Insulin stimulation regulates AS160 and TBC1D1 phosphorylation sites in human skeletal muscle
Research output: Contribution to journal › Journal article › Research › peer-review
Individuals with obesity and type 2 diabetes (T2D) are typically insulin resistant, exhibiting impaired skeletal muscle glucose uptake. Animal and cell culture experiments have shown that site-specific phosphorylation of the Rab-GTPase-activating proteins AS160 and TBC1D1 is critical for GLUT4 translocation facilitating glucose uptake, but their regulation in human skeletal muscle is not well understood.
Original language | English |
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Journal | Nutrition and Diabetes |
Volume | 3 |
Issue number | 74 |
Pages (from-to) | e74 |
ISSN | 2044-4052 |
DOIs | |
Publication status | Published - Jun 2013 |
ID: 51255343