Tuomas Oskari Kilpeläinen
Associate Professor
Kilpeläinen Group
Blegdamsvej 3B, Mærsk Tårnet, 8. sal
2200 København N.
- 2007
- Published
Epidemiological studies of exercise in diabetes prevention
Hu, G., Lakka, T. A., Kilpeläinen, Tuomas O. & Tuomilehto, J., Jun 2007, In: Applied Physiology, Nutrition and Metabolism. 32, 3, p. 583-95 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Physical activity modifies the effect of SNPs in the SLC2A2 (GLUT2) and ABCC8 (SUR1) genes on the risk of developing type 2 diabetes
Kilpeläinen, Tuomas O., Lakka, T. A., Laaksonen, D. E., Laukkanen, O., Lindström, J., Eriksson, J. G., Valle, T. T., Hämäläinen, H., Aunola, S., Ilanne-Parikka, P., Keinänen-Kiukaanniemi, S., Tuomilehto, J., Uusitupa, M., Laakso, M. & Finnish Diabetes Prevention Study Group, F. D. P. S. G., 22 Oct 2007, In: Physiological Genomics. 31, 2, p. 264-72 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2008
- Published
SNPs in PPARG associate with type 2 diabetes and interact with physical activity
Kilpeläinen, Tuomas O., Lakka, T. A., Laaksonen, D. E., Lindström, J., Eriksson, J. G., Valle, T. T., Hämäläinen, H., Ilanne-Parikka, P., Keinänen-Kiukaanniemi, S., Lindi, V., Tuomilehto, J., Uusitupa, M. & Laakso, M., Jan 2008, In: Medicine and Science in Sports and Exercise. 40, 1, p. 25-33 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interaction of single nucleotide polymorphisms in ADRB2, ADRB3, TNF, IL6, IGF1R, LIPC, LEPR, and GHRL with physical activity on the risk of type 2 diabetes mellitus and changes in characteristics of the metabolic syndrome: The Finnish Diabetes Prevention Study
Kilpeläinen, Tuomas O., Lakka, T. A., Laaksonen, D. E., Mager, U., Salopuro, T., Kubaszek, A., Todorova, B., Laukkanen, O., Lindström, J., Eriksson, J. G., Hämäläinen, H., Aunola, S., Ilanne-Parikka, P., Keinänen-Kiukaanniemi, S., Tuomilehto, J., Laakso, M., Uusitupa, M. & Finnish Diabetes Prevention Study Group, F. D. P. S. G., Mar 2008, In: Metabolism. 57, 3, p. 428-36 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2009
- Published
Association of variants in the PCSK1 gene with obesity in the EPIC-Norfolk study
Kilpeläinen, Tuomas O., Bingham, S. A., Khaw, K., Wareham, N. J. & Loos, R. J. F., 15 Sep 2009, In: Human Molecular Genetics. 18, 18, p. 3496-501 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2010
- Published
Hundreds of variants clustered in genomic loci and biological pathways affect human height
Lango Allen, H., Estrada, K., Lettre, G., Berndt, S. I., Weedon, M. N., Rivadeneira, F., Willer, C. J., Jackson, A. U., Vedantam, S., Raychaudhuri, S., Ferreira, T., Wood, A. R., Weyant, R. J., Segrè, A. V., Speliotes, E. K., Wheeler, E., Soranzo, N., Park, J-H., Yang, J., Gudbjartsson, D. & 273 others, , 14 Oct 2010, In: Nature. 467, 7317, p. 832-8 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The rs1800629 polymorphism in the TNF gene interacts with physical activity on the changes in C-reactive protein levels in the Finnish Diabetes Prevention Study
Kilpeläinen, Tuomas O., Laaksonen, D. E., Lakka, T. A., Herder, C., Koenig, W., Lindström, J., Eriksson, J. G., Uusitupa, M., Kolb, H., Laakso, M., Tuomilehto, J. & Finnish Diabetes Prevention Study, F. D. P. S., Nov 2010, In: Experimental and Clinical Endocrinology and Diabetes. 118, 10, p. 757-9 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index
Speliotes, E. K., Willer, C. J., Berndt, S. I., Monda, K. L., Thorleifsson, G., Jackson, A. U., Allen, H. L., Lindgren, C. M., Luan, J., Mägi, R., Randall, J. C., Vedantam, S., Winkler, T. W., Lu, Q., Workalemahu, T., Heid, I. M., Steinthorsdottir, V., Stringham, H. M., Weedon, M. N., Wheeler, E. & 31 others, , 1 Nov 2010, In: Nature Genetics. 42, 11, p. 937-48 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution
Heid, I. M., Jackson, A. U., Randall, J. C., Winkler, T. W., Qi, L., Steinthorsdottir, V., Thorleifsson, G., Zillikens, M. C., Speliotes, E. K., Mägi, R., Workalemahu, T., White, C. C., Bouatia-Naji, N., Harris, T. B., Berndt, S. I., Ingelsson, E., Willer, C. J., Weedon, M. N., Luan, J., Vedantam, S. & 31 others, , 1 Nov 2010, In: Nature Genetics. 42, 11, p. 949-60 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies
Elks, C. E., Perry, J. R. B., Sulem, P., Chasman, D. I., Franceschini, N., He, C., Lunetta, K. L., Visser, J. A., Byrne, E. M., Cousminer, D. L., Gudbjartsson, D. F., Esko, T., Feenstra, B., Hottenga, J-J., Koller, D. L., Kutalik, Z., Lin, P., Mangino, M., Marongiu, M., McArdle, P. F. & 31 others, , Dec 2010, In: Nature Genetics. 42, 12, p. 1077-85 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
- Published
Genome-wide association studies and human population obesity
Kilpeläinen, Tuomas O. & Loos, R. J., 2011, Obesity before Birth: Maternal and prenatal influences on the offspring. Lustig, R. H. (ed.). New York, USA: Springer, p. 95-112 (Endocrine Updates, Vol. 30).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
Obesity-susceptibility loci have a limited influence on birth weight: a meta-analysis of up to 28,219 individuals
Kilpeläinen, Tuomas O., den Hoed, M., Ong, K. K., Grøntved, A., Brage, S., Jameson, K., Cooper, C., Khaw, K., Ekelund, U., Wareham, N. J., Loos, R. J. F. & Early Growth Genetics Consortium, E. G. G. C., Apr 2011, In: American Journal of Clinical Nutrition. 93, 4, p. 851-60 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic variation near IRS1 associates with reduced adiposity and an impaired metabolic profile
Oskari Kilpeläinen, T., Zillikens, M. C., Stančákova, A., Finucane, F. M., Ried, J. S., Langenberg, C., Zhang, W., Beckmann, J. S., Luan, J., Vandenput, L., Styrkarsdottir, U., Zhou, Y., Smith, A. V., Zhao, J-H., Amin, N., Vedantam, S., Shin, S-Y., Haritunians, T., Fu, M., Feitosa, M. F. & 97 others, , Aug 2011, In: Nature Genetics. 43, 8, p. 753-60 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Physical Activity Attenuates the Influence of FTO Variants on Obesity Risk: A Meta-Analysis of 218,166 Adults and 19,268 Children
Oskari Kilpeläinen, T., Qi, L., Brage, S., Sharp, S. J., Sonestedt, E., Demerath, E., Ahmad, T., Mora, S., Kaakinen, M., Sandholt, C. H., Holzapfel, C., Autenrieth, C. S., Hyppönen, E., Cauchi, S., He, M., Kutalik, Z., Kumari, M., Stancáková, A., Meidtner, K., Balkau, B. & 96 others, , 1 Nov 2011, In: P L o S Medicine (Online). 8, 11, p. e1001116Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
- Published
The metabochip, a custom genotyping array for genetic studies of metabolic, cardiovascular, and anthropometric traits
Voight, B. F., Kang, H. M., Ding, J., Palmer, C. D., Sidore, C., Chines, P. S., Burtt, N. P., Fuchsberger, C., Li, Y., Erdmann, J., Frayling, T. M., Heid, I. M., Jackson, A. U., Johnson, T., Oskari Kilpeläinen, T., Lindgren, C. M., Morris, A. P., Prokopenko, I., Randall, J. C., Saxena, R. & 29 others, , 2012, In: P L o S Genetics (Online). 8, 8, p. e1002793Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association of genetic variation in FTO with risk of obesity and type 2 diabetes with data from 96,551 East and South Asians
Li, H., Oskari Kilpeläinen, T., Liu, C., Zhu, J., Liu, Y., Hu, C., Yang, Z., Zhang, W., Bao, W., Cha, S-T., Wu, Y., Yang, T., Sekine, A., Choi, B. Y., Yajnik, C. S., Zhou, D., Takeuchi, F., Yamamoto, K., Chan, J. C., Mani, K. R. & 45 others, , Apr 2012, In: Diabetologia. 55, 4, p. 981-95 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
- Published
New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism
Horikoshi, M., Yaghootkar, H., Mook-Kanamori, D. O., Sovio, U., Taal, H. R., Hennig, B. J., Bradfield, J. P., St Pourcain, B., Evans, D. M., Charoen, P., Kaakinen, M., Cousminer, D. L., Lehtimäki, T., Kreiner-Møller, E., Warrington, N. M., Bustamante, M., Feenstra, B., Berry, D. J., Thiering, E., Pfab, T. & 31 others, , 2013, In: Nature Genetics. 45, 1, p. 76-82 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sex-stratified Genome-wide Association Studies Including 270,000 Individuals Show Sexual Dimorphism in Genetic Loci for Anthropometric Traits
Randall, J. C., Winkler, T. W., Kutalik, Z., Berndt, S. I., Jackson, A. U., Monda, K. L., Oskari Kilpeläinen, T., Esko, T., Mägi, R., Li, S., Workalemahu, T., Feitosa, M. F., Croteau-Chonka, D. C., Day, F. R., Fall, T., Ferreira, T., Gustafsson, S., Locke, A. E., Mathieson, I., Scherag, A. & 31 others, , Jun 2013, In: P L o S Genetics. 9, 6, p. 1-19 20 p., e1003500.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Common sources of bias in gene-lifestyle interaction studies of cardiometabolic disease
Kilpeläinen, Tuomas O., 29 Sep 2013, In: Current Nutrition Reports. 2, p. 251-257Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Whole-exome sequencing of 2,000 Danish individuals and the role of rare coding variants in type 2 diabetes
Lohmueller, K. E., Sparsø, T. H., Li, Q., Galijatovic, E. A. A., Korneliussen, T. S., Albrechtsen, A., Banasik, K., Grarup, N., Hallgrimsdottir, I., Kiil, K., Oskari Kilpeläinen, T., Krarup, N. T., Pers, T. H., Sanchez, G., Hu, Y., DeGiorgio, M., Jørgensen, T., Sandbæk, A., Lauritzen, T., Brunak, S. & 6 others, , 5 Dec 2013, In: American Journal of Human Genetics. 93, 6, p. 1072-1086 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
Gene-physical activity interactions and their impact on diabetes
Kilpeläinen, Tuomas O. & Franks, P. W., 2014, In: Medicine and Sport Science. 60, p. 94-103 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pleiotropic genes for metabolic syndrome and inflammation
Kraja, A. T., Chasman, D. I., North, K. E., Reiner, A. P., Yanek, L. R., Oskari Kilpeläinen, T., Smith, J. A., Dehghan, A., Dupuis, J., Johnson, A. D., Feitosa, M. F., Tekola-Ayele, F., Chu, A. Y., Nolte, I. M., Dastani, Z., Morris, A., Pendergrass, S. A., Sun, Y. V., Ritchie, M. D., Vaez, A. & 31 others, , 2014, In: Molecular Genetics and Metabolism. 112, 4, p. 317-38 22 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide association study of sexual maturation in males and females highlights a role for body mass and menarche loci in male puberty
The ReproGen Consortium, T. R. C., The Early Growth Genetics (EGG) Consortium, T. E. G. G. (. C., The Early Growth Genetics (EGG) Consortium, T. E. G. G. (. C., The ReproGen Consortium, T. R. C. & The GIANT Consortium, T. G. C., 1 Jan 2014, In: Human Molecular Genetics. 23, 16, p. 4452-4464 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quality control and conduct of genome-wide association meta-analyses
Winkler, T. W., Day, F. R., Croteau-Chonka, D. C., Wood, A. R., Locke, A. E., Mägi, R., Ferreira, T., Fall, T., Graff, M., Justice, A. E., Luan, J., Gustafsson, S., Randall, J. C., Vedantam, S., Workalemahu, T., Kilpeläinen, T., Scherag, A., Esko, T., Kutalik, Z., Heid, I. M. & 2 others, , May 2014, In: Nature Protocols (Online). 9, 5, p. 1192-1212 21 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
FTO genetic variants, dietary intake and body mass index: insights from 177 330 individuals
Qi, Q., Oskari Kilpeläinen, T., Downer, M. K., Tanaka, T., Smith, C. E., Sluijs, I., Sonestedt, E., Chu, A. Y., Renström, F., Lin, X., Angquist, L. H., Huang, J., Liu, Z., Li, Y., Asif Ali, M., Xu, M., Ahluwalia, T. V. S., Boer, J. M. A., Chen, P., Daimon, M. & 89 others, , 7 Aug 2014, In: Human Molecular Genetics. 23, 25, p. 6961-6972 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 37677655
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Genome-wide physical activity interactions in adiposity ― A meta-analysis of 200,452 adults
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Dietary intake, FTO genetic variants and adiposity: a combined analysis of over 16,000 children and adolescents
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Genetic Correlation between Body Fat Percentage and Cardiorespiratory Fitness Suggests Common Genetic Etiology
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