Cross-sectional associations between macronutrient intake and chronic kidney disease in a population at high cardiovascular risk

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Cross-sectional associations between macronutrient intake and chronic kidney disease in a population at high cardiovascular risk. / Díaz-López, Andrés; Bulló, Mònica; Basora, Josep; Martínez-González, Miguel Ángel; Guasch-Ferré, Marta; Estruch, Ramon; Wärnberg, Julia; Serra-Majem, Lluís; Arós, Fernando; Lapetra, José; Ros, Emilio; Pintó, Xavier; Covas, María Isabel; Salas-Salvadó, Jordi.

In: Clinical Nutrition, Vol. 32, No. 4, 2013, p. 606-612.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Díaz-López, A, Bulló, M, Basora, J, Martínez-González, MÁ, Guasch-Ferré, M, Estruch, R, Wärnberg, J, Serra-Majem, L, Arós, F, Lapetra, J, Ros, E, Pintó, X, Covas, MI & Salas-Salvadó, J 2013, 'Cross-sectional associations between macronutrient intake and chronic kidney disease in a population at high cardiovascular risk', Clinical Nutrition, vol. 32, no. 4, pp. 606-612. https://doi.org/10.1016/j.clnu.2012.10.013

APA

Díaz-López, A., Bulló, M., Basora, J., Martínez-González, M. Á., Guasch-Ferré, M., Estruch, R., Wärnberg, J., Serra-Majem, L., Arós, F., Lapetra, J., Ros, E., Pintó, X., Covas, M. I., & Salas-Salvadó, J. (2013). Cross-sectional associations between macronutrient intake and chronic kidney disease in a population at high cardiovascular risk. Clinical Nutrition, 32(4), 606-612. https://doi.org/10.1016/j.clnu.2012.10.013

Vancouver

Díaz-López A, Bulló M, Basora J, Martínez-González MÁ, Guasch-Ferré M, Estruch R et al. Cross-sectional associations between macronutrient intake and chronic kidney disease in a population at high cardiovascular risk. Clinical Nutrition. 2013;32(4):606-612. https://doi.org/10.1016/j.clnu.2012.10.013

Author

Díaz-López, Andrés ; Bulló, Mònica ; Basora, Josep ; Martínez-González, Miguel Ángel ; Guasch-Ferré, Marta ; Estruch, Ramon ; Wärnberg, Julia ; Serra-Majem, Lluís ; Arós, Fernando ; Lapetra, José ; Ros, Emilio ; Pintó, Xavier ; Covas, María Isabel ; Salas-Salvadó, Jordi. / Cross-sectional associations between macronutrient intake and chronic kidney disease in a population at high cardiovascular risk. In: Clinical Nutrition. 2013 ; Vol. 32, No. 4. pp. 606-612.

Bibtex

@article{ec28587aba3f4f46beab69933e9650c6,
title = "Cross-sectional associations between macronutrient intake and chronic kidney disease in a population at high cardiovascular risk",
abstract = "BACKGROUND & AIMS: The aim was to examine the associations between macronutrient intake and the prevalence of chronic kidney disease (CKD) or microalbuminuria (MiA) in individuals at high cardiovascular risk.METHODS: Cross-sectional analyses conducted in 2123 nondiabetic individuals from the PREDIMED study. Dietary data were collected using a food-frequency questionnaire. Analysis of covariance was used to assess associations between quartiles of nutrient intake and estimated glomerular filtration rate (eGFR) or urinary albumin-to-creatinine ratio (ACR). The odds ratio (OR) for the presence of CKD or MiA according to quartiles of nutrient intake was assessed by logistic regression models.RESULTS: Individuals in the highest quartile of n-6 polyunsaturated fatty acid (PUFA) intake showed lower average eGFR. Individuals in the top quartile of fiber intake had a decreased risk of CKD [OR: 0.68; 95% CI: 0.48-0.95]. Conversely, subjects in the highest quartile of n-6 PUFA intake showed an increased risk of CKD [OR: 1.44; 95% CI: 1.03-2.01]. No significant associations were found between the intake of other macronutrients and eGFR, urinary ACR or risk of CKD or MiA.CONCLUSIONS: A high fiber intake was associated with a decreased risk of CKD, while a high n-6 PUFA intake was inversely associated with eGFR and directly associated with an increased risk of CKD.",
keywords = "Aged, Aged, 80 and over, Albuminuria/complications, Cardiovascular Diseases/complications, Creatinine/urine, Cross-Sectional Studies, Diet, Dietary Fiber/administration & dosage, Energy Intake, Fatty Acids, Omega-6/administration & dosage, Female, Glomerular Filtration Rate, Humans, Logistic Models, Male, Middle Aged, Multivariate Analysis, Odds Ratio, Prevalence, Renal Insufficiency, Chronic/complications, Risk Factors, Surveys and Questionnaires",
author = "Andr{\'e}s D{\'i}az-L{\'o}pez and M{\`o}nica Bull{\'o} and Josep Basora and Mart{\'i}nez-Gonz{\'a}lez, {Miguel {\'A}ngel} and Marta Guasch-Ferr{\'e} and Ramon Estruch and Julia W{\"a}rnberg and Llu{\'i}s Serra-Majem and Fernando Ar{\'o}s and Jos{\'e} Lapetra and Emilio Ros and Xavier Pint{\'o} and Covas, {Mar{\'i}a Isabel} and Jordi Salas-Salvad{\'o}",
note = "Copyright {\textcopyright} 2012 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved.",
year = "2013",
doi = "10.1016/j.clnu.2012.10.013",
language = "English",
volume = "32",
pages = "606--612",
journal = "Clinical Nutrition",
issn = "0261-5614",
publisher = "Elsevier",
number = "4",

}

RIS

TY - JOUR

T1 - Cross-sectional associations between macronutrient intake and chronic kidney disease in a population at high cardiovascular risk

AU - Díaz-López, Andrés

AU - Bulló, Mònica

AU - Basora, Josep

AU - Martínez-González, Miguel Ángel

AU - Guasch-Ferré, Marta

AU - Estruch, Ramon

AU - Wärnberg, Julia

AU - Serra-Majem, Lluís

AU - Arós, Fernando

AU - Lapetra, José

AU - Ros, Emilio

AU - Pintó, Xavier

AU - Covas, María Isabel

AU - Salas-Salvadó, Jordi

N1 - Copyright © 2012 Elsevier Ltd and European Society for Clinical Nutrition and Metabolism. All rights reserved.

PY - 2013

Y1 - 2013

N2 - BACKGROUND & AIMS: The aim was to examine the associations between macronutrient intake and the prevalence of chronic kidney disease (CKD) or microalbuminuria (MiA) in individuals at high cardiovascular risk.METHODS: Cross-sectional analyses conducted in 2123 nondiabetic individuals from the PREDIMED study. Dietary data were collected using a food-frequency questionnaire. Analysis of covariance was used to assess associations between quartiles of nutrient intake and estimated glomerular filtration rate (eGFR) or urinary albumin-to-creatinine ratio (ACR). The odds ratio (OR) for the presence of CKD or MiA according to quartiles of nutrient intake was assessed by logistic regression models.RESULTS: Individuals in the highest quartile of n-6 polyunsaturated fatty acid (PUFA) intake showed lower average eGFR. Individuals in the top quartile of fiber intake had a decreased risk of CKD [OR: 0.68; 95% CI: 0.48-0.95]. Conversely, subjects in the highest quartile of n-6 PUFA intake showed an increased risk of CKD [OR: 1.44; 95% CI: 1.03-2.01]. No significant associations were found between the intake of other macronutrients and eGFR, urinary ACR or risk of CKD or MiA.CONCLUSIONS: A high fiber intake was associated with a decreased risk of CKD, while a high n-6 PUFA intake was inversely associated with eGFR and directly associated with an increased risk of CKD.

AB - BACKGROUND & AIMS: The aim was to examine the associations between macronutrient intake and the prevalence of chronic kidney disease (CKD) or microalbuminuria (MiA) in individuals at high cardiovascular risk.METHODS: Cross-sectional analyses conducted in 2123 nondiabetic individuals from the PREDIMED study. Dietary data were collected using a food-frequency questionnaire. Analysis of covariance was used to assess associations between quartiles of nutrient intake and estimated glomerular filtration rate (eGFR) or urinary albumin-to-creatinine ratio (ACR). The odds ratio (OR) for the presence of CKD or MiA according to quartiles of nutrient intake was assessed by logistic regression models.RESULTS: Individuals in the highest quartile of n-6 polyunsaturated fatty acid (PUFA) intake showed lower average eGFR. Individuals in the top quartile of fiber intake had a decreased risk of CKD [OR: 0.68; 95% CI: 0.48-0.95]. Conversely, subjects in the highest quartile of n-6 PUFA intake showed an increased risk of CKD [OR: 1.44; 95% CI: 1.03-2.01]. No significant associations were found between the intake of other macronutrients and eGFR, urinary ACR or risk of CKD or MiA.CONCLUSIONS: A high fiber intake was associated with a decreased risk of CKD, while a high n-6 PUFA intake was inversely associated with eGFR and directly associated with an increased risk of CKD.

KW - Aged

KW - Aged, 80 and over

KW - Albuminuria/complications

KW - Cardiovascular Diseases/complications

KW - Creatinine/urine

KW - Cross-Sectional Studies

KW - Diet

KW - Dietary Fiber/administration & dosage

KW - Energy Intake

KW - Fatty Acids, Omega-6/administration & dosage

KW - Female

KW - Glomerular Filtration Rate

KW - Humans

KW - Logistic Models

KW - Male

KW - Middle Aged

KW - Multivariate Analysis

KW - Odds Ratio

KW - Prevalence

KW - Renal Insufficiency, Chronic/complications

KW - Risk Factors

KW - Surveys and Questionnaires

U2 - 10.1016/j.clnu.2012.10.013

DO - 10.1016/j.clnu.2012.10.013

M3 - Journal article

C2 - 23141101

VL - 32

SP - 606

EP - 612

JO - Clinical Nutrition

JF - Clinical Nutrition

SN - 0261-5614

IS - 4

ER -

ID: 351050250