Time-restricted feeding alters lipid and amino acid metabolite rhythmicity without perturbing clock gene expression: [Author Correction]

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Time-restricted feeding alters lipid and amino acid metabolite rhythmicity without perturbing clock gene expression : [Author Correction]. / Lundell, Leonidas S; Parr, Evelyn B; Devlin, Brooke L; Ingerslev, Lars R; Altıntaş, Ali; Sato, Shogo; Sassone-Corsi, Paolo; Barrès, Romain; Zierath, Juleen R; Hawley, John A.

In: Nature Communications, Vol. 11, No. 1, 4643, 2020.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Lundell, LS, Parr, EB, Devlin, BL, Ingerslev, LR, Altıntaş, A, Sato, S, Sassone-Corsi, P, Barrès, R, Zierath, JR & Hawley, JA 2020, 'Time-restricted feeding alters lipid and amino acid metabolite rhythmicity without perturbing clock gene expression: [Author Correction]', Nature Communications, vol. 11, no. 1, 4643. https://doi.org/10.1038/s41467-020-18412-w

APA

Lundell, L. S., Parr, E. B., Devlin, B. L., Ingerslev, L. R., Altıntaş, A., Sato, S., Sassone-Corsi, P., Barrès, R., Zierath, J. R., & Hawley, J. A. (2020). Time-restricted feeding alters lipid and amino acid metabolite rhythmicity without perturbing clock gene expression: [Author Correction]. Nature Communications, 11(1), [4643]. https://doi.org/10.1038/s41467-020-18412-w

Vancouver

Lundell LS, Parr EB, Devlin BL, Ingerslev LR, Altıntaş A, Sato S et al. Time-restricted feeding alters lipid and amino acid metabolite rhythmicity without perturbing clock gene expression: [Author Correction]. Nature Communications. 2020;11(1). 4643. https://doi.org/10.1038/s41467-020-18412-w

Author

Lundell, Leonidas S ; Parr, Evelyn B ; Devlin, Brooke L ; Ingerslev, Lars R ; Altıntaş, Ali ; Sato, Shogo ; Sassone-Corsi, Paolo ; Barrès, Romain ; Zierath, Juleen R ; Hawley, John A. / Time-restricted feeding alters lipid and amino acid metabolite rhythmicity without perturbing clock gene expression : [Author Correction]. In: Nature Communications. 2020 ; Vol. 11, No. 1.

Bibtex

@article{d650310ac18c4c5e98f84ab1fd8249d3,
title = "Time-restricted feeding alters lipid and amino acid metabolite rhythmicity without perturbing clock gene expression: [Author Correction]",
abstract = "Time-restricted feeding (TRF) improves metabolism independent of dietary macronutrient composition or energy restriction. To elucidate mechanisms underpinning the effects of short-term TRF, we investigated skeletal muscle and serum metabolic and transcriptomic profiles from 11 men with overweight/obesity after TRF (8 h day-1) and extended feeding (EXF, 15 h day-1) in a randomised cross-over design (trial registration: ACTRN12617000165381). Here we show that muscle core clock gene expression was similar after both interventions. TRF increases the amplitude of oscillating muscle transcripts, but not muscle or serum metabolites. In muscle, TRF induces rhythmicity of several amino acid transporter genes and metabolites. In serum, lipids are the largest class of periodic metabolites, while the majority of phase-shifted metabolites are amino acid related. In conclusion, short-term TRF in overweight men affects the rhythmicity of serum and muscle metabolites and regulates the rhythmicity of genes controlling amino acid transport, without perturbing core clock gene expression.",
author = "Lundell, {Leonidas S} and Parr, {Evelyn B} and Devlin, {Brooke L} and Ingerslev, {Lars R} and Ali Altınta{\c s} and Shogo Sato and Paolo Sassone-Corsi and Romain Barr{\`e}s and Zierath, {Juleen R} and Hawley, {John A}",
note = "Author correction: https://www.nature.com/articles/s41467-020-19100-5 10.1038/s41467-020-19100-5",
year = "2020",
doi = "10.1038/s41467-020-18412-w",
language = "English",
volume = "11",
journal = "Nature Communications",
issn = "2041-1723",
publisher = "nature publishing group",
number = "1",

}

RIS

TY - JOUR

T1 - Time-restricted feeding alters lipid and amino acid metabolite rhythmicity without perturbing clock gene expression

T2 - [Author Correction]

AU - Lundell, Leonidas S

AU - Parr, Evelyn B

AU - Devlin, Brooke L

AU - Ingerslev, Lars R

AU - Altıntaş, Ali

AU - Sato, Shogo

AU - Sassone-Corsi, Paolo

AU - Barrès, Romain

AU - Zierath, Juleen R

AU - Hawley, John A

N1 - Author correction: https://www.nature.com/articles/s41467-020-19100-5 10.1038/s41467-020-19100-5

PY - 2020

Y1 - 2020

N2 - Time-restricted feeding (TRF) improves metabolism independent of dietary macronutrient composition or energy restriction. To elucidate mechanisms underpinning the effects of short-term TRF, we investigated skeletal muscle and serum metabolic and transcriptomic profiles from 11 men with overweight/obesity after TRF (8 h day-1) and extended feeding (EXF, 15 h day-1) in a randomised cross-over design (trial registration: ACTRN12617000165381). Here we show that muscle core clock gene expression was similar after both interventions. TRF increases the amplitude of oscillating muscle transcripts, but not muscle or serum metabolites. In muscle, TRF induces rhythmicity of several amino acid transporter genes and metabolites. In serum, lipids are the largest class of periodic metabolites, while the majority of phase-shifted metabolites are amino acid related. In conclusion, short-term TRF in overweight men affects the rhythmicity of serum and muscle metabolites and regulates the rhythmicity of genes controlling amino acid transport, without perturbing core clock gene expression.

AB - Time-restricted feeding (TRF) improves metabolism independent of dietary macronutrient composition or energy restriction. To elucidate mechanisms underpinning the effects of short-term TRF, we investigated skeletal muscle and serum metabolic and transcriptomic profiles from 11 men with overweight/obesity after TRF (8 h day-1) and extended feeding (EXF, 15 h day-1) in a randomised cross-over design (trial registration: ACTRN12617000165381). Here we show that muscle core clock gene expression was similar after both interventions. TRF increases the amplitude of oscillating muscle transcripts, but not muscle or serum metabolites. In muscle, TRF induces rhythmicity of several amino acid transporter genes and metabolites. In serum, lipids are the largest class of periodic metabolites, while the majority of phase-shifted metabolites are amino acid related. In conclusion, short-term TRF in overweight men affects the rhythmicity of serum and muscle metabolites and regulates the rhythmicity of genes controlling amino acid transport, without perturbing core clock gene expression.

U2 - 10.1038/s41467-020-18412-w

DO - 10.1038/s41467-020-18412-w

M3 - Journal article

C2 - 32938935

VL - 11

JO - Nature Communications

JF - Nature Communications

SN - 2041-1723

IS - 1

M1 - 4643

ER -

ID: 249102606