bendix & Krarup, T., 2020, In: Diabetologia. 63, Suppl. 1, p. S295-S296 614.

    Research output: Contribution to journal › Conference abstract in journal › Research

  20. Published

    Reduced glucose tolerance and insulin resistance induced by steroid treatment, relative physical inactivity, and high-calorie diet impairs the incretin effect in healthy subjects

    Hansen, K. B., Vilsbøll, Tina, Bagger, J. I., Holst, Jens Juul & Knop, Filip Krag, 1 Jul 2010, In: The Journal of clinical endocrinology and metabolism. 95, 7, p. 3309-17 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Reduced incretin effect in type 2 diabetes: cause or consequence of the diabetic state?

    Knop, F. K., Vilsbøll, Tina, Højberg, P. V., Larsen, S., Madsbad, Sten, Vølund, A., Holst, Jens Juul & Krarup, T., 2007, In: Diabetes. 56, 8, p. 1951-9 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Reduced incretin effect precedes diabetes development following duodenopancreatectomy in individuals without diabetes

    Di Giuseppe, G., Soldovieri, L., Ciccarelli, G., Ferraro, P. M., Quero, G., Cinti, F., Capece, U., Moffa, S., Nista, E. C., Gasbarrini, A., Mari, A., Alfieri, S., Tondolo, V., Pontecorvi, A., Holst, Jens Juul, Giaccari, A. & Mezza, T., 2024, In: Journal of Clinical Investigation. 134, 8, 3 p., e175133.

    Research output: Contribution to journal › Comment/debate › Research

  23. Published

    Reduced insulinotropic effect of gastric inhibitory polypeptide in first-degree relatives of patients with type 2 diabetes

    Meier, J. J., Huking, K., Holst, Jens Juul, Deacon, Carolyn F., Schmiegel, W. H. & Nauck, M. A., 2001, In: Diabetes. 50, p. 2497-2504

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Reduced plasma levels of glucagon-like peptide-1 in elderly men are associated with impaired glucose tolerance but not with coronary heart disease

    Nathanson, D., Zethelius, B., Berne, C., Holst, Jens Juul, Sjöholm, A. & Nyström, T., 2009, In: Diabetologia. 53, 2, p. 277-80 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Reduced postprandial GLP-1 responses in women with gestational diabetes mellitus

    Bonde, L., Vilsbøll, Tina, Nielsen, T., Bagger, J. I., Svare, J. A., Holst, Jens Juul, Larsen, S. & Knop, Filip Krag, 13 Feb 2013, In: Diabetes, Obesity and Metabolism. 15, 8, p. 713-720 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Reduction in bone resorption by exogenous glucagon-like peptide-2 administration requires an intact gastrointestinal tract

    Gottschalck, I. B., Jeppesen, Palle Bekker, Holst, Jens Juul & Henriksen, D. B., Aug 2008, In: Scandinavian Journal of Gastroenterology. 43, 8, p. 929-37 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Reduction in bone resorption by exogenous glucagon-like peptide-2 administration requires an intact gastrointestinal tract

    Gottschalck, I. B., Jeppesen, Palle Bekker, Holst, Jens Juul & Henriksen, D. B., 2008, In: Scandinavian Journal of Gastroenterology. 43, 8, p. 929-937 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Reduction in cardiovascular risk factors and insulin dose, but no beta-cell regeneration 1 year after Roux-en-Y gastric bypass in an obese patient with type 1 diabetes: a case report

    Dirksen, C., Jacobsen, S. H., Bojsen-Møller, K. N., Jørgensen, N. B., Naver, L. S., Hvolris, L. E., Worm, Dorte, Madsbad, Sten, Holst, Jens Juul & Hansen, D. L., 7 Dec 2013, In: Obesity Research & Clinical Practice. 7, 4, p. e269-74 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Reduction of beta cell mass: partial insulin secretory compensation from the residual beta cell population in the nicotinamide-streptozotocin Göttingen minipig after oral glucose in vivo and in the perfused pancreas

    Larsen, M. O., Rolin, B., Gotfredsen, C. F., Carr, R. D. & Holst, Jens Juul, 2004, In: Diabetologia. 47, p. 1873-1878

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Reduction of hepatic insulin clearance after oral glucose ingestion is not mediated by glucagon-like peptide 1 or gastric inhibitory polypeptide in humans

    Meier, J. J., Holst, Jens Juul, Schmidt, W. E. & Nauck, M. A., Sep 2007, In: American Journal of Physiology: Endocrinology and Metabolism. 293, 3, p. E849-56

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Reduction of hepatic insulin clearance after oral glucose ingestion is not mediated by glucagon-like peptide 1 or gastric inhibitory polypeptide in humans

    Meier, J. J., Holst, Jens Juul, Schmidt, W. E. & Nauck, M. A., 2007, In: American Journal of Physiology: Endocrinology and Metabolism. 293, 3, p. E849-E856

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Reduction of insulinotropic properties of GLP-1 and GIP after glucocorticoid-induced insulin resistance

    Eriksen, M., Jensen, D. H., Tribler, S., Holst, Jens Juul, Madsbad, Sten & Krarup, T., 2015, In: Diabetologia. 58, 5, p. 920-8 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Reduction of nocturnal rise in bone resorption by subcutaneous GLP-2.

    Henriksen, D. B., Alexandersen, P., Byrjalsen, I., Hartmann, B., Bone, H. G., Christiansen, C. & Holst, Jens Juul, 2004, In: Bone. 34, 1, p. 140-7 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Reference intervals for glucose, beta-cell polypeptides, and counterregulatory factors during prolonged fasting

    Hojlund, K., Wildner-Christensen, M., Eshoj, O. & Holst, Jens Juul, 2001, In: Am J Physiol-Endoc M. 280, p. E50-E58

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Reference intervals for plasma glucose, insulin, proinsulin, C-peptide and counterregulatory factors during a 72-hour fast in healthy human subjects

    Højlund, K., Eshøj, O., Christensen, M. W., Skjærbæk, C., Frystyk, J., Holst, Jens Juul, Koldkjær, O., Møller J., D. & Beck-Nielsen, H., 2001, In: American Journal of Physiology.. 280, p. E50-E58

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Regulation of Pancreatic Alpha Cell Function and Proliferation by Bone Morphogenetic Protein 4 (BMP4) in vitro.

    Nielsen, S. S., Christensen, G. L., Holst, Jens Juul & Billestrup, Nils, Oct 2016, In: Endocrinology. 157, 10, p. 3809-3820 12 p., 27479530 .

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Regulation of Pancreatic α-Cell Function and Proliferation by Bone Morphogenetic Protein 4 (BMP4) In Vitro

    Nielsen, S. S., Christensen, G. L., Holst, Jens Juul & Billestrup, Nils, Oct 2016, In: Endocrinology. 157, 10, p. 3809-3820 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Regulation of glucagon secretion by incretins

    Holst, Jens Juul, Christensen, M., Lund, A., de Heer, J., Svendsen, B., Kielgast, U. & Knop, Filip Krag, Oct 2011, In: Diabetes, Obesity and Metabolism. 13 , Suppl 1, p. 89-94 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Regulation of gut hormone secretion. Studies using isolated perfused intestines.

    Svendsen, B. & Holst, Jens Juul, Mar 2016, In: Peptides. 77, p. 47-53 7 p.

    Research output: Contribution to journal › Review › Research › peer-review

  40. Published

    Regulation of secretion of pancreatic spasmolytic polypeptide from porcine pancreas

    Rasmussen, T. N., Harling, H., Thim, L., Pierzynowski, S., Weström, B. R. & Holst, Jens Juul, 1993, In: The American Journal of Physiology. p. G22-G29

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Regulation of urea synthesis during the acute-phase response in rats

    Thomsen, K. L., Jessen, N., Møller, A. B., Aagaard, N. K., Grønbæk, H., Holst, Jens Juul & Vilstrup, H., 1 Apr 2013, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 304, 7, p. G680-6 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Regulatory Peptides of the Gut

    Holst, Jens Juul, 1998, Small Bowel Disorders. Kluwer Academic Publishers

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  43. Published

    Regulatory peptides of the gastrointestinal tract

    Holst, Jens Juul, 2000, Small Bowel Disorders. London: Small Bowel Disorders, p. 96-115

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  44. Published

    Relationship between Optimum Mini‐doses of Glucagon and Insulin Levels when Treating Mild Hypoglycaemia in Patients with Type 1 Diabetes: A Simulation Study

    Ranjan, A., Wendt, S. L., Schmidt, S., Madsbad, Sten, Holst, Jens Juul, Madsen, H., Knudsen, C. B., Jørgensen, J. B. & Nørgaard, Kirsten, 2018, In: Basic & Clinical Pharmacology & Toxicology. 122, 3, p. 322-330

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Relationship between biochemical and symptomatic hypoglycemia after RYGB. Responses to a mixed meal test: a case-control study

    Søeby, M., Nielsen, J. B., Pedersen, S. B., Gribsholt, S. B., Holst, Jens Juul & Richelsen, B., 2020, In: Surgery for Obesity and Related Diseases. 16, 9, p. 1179-1185 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Relationships among tonic and episodic aspects of motivation to eat, gut peptides, and weight before and after bariatric surgery

    Bryant, E. J., King, N. A., Falkén, Y., Hellström, P. M., Holst, Jens Juul, Blundell, J. E. & Näslund, E., 12 Oct 2012, In: Surgery for Obesity and Related Diseases.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Release of PYY from pig intestinal mucosa; luminal and neural regulation

    Sheikh, S. P., Holst, Jens Juul, Ørskov, Cathrine, Ekman, R. & Schwartz, Thue W., Dec 1989, In: Regulatory Peptides. 26, 3, p. 253-66 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Release of galanin from isolated perfused porcine adrenal glands: role of splanchnic nerves

    Holst, Jens Juul, Ehrhart-Bornstein, M., Messell, T., Poulsen, Steen Seier & Harling, H., Jul 1991, In: American Journal of Physiology (Consolidated). 261, 1 Pt 1, p. E31-E40

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Release of galanin from isolated, perfused porcine adrenal glands. Role of the splanchnic nerves

    Holst, Jens Juul, Ehrhart-Bornstein, M. & Messell, T., 1991, In: Amer.J. Physiology. 261, p. E31-E40

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Release of glucagon-like peptide 1 (GLP-1 [7-36 amide]), gastric inhibitory polypeptide (GIP) and insulin in response to oral glucose after upper and lower intestinal resections

    Nauck, M. A., Siemsglüss, J., Ørskov, Cathrine & Holst, Jens Juul, Mar 1996, In: Zeitschrift fur Gastroenterologie. 34, 3, p. 159-66 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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