Dietary magnesium intake is inversely associated with mortality in adults at high cardiovascular disease risk

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Dietary magnesium intake is inversely associated with mortality in adults at high cardiovascular disease risk. / Guasch-Ferré, Marta; Bulló, Mònica; Estruch, Ramon; Corella, Dolores; Martínez-González, Miguel A.; Ros, Emilio; Covas, Maribel; Arós, Fernando; Gómez-Gracia, Enrique; Fiol, Miquel; Lapetra, José; Muñoz, Miguel Ángel; Serra-Majem, Lluís; Babio, Nancy; Pintó, Xavier; Lamuela-Raventós, Rosa M.; Ruiz-Gutiérrez, Valentina; Salas-Salvadó, Jordi.

In: Journal of Nutrition, Vol. 144, No. 1, 2014, p. 55-60.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Guasch-Ferré, M, Bulló, M, Estruch, R, Corella, D, Martínez-González, MA, Ros, E, Covas, M, Arós, F, Gómez-Gracia, E, Fiol, M, Lapetra, J, Muñoz, MÁ, Serra-Majem, L, Babio, N, Pintó, X, Lamuela-Raventós, RM, Ruiz-Gutiérrez, V & Salas-Salvadó, J 2014, 'Dietary magnesium intake is inversely associated with mortality in adults at high cardiovascular disease risk', Journal of Nutrition, vol. 144, no. 1, pp. 55-60. https://doi.org/10.3945/jn.113.183012

APA

Guasch-Ferré, M., Bulló, M., Estruch, R., Corella, D., Martínez-González, M. A., Ros, E., Covas, M., Arós, F., Gómez-Gracia, E., Fiol, M., Lapetra, J., Muñoz, M. Á., Serra-Majem, L., Babio, N., Pintó, X., Lamuela-Raventós, R. M., Ruiz-Gutiérrez, V., & Salas-Salvadó, J. (2014). Dietary magnesium intake is inversely associated with mortality in adults at high cardiovascular disease risk. Journal of Nutrition, 144(1), 55-60. https://doi.org/10.3945/jn.113.183012

Vancouver

Guasch-Ferré M, Bulló M, Estruch R, Corella D, Martínez-González MA, Ros E et al. Dietary magnesium intake is inversely associated with mortality in adults at high cardiovascular disease risk. Journal of Nutrition. 2014;144(1):55-60. https://doi.org/10.3945/jn.113.183012

Author

Guasch-Ferré, Marta ; Bulló, Mònica ; Estruch, Ramon ; Corella, Dolores ; Martínez-González, Miguel A. ; Ros, Emilio ; Covas, Maribel ; Arós, Fernando ; Gómez-Gracia, Enrique ; Fiol, Miquel ; Lapetra, José ; Muñoz, Miguel Ángel ; Serra-Majem, Lluís ; Babio, Nancy ; Pintó, Xavier ; Lamuela-Raventós, Rosa M. ; Ruiz-Gutiérrez, Valentina ; Salas-Salvadó, Jordi. / Dietary magnesium intake is inversely associated with mortality in adults at high cardiovascular disease risk. In: Journal of Nutrition. 2014 ; Vol. 144, No. 1. pp. 55-60.

Bibtex

@article{3c10bd0c8ff547038d6511c7ecd2308d,
title = "Dietary magnesium intake is inversely associated with mortality in adults at high cardiovascular disease risk",
abstract = "The relation between dietary magnesium intake and cardiovascular disease (CVD) or mortality was evaluated in several prospective studies, but few of them have assessed the risk of all-cause mortality, which has never been evaluated in Mediterranean adults at high cardiovascular risk. The aim of this study was to assess the association between magnesium intake and CVD and mortality risk in a Mediterranean population at high cardiovascular risk with high averagemagnesium intake. The present study included 7216 men and women aged 55-80 y fromthe PREDIMED (Prevenc{\'i}on con Dieta Mediter{\'r}anea) study, a randomized clinical trial. Participants were assigned to 1 of 2 Mediterranean diets (supplemented with nuts or olive oil) or to a control diet (advice on a low-fat diet). Mortality was ascertained by linkage to the National Death Index and medical records. We fitted multivariable-adjusted Cox regressions to assess associations between baseline energy-adjusted tertiles of magnesium intake and relative risk of CVD and mortality. Multivariable analyses with generalized estimating equation models were used to assess the associations between yearly repeated measurements of magnesium intake and mortality. After a median follow-up of 4.8 y, 323 total deaths, 81 cardiovascular deaths, 130 cancer deaths, and 277 cardiovascular events occurred. Energy-adjusted baseline magnesium intake was inversely associated with cardiovascular, cancer, and all-cause mortality. Compared with lower consumers, individuals in the highest tertile of magnesium intake had a 34% reduction in mortality risk (HR: 0.66; 95% CI: 0.45, 0.95; P < 0.01). Dietary magnesium intake was inversely associated with mortality risk in Mediterranean individuals at high risk of CVD.",
author = "Marta Guasch-Ferr{\'e} and M{\`o}nica Bull{\'o} and Ramon Estruch and Dolores Corella and Mart{\'i}nez-Gonz{\'a}lez, {Miguel A.} and Emilio Ros and Maribel Covas and Fernando Ar{\'o}s and Enrique G{\'o}mez-Gracia and Miquel Fiol and Jos{\'e} Lapetra and Mu{\~n}oz, {Miguel {\'A}ngel} and Llu{\'i}s Serra-Majem and Nancy Babio and Xavier Pint{\'o} and Lamuela-Ravent{\'o}s, {Rosa M.} and Valentina Ruiz-Guti{\'e}rrez and Jordi Salas-Salvad{\'o}",
year = "2014",
doi = "10.3945/jn.113.183012",
language = "English",
volume = "144",
pages = "55--60",
journal = "Journal of Nutrition",
issn = "0022-3166",
publisher = "American Society for Nutrition",
number = "1",

}

RIS

TY - JOUR

T1 - Dietary magnesium intake is inversely associated with mortality in adults at high cardiovascular disease risk

AU - Guasch-Ferré, Marta

AU - Bulló, Mònica

AU - Estruch, Ramon

AU - Corella, Dolores

AU - Martínez-González, Miguel A.

AU - Ros, Emilio

AU - Covas, Maribel

AU - Arós, Fernando

AU - Gómez-Gracia, Enrique

AU - Fiol, Miquel

AU - Lapetra, José

AU - Muñoz, Miguel Ángel

AU - Serra-Majem, Lluís

AU - Babio, Nancy

AU - Pintó, Xavier

AU - Lamuela-Raventós, Rosa M.

AU - Ruiz-Gutiérrez, Valentina

AU - Salas-Salvadó, Jordi

PY - 2014

Y1 - 2014

N2 - The relation between dietary magnesium intake and cardiovascular disease (CVD) or mortality was evaluated in several prospective studies, but few of them have assessed the risk of all-cause mortality, which has never been evaluated in Mediterranean adults at high cardiovascular risk. The aim of this study was to assess the association between magnesium intake and CVD and mortality risk in a Mediterranean population at high cardiovascular risk with high averagemagnesium intake. The present study included 7216 men and women aged 55-80 y fromthe PREDIMED (Prevencíon con Dieta Mediterŕanea) study, a randomized clinical trial. Participants were assigned to 1 of 2 Mediterranean diets (supplemented with nuts or olive oil) or to a control diet (advice on a low-fat diet). Mortality was ascertained by linkage to the National Death Index and medical records. We fitted multivariable-adjusted Cox regressions to assess associations between baseline energy-adjusted tertiles of magnesium intake and relative risk of CVD and mortality. Multivariable analyses with generalized estimating equation models were used to assess the associations between yearly repeated measurements of magnesium intake and mortality. After a median follow-up of 4.8 y, 323 total deaths, 81 cardiovascular deaths, 130 cancer deaths, and 277 cardiovascular events occurred. Energy-adjusted baseline magnesium intake was inversely associated with cardiovascular, cancer, and all-cause mortality. Compared with lower consumers, individuals in the highest tertile of magnesium intake had a 34% reduction in mortality risk (HR: 0.66; 95% CI: 0.45, 0.95; P < 0.01). Dietary magnesium intake was inversely associated with mortality risk in Mediterranean individuals at high risk of CVD.

AB - The relation between dietary magnesium intake and cardiovascular disease (CVD) or mortality was evaluated in several prospective studies, but few of them have assessed the risk of all-cause mortality, which has never been evaluated in Mediterranean adults at high cardiovascular risk. The aim of this study was to assess the association between magnesium intake and CVD and mortality risk in a Mediterranean population at high cardiovascular risk with high averagemagnesium intake. The present study included 7216 men and women aged 55-80 y fromthe PREDIMED (Prevencíon con Dieta Mediterŕanea) study, a randomized clinical trial. Participants were assigned to 1 of 2 Mediterranean diets (supplemented with nuts or olive oil) or to a control diet (advice on a low-fat diet). Mortality was ascertained by linkage to the National Death Index and medical records. We fitted multivariable-adjusted Cox regressions to assess associations between baseline energy-adjusted tertiles of magnesium intake and relative risk of CVD and mortality. Multivariable analyses with generalized estimating equation models were used to assess the associations between yearly repeated measurements of magnesium intake and mortality. After a median follow-up of 4.8 y, 323 total deaths, 81 cardiovascular deaths, 130 cancer deaths, and 277 cardiovascular events occurred. Energy-adjusted baseline magnesium intake was inversely associated with cardiovascular, cancer, and all-cause mortality. Compared with lower consumers, individuals in the highest tertile of magnesium intake had a 34% reduction in mortality risk (HR: 0.66; 95% CI: 0.45, 0.95; P < 0.01). Dietary magnesium intake was inversely associated with mortality risk in Mediterranean individuals at high risk of CVD.

U2 - 10.3945/jn.113.183012

DO - 10.3945/jn.113.183012

M3 - Journal article

AN - SCOPUS:84890961713

VL - 144

SP - 55

EP - 60

JO - Journal of Nutrition

JF - Journal of Nutrition

SN - 0022-3166

IS - 1

ER -

ID: 358645844