Kei Sakamoto

Kei Sakamoto

Professor

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    51 - 75 out of 145Page size: 25
    1. 2015
    2. Published

      SIK2 regulates CRTCs, HDAC4 and glucose uptake in adipocytes

      Henriksson, E., Säll, J., Gormand, A., Wasserstrom, S., Morrice, N. A., Fritzen, Andreas Mæchel, Foretz, M., Campbell, D. G., Sakamoto, Kei, Ekelund, M., Degerman, E., Stenkula, K. G. & Göransson, O., 2015, In: Journal of Cell Science. 128, 3, p. 472-486 15 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. 2014

    4. The LKB1-salt-inducible kinase pathway functions as a key gluconeogenic suppressor in the liver

      Patel, K., Foretz, M., Marion, A., Campbell, D. G., Gourlay, R., Boudaba, N., Tournier, E., Titchenell, P., Peggie, M., Deak, M., Wan, M., Kaestner, K. H., Göransson, O., Viollet, B., Gray, N. S., Birnbaum, M. J., Sutherland, C. & Sakamoto, Kei, 4 Aug 2014, In: Nature Communications. 5, 4535.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Mechanism of action of compound-13: An α1-selective small molecule activator of AMPK

      Hunter, R. W., Foretz, M., Bultot, L., Fullerton, M. D., Deak, M., Ross, F. A., Hawley, S. A., Shpiro, N., Viollet, B., Barron, D., Kemp, B. E., Steinberg, G. R., Hardie, D. G. & Sakamoto, Kei, 17 Jul 2014, In: Chemistry and Biology. 21, 7, p. 866-879 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Structural basis for the recruitment of glycogen synthase by glycogenin

      Zeqiraj, E., Tang, X., Hunter, R. W., García-Rocha, M., Judd, A., Deak, M., Von Wilamowitz-Moellendorff, A., Kurinov, I., Guinovart, J. J., Tyers, M., Sakamoto, Kei & Sicheri, F., 15 Jul 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 28, p. E2831-E2840

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. A-769662 potentiates the effect of other AMP-activated protein kinase activators on cardiac glucose uptake

      Timmermans, A. D., Balteau, M., Gélinas, R., Renguet, E., Ginion, A., de Meester, C., Sakamoto, Kei, Balligand, J. L., Bontemps, F., Vanoverschelde, J. L., Horman, S., Beauloye, C. & Bertrand, L., 15 Jun 2014, In: American Journal of Physiology - Heart and Circulatory Physiology. 306, 12, p. H1619-H1630

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. The Ca2+/calmodulin-dependent kinase kinase β-AMP-activated protein kinase-α1 pathway regulates phosphorylation of cytoskeletal targets in thrombin-stimulated human platelets

      Onselaer, M. B., Oury, C., Hunter, R. W., Eeckhoudt, S., Barile, N., Lecut, C., Morel, N., Viollet, B., Jacquet, L. M., Bertrand, L., Sakamoto, Kei, Vanoverschelde, J. L., Beauloye, C. & Horman, S., Jun 2014, In: Journal of Thrombosis and Haemostasis. 12, 6, p. 973-986 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Enhanced activation of cellular AMPK by dual-small molecule treatment: AICAR and A769662

      Ducommun, S., Ford, R. J., Bultot, L., Deak, M., Bertrand, L., Kemp, B. E., Steinberg, G. R. & Sakamoto, Kei, 15 Mar 2014, In: American Journal of Physiology - Endocrinology and Metabolism. 306, 6, p. E688-E696

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Mutation in the γ2-Subunit of AMP-activated protein kinase stimulates cardiomyocyte proliferation and hypertrophy independent of glycogen storage

      Kim, M., Hunter, R. W., Garcia-Menendez, L., Gong, G., Yang, Y. Y., Kolwicz, S. C., Xu, J., Sakamoto, Kei, Wang, W. & Tian, R., 14 Mar 2014, In: Circulation Research. 114, 6, p. 966-975 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Investigation of LKB1 Ser431 phosphorylation and Cys 433 farnesylation using mouse knockin analysis reveals an unexpected role of prenylation in regulating AMPK activity

      Houde, V. P., Ritorto, M. S., Gourlay, R., Varghese, J., Davies, P., Shpiro, N., Sakamoto, Kei & Alessi, D. R., 15 Jan 2014, In: Biochemical Journal. 458, 1, p. 41-56 16 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Role of AMP-activated protein kinase in regulating hypoxic survival and proliferation of mesenchymal stem cells

      De Meester, C., Timmermans, A. D., Balteau, M., Ginion, A., Roelants, V., Noppe, G., Porporato, P. E., Sonveaux, P., Viollet, B., Sakamoto, Kei, Feron, O., Horman, S., Vanoverschelde, J. L., Beauloye, C. & Bertrand, L., 1 Jan 2014, In: Cardiovascular Research. 101, 1, p. 20-29 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Salicylic acid: old and new implications for the treatment of type 2 diabetes?

      Rena, G. & Sakamoto, Kei, 1 Jan 2014, In: Diabetology International. 5, 4, p. 212-218 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. 2013

    15. Glucose-6-phosphate-mediated activation of liver glycogen synthase plays a key role in hepatic glycogen synthesis

      Von Wilamowitz-Moellendorff, A., Hunter, R. W., García-Rocha, M., Kang, L., López-Soldado, I., Lantier, L., Patel, K., Peggie, M. W., Martínez-Pons, C., Voss, M., Calbó, J., Cohen, P. T. W., Wasserman, D. H., Guinovart, J. J. & Sakamoto, Kei, 1 Dec 2013, In: Diabetes. 62, 12, p. 4070-4082 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Molecular mechanism of action of metformin: Old or new insights?

      Rena, G., Pearson, E. R. & Sakamoto, Kei, 1 Sep 2013, In: Diabetologia. 56, 9, p. 1898-1906 9 p.

      Research output: Contribution to journal › Review › Research › peer-review

    17. AMPKα1 regulates macrophage skewing at the time of resolution of inflammation during skeletal muscle regeneration

      Mounier, R., Théret, M., Arnold, L., Cuvellier, S., Bultot, L., Göransson, O., Sanz, N., Ferry, A., Sakamoto, Kei, Foretz, M., Viollet, B. & Chazaud, B., 6 Aug 2013, In: Cell Metabolism. 18, 2, p. 251-264 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. A noncanonical, GSK3-independent pathway controls postprandial hepatic glycogen deposition

      Wan, M., Leavens, K. F., Hunter, R. W., Koren, S., Von Wilamowitz-Moellendorff, A., Lu, M., Satapati, S., Chu, Q., Sakamoto, Kei, Burgess, S. C. & Birnbaum, M. J., 2 Jul 2013, In: Cell Metabolism. 18, 1, p. 99-105 7 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Dual regulation of glycogen synthase kinase 3 (GSK3)α/β by protein kinase C (PKC)α and Akt promotes thrombin-mediated integrin α∥bβ3 activation and granule secretion in platelets

      Moore, S. F., Van Den Bosch, M. T. J., Hunter, R. W., Sakamoto, Kei, Poole, A. W. & Hers, I., 8 Feb 2013, In: Journal of Biological Chemistry. 288, 6, p. 3918-3928 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      AS160 deficiency causes whole-body insulin resistance via composite effects in multiple tissues

      Wang, H. Y., Ducommun, S., Quan, C., Xie, B., Li, M., Wasserman, D. H., Sakamoto, Kei, Mackintosh, C. & Chen, S., 15 Jan 2013, In: Biochemical Journal. 449, 2, p. 479-489 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      LKB1 regulates lipid oxidation during exercise independently of AMPK

      Jeppesen, J. F., Maarbjerg, S. J., Jordy, A. B., Fritzen, Andreas Mæchel, Pehmøller, C., Sylow, Lykke, Serup, A. K. L., Jessen, N., Thorsen, K., Prats Gavalda, Clara, Qvortrup, Klaus, Dyck, J. R. B., Hunter, R. W., Sakamoto, Kei, Thomson, D. M., Schjerling, Peter, Wojtaszewski, Jørgen F P, Richter, Erik A. & Kiens, Bente, 2013, In: Diabetes. 62, 5, p. 1490-1499 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. 2012
    23. Published

      Analysis of substrate specificity and cyclin Y binding of PCTAIRE-1 kinase

      Shehata, S. N., Hunter, R. W., Ohta, E., Peggie, M. W., Lou, H. J., Sicheri, F., Zeqiraj, E., Turk, B. E. & Sakamoto, Kei, 1 Nov 2012, In: Cellular Signalling. 24, 11, p. 2085-2094 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Reduced AMPK-ACC and mTOR signaling in muscle from older men, and effect of resistance exercise

      Li, M., Verdijk, L. B., Sakamoto, Kei, Ely, B., van Loon, L. J. C. & Musi, N., 1 Nov 2012, In: Mechanisms of Ageing and Development. 133, 11-12, p. 655-664 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      Effect of acute exercise on glycogen synthase in muscle from obese and diabetic subjects

      Jensen, J., Tantiwong, P., Stuenæs, J. T., Molina-Carrion, M., de Fronzo, R. A., Sakamoto, Kei & Musi, N., 1 Jul 2012, In: American Journal of Physiology - Endocrinology and Metabolism. 303, 1, p. E82-E89

      Research output: Contribution to journal › Journal article › Research › peer-review

    26. Published

      The AMPK-related kinase SIK2 is regulated by cAMP via phosphorylation at Ser 358 in adipocytes

      Henriksson, E., Jones, H. A., Patel, K., Peggie, M., Morrice, N., Sakamoto, Kei & Göransson, O., 15 Jun 2012, In: Biochemical Journal. 444, 3, p. 503-514 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    27. Cellular responses to the metal-binding properties of metformin

      Logie, L., Harthill, J., Patel, K., Bacon, S., Hamilton, D. L., Macrae, K., McDougall, G., Wang, H. H., Xue, L., Jiang, H., Sakamoto, Kei, Prescott, A. R. & Rena, G., 1 Jun 2012, In: Diabetes. 61, 6, p. 1423-1433 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    28. Aspirin inhibits mTOR signaling, activates AMP-activated protein kinase, and induces autophagy in colorectal cancer cells

      Din, F. V. N., Valanciute, A., Houde, V. P., Zibrova, D., Green, K. A., Sakamoto, Kei, Alessi, D. R. & Dunlop, M. G., Jun 2012, In: Gastroenterology. 142, 7, p. 1504-1515.e3

      Research output: Contribution to journal › Journal article › Research › peer-review

    29. The ancient drug salicylate directly activates AMP-activated protein kinase

      Hawley, S. A., Fullerton, M. D., Ross, F. A., Schertzer, J. D., Chevtzoff, C., Walker, K. J., Peggie, M. W., Zibrova, D., Green, K. A., Mustard, K. J., Kemp, B. E., Sakamoto, Kei, Steinberg, G. R. & Hardie, D. G., 18 May 2012, In: Science. 336, 6083, p. 918-922 5 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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