Human Malformed Perinatal Anthropological Crania Contribute to New Insight in the Extension of Bone Malformations in Cranial Development

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Human Malformed Perinatal Anthropological Crania Contribute to New Insight in the Extension of Bone Malformations in Cranial Development. / Kjær, Inger; Marin, Amberley; Meyer, Ion.

In: Fetal and Pediatric Pathology, 2024, p. 1-13.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Kjær, I, Marin, A & Meyer, I 2024, 'Human Malformed Perinatal Anthropological Crania Contribute to New Insight in the Extension of Bone Malformations in Cranial Development', Fetal and Pediatric Pathology, pp. 1-13. https://doi.org/10.1080/15513815.2024.2338434

APA

Kjær, I., Marin, A., & Meyer, I. (2024). Human Malformed Perinatal Anthropological Crania Contribute to New Insight in the Extension of Bone Malformations in Cranial Development. Fetal and Pediatric Pathology, 1-13. https://doi.org/10.1080/15513815.2024.2338434

Vancouver

Kjær I, Marin A, Meyer I. Human Malformed Perinatal Anthropological Crania Contribute to New Insight in the Extension of Bone Malformations in Cranial Development. Fetal and Pediatric Pathology. 2024;1-13. https://doi.org/10.1080/15513815.2024.2338434

Author

Kjær, Inger ; Marin, Amberley ; Meyer, Ion. / Human Malformed Perinatal Anthropological Crania Contribute to New Insight in the Extension of Bone Malformations in Cranial Development. In: Fetal and Pediatric Pathology. 2024 ; pp. 1-13.

Bibtex

@article{8f14577ceb56412ba9964d83f15d78bc,
title = "Human Malformed Perinatal Anthropological Crania Contribute to New Insight in the Extension of Bone Malformations in Cranial Development",
abstract = "IntroductionWe describe five abnormal crania which may provide more diagnostic data for assessment of abnormal crania in newborns.MethodsFive malformed perinatal crania from the Saxtorphian Collection are described using published prenatal abnormal cranial development criteria. These malformations were compared to normal cranial development arising from the migration of neural crest cells. Visual and photographic investigations were performed.ResultsThe malformed crania were occipital encephalocele, holoprosencephaly, anencephaly, and two without a recognizable diagnosis. The anthropological crania were malformed in the same regions as formerly observed in fetal pathology. These regions were comparable to fields formed during normal cell migration from the neural crest. This has seemingly not previously been demonstrated. One undiagnosed cranium may represent a Treacher Collins syndrome (Case 3). The other undiagnosed cranium (Case 4) could be from a scaphocephalic specimen.DiscussionSharp borderlines between malformed and non-malformed regions in cranial syndromes may enable improvement in diagnostics.",
author = "Inger Kj{\ae}r and Amberley Marin and Ion Meyer",
year = "2024",
doi = "10.1080/15513815.2024.2338434",
language = "English",
pages = "1--13",
journal = "Fetal and Pediatric Pathology",
issn = "1551-3815",
publisher = "Taylor & Francis",

}

RIS

TY - JOUR

T1 - Human Malformed Perinatal Anthropological Crania Contribute to New Insight in the Extension of Bone Malformations in Cranial Development

AU - Kjær, Inger

AU - Marin, Amberley

AU - Meyer, Ion

PY - 2024

Y1 - 2024

N2 - IntroductionWe describe five abnormal crania which may provide more diagnostic data for assessment of abnormal crania in newborns.MethodsFive malformed perinatal crania from the Saxtorphian Collection are described using published prenatal abnormal cranial development criteria. These malformations were compared to normal cranial development arising from the migration of neural crest cells. Visual and photographic investigations were performed.ResultsThe malformed crania were occipital encephalocele, holoprosencephaly, anencephaly, and two without a recognizable diagnosis. The anthropological crania were malformed in the same regions as formerly observed in fetal pathology. These regions were comparable to fields formed during normal cell migration from the neural crest. This has seemingly not previously been demonstrated. One undiagnosed cranium may represent a Treacher Collins syndrome (Case 3). The other undiagnosed cranium (Case 4) could be from a scaphocephalic specimen.DiscussionSharp borderlines between malformed and non-malformed regions in cranial syndromes may enable improvement in diagnostics.

AB - IntroductionWe describe five abnormal crania which may provide more diagnostic data for assessment of abnormal crania in newborns.MethodsFive malformed perinatal crania from the Saxtorphian Collection are described using published prenatal abnormal cranial development criteria. These malformations were compared to normal cranial development arising from the migration of neural crest cells. Visual and photographic investigations were performed.ResultsThe malformed crania were occipital encephalocele, holoprosencephaly, anencephaly, and two without a recognizable diagnosis. The anthropological crania were malformed in the same regions as formerly observed in fetal pathology. These regions were comparable to fields formed during normal cell migration from the neural crest. This has seemingly not previously been demonstrated. One undiagnosed cranium may represent a Treacher Collins syndrome (Case 3). The other undiagnosed cranium (Case 4) could be from a scaphocephalic specimen.DiscussionSharp borderlines between malformed and non-malformed regions in cranial syndromes may enable improvement in diagnostics.

U2 - 10.1080/15513815.2024.2338434

DO - 10.1080/15513815.2024.2338434

M3 - Journal article

C2 - 38817107

SP - 1

EP - 13

JO - Fetal and Pediatric Pathology

JF - Fetal and Pediatric Pathology

SN - 1551-3815

ER -

ID: 393264253