Jens Juul Holst
Professor
Endocrinology and Metabolism
Blegdamsvej 3
2200 København N.
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The effect of Glucagon-Like Peptide-2 on mesenteric blood flow and cardiac parameters in end-jejunostomy short bowel patients
Bremholm, L., Hornum, Mads, Andersen, U. B., Hartmann, Bolette, Holst, Jens Juul & Jeppesen, Palle Bekker, 2011, In: Regulatory Peptides. 168, 1-3, p. 32-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The effect of Roux-en-Y gastric bypass surgery on energy expenditure and appetite: a randomized human study including “pair fed” control subjects
Schmidt, J. B., Gregersen, N. T., Pedersen, S., Nielsen, M. S., Nielsen, L. V., Holst, Jens Juul, Hansen, D. L., Dorm, D. W., Madsbad, Sten, Clausen, T. R. C., Ritz, C., Astrup, A. & Sjödin, Anders Mikael, 2013, In: Obesity Facts. 6, suppl. 1, p. 28 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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The effect of a glucagon-like peptide-1 receptor agonist on glucose tolerance in women with previous gestational diabetes mellitus: protocol for an investigator-initiated, randomised, placebo-controlled, double-blinded, parallel intervention trial
Foghsgaard, S., Vedtofte, L., Mathiesen, Elisabeth, Svare, J. A., Gluud, Lise Lotte, Holst, Jens Juul, Damm, Peter, Knop, Filip Krag & Vilsbøll, T., 2013, In: B M J Open. 3, 10, p. 1-8 9 p., e003834.Research output: Contribution to journal › Journal article › Research › peer-review
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The effect of a high monounsaturated fatty acid, low glycemic index diet and a low fat diet on satiety, appetite regulatory hormones and glucose metabolism during a 6 mo weight maintenance period
Sloth, B., Due, A. P., Larsen, T. M., Holst, Jens Juul, Heding, A. & Astrup, A., 2008, In: International Journal of Obesity. 32, Suppl. 1, p. S204 1 p.Research output: Contribution to journal › Conference abstract in journal › Research
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The effect of a high-MUFA, low-glycaemic index diet and a low-fat diet on appetite and glucose metabolism during a 6-month weight maintenance period
Sloth, B., Due, A. P., Larsen, T. M., Holst, Jens Juul, Heding, A. & Astrup, A., 2008, In: British Journal of Nutrition. 101, 12, p. 1846-1858 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The effect of a subcutaneous infusion of GLP-1, OXM and PYY on Energy intake and Expenditure in Obese volunteers
Tan, T., Behary, P., Tharakan, G., Minnion, J., Al-Najim, W., Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul & Bloom, S. R., 1 Jul 2017, In: The Journal of clinical endocrinology and metabolism. 102, 7, p. 2364-2372 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The effect of a very low calorie diet on insulin sensitivity, beta cell function, insulin clearance, incretin hormone secretion, androgen levels and body composition in obese young women
Svendsen, P. F., Jensen, F. K., Holst, Jens Juul, Haugaard, Steen Bendix, Nilas, L. & Madsbad, Sten, Sep 2012, In: Scandinavian Journal of Clinical & Laboratory Investigation. 72, 5, p. 410-9 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The effect of acute dual SGLT1/SGLT2 inhibition on incretin release and glucose metabolism after gastric bypass surgery
Martinussen, C., Veedfald, Simon, Dirksen, Carsten Moro, Bojsen-Møller, K. N., Svane, M. S., Albrechtsen, Nicolai Jacob Wewer, van Hall, Gerrit, Kristiansen, V. B., Fenger, M., Holst, Jens Juul & Madsbad, Sten, 2020, In: American Journal of Physiology: Endocrinology and Metabolism. 318, 6, p. E956-E964 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The effect of casein, hydrolyzed casein, and whey proteins on urinary and postprandial plasma metabolites in overweight and moderately obese human subjects
Schmedes, M. S., Bendtsen, L. Q., Gomes, S., Liaset, B., Holst, Jens Juul, Ritz, C., Reitelseder, S., Sjödin, Anders Mikael, Astrup, A., Young, J. F., Sundekilde, U. K. & Bertram, H. C., 2018, In: Journal of the Science of Food and Agriculture. 98, 15, p. 5598-5605 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The effect of curcumin on hepatic fat content in individuals with obesity
Hellmann, P. H., Bagger, J. I., Carlander, K. R., Forman, Julie Lyng, Chabanova, E., Svenningsen, J. S., Holst, Jens Juul, Gillum, M. P., Vilsbøll, Tina & Knop, Filip Krag, 2022, In: Diabetes, Obesity and Metabolism. 24, 11, p. 2192-2202 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The effect of dietary carbohydrate restriction beyond weight loss on health-related quality of life and cognition
Jensen, N. J., Wodschow, H. Z., fbg982, fbg982, Samkani, A., Astrup, A., Frystyk, J., Hartmann, Bolette, Holst, Jens Juul, Larsen, T. M., Madsbad, Sten, Magkos, Faidon, Miskowiak, Kamilla, Rungby, Jørgen, Haugaard, Steen Bendix & Thomsen, M. N., 2021, In: Diabetologia. 64, SUPPL 1, p. 62-63 114.Research output: Contribution to journal › Conference abstract in journal › Research
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The effect of dietary fish oil in addition to lifestyle counselling on lipid oxidation and body composition in slightly overweight teenage boys
Pedersen, M. H., Mølgaard, Christian, Hellgren, L., Matthiessen, J., Holst, Jens Juul & Lauritzen, Lotte, 2011, In: Journal of Nutrition and Metabolism. 2011, 348368, 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The effect of exogenous glucagon on circulating amino acids in individuals with and without type 2 diabetes and obesity
Grøndahl, M. F. G., Bagger, J. I., Suppli, M. P., van Hall, Gerrit, Albrechtsen, Nicolai Jacob Wewer, Holst, Jens Juul, Vilsbøll, Tina, Christensen, Mikkel Bring, Lund, A. B. & Knop, Filip Krag, 2024, In: Endocrine Connections. 13, 3, 7 p., e230516.Research output: Contribution to journal › Journal article › Research › peer-review
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The effect of glucagon-like Peptide-2 receptor agonists on colonic anastomotic wound healing
Redstone, H. A., Buie, W. D., Hart, D. A., Wallace, L., Hornby, P. J., Sague, S., Holst, Jens Juul & Sigalet, D. L., 1 Jan 2010, In: Gastroenterology Research and Practice. 2010, p. Article ID 672453 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The effect of glucagon-like peptide 1 on cardiovascular risk
Sivertsen, J., Rosenmeier, J., Holst, Jens Juul & Vilsbøll, T., Apr 2012, In: Nature Reviews Cardiology. 9, 4, p. 209-22 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The effect of glucagon-like peptide-1 on energy expenditure and substrate metabolism in humans
Flint, A., Raben, A., Rehfeld, J. F., Holst, Jens Juul & Astrup, A., 2000, In: International Journal of Obesity. 24, p. 288-298Research output: Contribution to journal › Journal article › Research › peer-review
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The effect of glucagon-like peptide-2 on arterial blood flow and cardiac parameters
Bremholm, L., Hornum, Mads, Andersen, U. B. & Holst, Jens Juul, 8 Jan 2010, In: Regulatory Peptides. 159, 1-3, p. 67-71 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The effect of glucose on the plasma concentration of somatostatin during caloric deficiency in man
Øktedalen, O., Opstad, P. K. & Holst, Jens Juul, 1993, In: Scandinavian Journal of Gastroenterology. 28, p. 652-656Research output: Contribution to journal › Journal article › Research
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The effect of melatonin on incretin hormones: results from experimental and randomized clinical studies
Lauritzen, E. S., Støy, J., Bæch-Laursen, C., Grarup, Niels, Jessen, N., Hansen, Torben, Møller, N., Hartmann, Bolette, Holst, Jens Juul & Kampmann, U., 2021, In: Journal of Clinical Endocrinology and Metabolism. 106, 12, p. e5109-e5123 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The effect of preceding glucose decline rate on low-dose glucagon efficacy in individuals with type 1 diabetes: A randomized crossover trial
Laugesen, C., Schmidt, S., Holst, Jens Juul, Nørgaard, Kirsten & Ranjan, A. G., 2021, In: Diabetes, Obesity and Metabolism. 23, 4, p. 1057-1062 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The effect of salatrim, a low-calorie modified triacylglycerol, on appetite and energy intake
Sørensen, L. B., Cueto, H. T., Andersen, M. T., Bitz, C., Holst, Jens Juul, Rehfeld, Jens Frederik & Astrup, A., 2008, In: American Journal of Clinical Nutrition. 87, 5, p. 1163-1169 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The effects of L-arabinose on intestinal sucrase activity: dose-response studies in vitro and in humans
Krog-Mikkelsen, I., Hels, O., Tetens, Inge , Holst, Jens Juul, Andersen, Jens Rikardt & Bukhave, K., 2011, In: American Journal of Clinical Nutrition. 94, 2, p. 472-478 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The effects of TNF-α on GLP-1-stimulated plasma glucose kinetics
Lehrskov-Schmidt, L., Lehrskov-Schmidt, L., Nielsen, S. T., Holst, Jens Juul, Møller, K. & Solomon, T. P. J., Apr 2015, In: The Journal of clinical endocrinology and metabolism. 100, 4, p. E616-E622 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The effects of dietary fibre type on satiety-related hormones and voluntary food intake in dogs
Bosch, G., Verbrugghe, A., Hesta, M., Holst, Jens Juul, van der Poel, A. F. B., Janssens, G. P. J. & Hendriks, W. H., 2009, In: British Journal of Nutrition. 102, 2, p. 318-25 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The effects of duodenal peptides on glucagon-like peptide-1 secretion from the ileum. A duodeno--ileal loop?
Hansen, L. & Holst, Jens Juul, 31 Dec 2002, In: Regulatory Peptides. 110, 1, p. 39-45 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The effects of exercise-induced weight loss on appetite-related peptides and motivation to eat
Martins, C., Kulseng, B., King, N. A., Holst, Jens Juul & Blundell, J. E., 1 Apr 2010, In: Journal of Clinical Endocrinology and Metabolism. 95, 4, p. 1609-16 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The effects of gastric emptying on the postprandial ghrelin response
Blom, W., Lluch, A., Vinoy, S., Stafleu, A., Van den Berg, R., Holst, Jens Juul, Kok, F. J. & Hendriks, H. F. K., 2006, In: Am. J. Physiol.. 290, p. E389-E395Research output: Contribution to journal › Journal article › Research
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The effects of postprandial exercise and meal glycemic index on plasma glucose and glucoregulatory hormone responses after Roux-en-Y gastric bypass
Ternhamar, T., Møller, A., Martinussen, C., Svane, M. S., Hindsø, M., Jørgensen, N. B., Dirksen, C., Jensen, Jens-Erik Beck, Hartmann, Bolette, Holst, Jens Juul, Kiens, Bente, Madsbad, Sten & Bojsen-Møller, K. N., 2023, In: American journal of physiology. Endocrinology and metabolism. 325, 5, p. E540-E551 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The effects of variations in dose and method of administration on glucagon like peptide-2 activity in the rat
Kaji, T., Tanaka, H., Holst, Jens Juul, Redstone, H., Wallace, L., Heuval, E. D. & Sigalet, D. L., 2008, In: European Journal of Pharmacology. 596, 1-3, p. 138-145 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The effects of variations in dose and method of administration on glucagon like peptide-2 activity in the rat
Kaji, T., Tanaka, H., Holst, Jens Juul, Redstone, H., Wallace, L., de Heuval, E. & Sigalet, D. L., 31 Oct 2008, In: European Journal of Pharmacology. 596, 1-3, p. 138-45 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The elimination rates of intact GIP as well as its primary metabolite, GIP 3-42, are similar in type 2 diabetic patients and healthy subjects.
Vilsbøll, Tina, Agersø, H., Lauritsen, T., Deacon, Carolyn F., Aaboe, K., Madsbad, Sten, Krarup, T. & Holst, Jens Juul, 2006, In: Regulatory Peptides. 137, 3, p. 168-72 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The ethanol augmentation of glucose-induced insulin secretion is abolished by calcium antagonism with nifedipine: No evidence for a role of glucagon-like peptide-1 (GLP-1)
Svartberg, J., Holst, Jens Juul, Gutniak, M. K. & Adner, N., 1998, In: Pancreas. 16, p. 66-71Research output: Contribution to journal › Journal article › Research › peer-review
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The exaggerated glucagon-like peptide-1 response is important for the improved β-cell function and glucose tolerance after Roux-en-Y gastric bypass in patients with type 2 diabetes
Jørgensen, N. B., Dirksen, C., Bojsen-Møller, K. N., Jacobsen, S. H., Worm, Dorte, Hansen, D. L., Kristiansen, V. B., Naver, L., Madsbad, Sten & Holst, Jens Juul, 6 May 2013, In: Diabetes. 62, 9, p. 3044-3052 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The expanding incretin universe: from basic biology to clinical translation
Drucker, D. J. & Holst, Jens Juul, 2023, In: Diabetologia. 66, p. 1765-1779Research output: Contribution to journal › Review › Research › peer-review
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The feedback cycles between glucose, amino acids and lipids and alpha cell secretion and their role in metabolic fatty liver disease
Winther-Sørensen, Marie, Holst, Jens Juul & Albrechtsen, Nicolai Jacob Wewer, 2023, In: Current Opinion in Lipidology. 34, 1, p. 27-31Research output: Contribution to journal › Review › Research › peer-review
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The gastric acid secretagogue gastrin-releasing peptide and the inhibitor oxyntomodulin do not exert their effect directly on the parietal cell in the rat
Poulsen, Steen Seier & Holst, Jens Juul, 1988, In: Digestion. 40, 3, p. 144-51 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The glucagon like peptide-2 'axis': Capacity for production and response following intestinal resection or repair of gastroschisis in infants
Sigalet, D. L., Lam, V., Brindle, M., Boctor, D., Wallace, L., de Heuval, E., Hartmann, Bolette & Holst, Jens Juul, 2018, In: Journal of Pediatric Surgery. 53, 5, p. 898-904Research output: Contribution to journal › Journal article › Research › peer-review
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The glucagon receptor antagonist LY2409021 does not affect gastrointestinal-mediated glucose disposal or the incretin effect in individuals with and without type 2 diabetes
Hædersdal, S., Lund, A., Nielsen-Hannerup, E., Maagensen, H., Forman, Julie Lyng, Holst, Jens Juul, Knop, Filip Krag & Vilsbøll, Tina, 2022, In: European Journal of Endocrinology. 187, 4, p. 507-518 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The glucagon-like peptide 2 receptor is expressed in enteric neurons and not in the epithelium of the intestine
Pedersen, Jens, B. Pedersen, N., Brix, S. W., Grunddal, Kaare Villum, Rosenkilde, Mette, Hartmann, Bolette, Ørskov, Cathrine, Poulsen, Steen Seier & Holst, Jens Juul, May 2015, In: Peptides. 67, p. 20-28 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The glucagon-like peptide-1 metabolite GLP-1-(9-36) amide reduces postprandial glycemia independently of gastric emptying and insulin secretion in humans.
Meier, J. J., Gethmann, A., Nauck, M. A., Götze, O., Schmitz, F., Deacon, Carolyn F., Gallwitz, B., Schmidt, W. E. & Holst, Jens Juul, 2006, In: American Journal of Physiology: Endocrinology and Metabolism. 290, 6, p. E1118-23Research output: Contribution to journal › Journal article › Research › peer-review
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The glucagon-like peptide-1 receptor agonist liraglutide reduces jejunostomy output and improves intestinal absorption in short bowel syndrome patients with intestinal failure: A pilot study
Hvistendahl, M., Brandt, C. F., Tribler, S., Naimi, R., Hartmann, B., Holst, Jens Juul, Rehfeld, Jens Frederik, Hornum, M., Andersen, Jens Rikardt, Mortensen, P. B. & Jeppesen, P. B., 2015. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
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The glucagonostatic and insulinotropic effects of glucagon-like peptide 1 contribute equally to its glucose-lowering action
Hare, K. J., Vilsbøll, Tina, Asmar, M., Deacon, Carolyn F., Knop, Filip Krag & Holst, Jens Juul, 1 Jul 2010, In: Diabetes. 59, 7, p. 1765-70 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The glucose-lowering effect of the bile acid sequestrant sevelamer in patients with type 2 diabetes is not mediated by glucagon-like peptide 1
Nerild, H. H., Brønden, Andreas, Haddouchi, A. E., Holst, Jens Juul, Sonne, D. P., Vilsbøll, Tina & Knop, Filip Krag, 2021, In: Diabetologia. 64, SUPPL 1, p. 217-217 422.Research output: Contribution to journal › Conference abstract in journal › Research
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The glycemic, insulinemic and plasma amino acid responses to equi-carbohydrate milk meals, a pilot- study of bovine and human milk
Gunnerud, U., Holst, Jens Juul, Östman, E. & Björck, I., 2012, In: Nutrition Journal. 11, p. 83Research output: Contribution to journal › Journal article › Research › peer-review
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The hypothalamic satiety peptide CART is expressed in anorectic and non-anorectic pancreatic islet tumors and in the normal islet of Langerhans
Jensen, P. B., Kristensen, P., Clausen, J. T., Judge, M. E., Hastrup, S., Thim, L., Wulff, B. S., Foged, C., Jensen, J., Holst, Jens Juul & Madsen, O. D., 1999, In: FEBS Letters. 447, p. 139-143Research output: Contribution to journal › Journal article › Research › peer-review
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The impact of EndoBarrier gastrointestinal liner in obese patients with normal glucose tolerance and in patients with type 2 diabetes
Rohde, U., Federspiel, C. A., Vilmann, Peter, Langholz, Ebbe, Friis, S. U., Krakauer, M., Rehfeld, Jens Frederik, Holst, Jens Juul, Vilsbøll, Tina & Knop, Filip Krag, Feb 2017, In: Diabetes, Obesity and Metabolism. 19, 2, p. 189-199 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The impact of acute fluctuations in plasma glucose on echocardiographic derived measures of systolic function in patients with type 1 diabetes
Andreasen, C. R., Andersen, A., Haqelqvist, P. G., Abelin, K., Lauritsen, J. V., Jorgensen, P. G., Engberg, S., Faber, Jens, Holst, Jens Juul, Pedersen-Bjergaard, Ulrik, Knop, Filip Krag & Vilsbøll, Tina, 2021, In: Diabetologia. 64, SUPPL 1, p. 135-136 2 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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The impact of acute glycaemic fluctuations on left ventricular systolic function in insulin-treated type 2 diabetes
Andersen, A., Jorgensen, P. G., Bagger, J. I., Baldassarre, M. P. A., Christensen, M., Abelin, K. U., Faber, Jens, Pedersen-Bjergaard, Ulrik, Holst, Jens Juul, Lindhardt, T., Gislason, Gunnar Hilmar, Knop, Filip Krag & Vilsbøll, Tina, 2020, In: Diabetologia. 63, SUPPL 1, p. S429-S429 897.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
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The impact of dipeptidyl peptidase 4 inhibition on incretin effect, glucose tolerance, and gastrointestinal-mediated glucose disposal in healthy subjects
Rhee, N. A., Østoft, S. H., Holst, Jens Juul, Deacon, Carolyn F., Vilsbøll, T. & Knop, Filip Krag, 16 Jun 2014, In: European Journal of Endocrinology. 171, 3, p. 353-362 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The impact of pancreatic enzyme supplementation on postprandial responses of glucagon-like Peptide-2 in patients with chronic pancreatitis and pancreatic exocrine insufficiency
Knop, Filip Krag, Vilsbøll, Tina, Lund, A., Krarup, T., Holst, Jens Juul & Hornum, Mads, 6 Sep 2010, In: Journal of the Pancreas. 11, 5, p. 489-91 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 4207
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Meal induced gut hormone secretion is altered in aerobically trained compared to sedentary young healthy males
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Copenhagen study of overweight patients with coronary artery disease undergoing low energy diet or interval training: the randomized CUT-IT trial protocol
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Whole grain-rich diet reduces body weight and systemic low-grade inflammation without inducing major changes of the gut microbiome: a randomised cross-over trial
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