DNA methylation in metabolic disorders

Research output: Contribution to journal › Review › Research › peer-review

Standard

DNA methylation in metabolic disorders. / Barres, Romain; Zierath, Juleen R.

In: American Journal of Clinical Nutrition, Vol. 93, No. 4, 01.04.2011, p. 897S-900.

Research output: Contribution to journal › Review › Research › peer-review

Harvard

Barres, R & Zierath, JR 2011, 'DNA methylation in metabolic disorders', American Journal of Clinical Nutrition, vol. 93, no. 4, pp. 897S-900. https://doi.org/10.3945/ajcn.110.001933

APA

Barres, R., & Zierath, J. R. (2011). DNA methylation in metabolic disorders. American Journal of Clinical Nutrition, 93(4), 897S-900. https://doi.org/10.3945/ajcn.110.001933

Vancouver

Barres R, Zierath JR. DNA methylation in metabolic disorders. American Journal of Clinical Nutrition. 2011 Apr 1;93(4):897S-900. https://doi.org/10.3945/ajcn.110.001933

Author

Barres, Romain ; Zierath, Juleen R. / DNA methylation in metabolic disorders. In: American Journal of Clinical Nutrition. 2011 ; Vol. 93, No. 4. pp. 897S-900.

Bibtex

@article{e104ccd620c44a93a3cd0d099145917f,
title = "DNA methylation in metabolic disorders",
abstract = "DNA methylation is a major epigenetic modification that controls gene expression in physiologic and pathologic states. Metabolic diseases such as diabetes and obesity are associated with profound alterations in gene expression that are caused by genetic and environmental factors. Recent reports have provided evidence that environmental factors at all ages could modify DNA methylation in somatic tissues, which suggests that DNA methylation is a more dynamic process than previously appreciated. Because of the importance of lifestyle factors in metabolic disorders, DNA methylation provides a mechanism by which environmental factors, including diet and exercise, can modify genetic predisposition to disease. This article considers the current evidence that defines a role for DNA methylation in metabolic disorders.",
keywords = "DNA Methylation, Diet, Environment, Epigenesis, Genetic, Exercise, Gene Expression, Genetic Predisposition to Disease, Humans, Metabolic Diseases",
author = "Romain Barres and Zierath, {Juleen R}",
year = "2011",
month = apr,
day = "1",
doi = "10.3945/ajcn.110.001933",
language = "English",
volume = "93",
pages = "897S--900",
journal = "American Journal of Clinical Nutrition",
issn = "0002-9165",
publisher = "American Society for Nutrition",
number = "4",

}

RIS

TY - JOUR

T1 - DNA methylation in metabolic disorders

AU - Barres, Romain

AU - Zierath, Juleen R

PY - 2011/4/1

Y1 - 2011/4/1

N2 - DNA methylation is a major epigenetic modification that controls gene expression in physiologic and pathologic states. Metabolic diseases such as diabetes and obesity are associated with profound alterations in gene expression that are caused by genetic and environmental factors. Recent reports have provided evidence that environmental factors at all ages could modify DNA methylation in somatic tissues, which suggests that DNA methylation is a more dynamic process than previously appreciated. Because of the importance of lifestyle factors in metabolic disorders, DNA methylation provides a mechanism by which environmental factors, including diet and exercise, can modify genetic predisposition to disease. This article considers the current evidence that defines a role for DNA methylation in metabolic disorders.

AB - DNA methylation is a major epigenetic modification that controls gene expression in physiologic and pathologic states. Metabolic diseases such as diabetes and obesity are associated with profound alterations in gene expression that are caused by genetic and environmental factors. Recent reports have provided evidence that environmental factors at all ages could modify DNA methylation in somatic tissues, which suggests that DNA methylation is a more dynamic process than previously appreciated. Because of the importance of lifestyle factors in metabolic disorders, DNA methylation provides a mechanism by which environmental factors, including diet and exercise, can modify genetic predisposition to disease. This article considers the current evidence that defines a role for DNA methylation in metabolic disorders.

KW - DNA Methylation

KW - Diet

KW - Environment

KW - Epigenesis, Genetic

KW - Exercise

KW - Gene Expression

KW - Genetic Predisposition to Disease

KW - Humans

KW - Metabolic Diseases

U2 - 10.3945/ajcn.110.001933

DO - 10.3945/ajcn.110.001933

M3 - Review

C2 - 21289222

VL - 93

SP - 897S-900

JO - American Journal of Clinical Nutrition

JF - American Journal of Clinical Nutrition

SN - 0002-9165

IS - 4

ER -

ID: 35090972