Jens Juul Holst

Jens Juul Holst

Professor


  1. 2000
  2. Published

    Degradation of endogenous and exogenous gastric inhibitory polypeptide in healthy and in type 2 diabetic subjects as revealed using a new assay for the intact peptide

    Deacon, Carolyn F., Nauck, M. A., Meier, J., Hücking, K. & Holst, Jens Juul, 2000, In: Journal of Clinical Endocrinology and Metabolism. 85, p. 3575-3581

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    PACAP contributes to insulin secretion after gastric glucose gavage in mice

    Filipsson, K., Holst, Jens Juul & Ahrén, B., 2000, In: Am. J. Physiol.. 279, p. R424-432

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    The effect of glucagon-like peptide-1 on energy expenditure and substrate metabolism in humans

    Flint, A., Raben, A., Rehfeld, J. F., Holst, Jens Juul & Astrup, A., 2000, In: International Journal of Obesity. 24, p. 288-298

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Somastostatin restrains the secretion of glucagon-like peptide-1 and 2 (GLP-1 and GLP-2) from isolated perfused porcine ileum

    Hansen, L., Hartmann, B., Bisgaard, T., Mineo, H., Jørgensen, P. N. & Holst, Jens Juul, 2000, In: Am. J. Physiol.. 278, p. E1010-E1018

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Dipeptidyl peptidase IV inhibition enhances the intestinotrophic effect of glucagon-like peptide-2 in rats and mice

    Hartmann, Bolette, Thulesen, J., Kissow, Hannelouise, Thulesen, S., Ørskov, Cathrine, Ropke, C., Poulsen, Steen Seier & Holst, Jens Juul, 2000, In: Endocrinology. 141, 11, p. 4013-20 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    In vivo and in vitro degradation of glucagon-like peptide-2 in humans

    Hartmann, B., Harr, M. B., Jeppesen, P. B., Wojdemann, M., Deacon, Carolyn F., Mortensen, P. B. & Holst, Jens Juul, 2000, In: Journal of Clinical Endocrinology and Metabolism. 85, p. 2884-2888

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Effect of glucagon-like peptide 1 (7-356) amide in insulin treated patients with diabetes mellitus secondary to chronic pancreatitis

    Hedetoft, C., Larsen, S., Sheikh, S. & Holst, Jens Juul, 2000, In: Pancreas. 20, p. 25-31

    Research output: Contribution to journalJournal articleResearch

  9. Published

    Glucose mediated glucose disposal in insulin resistant normoglycemic relatives of type 2 diabetic patients

    Henriksen, J. E., Levin, K., Thye-Rønn, P., Alford, F., Hother-Nielsen, O., Holst, Jens Juul & Beck-Nielsen, H., 2000, In: Diabetes. 49, p. 1209-1218

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Elevated circulating leptin in arterial hypertension: relationship to arteriovenous overflow and extraction of leptin

    Henriksen, J. H., Holst, Jens Juul, Møller, S., Jensen, G. & Bendtsen, Flemming, 2000, In: Clin.Sci.. 99, p. 527-534

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Gut hormones as pharmaceuticals. From enteroglucagon to GLP-1 and GLP-2

    Holst, Jens Juul, 2000, In: Review Regul Pept. 93, p. 45-51

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Regulatory peptides of the gastrointestinal tract

    Holst, Jens Juul, 2000, Small Bowel Disorders. London: Small Bowel Disorders, p. 96-115

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  13. Published

    Elevated plasma glucagon-like peptide 1 and 2 concentrations in ileum resected short bowel patients with a preserved colon

    Jeppesen, Palle Bekker, Hartmann, Bolette, Thulesen, J., Hansen, B. S., Holst, Jens Juul, Poulsen, Steen Seier & Mortensen, P. B., Sep 2000, In: Gut. 47, 3, p. 370-6 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Elevated fasting glucagon-like peptide 1 and 2 secretion in ileum-resected short bowel patients with a preserved colon

    Jeppesen, P. B., Hartmann, B., Hansen, B. S., Poulsen, Steen Seier, Thulesen, J., Holst, Jens Juul & Mortensen, P. B., 2000, In: Gut. 47, p. 370-376

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Short-term treatment with GLP-1 increases pulsatile secretion in type 2 diabetes with no effect on orderliness.

    Juhl, C. B., Schmitz, O., Holst, Jens Juul, Vedhuis, J. & Pørksen, N., 2000, In: Diabetologia. 43, p. 583-588

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Influence of acarbose on postprandial insulin requirements in patients with type 1 diabetes

    Juntti-Berggren, L., Pigon, J., Hellström, P. M., Holst, Jens Juul & Efendic, S., 2000, In: Diab Nutr Metab. 13, p. 7-12

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Circulating levels of incretin hormones an amylin in the fasting state and after oral glucose in growth hormone (GH-)deficient patients before and after GH replacement. A placebo controlled study

    Jørgensen, J. O. L., Rosenfalck, A. M., Fisker, S., Nyholm, B., Fineman, M. S., Schmitz, O., Madsbad, S., Holst, Jens Juul & Christiansen, J. S., 2000, In: European Journal of Endocrinology. 143, p. 593-599

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Effects of oral glucose on systemic glucose metabolism during hyperinsulinaemic hypoglycemia in normal man

    Poulsen, P. L., Grøfte, T., Holck, P., Møller, J., Schmitz, O., Ørskov, L., Holst, Jens Juul & Møller, N., 2000, In: Metabolism. 49, p. 1598-1603

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Deficiency of the intestinal growth factor, glucagon-like peptide 2, in the colon of SCID mice with inflammatory bowel disease induced by transplantation of CD4+ T cells

    Schmidt, P. T., Hartmann, Bolette, Bregenholt, S., Holst, Jens Juul & Claesson, Mogens Helweg, 1 May 2000, In: Scandinavian Journal of Gastroenterology. 35, 5, p. 522-7 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Tachykinins in the porcine pancreas: potent exocrine and endocrine effects via NK-1 receptors

    Schmidt, P. T., Tornøe, K., Poulsen, Steen Seier, Rasmussen, T. N. & Holst, Jens Juul, Apr 2000, In: Pancreas. 20, 3, p. 241-7 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Tachykinins in the porcine pancreas: potent exocrine and endocrine effects via NK-1 receptors

    Schmidt, P. T., Tornøe, K., Poulsen, Steen Seier, Nygaard, T. & Holst, Jens Juul, 2000, In: Pancreas. 20, p. 241-247

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Tachykinins in the regulation of gastric motility and secretion

    Schmidt, P. T. & Holst, Jens Juul, 2000, In: Review Cellular and Molecular Life Sciences. 57, p. 579-588

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Potential targets for glucagon-like peptide 2 (GLP-2) in the rat: distribution and binding of i.v. injected (125)I-GLP-2

    Thulesen, J., Hartmann, Bolette, Ørskov, Cathrine, Jeppesen, Palle Bekker, Holst, Jens Juul & Poulsen, Steen Seier, Oct 2000, In: Peptides. 21, 10, p. 1511-7 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Potential targets for glucagon-like peptide 2 (GLP-2) in the rat: distribution and binding of i.v. injected (125)I-GLP-2

    Thulesen, J., Hartmann, B., Ørskov, Cathrine, Jeppesen, P. B., Holst, Jens Juul & Poulsen, Steen Seier, 2000, In: Peptides. 10, p. 1511-1517

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    PACAP 1-38 as neurotransmitter in porcine adrenal glands

    Tornøe, K., Hannibal, J., Rickelt, L. F., Bolding Jensen, M., Børglum, J. T., Fahrenkrug, J. & Holst, Jens Juul, 2000, In: American Journal of Physiology: Endocrinology and Metabolism. 279, p. E1412-E1425

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Effect of glucagon-like peptide-1-(7,36)-amide on glucose effectiveness and insulin action in people with type 2 diabetes mellitus

    Vella, A., Shah, P., Basu, R., Basu, A., Holst, Jens Juul & Rizza, R. A., 2000, In: Diabetes. 49, p. 611-617

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Evaluation of ß-cell secretory capacity using glucagon-like peptide-1

    Visbøll, T., Toft-Nielsen, M., Krarup, T., Madsbad, S., Dinesen, B. & Holst, Jens Juul, 2000, In: Diabetes Care. 23, p. 807-812

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Neurogenic nitric oxide and exocrine secretion in the gastrointestinal tract

    Ørskov, Cathrine & Holst, Jens Juul, 2000, Nitric Oxide and the Peripheral Nervous System. London, UK: Portland Press Ltd., p. 131

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  29. 1999
  30. Published

    Inhibition of dipeptidyl peptidase IV with NVP DPP728 increases plasma GLP-1 (7-36amide) concentrations and improves oral glucose tolerance in obese Zucker rats

    Balkan, B., Kwasnik, L., Miserendino, R., Holst, Jens Juul & Lie, X., 1999, In: Diabetologia. 42, p. 1324-1331

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Selectivity of prandial glucose regulators: nateglinide, but not repaglinide, accelerates exocytosis in rat pancreatic A-cells

    Bokvist, K., Høy, M., Buschard, K., Holst, Jens Juul, Thomsen, M. K. & Gromada, J. L., 1999, In: Eur. J. Pharmacol.. 386, p. 105-111

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Proglucagon processing profile in canine L cells expressing endogenous prohormone convertase 1/3 and prohormone convertase 2

    Damholt, A. B., Buchan, A. M., Holst, Jens Juul & Kofod, H., Oct 1999, In: Endocrinology. 140, 10, p. 4800-8 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Proglucagon cleavage profile in canine L-cells expressing endogenous PC-1/3 and PC-2

    Damholt, A. B., Buchan, A. M. J., Holst, Jens Juul & Kofod, H., 1999, In: Endokrinologiya. 140, p. 4800-4808

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Glucagon-like peptide-1: a basis for new approaches to the management of diabetes

    Deacon, Carolyn F., Holst, Jens Juul & Carr, R. D., Mar 1999, In: Drugs of Today. 35, 3, p. 159-70 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Glucagon-like peptide-1: A basis for new approaches to the management of Diabetes

    Deacon, Carolyn F., Holst, Jens Juul & Carr, R. D., 1999, In: Drugs of Today. 35, p. 159-170

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Glucagon-like peptide-1 suppresses energy expenditure in obese humans

    Flint, A., Raben, A., Holst, Jens Juul & Astrup, A., 1999, International journal of obesity. Després, J-P. & Macdonald, I. (eds.). 23 ed. European Association for the Study of Obesity, p. S35 1 p.

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearch

  37. Published

    Glucagon-like peptide-1-(7-36)amide is transformed to glucagon-like peptide-1-(9-36)amide by dipeptidyl peptidase IV in the capillaries supplying the L cells of the porcine intestine

    Hansen, L., Deacon, Carolyn F., Ørskov, Cathrine & Holst, Jens Juul, Nov 1999, In: Molecular Endocrinology. 140, 11, p. 5356-63 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Glucagon-like peptide-1(7-36)amide is transformed to glucagon-like peptide-1 (9-36)amide by dipeptidyl peptidase IV in the capillaries supplying the intestinal L-cells

    Hansen, L., Deacon, Carolyn F., Ørskov, C. & Holst, Jens Juul, 1999, In: Endokrinologiya. 140, p. 5356-5363

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Increased Circulating leptin in cirrhosis: relation to release and disposal

    Henriksen, J. H., Holst, Jens Juul, Møller, S., Brinch, K. & Bendtsen, Flemming, 1999, In: Hepatology. 29, p. 1818-1824

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Glucagon-like peptide-1 (GLP-1): An intestinal hormone, signalling nutritional abundance, with an unusual therapeutic potential

    Holst, Jens Juul, 1999, In: Trends in Endocrinology and Metabolism. 10, p. 229-235

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Glucagon-like peptide-1, a gastrointestinal hormone with a pharmaceutical potential

    Holst, Jens Juul, 1999, In: Current Medicinal Chemistry. 6, p. 1005-1017

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Treatment of Type 2 diabetes mellitus based on glucagon-like peptide-1

    Holst, Jens Juul, 1999, In: Exp. Opin. Invest. Drugs. 8, p. 1409-1415

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Treatment of Type 2 diabetes mellitus based on glucagon-like peptide-1

    Holst, Jens Juul, Sep 1999, In: Expert Opinion on Investigational Drugs. 8, 9, p. 1409-15 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    The hypothalamic satiety peptide CART is expressed in anorectic and non-anorectic pancreatic islet tumors and in the normal islet of Langerhans

    Jensen, P. B., Kristensen, P., Clausen, J. T., Judge, M. E., Hastrup, S., Thim, L., Wulff, B. S., Foged, C., Jensen, J., Holst, Jens Juul & Madsen, O. D., 1999, In: FEBS Letters. 447, p. 139-143

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Impaired meal-stimulated glucagon-like peptide-2 responses in short bowel patients with intestinal failure

    Jeppesen, P. B., Hansen, B. S., Hartmann, B., Holst, Jens Juul & Mortensen, P. B., 1999, In: Gut. 45, p. 559-563

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Increased intensity of physical activity stimulates subsequent fat intake

    Klausen, B., Toubro, S., Ranneries, C., Rehfeld, J. F., Holst, Jens Juul, Christensen, N. J. & Astrup, A., 1999, In: International Journal of Obesity. 23, p. 1282-1287

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Advances in non-peptide glucagon receptor antagonist

    Madsen, P., Knudsen, L. B., Brand, C. L. & Holst, Jens Juul, 1999, In: Curr. Pharm Design. 5, p. 683-691

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Hour profiles of insulin, subtrates and gut incretin hormones: Early defects in glucose tolerant offspring of type II (non-insulin dependent) diabetic paitents

    Nyholm, B., Walker, M. J. C., Gravholdt, C. H., Alberti, K. G. M. M., Holst, Jens Juul & Schmitz, O., 1999, In: Diabetologia. 42, p. 1314-1323

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Energy intake and appetite is suppressed by glucagon-like peptide-1 (GLP-1) in obese men

    Näslund, E., Barkeling, B., King, N., Gutniak, M. K., Blundell, J. E., Holst, Jens Juul, Rössner, S. & Hellström, P. M., 1999, In: International Journal of Obesity. 23, p. 304-311

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Glucagon-like peptide-1 slows solid gastric emptying and inhibits insulin, glucagon and peptide YY release in humans

    Näslund, E., Bogefors, J., Skogar, S., Grybäck, P., Jacobsen, H. L., Holst, Jens Juul & Helström, P. M., 1999, In: Am. J. Physiol.. 277, p. 910-916

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Importance of colonic fermentation in short bowel patients. Small intestinal malabsorption of easily digestible carbohydrate

    Olesen, M., Gudmand-Høyer, E., Holst, Jens Juul & Jørgensen, S., 1999, In: Dig. Dis. Sci.. 44, p. 1914-1923

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Octreotide suppresses the incretin GLP-1 in patients with acromegally, clinically nonfunctioning pituitary tumours and in healthy subjects

    Plöckinger, U., Holst, Jens Juul, Messerschmidt, D., Hopfenmüller, W. & Quabbe, H. J., 1999, In: European Journal of Endocrinology. 140, p. 538-544

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 4207