Strenuous physical exercise adversely affects monocyte chemotaxis
Research output: Contribution to journal › Journal article › Research › peer-review
Physical exercise is important for proper cardiovascular function and disease prevention, but it may influence the immune system. We evaluated the effect of strenuous exercise on monocyte chemotaxis. Monocytes were isolated from blood of 13 young, healthy, sedentary individuals participating in a three-week training program which consisted of repeated exercise bouts. Monocyte chemotaxis and serological biomarkers were investigated at baseline, after three weeks training and after four weeks recovery. Chemotaxis towards vascular endothelial growth factor-A (VEGF-A) and transforming growth factor-ß1 (TGF-ß1) was completely inhibited immediately after training (p
| Original language | English |
|---|---|
| Journal | Thrombosis and Haemostasis |
| Volume | 105 |
| Issue number | 1 |
| Pages (from-to) | 122-30 |
| Number of pages | 9 |
| ISSN | 0340-6245 |
| DOIs | |
| Publication status | Published - Jan 2011 |
- Adaptation, Physiological, Body Mass Index, Chemokine CCL2, Chemotaxis, Leukocyte, Exercise, Humans, Lipids, Monocytes, Nitric Oxide, Observation, Respiratory Function Tests, Transforming Growth Factor beta1, Vascular Endothelial Growth Factor A
Research areas
ID: 45577246