Thue W. Schwartz
Professor
Schwartz Group
Blegdamsvej 3B, Mærsk Tårnet, 6. sal, 2200 København N.
Member of:
- Published
A highly selective CCR2 chemokine agonist encoded by human herpesvirus 6
Lüttichau, H. R., Clark-Lewis, I., Jensen, Peter Østrup, Moser, C., Gerstoft, Jan & Schwartz, Thue W., 2003, In: Journal of Biological Chemistry. 278, Vol. 278 (13), p. 10928-33 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The herpesvirus 8-encoded chemokine vMIP-II, but not the poxvirus-encoded chemokine MC148, inhibits the CCR10 receptor
Lüttichau, H. R., Lewis, I. C., Gerstoft, Jan & Schwartz, Thue W., 2001, In: European Journal of Immunology. 31, 4, p. 1217-20 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
MC148 encoded by human molluscum contagiosum poxvirus is an antagonist for human but not murine CCR8
Lüttichau, H. R., Gerstoft, Jan & Schwartz, Thue W., 2001, In: Journal of Leukocyte Biology. 70, 2, p. 277-82 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In Silico Investigation of the Neurotensin Receptor 1 Binding Site: Overlapping Binding Modes for Small Molecule Antagonists and the Endogenous Peptide Agonist
Lückmann, Michael, Holst, Birgitte, Schwartz, Thue W. & Frimurer, Thomas Michael, 2016, In: Molecular Informatics. 35, p. 19-24 6 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Optimization of First-in-Class Dual-Acting FFAR1/FFAR4 Allosteric Modulators with Novel Mode of Action
Lückmann, Michael, Iliyaz, Aslihan Shenol, Nissen, T. A. D., Petersen, Jacob Emil, Kouvchinov, David, Schwartz, Thue W. & Frimurer, Thomas Michael, 2022, In: ACS Medicinal Chemistry Letters. 13, 12, p. 1839-1847Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular dynamics-guided discovery of an ago-allosteric modulator for GPR40/FFAR1
Lückmann, Michael, Trauelsen, Mette, Bentsen, M. A., Nissen, T. A. D., Martins, J., Fallah, Z., Nygaard, M. M., Papaleo, E., Lindorff-Larsen, Kresten, Schwartz, Thue W. & Frimurer, Thomas Michael, 2 Apr 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 14, p. 7123-7128Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structure-based discovery of novel US28 small molecule ligands with different modes of action
Lückmann, Michael, Amarandi, R., Papargyri, N., Jakobsen, M. H., Ulven, Elisabeth Rexen, Jensen, Lars Juhl, Pui, A., Schwartz, Thue W., Rosenkilde, Mette & Frimurer, Thomas Michael, 2017, In: Chemical Biology & Drug Design. 89, 3, p. 289–296Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lactate receptor GPR81 drives breast cancer growth and invasiveness through regulation of ECM properties and Notch ligand DLL4
Jørgensen, Kathrine Lundø, Dmytriyeva, O., Spøhr, L., Alves, Eliana Carolina Goncalves, Yao, Jiayi, Puig Blasco, Laia, Trauelsen, Mette, Ponniah, M., Severin, M., Sandelin, Albin Gustav, Kveiborg, Marie, Schwartz, Thue W. & Pedersen, Stine Helene Falsig, 2023, In: BMC Cancer. 23, 1, 20 p., 1136.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
L-cell Differentiation Is Induced by Bile Acids Through GPBAR1 and Paracrine GLP-1 and Serotonin Signaling
Lund, M. L., Sorrentino, G., Egerod, Kristoffer Lihme, Kroone, C., Mortensen, B., Knop, Filip Krag, Reimann, F., Gribble, F. M., Drucker, D. J., De Koning, E. J. P., Schoonjans, K., Bäckhed, F., Schwartz, Thue W. & Petersen, N., Apr 2020, In: Diabetes. 69, 4, p. 614-623 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Enterochromaffin 5-HT cells - A major target for GLP-1 and gut microbial metabolites
Lund, M. L., Egerod, Kristoffer Lihme, Engelstoft, M. S., Dmytriyeva, O., Theodorsson, E., Patel, B. A. & Schwartz, Thue W., 2018, In: Molecular Metabolism. 11, p. 70-83 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Outrunning obesity with Lac-Phe?
Lund, Jens, Clemmensen, Christoffer & Schwartz, Thue W., 2022, In: Cell Metabolism. 34, 8, p. 1085-1087 3 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Structural basis for GPCR signaling by small polar versus large lipid metabolites-discovery of non-metabolite ligands
Lückmann, Michael, Trauelsen, Mette, Frimurer, Thomas Michael & Schwartz, Thue W., 2020, In: Current Opinion in Cell Biology. 63, p. 38-48Research output: Contribution to journal › Review › Research › peer-review
- Published
The virus-encoded chemokine vMIP-II inhibits virus-induced Tc1-driven inflammation
Lindow, M., Nansen, A., Bartholdy, C., Stryhn, A., Hansen, N. J. V., Boesen, T. P., Wells, T. N. C., Schwartz, Thue W. & Thomsen, Allan Randrup, 2003, In: Journal of Virology. 77, 13, p. 7393-400 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Viral leads for chemokine-modulatory drugs
Lindow, M., Lüttichau, H. R. & Schwartz, Thue W., 2003, In: TIPS - Trends in Pharmacological Sciences. 24, 3, p. 126-30 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Resequencing of 200 human exomes identifies an excess of low-frequency non-synonymous coding variants
Li, Y., Vinckenbosch, N., Tian, G., Huerta-Sanchez, E., Jiang, T., Jiang, H., Albrechtsen, A., Andersen, G., Cao, H., Korneliussen, T. S., Grarup, N., Guo, Y., Hellman, I., Jin, X., Li, Q., Liu, J., Liu, X., Sparsø, T., Tang, M., Wu, H. & 18 others, , 2010, In: Nature Genetics. 42, 11, p. 969-72 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Binding of norbinaltorphimine (norBNI) congeners to wild-type and mutant mu and kappa opioid receptors: molecular recognition loci for the pharmacophore and address components of kappa antagonists
Larson, D. L., Jones, R. M., Hjorth, S. A., Schwartz, Thue W. & Portoghese, P. S., 2000, In: Journal of Medicinal Chemistry. 43, no. 8, p. 1573-6Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Regional distribution of putative NPY Y*U1 receptors and neurons expressing Y*U1 mRNA in forebrain areas of the rat central nervous system
Larsen, P. J., Sheikh, S. P., Jakobsen, C. R., Schwartz, Thue W. & Mikkelsen, J. D., 1993, In: European Journal of Neuroscience. Vol 5, p. 1622-37Research output: Contribution to journal › Journal article › Research › peer-review
- Published
- Published
Self-organized metabotyping of obese individuals identifies clusters responding differently to bariatric surgery
Lappa, D., Meijnikman, A. S., Krautkramer, K. A., Olsson, L. M., Aydin, Ö., Van Rijswijk, A. S., Acherman, Y. I. Z., De Brauw, M. L., Tremaroli, V., Olofsson, L. E., Lundqvist, A., Hjorth, Siv Annegrethe, Ji, B., Gerdes, V. E. A., Groen, A. K., Schwartz, Thue W., Nieuwdorp, M., Bäckhed, F. & Nielsen, J., 2023, In: PLoS ONE. 18, 3, 26 p., e0279335.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Receptorji s sedmimi transmembranskimi območji (7TM) v luči dimerizacije ter eksperimentalni pristopi za proučevanje njihove dimerizacije in medsebojnih vplivov
Kubale, V., Pogačnik, A., Schwartz, Thue W. & Vrecl, M., 2008, In: Slovenian Veterinary Research. 45, 3, p. 89-102 14 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
The MicroRNA Repertoire in Enteroendocrine Cells: Identification of miR-375 as a Potential Regulator of the Enteroendocrine Lineage
Knudsen, L. A., Petersen, N., Schwartz, Thue W. & Egerod, Kristoffer Lihme, Nov 2015, In: Endocrinology. 156, 11, p. 3971-83 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A broadspectrum chemokine antagonist encoded by Karposis sarcoma associated herpes virus
Kledal, T. N., Rosenkilde, Mette, Coulin, F., Simmons, G., Johnsen, A. H., Alouani, S., Schwartz, Thue W., Poucer, C. A., Lüttichau, H. R., Gerstoft, J., Clapham, P. R., Clark-Lewis, I. & Wells, T. N. C., 1997, In: Kexue (Shanghai). 277, p. 1656-1659Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Selective recognition of the membrane-bound CXC3 chemokine, fractal by the human cytomegalovirus-encoded broad-spectrum receptor US28
Kledal, T. N., Rosenkilde, Mette & Schwartz, Thue W., 1998, In: FEBS Letters. 441, p. 209-214Research output: Contribution to journal › Journal article › Research › peer-review
- Published
CD4-chemokine receptor hybrids in human immunodeficiency virus type 1 infection
Klasse, P. J., Rosenkilde, Mette, Signoret, N., Pelchen-Matthews, A., Schwartz, Thue W. & Marsh, M., 1999, In: Journal of Virology. 73, no. 9, p. 7453-7466Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of glucagon-like peptide-1 receptor beta-arrestin 2 interaction: a high-affinity receptor phenotype
Jorgensen, R., Martini, L., Schwartz, Thue W. & Elling, C. E., 2005, In: Molecular Endocrinology. 19, 3, p. 812-23 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 11601
Most downloads
-
4537
downloads
Family and population-based studies of variation within the ghrelin receptor locus in relation to measures of obesity
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
2791
downloads
PDZ domain-mediated interactions of G protein-coupled receptors with postsynaptic density protein 95: quantitative characterization of interactions
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
612
downloads
Receptor structure-based discovery of non-metabolite agonists for the succinate receptor GPR91
Research output: Contribution to journal › Journal article › Research › peer-review
Published