Jens Juul Holst
Professor
Endocrinology and Metabolism
Blegdamsvej 3
2200 København N.
- 2007
- Published
Disassociation of bone resorption and formation by GLP-2: a 14-day study in healthy postmenopausal women
Henriksen, D. B., Alexandersen, P., Hartmann, Bolette, Adrian, C. L., Byrjalsen, I., Bone, H. G., Holst, Jens Juul & Christiansen, C., Mar 2007, In: Bone. 40, 3, p. 723-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gastric emptying of glucose solution and associated plasma concentrations of GLP-1, GIP, and PYY before and after fundoplication
Miholic, J., Hoffmann, M., Holst, Jens Juul, Lenglinger, J., Mittlböck, M., Bergmann, H. & Stacher, G., Feb 2007, In: Surgical Endoscopy. 21, 2, p. 309-14 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Preserved GLP-1 effects in a diabetic patient with Cushing's disease
Ritzel, R. A., Kleine, N., Holst, Jens Juul, Willms, B., Schmiegel, W. & Nauck, M. A., Feb 2007, In: Experimental and Clinical Endocrinology and Diabetes. 115, 2, p. 146-50 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Small-molecule agonists for the glucagon-like peptide 1 receptor
Knudsen, L. B., Kiel, D., Teng, M., Behrens, C., Bhumralkar, D., Kodra, J. T., Holst, J. J., Jeppesen, C. B., Johnson, M. D., de Jong, J. C., Jorgensen, A. S., Kercher, T., Kostrowicki, J., Madsen, P., Olesen, P. H., Petersen, J. S., Poulsen, F., Sidelmann, U. G., Sturis, J., Truesdale, L. & 2 others, , 16 Jan 2007, In: Proceedings of the National Academy of Sciences of the United States of America. 104, 3, p. 937-42 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The antagonistic metabolite of GLP-1, GLP-1 (9-36)amide, does not influence gastric emptying and hunger sensations in man
Nagell, C. F., Pedersen, J. F. & Holst, Jens Juul, Jan 2007, In: Scandinavian Journal of Gastroenterology. 42, 1, p. 28-33 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Acute effects of ghrelin administration on glucose and lipid metabolism.
Vestergaard, E. T., Djurhuus, C. B., Gjedsted, J., Nielsen, S., Møller, N., Holst, Jens Juul, Jørgensen, J. O. L. & Schmitz, O., 2007, In: Journal of Clinical Endocrinology and Metabolism. 93, 2, p. 438-444 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bone resorption is decreased postprandially by intestinal factors and glucagon-like peptide-2 is a possible candidate
Holst, Jens Juul, Hartmann, B., Gottschalck, I. B., Jeppesen, P. B., Miholic, J. & Henriksen, D. B., 2007, In: Scandinavian Journal of Gastroenterology. 42, 7, p. 814-820 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cecal infusion of butyrate increases intestinal cell proliferation in piglets
Kien, C. L., Blauwiekel, R., Bunn, J. Y., Jetton, T. L., Frankel, W. L. & Holst, Jens Juul, 2007, In: Journal of Nutrition. 137, 4, p. 916-922 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Co-localisation of the Kir6.2/SUR1 channel complex with glucagon-like peptide-1 and glucose-dependent insulinotrophic polypeptide expression in human ileal cells and implications for glycaemic control in new onset type 1 diabetes
Nielsen, L. B., Ploug, K. B., Swift, P., Ørskov, A. C., Jansen-Olesen, I., Chiarelli, F., Holst, J. J., Hougaard, P. P., Porksen, S., Holl, R., Beaufort, C. D., Gammeltoft, S., Rorsman, P., Mortensen, H. B., Hansen, L., Nielsen, L. B., Ploug, K. B., Swift, P., Ørskov, C., Jansen-Olesen, I. & 11 others, , 2007, In: European Journal of Endocrinology. 156, 6, p. 663-71 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Disassociation of bone resorption and formation by GLP-2 - A 14-day study in healthy postmenopausal women
Henriksen, D. B., Alexandersen, P., Hartmann, B., Adrian, C. L., Byrjalsen, I., Bone, H. G., Holst, Jens Juul & Christiansen, C., 2007, In: Bone. 40, 3, p. 723-729 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of dairy calcium or supplementary calcium on postprandial fat metabolism, appetite, and subsequent energy intake
Lorenzen, J. K., Nielsen, S., Holst, Jens Juul, Tetens, Inge , Rehfeld, Jens Frederik & Astrup, A., 2007, In: American Journal of Clinical Nutrition. 85, 3, p. 678-687 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of subcutaneous injections of PYY1-36 and PYY3-36 on appetite, ad libitum energy intake, and plasma free fatty acids concentration in obese males
Sloth, B., Davidsen, L., Holst, Jens Juul, Flint, A. & Astrup, A., 2007, In: American Journal of Physiology: Endocrinology and Metabolism. 293, 2, p. E604-E609Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Enteric neural pathways mediate the anti-inflammatory actions of glucagon-like peptide 2
Sigalet, D. L., Wallace, L. E., Holst, Jens Juul, Martin, G. R., Kaji, T., Tanaka, H. & Sharkey, K. A., 2007, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 293, 1, p. G211-G221Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exaggerated glucagon-like peptide-1 and blunted glucose-dependent insulinotropic peptide secretion are associated with Roux-en-Y gastric bypass but not adjustable gastric banding.
Korner, J., Bessler, M., Inabnet, W., Taveras, C. & Holst, Jens Juul, 2007, In: Surgery for Obesity and Related Diseases. 3, 6, p. 597-601 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exendin-4, but not dipeptidyl peptidase IV inhibition, increases small intestinal mass in GK rats.
Simonsen, L., Pilgaard, S., Orskov, C., Rosenkilde, Mette, Hartmann, B., Holst, Jens Juul & Deacon, Carolyn F., 2007, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 293, 1, p. G288-95Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GIP receptor antagonism reverses obesity, insulin resistance, and associated metabolic disturbances induced in mice by prolonged consumption of high-fat diet
McClean, P. L., Irwin, N., Cassidy, R. S., Holst, Jens Juul, Gault, V. A. & Flatt, P. R., 2007, In: American Journal of Physiology: Endocrinology and Metabolism. 293, 6, p. E1746-E1755Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLUT2 and the incretin receptors are involved in glucose-induced incretin secretion
Cani, P. D., Holst, Jens Juul, Drucker, D. J., Delzenne, N. M., Thorens, B., Burcelin, R. & Knauf, C., 2007, In: Molecular and Cellular Endocrinology. 276, 1-2, p. 18-23 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gastric emptying of glucose solution and associated plasma concentrations of GLP-1, GIP, and PYY before and after fundoplication
Miholic, J., Hoffmann, M., Holst, Jens Juul, Lenglinger, J., Mittlbock, M., Bergmann, H. & Stacher, G., 2007, In: Surgical Endoscopy and Other Interventional Techniques. 21, 2, p. 309-314 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gastrointestinal function and metabolic control after construction of an orthotopic ileal neobladder in bladder cancer.
Thorstenson, A., Jacobsson, H., Onelöv, E., Holst, Jens Juul, Hellström, P. M. & Kinn, A., 2007, In: Scandinavian Journal of Urology and Nephrology. 41, 1, p. 14-9 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide 1 (GLP-1) suppresses ghrelin levels in humans via increased insulin secretion
Hagemann, D., Holst, Jens Juul, Gethmann, A., Banasch, M., Schmidt, W. E. & Meier, J. J., 2007, In: Regulatory Peptides. 143, 1-3, p. 64-68 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide 2 has limited efficacy to increase nutrient absorption in fetal and preterm pigs
Sangild, Per Torp, Malo, C., Schmidt, M., Petersen, Y. M., Elnif, J., Holst, Jens Juul & Bunddington, R. K., 2007, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 293, 6, p. R2179-R2184 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-2 in umbilical cord blood from mature infants
Bodé, S., Hartmann, Bolette, Holst, Jens Juul & Greisen, Gorm, 2007, In: Neonatology. 91, 1, p. 49-53 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-2 in umbilical cord blood from mature infants
Bode, S., Hartmann, B., Holst, Jens Juul & Greisen, Gorm, 2007, In: Neonatology. 91, 1, p. 49-53 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hepatic autoregulation: response of glucose production and gluconeogenesis to increased glycogenolysis
Stæhr, P. A., Hother-Nielsen, O., Beck-Nielsen, H., Roden, M., Stingl, H., Holst, Jens Juul, Jones, P. K., Chandramouli, V. & Landau, B. R., 2007, In: American Journal of Physiology: Endocrinology and Metabolism. 292, 5, p. E1265-E1269Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impaired glucagon-like peptide-1-induced insulin secretion in carriers of transcription factor 7-like 2 (TCF7L2) gene polymorphisms
Schafer, S. A., Tschritter, O., Machicao, F., Thamer, C., Stefan, N., Gallwitz, B., Holst, Jens Juul, Dekker, J. M., t'Hart, L. M., Nijpels, G., Haeften, T. W. V., Haring, H. U. & Fritsche, A., 2007, In: Diabetologia. 50, 12, p. 2443-2450 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Meal-stimulated glucagon release is associated with postprandial blood glucose level and does not interfere with glycemic control in children and adolescents with new-onset type 1 diabetes
Porksen, S., Nielsen, L. B., Kaas, A., Kocova, M., Chiarelli, F., Orskov, C., Holst, Jens Juul, Ploug, K. B., Hougaard, P. P., Hansen, L. & Mortensen, H. B., 2007, In: Journal of Clinical Endocrinology and Metabolism. 92, 8, p. 2910-2916 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Measurements of islet function and glucose metabolism with the dipeptidyl peptidase 4 inhibitor vildagliptin in patients with type 2 diabetes
Azuma, K., Rádiková, Z., Mancino, J., Toledo, F. G. S., Thomas, E., Kangani, C., Dalla Man, C., Cobelli, C., Holst, Jens Juul, Deacon, Carolyn F., He, Y., Ligueros-Saylan, M., Serra, D., Foley, J. E. & Kelley, D. E., 2007, In: Journal of Clinical Endocrinology and Metabolism. 93, 2, p. 459-464 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metabolic effects of amino acid mixtures and whey protein in healthy subjects: studies using glucose-equivalent drinks
Nilsson, M., Holst, Jens Juul & Bjorck, I. M. E., 2007, In: American Journal of Clinical Nutrition. 85, 4, p. 996-1004 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
New horizons in diabetes therapy
Holst, Jens Juul & Deacon, Carolyn F., 2007, In: Immunology, Endocrine and Metabolic Agents in Medicinal Chemistry. 7, 1, p. 49-55 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Normal secretion of the incretin hormones glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 during gestational diabetes mellitus
Cypryk, K., Vilsbøll, Tina, Nadel, I., Smyczynska, J., Holst, Jens Juul & Lewinski, A., 2007, In: Gynecological Endocrinology. 23, 1, p. 58-62 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Patients with neuroglycopenia after gastric bypass surgery have exaggerated incretin and insulin secretory responses to a mixed meal
Goldfine, A. B., Mun, E. C., Devine, E., Bernier, R., Baz-Hecht, M., Jones, D. B., Schneider, B. E., Holst, Jens Juul & Patti, M. E., 2007, In: Journal of Clinical Endocrinology and Metabolism. 92, 12, p. 4678-4685 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pharmacodynamics of vildagliptin in patients with type 2 diabetes during OGTT.
He, Y., Wang, Y., Bullock, J. M., Deacon, Carolyn F., Holst, Jens Juul, Dunning, B. E., Ligueros-Saylan, M. & Foley, J. E., 2007, In: Journal of Clinical Pharmacology. 47, 5, p. 633-41 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pharmacokinetics and pharmacodynamics of vildagliptin in patients with type 2 diabetes mellitus.
He, Y., Serra, D., Wang, Y., Campestrini, J., Riviere, G., Deacon, Carolyn F., Holst, Jens Juul, Schwartz, S., Nielsen, J. C. & Ligueros-Saylan, M., 2007, In: Clinical Pharmacokinetics. 46, 7, p. 577-88 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Porcine glucagon-like peptide-2: structure, signaling, metabolism and effects
Pedersen, N. B., Hjøllund, K. R., Johnsen, A. H., Ørskov, Cathrine, Rosenkilde, Mette, Hartmann, B. & Holst, Jens Juul, 2007, In: Regulatory Peptides. 146, 1-3, p. 310-320 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Preserved GLP-1 effects in a diabetic patient with Cushing's disease
Ritzel, R. A., Kleine, N., Holst, Jens Juul, Willms, B., Schmiegel, W. & Nauck, M. A., 2007, In: Experimental and Clinical Endocrinology and Diabetes. 115, 2, p. 146-150 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reduced incretin effect in type 2 diabetes: cause or consequence of the diabetic state?
Knop, F. K., Vilsbøll, Tina, Højberg, P. V., Larsen, S., Madsbad, Sten, Vølund, A., Holst, Jens Juul & Krarup, T., 2007, In: Diabetes. 56, 8, p. 1951-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reduction of hepatic insulin clearance after oral glucose ingestion is not mediated by glucagon-like peptide 1 or gastric inhibitory polypeptide in humans
Meier, J. J., Holst, Jens Juul, Schmidt, W. E. & Nauck, M. A., 2007, In: American Journal of Physiology: Endocrinology and Metabolism. 293, 3, p. E849-E856Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Small molecule ago-allosteric modulators of the human glucagon-like peptide-1 (hGLP-1) receptor
Teng, M., Johnson, M. D., Thomas, C., Kiel, D., Lakis, J. N., Kercher, T., Aytes, S., Kostrowicki, J., Bhumralkar, D., Truesdale, L., May, J., Sidelman, U., Kodra, J. T., Jørgensen, A. S., Olesen, P. H., Jong, J. C. D., Madsen, P., Behrens, C., Pettersson, I., Knudsen, L. B. & 2 others, , 2007, In: Bioorganic & Medicinal Chemistry Letters. 17, 19, p. 5472-5478 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sulfonylurea compounds uncouple the glucose dependence of the insulinotropic effect of glucagon-like peptide 1.
de Heer, J. & Holst, Jens Juul, 2007, In: Diabetes. 56, 2, p. 438-43 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Suppression of glucagon secretion is lower after oral glucose administration than during intravenous glucose administration in human subjects
Meier, J. J., Deacon, Carolyn F., Schmidt, W. E., Holst, Jens Juul & Nauck, M. A., 2007, In: Diabetologia. 50, 4, p. 806-813 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The dipeptidyl peptidase 4 inhibitor vildagliptin does not accentuate glibenclamide-induced hypoglycemia but reduces glucose-induced glucagon-like peptide 1 and gastric inhibitory polypeptide secretion
Ouaghlidi, A. E., Rehring, E., Holst, Jens Juul, Schweizer, A., Foley, J., Holmes, D. & Nauck, M. A., 2007, In: Journal of Clinical Endocrinology and Metabolism. 92, 11, p. 4165-4171 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The dipeptidyl peptidase IV inhibitor vildagliptin suppresses endogenous glucose production and enhances islet function after single-dose administration in type 2 diabetic patients.
Balas, B., Baig, M. R., Watson, C., Dunning, B. E., Ligueros-Saylan, M., Wang, Y., He, Y., Darland, C., Holst, Jens Juul, Deacon, Carolyn F., Cusi, K., Mari, A., Foley, J. E. & DeFronzo, R. A., 2007, In: Journal of Clinical Endocrinology and Metabolism. 92, 4, p. 1249-55 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The dipeptidyl peptidase-4 inhibitor vildagliptin improves beta-cell function and insulin sensitivity in subjects with impaired fasting glucose
Utzschneider, K. M., Tong, J., Montgomery, B., Udayasankar, J., Gerchman, F., Marcovina, S. M., Watson, C. E., Ligueros-Saylan, M. A., Foley, J. E., Holst, Jens Juul, Deacon, Carolyn F. & Kahn, S. E., 2007, In: Diabetes Care. 31, 1, p. 108-113 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The insulinotropic effect of GIP is impaired in patients with chronic pancreatitis and secondary diabetes mellitus as compared to patients with chronic pancreatitis and normal glucose tolerance.
Knop, F. K., Vilsbøll, Tina, Højberg, P. V., Larsen, S., Madsbad, Sten, Holst, Jens Juul & Krarup, T., 2007, In: Regulatory Peptides. 144, 1-3, p. 123-30 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The intestinotrophic peptide, glp-2, counteracts intestinal atrophy in mice induced by the epidermal growth factor receptor inhibitor, gefitinib.
Hare, K. J., Hartmann, B., Kissow, Hannelouise, Holst, Jens Juul & Poulsen, Steen Seier, 2007, In: Clinical Cancer Research. 13, 17, p. 5170-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The physiology of glucagon-like peptide 1.
Holst, Jens Juul, 2007, In: Physiological Reviews. 87, 4, p. 1409-39 30 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2006
- Published
Glucagon-like peptide 2 inhibits ghrelin secretion in humans
Banasch, M., Bulut, K., Hagemann, D., Schrader, H., Holst, Jens Juul, Schmidt, W. E. & Meier, J. J., 10 Dec 2006, In: Regulatory Peptides. 137, 3, p. 173-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of incretin hormones on beta-cell function in subjects with normal or impaired glucose tolerance
Muscelli, E., Mari, A., Natali, A., Astiarraga, B. D., Camastra, S., Frascerra, S., Holst, Jens Juul & Ferrannini, E., Dec 2006, In: American Journal of Physiology: Endocrinology and Metabolism. 291, 6, p. E1144-50Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Synergistic effect of supplemental enteral nutrients and exogenous glucagon-like peptide 2 on intestinal adaptation in a rat model of short bowel syndrome
Liu, X., Nelson, D. W., Holst, Jens Juul & Ney, D. M., Nov 2006, In: Uden navn. 84, 5, p. 1142-50 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Vagal afferents are essential for maximal resection-induced intestinal adaptive growth in orally fed rats
Nelson, D. W., Liu, X., Holst, Jens Juul, Raybould, H. E. & Ney, D. M., Nov 2006, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 291, 5, p. R1256-64Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Wheat-fibre-induced changes of postprandial peptide YY and ghrelin responses are not associated with acute alterations of satiety
Weickert, M. O., Spranger, J., Holst, Jens Juul, Otto, B., Koebnick, C., Möhlig, M. & Pfeiffer, A. F. H., Nov 2006, In: The British Journal of Nutrition. 96, 5, p. 795-8 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plasma dipeptidyl peptidase-IV activity in patients with type-2 diabetes mellitus correlates positively with HbAlc levels, but is not acutely affected by food intake
Ryskjaer, J., Deacon, Carolyn F., Carr, R. D., Krarup, T., Madsbad, Sten, Holst, Jens Juul, Vilsbøll, Tina, Ryskjaer, J., Deacon, C. F., Carr, R. D., Krarup, T., Madsbad, Sten, Holst, J. J. & Vilsbøll, T., 1 Sep 2006, In: European Journal of Endocrinology. 155, 3, p. 485-93 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ghrelin stimulates gastric emptying and hunger in normal-weight humans
Levin, F., Edholm, T., Schmidt, P. T., Grybäck, P., Jacobsson, H., Degerblad, M., Höybye, C., Holst, Jens Juul, Rehfeld, Jens Frederik, Hellström, P. M. & Näslund, E., Sep 2006, In: The Journal of clinical endocrinology and metabolism. 91, 9, p. 3296-302 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Switching from insulin to oral sulfonylureas in patients with diabetes due to Kir6.2 mutations
Pearson, E. R., Flechtner, I., Njølstad, P. R., Malecki, M. T., Flanagan, S. E., Larkin, B., Ashcroft, F. M., Klimes, I., Codner, E., Iotova, V., Slingerland, A. S., Shield, J., Robert, J., Holst, Jens Juul, Clark, P. M., Ellard, S., Søvik, O., Polak, M., Hattersley, A. T. & Neonatal Diabetes International Collaborative Group, N. D. I. C. G., 3 Aug 2006, In: New England Journal of Medicine. 355, 5, p. 467-77 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The rate of intestinal glucose absorption is correlated with plasma glucose-dependent insulinotropic polypeptide concentrations in healthy men
Wachters-Hagedoorn, R. E., Priebe, M. G., Heimweg, J. A. J., Heiner, A. M., Englyst, K. N., Holst, Jens Juul, Stellaard, F. & Vonk, R. J., Jun 2006, In: Journal of Nutrition. 136, 6, p. 1511-6 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exendin-4, but not glucagon-like peptide-1, is cleared exclusively by glomerular filtration in anaesthetised pigs
Simonsen, L., Holst, Jens Juul & Deacon, Carolyn F., Apr 2006, In: Diabetologia. 49, 4, p. 706-12 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide 1 abolishes the postprandial rise in triglyceride concentrations and lowers levels of non-esterified fatty acids in humans
Meier, J. J., Gethmann, A., Götze, O., Gallwitz, B., Holst, Jens Juul, Schmidt, W. E. & Nauck, M. A., Mar 2006, In: Diabetologia. 49, 3, p. 452-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of a high-protein breakfast on the postprandial ghrelin response
Blom, W. A. M., Lluch, A., Stafleu, A., Vinoy, S., Holst, Jens Juul, Schaafsma, G. & Hendriks, H. F. J., Feb 2006, Effect of a high-protein breakfast on the postprandial ghrelin response. Vol. 83. p. 211-20 10 p. (Uden navn).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Glucagon-like peptide-1: from extract to agent. The Claude Bernard Lecture, 2005
Holst, Jens Juul, Feb 2006, In: Diabetologia. 49, 2, p. 253-60 8 p.Research output: Contribution to journal › Journal article › Communication
- Published
The metabolite generated by dipeptidyl-peptidase 4 metabolism of glucagon-like peptide-1 has no influence on plasma glucose levels in patients with type 2 diabetes
Zander, M., Madsbad, Sten, Deacon, Carolyn F. & Holst, Jens Juul, Feb 2006, In: Diabetologia. 49, 2, p. 369-74 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Feeding an elemental diet vs a milk-based formula does not decrease intestinal mucosal growth in infant pigs
Stoll, B., Price, P. T., Reeds, P. J., Chang, X., Henry, J. F., van Goudoever, J. B., Holst, Jens Juul & Burrin, D. G., 3 Jan 2006, In: Journal of Parenteral and Enteral Nutrition. 30, 1, p. 32-9 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-2 receptor localizes to enteric neurons and endocrine cells expressing vasoactive peptides and mediates increased blood flow
Guan, X., Karpen, H. E., Stephens, J., Bukowski, J. T., Niu, S., Zhang, G., Stoll, B., Finegold, M. J., Holst, Jens Juul, Hadsell, D., Hadsell, D. L., Nichols, B. L. & Burrin, D. G., Jan 2006, In: Gastroenterology. 130, 1, p. 150-64 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide 2 stimulates glucagon secretion, enhances lipid absorption, and inhibits gastric acid secretion in humans
Meier, J. J., Nauck, M. A., Pott, A., Heinze, K., Goetze, O., Bulut, K., Schmidt, W. E., Gallwitz, B. & Holst, Jens Juul, Jan 2006, In: Gastroenterology. 130, 1, p. 44-54 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Diet- and colonization-dependent intestinal dysfunction predisposes to necrotizing enterocolitis in preterm pigs
Sangild, Per Torp, Siggers, R. H., Schmidt, M., Elnif, J., Bjørnvad, Charlotte Reinhard, Thymann, Thomas, Grøndahl, M. L., Hansen, Axel Kornerup, Jensen, S. K., Boye, M., Moelbak, L., Buddington, R. K., Weström, B. R., Holst, Jens Juul & Burrin, D. G., 2006, In: Gastroenterology. 130, 6, p. 1776-1792 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of a high-protein breakfast on the postprandial ghrelin response
Blom, W. A. M., Lluch, A., Stafleu, A., Vinoy, S., Holst, Jens Juul, Schaafsma, G. & Hendriks, H. F. J., 2006, In: American Journal of Clinical Nutrition. 83, 2, p. 211-220 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of single oral doses of sitagliptin, a dipeptidyl peptidase-4 inhibitor, on incretin and plasma glucose levels after an oral glucose tolerance test in patients with type 2 diabetes.
Herman, G. A., Bergman, A., Stevens, C., Kotey, P., Yi, B., Zhao, P., Dietrich, B., Golor, G., Schrodter, A., Keymeulen, B., Lasseter, K. C., Kipnes, M. S., Snyder, K., Hilliard, D., Tanen, M., Cilissen, C., De Smet, M., de Lepeleire, I., Van Dyck, K., Wang, A. Q. & 7 others, , 2006, In: Journal of Clinical Endocrinology and Metabolism. 91, 11, p. 4612-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of PYY1-36 and PYY3-36 on appetite, energy intake, energy expenditure, glucose and fat metabolism in obese and lean subjects.
Sloth, B., Holst, Jens Juul, Flint, A., Gregersen, N. T. & Astrup, A., 2006, In: American Journal of Physiology: Endocrinology and Metabolism. 292, 4, p. E1062-E1068 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of gastric emptying on the postprandial ghrelin response
Blom, W. A. M., Lluch, A., Vinoy, S., Stafleu, A., Berg, R. V. D., Holst, Jens Juul, Kok, F. J. & Hendriks, H. F. J., 2006, In: American Journal of Physiology: Endocrinology and Metabolism. 290, 2, p. E389-E395Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exendin-4, but not glucagon-like peptide-1, is cleared exclusively by glomerular filtration in anaesthetised pigs
Simonsen, L., Holst, Jens Juul & Deacon, Carolyn F., 2006, In: Diabetologia. 49, 4, p. 706-712 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Feeding an elemental diet vs a milk-based formula does not decrease intestinal mucosal growth in infant pigs
Stoll, B., Price, P. T., Reeds, P. J., Chang, X., Henry, J. F., Goudoever, J. B. V., Holst, Jens Juul & Burrin, D. G., 2006, In: Journal of Parenteral and Enteral Nutrition. 30, 1, p. 32-39 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GIP-(3-42) does not antagonize insulinotropic effects of GIP at physiological concentrations.
Deacon, Carolyn F., Plamboeck, A., Rosenkilde, Mette, de Heer, J. & Holst, Jens Juul, 2006, In: American Journal of Physiology: Endocrinology and Metabolism. 291, 3, p. E468-75Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-2 receptor localizes to enteric neurons and endocrine cells expressing vasoactive peptides and mediates increased blood flow
Guan, X. F., Karpen, H. E., Stephens, J., Bukowski, J. T., Niu, S. Y., Zhang, G. C., Stoll, B., Finegold, M. J., Holst, Jens Juul, Hadsell, D. L., Nichols, B. L. & Burrin, D. G., 2006, In: Today in Medicine. Gastroenterology. 130, 1, p. 150-164 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ghrelin stimulates gastric emptying and hunger in normal-weight humans
Levin, F., Edholm, T., Schmidt, P. T., Gryback, P., Jacobsson, H., Degerblad, M., Hoybye, C., Holst, Jens Juul, Rehfeld, J. F., Hellstrom, P. M. & Naslund, E., 2006, In: Journal of Clinical Endocrinology and Metabolism. 91, 9, p. 3296-3302 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide 1 abolishes the postprandial rise in triglyceride concentrations and lowers levels of non-esterified fatty acids in humans
Meier, J. J., Gethmann, A., Gotze, O., Gallwitz, B., Holst, Jens Juul, Schmidt, W. E. & Nauck, M. A., 2006, In: Diabetologia. 49, 3, p. 452-458 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide 2 stimulates glucagon secretion, enhances lipid absorption, and inhibits gastric acid secretion in humans
Meier, J. J., Nauck, M. A., Pott, A., Heinze, K., Goetze, O., Bulut, K., Schmidt, W. E., Gallwitz, B. & Holst, Jens Juul, 2006, In: Today in Medicine. Gastroenterology. 130, 1, p. 44-54 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-1: From extract to agent. The Claude Bernard Lecture, 2005
Holst, Jens Juul, 2006, In: Diabetologia. 49, 2, p. 253-260 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptides 1 and 2, enteroglucagon, glicentin and oxyntomodulin.
Holst, Jens Juul & Kastin, A., 2006, Handbook of biologically active peptides. Amsterdam: Elsevier, p. 1057-1064 7 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
Glucose-stimulated prehepatic insulin secretion is associated with circulating alanine, triglyceride, glucagons, lactate and TNF-alfa in patients with HIV-lipodystrophy
Haugaard, S. B., Andersen, Ove, Pedersen, S., Dela, Flemming, Holst, Jens Juul, Deacon, Carolyn F., Iversen, J. & Madsbad, Sten, 2006, In: HIV Medicine. 7, p. 163-172 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glycemic and insulinemic responses as determinants of appetite in humans
Flint, A., Møller, B. K., Raben, Anne, Sloth, B., Pedersen, D., Tetens, Inge , Holst, Jens Juul & Astrup, A., 2006, In: American Journal of Clinical Nutrition. 84, 6, p. 1365-1373 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Immunoneutralization of endogenous glucagon reduces hepatic glucose output and improves long-term glycemic control in diabetic ob/ob mice.
Sørensen, H., Brand, C. L., Neschen, S., Holst, Jens Juul, Fosgerau, K., Nishimura, E. & Shulman, G. I., 2006, In: Diabetes. 55, 10, p. 2843-8 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of incretin hormones on beta-cell function in subjects with normal or impaired glucose tolerance
Muscelli, E., Mari, A., Natali, A., Astiarraga, B. D., Camastra, S., Frascerra, S., Holst, Jens Juul & Ferrannini, E., 2006, In: American Journal of Physiology: Endocrinology and Metabolism. 291, 6, p. E1144-E1150Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increased postprandial responses of GLP-1 and GIP in patients with chronic pancreatitis and steatorrhea following pancreatic enzyme substitution.
Knop, F. K., Vilsbøll, Tina, Larsen, S., Højberg, P. V., Vølund, A., Madsbad, Sten, Holst, Jens Juul & Krarup, T., 2006, In: American Journal of Physiology: Endocrinology and Metabolism. 292, 1, p. E324-30Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Incretin mimetics in the treatment of type 2 diabetes mellitus
Holst, Jens Juul & Hughes, T., 2006, European Endocrine Disease 2006. London: Touch Briefings, p. 17-19 2 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
Influence of gastric inhibitory polypeptide on pentagastrin-stimulated gastric acid secretion in patients with type 2 diabetes and healthy controls.
Meier, J. J., Nauck, M. A., Kask, B., Holst, Jens Juul, Deacon, Carolyn F., Schmidt, W. E. & Gallwitz, B., 2006, In: World Journal of Gastroenterology. 12, 12, p. 1874-80 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibitory effect of GLP-1 on gastric motility persists after vagal deafferentation in pigs.
Nagell, C. F., Wettergren, A., Ørskov, Cathrine & Holst, Jens Juul, 2006, In: Scandinavian Journal of Gastroenterology. 41, 6, p. 667-72 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metabolism of glucagon-like peptide-2 in pigs: role of dipeptidyl peptidase IV.
Hansen, L., Hare, K. J., Hartmann, B., Deacon, Carolyn F., Ugleholdt, Randi Kjærsgaard, Plamboeck, A. & Holst, Jens Juul, 2006, In: Regulatory Peptides. 138, 2-3, p. 126-32 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Possible role of adiponectin and insulin sensitivity in mediating the favorable effects of lower body fat mass on blood lipids
Buemann, B., Astrup, A., Pedersen, O., Black, E., Holst, C., Toubro, S., Echwald, S., Holst, Jens Juul, Rasmussen, C. & Sørensen, Thorkild I.A., 2006, In: Journal of Clinical Endocrinology and Metabolism. 91, 5, p. 1698-1704 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prohormone convertase 1/3 is essential for processing of the glucose-dependent insulinotropic polypeptide precursor
Ugleholdt, Randi Kjærsgaard, Poulsen, M. H., Holst, Peter Johannes, Irminger, J., Orskov, C., Pedersen, Jens, Rosenkilde, Mette, Zhu, X., Steiner, D. F. & Holst, Jens Juul, 2006, In: Journal of Biological Chemistry. 281, 16, p. 11050-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Role of GLP-1 analogues and DDP-IV inhibitors in the treatment of type 2 diabetes
Holst, Jens Juul & Deacon, Carolyn F., 2006, In: Avances en Diabetologia. 22, 2, p. 115-125 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Stimulation of glucagon secretion and inhibition of gastric acid secretion by glucagon-like peptide-2 (GLP-2) in healthy human subjects
Meier, J., Nauck, M. A., Pott, A., Heinze, K., Götze, O., Bulut, K., Schmidt, W. E., Gallwitz, B. & Holst, Jens Juul, 2006, In: Today in Medicine. Gastroenterology. 130, p. 44-54Research output: Contribution to journal › Journal article › Research
- Published
Switching from insulin to oral sulfonylureas in patients with diabetes due to Kir6.2 mutations
Pearson, E. R., Flechtner, I., Njolstad, P. R., Malecki, M. T., Flanagan, S. E., Larkin, B., Ashcroft, F. M., Klimes, I., Codner, E., Iotova, V., Slingerland, A. S., Shield, J., Robert, J., Holst, Jens Juul, Clark, P. M., Ellard, S., Sovik, O., Polak, M. & Hattersley, A. T., 2006, In: New England Journal of Medicine. 355, 5, p. 467-477 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Synergistic effect of supplemental enteral nutrients and exogenous glucagon-like peptide 2 on intestinal adaptation in a rat model of short bowel syndrome
Liu, X. W., Nelson, D. W., Holst, Jens Juul & Ney, D. M., 2006, In: American Journal of Clinical Nutrition. 84, 5, p. 1142-1150 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect o a high protein dairy breakfast on the postprandial ghrelin response
Blom, W. A. M., Lluch, A., Stafleu, A., Vinoy, S., Holst, Jens Juul, Schaafsma, G. & Hendriks, H. F. K., 2006, In: Am. J. Clin. Nutr.. 83, p. 211-220Research output: Contribution to journal › Journal article › Research
- Published
The effects of gastric emptying on the postprandial ghrelin response
Blom, W., Lluch, A., Vinoy, S., Stafleu, A., Van den Berg, R., Holst, Jens Juul, Kok, F. J. & Hendriks, H. F. K., 2006, In: Am. J. Physiol.. 290, p. E389-E395Research output: Contribution to journal › Journal article › Research
- Published
The elimination rates of intact GIP as well as its primary metabolite, GIP 3-42, are similar in type 2 diabetic patients and healthy subjects.
Vilsbøll, Tina, Agersø, H., Lauritsen, T., Deacon, Carolyn F., Aaboe, K., Madsbad, Sten, Krarup, T. & Holst, Jens Juul, 2006, In: Regulatory Peptides. 137, 3, p. 168-72 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The glucagon-like peptide-1 metabolite GLP-1-(9-36) amide reduces postprandial glycemia independently of gastric emptying and insulin secretion in humans.
Meier, J. J., Gethmann, A., Nauck, M. A., Götze, O., Schmitz, F., Deacon, Carolyn F., Gallwitz, B., Schmidt, W. E. & Holst, Jens Juul, 2006, In: American Journal of Physiology: Endocrinology and Metabolism. 290, 6, p. E1118-23Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The metabolite generated by dipeptidyl-peptidase 4 metabolism of glucagon-like peptide-1 has no influence on plasma glucose levels in patients with type 2 diabetes
Zander, M., Madsbad, S., Deacon, Carolyn F. & Holst, Jens Juul, 2006, In: Diabetologia. 49, 2, p. 369-374 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The rate of intestinal glucose absorption is correlated with plasma glucose-dependent insulinotropic polypeptide concentrations in healthy men
Wachters-Hagedoorn, R. E., Priebe, M. G., Heimweg, J. A. J., Heiner, A. M., Englyst, K. N., Holst, Jens Juul, Stellaard, F. & Vonk, R. J., 2006, In: Journal of Nutrition. 136, 6, p. 1511-1516 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The successful transfer of insulin treated patients with diabetes due to Kir6.2 (KCNJ11) mutations to oral sulfonylureas
Pearson, E. R., Flechtner, I., Njølståd, P. R., Malecki, M. T., Flanagan, S., Larkin, B., Ashcroft, F. M., Klimes, I., Codner, E., Iotova, V., Slingerland, A. S., Shield, J., Robert, J. J., Holst, Jens Juul, Clark, P. M., Ellard, S. E., Sovik, O., Polak, M. & Hattersley, A. T., 2006, In: N. Engl. J. Med.. 355, p. 467-477Research output: Contribution to journal › Journal article › Research
- Published
Vagal afferents are essential for maximal resection-induced intestinal adaptive growth in orally fed rats
Nelson, D. W., Liu, X. W., Holst, Jens Juul, Raybould, H. E. & Ney, D. M., 2006, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 291, 5, p. R1256-R1264Research output: Contribution to journal › Journal article › Research › peer-review
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Meal induced gut hormone secretion is altered in aerobically trained compared to sedentary young healthy males
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Copenhagen study of overweight patients with coronary artery disease undergoing low energy diet or interval training: the randomized CUT-IT trial protocol
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Whole grain-rich diet reduces body weight and systemic low-grade inflammation without inducing major changes of the gut microbiome: a randomised cross-over trial
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