Jens Juul Holst

Jens Juul Holst

Professor

ORCID: 0000-0001-6853-3805

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  1. Published

    The impact of short chain fatty acids on GLP-1 and PYY secretion from the isolated perfused rat colon

    Christiansen, Charlotte Bayer, Gabe, M. B. N., Svendsen, B., Dragsted, Lars Ove, Rosenkilde, Mette & Holst, Jens Juul, 2018, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 315, 1, p. G53-G65 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    The importance of endogenously secreted GLP-1 and GIP for postprandial glucose tolerance and β-cell function after Roux-en-Y gastric bypass and sleeve gastrectomy surgery

    Hindsø, M., Hedbäck, N., Svane, M. S., Møller, A., Martinussen, C., Jørgensen, N. B., Dirksen, C., Gasbjerg, Lærke Smidt, Kristiansen, V. B., Hartmann, Bolette, Rosenkilde, Mette, Holst, Jens Juul, Madsbad, Sten & Bojsen-Møller, K. N., 2023, In: Diabetes. 72, 3, p. 336–347

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    The importance of glucose-dependent insulinotropic polypeptide receptor activation for the effects of tirzepatide

    Gasbjerg, Lærke Smidt, Rosenkilde, Mette, Meier, J. J., Holst, Jens Juul & Knop, Filip Krag, 2023, In: Diabetes, Obesity and Metabolism. 25, 11, p. 3079-3092

    Research output: Contribution to journal › Review › Research › peer-review

  4. Published

    The imprinted gene Delta like non-canonical notch ligand 1 (Dlk1) associates with obesity and triggers insulin resistance through inhibition of skeletal muscle glucose uptake

    Jensen, C. H., Kosmina, R., Rydén, M., Baun, C., Hvidsten, S., Andersen, M. S., Christensen, L. L., Gastaldelli, A., Marraccini, P., Arner, P., Jørgensen, C. D., Laborda, J., Holst, Jens Juul & Andersen, D. C., 2019, In: EBioMedicine. 46, p. 368-380 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    The incretin approach for diabetes treatment: modulation of islet hormone release by GLP-1 agonism.

    Holst, Jens Juul & Ørskov, Cathrine, 2004, In: Diabetes. 53 Suppl 3, p. S197-204

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    The incretin effect does not differ in trained and untrained, young, healthy men

    Lund, M. T., Dalby, S., Hartmann, Bolette, Helge, Jørn Wulff, Holst, Jens Juul & Dela, Flemming, Mar 2014, In: Acta Physiologica. 210, 3, p. 565-72 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    The incretin effect in patients with maturity onset diabetes of the young

    Ostoft, S. H., Bagger, J. I., Hansen, T., Pedersen, O., Holst, Jens Juul, Knop, Filip Krag & Vilsboll, T., 2012, In: Diabetologia. 55, p. S144-S144

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    The incretin enhancer vildagliptin, a dipeptidyl peptidase-IV inhibitor, improves model-assessed -cell function in patients with type 2 diabetes

    Mari, A., Sallas, W. M., He, Y. L., Watson, C., Ligueros-Saylan, M., Dunning, B. E., Deacon, Carolyn F., Holst, Jens Juul & Foley, J. E., 2005, In: Journal of Clinical Endocrinology and Metabolism. 90, p. 4888-4894

    Research output: Contribution to journal › Journal article › Research

  9. Published

    The incretin system and its role in type 2 diabetes mellitus

    Holst, Jens Juul, Vilsbøll, Tina & Deacon, Carolyn F., 2008, In: Molecular and Cellular Endocrinology. 297, 1-2, p. 127-136 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    The incretin system in healthy humans: The role of GIP and GLP-1

    Holst, Jens Juul, 2019, In: Metabolism. 96, p. 46-55

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    The incretin/glucagon system as a target for pharmacotherapy of obesity

    Del Prato, S., Gallwitz, B., Holst, Jens Juul & Meier, J. J., 2022, In: Obesity Reviews. 23, 2, 13 p., e13372.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    The influence of GLP-1 on glucose-induced insulin secretion: effect on ß-cells sensitivity in type 2 and non-diabetic subjects

    Kjems, L. L., Holst, Jens Juul, Vølund, A. A. & Madsbad, S., 2003, In: Diabetes. 52, p. 380-386

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    The influence of GLP-1 on glucose-stimulated insulin secretion: effects on beta-cell sensitivity in type 2 and nondiabetic subjects

    Kjems, L. L., Holst, Jens Juul, Vølund, A. & Madsbad, Sten, Feb 2003, In: Diabetes. 52, 2, p. 380-6 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    The influence of glucagon on postprandial hyperglycaemia in children 5 years after onset of type 1 diabetes

    Fredheim, S., Andersen, M. M., Pörksen, S., Nielsen, L. B., Pipper, C., Hansen, L., Holst, Jens Juul, Thomsen, J., Johannesen, Jesper, Mortensen, H. B. & Svensson, Jannet, 2015, In: Diabetologia. 58, 4, p. 828-34 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    The influence of nutrients, biliary-pancreatic secretions, and systemic trophic hormones on intestinal adaptation in a Roux-en-Y bypass model

    Taqi, E., Wallace, L. E., de Heuvel, E., Chelikani, P. K., Zheng, H., Berthoud, H., Holst, Jens Juul & Sigalet, D. L., 1 May 2010, In: European Journal of Pediatric Surgery. Supplement. 45, 5, p. 987-95 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    The inhibitory effect of glucagon-like peptide-1 (7-36) amide on antral motility is antagonized by its N-terminally truncated primary metabolite GLP-1 (9-36) amide.

    Wettergren, A., Wojdemann, M. & Holst, Jens Juul, 1998, In: Peptides. 19, p. 877-882

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    The inhibitory effect of glucagon-like peptide-1 (GLP-1) 7-36 amide on gastric acid secretion in humans depends on an intact vagal innervation.

    Wettergren, A., Wøjdemann, M., Meisner, S., Stadil, F. & Holst, Jens Juul, 1997, In: Gut. 40, p. 597-601

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    The insulinogenic effect of whey protein is partially mediated by a direct effect of amino acids and GIP on β-cells

    Salehi, A., Gunnerud, U., Muhammed, S. J., Ostman, E., Holst, Jens Juul, Björck, I. & Rorsman, P., 2012, In: Nutrition & Metabolism. 9, 1, p. 48

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    The insulinotropic effect of GIP is impaired in patients with chronic pancreatitis and secondary diabetes mellitus as compared to patients with chronic pancreatitis and normal glucose tolerance.

    Knop, F. K., Vilsbøll, Tina, Højberg, P. V., Larsen, S., Madsbad, Sten, Holst, Jens Juul & Krarup, T., 2007, In: Regulatory Peptides. 144, 1-3, p. 123-30 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    The insulinotropic effect of exogenous GLP-1 is not affected by acute vagotomy in anaesthetized pigs

    Veedfald, Simon, Hansen, M., Christensen, L. W., Larsen, S. A. H., Hjøllund, K. R., Plamboeck, A., Hartmann, Bolette, Deacon, Carolyn F. & Holst, Jens Juul, 30 Mar 2016, In: Experimental Physiology. 101, 7, p. 895-912 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    The interleukin-1 receptor antagonist anakinra improves first-phase insulin secretion and insulinogenic index in subjects with impaired glucose tolerance

    van Poppel, P. C. M., van Asseldonk, E. J. P., Holst, Jens Juul, Vilsbøll, Tina, Netea, M. G. & Tack, C. J., Dec 2014, In: Diabetes, Obesity and Metabolism. 16, 12, p. 1269-73 5 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  22. Published

    The intestinal distribution pattern of appetite- and glucose regulatory peptides in mice, rats and pigs

    Albrechtsen, Nicolai Jacob Wewer, Kuhre, Rune Ehrenreich, Toräng, S. & Holst, Jens Juul, 2 Feb 2016, In: BMC Research Notes. 9, 1, p. 1-6 6 p., 60.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    The intestinotrophic peptide, GLP-2, counteracts the gastrointestinal atrophy in mice induced by the epidermal growth factor receptor inhibitor, erlotinib, and cisplatin

    Rasmussen, A. R., Viby, N., Hare, K. J., Hartmann, Bolette, Thim, L., Holst, Jens Juul & Poulsen, Steen Seier, 1 Oct 2010, In: Digestive Diseases and Sciences. 55, 10, p. 2785-96 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    The intestinotrophic peptide, glp-2, counteracts intestinal atrophy in mice induced by the epidermal growth factor receptor inhibitor, gefitinib.

    Hare, K. J., Hartmann, B., Kissow, Hannelouise, Holst, Jens Juul & Poulsen, Steen Seier, 2007, In: Clinical Cancer Research. 13, 17, p. 5170-5 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    The liver-alpha cell axis and type 2 diabetes

    Albrechtsen, Nicolai Jacob Wewer, Pedersen, Jens, Galsgaard, Katrine Douglas, Winther-Sørensen, Marie, Suppli, M. P., Janah, L., Gromada, J., Vilstrup, H., Knop, Filip Krag & Holst, Jens Juul, 2019, In: Endocrine Reviews. 40, 5, p. 1353-1366

    Research output: Contribution to journal › Review › Research › peer-review

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