Jens Juul Holst

Jens Juul Holst

Professor

ORCID: 0000-0001-6853-3805

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  1. Published

    Secretion of glucose-dependent insulinotropic polypeptide in patients with type 2 diabetes: systematic review and meta-analysis of clinical studies

    Calanna, S., Christensen, Mikkel Bring, Holst, Jens Juul, Laferrère, B., Gluud, Lise Lotte, Vilsbøll, T. & Knop, Filip Krag, Oct 2013, In: Diabetes Care. 36, 10, p. 3346-52 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Secretion of incretin hormones (GIP and GLP-1) and incretin effect after oral glucose in first-degree relatives of patients with type 2 diabetes.

    Nauck, M. A., El-Ouaghlidi, A., Gabrys, B., Hücking, K., Holst, Jens Juul, Deacon, Carolyn F., Gallwitz, B., Schmidt, W. E. & Meier, J. J., 2004, In: Regulatory Peptides. 122, 3, p. 209-17 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Secretion of incretin hormones and the insulinotropic effect of gastric inhibitory polypeptide in women with a history of gestational diabetes

    Meier, J. J., Gallwitz, B., Askenas, M., Vollmer, K., Deacon, Carolyn F., Holst, Jens Juul, Schmidt, W. E. & Nauck, M. A., Sep 2005, In: Diabetologia. 48, 9, p. 1872-81 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Secretion of neurotensin from isolated perfused porcine ileum

    Holst Pedersen, J., Knuthsen, S., Bernabei, M., Ørskov, Cathrine & Holst, Jens Juul, May 1988, In: Regulatory Peptides. 21, 1-2, p. 13-9 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Secretion of pancreastatins from isolated, perfused porcine adrenal glands

    Børglum, T., Fahrenkrug, J. & Holst, Jens Juul, 1994, In: Peptides. 15, p. 519-527

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Secretion of pancreastatins from the porcine gastrointestinal tract

    Børglum, J. T., Holst, Jens Juul & Fahrenkrug, J., 1994, In: Scandinavian Journal of Gastroenterology. 29, p. 376-384

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Secretion of parathyroid hormone may be coupled to insulin secretion in humans

    Sass, M. R., Albrechtsen, Nicolai Jacob Wewer, Pedersen, Jens, Hare, Kristine Juul, Borbye-Lorenzen, N., Kiss, K., Vilsbøll, Tina, Knop, Filip Krag, Poulsen, Steen Seier, Jørgensen, Niklas Rye, Holst, Jens Juul, Ørskov, Cathrine & Hartmann, Bolette, 2020, In: Endocrine Connections. 9, 7, p. 747-754

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Secretion of the incretin hormones glucagon-like peptide-1 and gastric inhibitory polypeptide correlates with insulin secretion in normal man throughout the day

    Ørskov, Cathrine, Wettergren, A. & Holst, Jens Juul, Jul 1996, In: Scandinavian Journal of Gastroenterology. 31, 7, p. 665-70 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Secretion of trophic gut peptides is not different in bolus- and continuously fed piglets

    Goudoever, V., Stoll, B., Hartmann, B., Holst, Jens Juul, Reeds, P. J. & Burrin, D. G., 2001, In: J Nutr.. 131, p. 729-732

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Secretion, degradation, and elimination of glucagon-like peptide 1 and gastric inhibitory polypeptide in patients with chronic renal insufficiency and healthy control subjects.

    Meier, J. J., Nauck, M. A., Kranz, D., Holst, Jens Juul, Deacon, Carolyn F., Gaeckler, D., Schmidt, W. E. & Gallwitz, B., 2004, In: Diabetes. 53, 3, p. 654-62 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Selectivity of prandial glucose regulators: nateglinide, but not repaglinide, accelerates exocytosis in rat pancreatic A-cells

    Bokvist, K., Høy, M., Buschard, K., Holst, Jens Juul, Thomsen, M. K. & Gromada, J. L., 1999, In: Eur. J. Pharmacol.. 386, p. 105-111

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Semaglutide seems to be more effective the other GLP-1Ras

    Holst, Jens Juul & Madsbad, Sten, Dec 2017, In: Annals of Translational Medicine. 5, 24, 5 p., 505.

    Research output: Contribution to journal › Comment/debate › Research

  13. Published

    Sensing of triacylglycerol in the gut: different mechanisms for fatty acids and 2-monoacylglycerol

    Kleberg, K., Jacobsen, A. K., Ferreira, J. G., Windeløv, Johanne Agerlin, Rehfeld, Jens Frederik, Holst, Jens Juul, de Araujo, I. E. & Hansen, Harald S., 16 Jan 2015, In: The Journal of Physiology. 593, 8, p. 2097-109 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Separate and Combined Effects of GIP and GLP-1 Infusions on Bone Metabolism in Overweight Men without Diabetes

    Bergmann, N. C., Lund, A., Gasbjerg, Lærke Smidt, Jørgensen, N. R., Jessen, L., Hartmann, Bolette, Holst, Jens Juul, Christensen, Mikkel Bring, Vilsbøll, Tina & Knop, Filip Krag, Jul 2019, In: The Journal of clinical endocrinology and metabolism. 104, 7, p. 2953–2960

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Separate and Combined Glucometabolic Effects of Endogenous Glucose-Dependent Insulinotropic Polypeptide and Glucagon-like Peptide 1 in Healthy Individuals

    Gasbjerg, Lærke Smidt, Helsted, M. M., Hartmann, Bolette, Jensen, M. H., Gabe, M. B. N., wbf943, wbf943, Veedfald, Simon, Stensen, S., Lanng, A. R., Bergmann, N. C., Christensen, Mikkel Bring, Vilsbøll, Tina, Holst, Jens Juul, Rosenkilde, Mette & Knop, Filip Krag, 2019, In: Diabetes. 68, 3, p. 906-917

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Separate effects of glucagon like peptide-2 (GLP-2) and glucose-dependent insulinotropic polypeptide (GIP) on bone remodelling

    Skov-Jeppesen, Kirsa, Svane, M., Martinussen, C., Gabe, M., Gasbjerg, Lærke Smidt, Madsbad, Sten, Holst, Jens Juul, Rosenkilde, Mette & Hartmann, Bolette, 2018, In: Diabetologia. 61, S1, p. S245-S245 501.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  17. Published

    Separate impact of obesity and glucose tolerance on the incretin effect in normal subjects and type 2 diabetic patients

    Muscelli, E., Mari, A., Casolaro, A., Camastra, S., Seghieri, G., Gastaldelli, A., Holst, Jens Juul & Ferrannini, E., May 2008, In: Diabetes. 57, 5, p. 1340-8 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Separate impact of obesity and glucose tolerance on the incretin effect in normal subjects and type 2 diabetic patients

    Muscelli, E., Mari, A., Casolaro, A., Camastra, S., Seghieri, G., Gastaldelli, A., Holst, Jens Juul & Ferrannini, E., 2008, In: Diabetes. 57, 5, p. 1340-1348 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Serum bile acids are higher in humans with prior gastric bypass: potential contribution to improved glucose and lipid metabolism

    Patti, M., Houten, S. M., Bianco, A. C., Bernier, R., Larsen, P. R., Holst, Jens Juul, Badman, M. K., Maratos-Flier, E., Mun, E. C., Pihlajamaki, J., Auwerx, J. & Goldfine, A. B., 2009, In: Obesity. 17, 9, p. 1671-7 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Serum lipase activity and concentration during intravenous infusions of GLP-1 and PYY3-36 and after ad libitum meal ingestion in overweight men

    Schmidt, J. B., Sjödin, Anders Mikael, Stevner, L. S., Ritz, C., Michaelsen, N. B., Thomsen, A. B., Holst, Jens Juul & Astrup, A., 2016, In: Physiological Reports. 4, 18, 7 p., e12980.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Severe hypoglycaemia post-gastric bypass requiring partial pancreatectomy: evidence for inappropriate insulin secretion and pancreatic islet hyperplasia

    Patti, M. E., McMahon, G., Mun, E. C., Bitton, A., Holst, Jens Juul, Goldsmith, J., Hanto, D. W., Callery, M., Arky, R., Nose, V., Bonner-Weir, S. & Goldfine, A. B., Nov 2005, In: Diabetologia. 48, 11, p. 2236-40 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Severe hypoglycemia post-gastric bypass requiring partial pancreatectomy: Evidence for inappropriate insulin secretion and pancreatic islet cell hyperplasia

    Patti, M. E., Mun, E. C., Holst, Jens Juul, Hanto, D. W., Goldsmith, J., Arky, R., Nose, V., Bonner-Weir, S. & Goldfine, A. B., 2005, In: Diabetologia. 48, p. 2236-2240

    Research output: Contribution to journal › Journal article › Research

  23. Published

    Sex steroids affect triglyceride handling, glucose-dependent insulinotropic polypeptide, and insulin sensitivity: a 1-week randomized clinical trial in healthy young men

    Lapauw, B., Ouwens, M., 't Hart, L. M., Wuyts, B., Holst, Jens Juul, T'Sjoen, G., Kaufman, J. & Ruige, J. B., 1 Aug 2010, In: Diabetes Care. 33, 8, p. 1831-3 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Short bowel patients treated for two years with glucagon-like Peptide 2: effects on intestinal morphology and absorption, renal function, bone and body composition, and muscle function

    Jeppesen, Pia, Lund, P., Gottschalck, I. B., Nielsen, H. B., Holst, Jens Juul, Mortensen, J., Poulsen, S. S., Quistorff, B. & Mortensen, P. B., 2009, In: Gastroenterology Research and Practice. 2009, p. 616054

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Short bowel patients treated for two years with glucagon-like peptide 2 (GLP-2): compliance, safety, and effects on quality of life

    Jeppesen, Palle Bekker, Lund, P., Gottschalck, I. B., Nielsen, H. B., Holst, Jens Juul, Mortensen, J., Poulsen, S. S., Quistorff, B. & Mortensen, P. B., 2009, In: Gastroenterology Research and Practice. 2009, p. 425759

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Short communication: Promotion of glucagon-like peptide-2 secretion in dairy calves with a bioactive extract from Olea europaea

    Morrison, S. Y., Pastor, J. J., Quintela, J. C., Holst, Jens Juul, Hartmann, Bolette, Drackley, J. K. & Ipharraguerre, I. R., 1 Mar 2017, In: Journal of Dairy Science. 100, 3, p. 1940-1945 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Short term insulin treatment prevents the diabetogenic action of streptozotocin in rats

    Thulesen, J., Ørskov, Cathrine, Holst, Jens Juul & Poulsen, Steen Seier, 1997, In: Endokrinologiya. Vol. 138, No. 1, p. 62-68

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Short-chain fatty acids and regulation of pancreatic endocrine secretion in mice

    Ørgaard, A., Jepsen, Sara Lind & Holst, Jens Juul, 2019, In: Islets. 11, 5, p. 103-111

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Short-term administration of Glucagon-like peptide-2. Effects on bone mass density and markers of bone remodelling in short bowel patients with no colon

    Haderslev, K. V., Jeppesen, P. B., Hartmann, B., Thulesen, J., Sørensen, H. A., Graff, J., Hansen, B. S., Tofteng, F., Poulsen, Steen Seier, Madsen, J. L., Holst, Jens Juul, Staun, M. & Mortensen, P. B., 2002, In: Scandinavian Journal of Gastroenterology. vol. 37, p. 392-398

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Short-term administration of glucagon-like peptide-2. Effects on bone mineral density and markers of bone turnover in short-bowel patients with no colon

    Haderslev, Kent Valentin, Jeppesen, Palle Bekker, Hartmann, Bolette, Thulesen, J., Sorensen, H. A., Graff, J., Tofteng, F., Poulsen, S. S., Madsen, J. L., Holst, Jens Juul, Staun, Michael, Mortensen, P. B. & Poulsen, Steen Seier, 1 Apr 2002, In: Scandinavian Journal of Gastroenterology. 37, 4, p. 392-8 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Short-term effects of a low carbohydrate diet on glycaemic variables and cardiovascular risk markers in patients with type 1 diabetes: A randomized open-label crossover trial

    Ranjan, A., Schmidt, S., Damm-Frydenberg, C., Holst, Jens Juul, Madsbad, Sten & Nørgaard, Kirsten, Oct 2017, In: Diabetes, Obesity and Metabolism. 19, 10, p. 1479-1484

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Short-term effects of liraglutide on kidney function and vasoactive hormones in type 2 diabetes: a randomized clinical trial

    Skov, J., Pedersen, M., Holst, Jens Juul, Madsen, B., Goetze, Jens P. , Rittig, S., Jonassen, Thomas, Frøkiær, J., Dejgaard, A. & Christiansen, J. S., 22 Feb 2016, In: Diabetes, Obesity and Metabolism Online. 18, 6, p. 581-9 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Short-term insulin treatment prevents the diabetogenic action of streptozotocin in rats

    Thulesen, J., Ørskov, Cathrine, Holst, Jens Juul & Poulsen, Steen Seier, Jan 1997, In: Endocrinology. 138, 1, p. 62-68 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Short-term treatment with GLP-1 increases pulsatile secretion in type 2 diabetes with no effect on orderliness.

    Juhl, C. B., Schmitz, O., Holst, Jens Juul, Vedhuis, J. & Pørksen, N., 2000, In: Diabetologia. 43, p. 583-588

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Short-term treatment with olanzapine does not modulate gut hormone secretion: olanzapine disintegrating versus standard tablets

    Vidarsdottir, S., Roelfsema, F., Streefland, T., Holst, Jens Juul, Rehfeld, Jens Frederik & Pijl, H., 2009, In: European Journal of Endocrinology. 162, 1, p. 75-83 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Signs of Glucagon Resistance After a Two-Week Hypercaloric Diet Intervention

    Suppli, M. P., Høgedal, A., Bagger, J. I., Chabanova, E., van Hall, Gerrit, Forman, Julie Lyng, Christensen, Mikkel Bring, Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul & Knop, Filip Krag, 2024, In: Journal of Clinical Endocrinology and Metabolism. 109, 4, p. 955–967 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Signs of a Glucose- and Insulin-Independent Gut-Bone Axis and Aberrant Bone Homeostasis in Type 1 Diabetes

    Hartmann, Bolette, Longo, M., Mathiesen, D. S., Hare, Kristine Juul, Jørgensen, Niklas Rye, Esposito, K., Deacon, Carolyn F., Vilsbøll, Tina, Holst, Jens Juul & Knop, Filip Krag, 2024, In: Journal of Clinical Endocrinology and Metabolism. 109, 1, p. e259-e265 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Similar elimination rates of GLP-1 in obese type 2 diabetic patients and matched healthy subjects

    Vilsbøll, T., Krarup, T., Agersø, H. & Holst, Jens Juul, 2003, In: J. Clin. Endocrinol. Metab.. 88, p. 220-224

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Similar elimination rates of glucagon-like peptide-1 in obese type 2 diabetic patients and healthy subjects

    Vilsbøll, T., Agersø, H., Krarup, T. & Holst, Jens Juul, Jan 2003, In: The Journal of clinical endocrinology and metabolism. 88, 1, p. 220-4 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Similar gastric emptying but greater gastric secretion and GIP release after the ingestion of peptide hydrolysates in man

    Calbet, J. A. L. & Holst, Jens Juul, 2004, In: Eur J Nutrition. 43, p. 127-139

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Similar incretin secretion in obese and non-obese Japanese subjects with type 2 diabetes

    Kozawa, J., Okita, K., Imagawa, A., Iwahashi, H., Holst, Jens Juul, Yamagata, K. & Shimomura, I., 12 Mar 2010, In: Biochemical and Biophysical Research Communications. 393, 3, p. 410-3 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Similar insulin secretory response to a gastric inhibitory polypeptide bolus injection at euglycemia in first-degree relatives of patients with type 2 diabetes and control subjects.

    Meier, J. J., Nauck, M. A., Siepmann, N., Greulich, M., Holst, Jens Juul, Deacon, Carolyn F., Schmidt, W. E. & Gallwitz, B., 2003, In: Metabolism - Clinical and Experimental. 52, 12, p. 1579-85 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Similar weight-adjusted insulin secretion and insulin sensitivity in short-duration late autoimmune diabetes of adulthood (LADA) and Type 2 diabetes: Action LADA 8

    Juhl, C. B., Bradley, U., Holst, Jens Juul, Leslie, R. D., Yderstraede, K. B., Hunter, S. & Action LADA Consortium, A. L. C., 15 Mar 2014, In: Diabetic Medicine. 31, 8, p. 941-945

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Single-Dose Metformin Enhances Bile Acid-Induced Glucagon-Like Peptide-1 Secretion in Patients With Type 2 Diabetes

    Brønden, A., Albér, A., Rohde, U., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, Nov 2017, In: The Journal of clinical endocrinology and metabolism. 102, 11, p. 4153-4162 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Sitagliptin, a dipeptidyl peptidase-4 inhibitor, in patients with short bowel syndrome and colon in continuity: an open-label pilot study

    Naimi, R. M., Hvistendahl, M. K., Thomassen, L. M., Johnsen, H., Christiansen, Charlotte Bayer, Holst, Jens Juul, Hartmann, Bolette & Jeppesen, Palle Bekker, 2021, In: BMJ Open Gastroenterology. 8, 1, 10 p., e000604.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Six-day sc GIP infusion increases plasma NEFA without altering the adipose tissue transcriptome, GIPR levels or plasma markers of inflammation in patients with type 1 diabetes

    Heimburger, S. M. N., Hoe, B., Nielsen, C. N., Hartmann, Bolette, Holst, Jens Juul, Dela, Flemming, Overgaard, J., Størling, Joachim, Vilsbøll, Tina, Dejgaard, T. F., Pyke, C., Christensen, M. B. & Knop, Filip Krag, 2021, In: Diabetologia. 64, SUPPL 1, p. 258-258 494.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  47. Published

    Six-day subcutaneous GIP infusion increases glycaemic time in range in patients with type 1 diabetes

    Heimbuerger, S. M. N., Hoe, B., Nielsen, C. N., Bergmann, N. C., Hartmann, Bolette, Holst, Jens Juul, Størling, Joachim, Vilsbøll, Tina, Dejgaard, T. F., Christensen, Mikkel Bring & Knop, Filip Krag, 2020, In: Diabetologia. 63, SUPPL 1, p. S73 1 p., 145.

    Research output: Contribution to journal › Conference abstract in journal › Research

  48. Published

    Small intestinal dysfunction accompanies the complex endocrinopathy of human proprotein convertase 1 deficiency

    Jackson, R. S., Creemers, J. W. M., Saraf Faraoqi, I., Raffin-Sanson, M. L., Varro, A., Dockray, G. J., Holst, J. J., Brubaker, P. L., Corvol, P., Polonsky, K. S., Ostrega, D., Becker, K. L., Bertagna, X., Hutton, J. C., White, A., Dattani, M. T., Hussain, K., Middleton, S. J., Nicholl, T. M., Lindley, K. J. & 1 others, O Rahlly, S., 2003, In: J. Clin. Invest.. 112, p. 1550-1560

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Small molecule ago-allosteric modulators of the human glucagon-like peptide-1 (hGLP-1) receptor

    Teng, M., Johnson, M. D., Thomas, C., Kiel, D., Lakis, J. N., Kercher, T., Aytes, S., Kostrowicki, J., Bhumralkar, D., Truesdale, L., May, J., Sidelman, U., Kodra, J. T., Jørgensen, A. S., Olesen, P. H., Jong, J. C. D., Madsen, P., Behrens, C., Pettersson, I., Knudsen, L. B. & 2 others, Holst, Jens Juul & Lau, J., 2007, In: Bioorganic & Medicinal Chemistry Letters. 17, 19, p. 5472-5478 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Small-intestinal dysfunction accompanies the complex endocrinopathy of human proprotein convertase 1 deficiency

    Jackson, R. S., Creemers, J. W. M., Farooqi, I. S., Raffin-Sanson, M-L., Varro, A., Dockray, G. J., Holst, J. J., Brubaker, P. L., Corvol, P., Polonsky, K. S., Ostrega, D., Becker, K. L., Bertagna, X., Hutton, J. C., White, A., Dattani, M. T., Hussain, K., Middleton, S. J., Nicole, T. M., Milla, P. J. & 2 others, Lindley, K. J. & O'Rahilly, S., Nov 2003, In: The Journal of Clinical Investigation. 112, 10, p. 1550-60 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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