Thue W. Schwartz

Thue W. Schwartz

Professor

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    ORCID: 0000-0002-0261-6904

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    1. Published

      Selective recognition of the membrane-bound CXC3 chemokine, fractal by the human cytomegalovirus-encoded broad-spectrum receptor US28

      Kledal, T. N., Rosenkilde, Mette & Schwartz, Thue W., 1998, In: FEBS Letters. 441, p. 209-214

      Research output: Contribution to journal › Journal article › Research › peer-review

    2. Published

      Self-organized metabotyping of obese individuals identifies clusters responding differently to bariatric surgery

      Lappa, D., Meijnikman, A. S., Krautkramer, K. A., Olsson, L. M., Aydin, Ö., Van Rijswijk, A. S., Acherman, Y. I. Z., De Brauw, M. L., Tremaroli, V., Olofsson, L. E., Lundqvist, A., Hjorth, Siv Annegrethe, Ji, B., Gerdes, V. E. A., Groen, A. K., Schwartz, Thue W., Nieuwdorp, M., Bäckhed, F. & Nielsen, J., 2023, In: PLoS ONE. 18, 3, 26 p., e0279335.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Published

      Seven transmembrane G protein-coupled receptor repertoire of gastric ghrelin cells

      Engelstoft, M. S., Park, W-M., Sakata, I., Kristensen, L. V., Husted, A. S., Osborne-Lawrence, S., Piper, P. K., Walker, A. K., Pedersen, M. H., Nøhr, M. K., Pan, J., Sinz, C. J., Carrington, P. E., Akiyama, T. E., Jones, R. M., Tang, C., Ahmed, K., Offermanns, S., Egerod, K. L., Zigman, J. M. & 1 others, Schwartz, Thue W., Nov 2013, In: Molecular Metabolism. 2, 4, p. 376-92 17 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      Similar activation of signal transduction pathways by the herpesvirus-encoded chemokine receptors US28 and ORF74

      McLean, K. A., Holst, Peter Johannes, Martini, L., Schwartz, Thue W. & Rosenkilde, Mette, 2004, In: Virology. 325, 2, p. 241-51 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      Single-chain vascular endothelial growth factor variant with antagonist activity

      Boesen, T. P., Soni, B., Schwartz, Thue W. & Halkier, T., 2002, In: Journal of Biological Chemistry. 277, 43, p. 40335-41 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      Split-receptors in the tachykinin NK-1 system - mutational analysis of intracellular loop 3

      Nielsen, S. M., Elling, C. E. & Schwartz, Thue W., 1998, In: European Journal of Biochemistry. 251, p. 217-226

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      Steric hindrance mutagenesis versus alanine scan in mapping of ligand binding sites in the tachykinin NK1 receptor

      Holst, Birgitte, Jensen, S. Z., Elling, C. E., Hjorth, S. A. & Schwartz, Thue W., 1998, In: Molecular Pharmacology. 53, no. 1, p. 166-175

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Structural basis for GPCR signaling by small polar versus large lipid metabolites-discovery of non-metabolite ligands

      Lückmann, Michael, Trauelsen, Mette, Frimurer, Thomas Michael & Schwartz, Thue W., 2020, In: Current Opinion in Cell Biology. 63, p. 38-48

      Research output: Contribution to journal › Review › Research › peer-review

    9. Published

      Structural basis for constitutive activity and agonist-induced activation of the enteroendocrine fat sensor GPR119

      Engelstoft, M. S., Norn, C., Pedersen, M. H., Holliday, N. D., Elster, L., Lehmann, J., Jones, R. M., Frimurer, Thomas Michael & Schwartz, Thue W., Dec 2014, In: British Journal of Pharmacology. 171, 24, p. 5774-89 16 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Structural biology: A moving story of receptors

      Schwartz, Thue W. & Hubbell, W. L., 2008, In: Nature. 455, 7212, p. 473-4 1 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Structural biology: Full monty of family B GPCRs

      Schwartz, Thue W. & Frimurer, Thomas Michael, 2017, In: Nature Chemical Biology. 13, 8, p. 819-821

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Structural biology: snapshot of a signalling complex.

      Schwartz, Thue W. & Sakmar, T., Sep 2011, In: Nature.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      Structure-Activity Investigations and Optimisations of Non-metabolite Agonists for the Succinate Receptor 1

      Ulven, Elisabeth Rexen, Trauelsen, Mette, Brvar, M., Lückmann, Michael, Bielefeldt, L. Ø., Jensen, L. K. I., Schwartz, Thue W. & Frimurer, Thomas Michael, 2018, In: Scientific Reports. 8, 1, p. 1-18 10010.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      Structure-based discovery of novel US28 small molecule ligands with different modes of action

      Lückmann, Michael, Amarandi, R., Papargyri, N., Jakobsen, M. H., Ulven, Elisabeth Rexen, Jensen, Lars Juhl, Pui, A., Schwartz, Thue W., Rosenkilde, Mette & Frimurer, Thomas Michael, 2017, In: Chemical Biology & Drug Design. 89, 3, p. 289–296

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      Studies of relationships between variation of the human G protein-coupled receptor 40 Gene and Type 2 diabetes and insulin release

      Hamid, Y. H., Vissing, H., Holst, Birgitte, Urhammer, S. A., Pyke, C., Hansen, S. K., Glümer, C., Borch-Johnsen, K., Jørgensen, T., Schwartz, Thue W., Pedersen, O. & Hansen, Torben, 2005, In: Diabetic Medicine. 22, 1, p. 74-80 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Synthetic G protein-coupled bile acid receptor agonists and bile acids act via basolateral receptors in ileal and colonic mucosa

      Tough, I. R., Schwartz, Thue W. & Cox, H. M., 2020, In: Neurogastroenterology and Motility. 32, 12, 14 p., e13943.

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      Targeting CXCR4 in HIV Cell-Entry Inhibition

      Steen, A., Schwartz, Thue W. & Rosenkilde, Mette, 2010, In: Mini reviews in medicinal chemistry. 9, 14, p. 1605-21 16 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      The CCR5 receptor acts as an alloantigen in CCR5¿32 homozygous individuals: Identification of chemokine- and HIV-1 blocking human antibodies

      Ditzel, H. J., Rosenkilde, Mette, Garred, P., Wang, M., Pedersen, C., Burton, D. R. & Schwartz, Thue W., 1998, In: Proceedings of the National Academy of Science of the United States of America. 95, no. 9, p. 5241-5245

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      The CXC chemokine receptor encoded by herpesvirus saimiri, ECRF3, shows ligand-regulated signaling through Gi, Gq, and G12/13 proteins but constitutive signaling only through Gi and G12/13 proteins

      Rosenkilde, Mette, McLean, K. A., Holst, Peter Johannes & Schwartz, Thue W., 2004, In: Journal of Biological Chemistry. 279, 31, p. 32524-33 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      The HETE Is on FFAR1 and Pancreatic Islet Cells

      Trauelsen, Mette, Lückmann, Michael, Frimurer, Thomas Michael & Schwartz, Thue W., 2018, In: Cell Metabolism. 27, 2, p. 273-275 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      The MicroRNA Repertoire in Enteroendocrine Cells: Identification of miR-375 as a Potential Regulator of the Enteroendocrine Lineage

      Knudsen, L. A., Petersen, N., Schwartz, Thue W. & Egerod, Kristoffer Lihme, Nov 2015, In: Endocrinology. 156, 11, p. 3971-83 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      The Molecular Diversity of Vagal Afferents Revealed

      Egerod, Kristoffer Lihme, Schwartz, Thue W. & Gautron, L., 2019, In: Trends in Neurosciences. 42, 10, p. 663-666

      Research output: Contribution to journal › Editorial › Research › peer-review

    23. Published

      The PP-fold solution structure of human polypeptide YY and human PYY3-36 as determined by NMR

      Nygaard, R., Nielbo, S., Schwartz, Thue W. & Poulsen, F. M., 2006, In: Biochemistry. 45, 27, p. 8350-7 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      The adhesion G protein-coupled receptor G2 (ADGRG2/GPR64) constitutively activates SRE and NFκB and is involved in cell adhesion and migration

      Cornelia Peeters, M., Fokkelman, M., Boogaard, B., Egerod, Kristoffer Lihme, van de Water, B., IJzerman, A. P. & Schwartz, Thue W., Dec 2015, In: Cellular Signalling. 27, 12, p. 2579-88 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      The arginine of the DRY motif in transmembrane segment III functions as a balancing micro-switch in the activation of the β2-adrenergic receptor

      Hansen, L. V., Groenen, M., Nygaard, R., Frimurer, Thomas Michael, Holliday, N. D. & Schwartz, Thue W., 14 Sep 2012, In: Journal of Biological Chemistry. 287, 38, p. 31973-82 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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