Silencing Metabolic Disorders by Novel SIRT1 Activators
Research output: Contribution to journal › Letter › Research › peer-review
SIRT1, a NAD+-dependent protein deacetylase that regulates transcription factors involved in key cellular processes, has been implicated as a mediator of the beneficial effects of calorie restriction. In a recent issue of Nature, Milne et al. (2007) describe novel potent activators of SIRT1, whose administration to insulin-resistant animals improves glucose homeostasis.
Original language | English |
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Journal | Cell Metabolism |
Volume | 7 |
Issue number | 1 |
Pages (from-to) | 3-4 |
Number of pages | 2 |
ISSN | 1550-4131 |
DOIs | |
Publication status | Published - 9 Jan 2008 |
Externally published | Yes |
ID: 239583846