Jens Juul Holst
Professor
Endocrinology and Metabolism
Blegdamsvej 3
2200 København N.
- 2004
- Published
Plasma GLP-2 levels and intestinal markers in the juvenile pig during intestinal adaptation: effects of different diet regimens
Paris, M. C. J., Fuller, P. J., Taylor, R. G., Nagy, E., Sourial, M., Catto-Smith, T., Hartmann, B., Holst, Jens Juul & Bines, J. E., 2004, In: Dig. Dis. Sci.. 49, p. 1688-1695Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prandial subcutaneous injections of glucagons-like peptide- 1 cause weight loss in obese human subjects
Näslund, E., King, N., Mansten, S., Adner, N., Holst, Jens Juul, Gutniak, M. & Hellström, P., 2004, In: Br.J.Nutr.. 91, p. 439-446Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reduction of beta cell mass: partial insulin secretory compensation from the residual beta cell population in the nicotinamide-streptozotocin Göttingen minipig after oral glucose in vivo and in the perfused pancreas
Larsen, M. O., Rolin, B., Gotfredsen, C. F., Carr, R. D. & Holst, Jens Juul, 2004, In: Diabetologia. 47, p. 1873-1878Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reduction of nocturnal rise in bone resorption by subcutaneous GLP-2.
Henriksen, D. B., Alexandersen, P., Byrjalsen, I., Hartmann, B., Bone, H. G., Christiansen, C. & Holst, Jens Juul, 2004, In: Bone. 34, 1, p. 140-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Role of incretin hormones in the regulation of insulin secretion in diabetic and nondiabetic humans.
Holst, Jens Juul & Gromada, J., 2004, In: American Journal of Physiology: Endocrinology and Metabolism. 287, 2, p. E199-206Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Secretion of incretin hormones (GIP and GLP-1) and incretin effect after oral glucose in first-degree relatives of patients with type 2 diabetes.
Nauck, M. A., El-Ouaghlidi, A., Gabrys, B., Hücking, K., Holst, Jens Juul, Deacon, Carolyn F., Gallwitz, B., Schmidt, W. E. & Meier, J. J., 2004, In: Regulatory Peptides. 122, 3, p. 209-17 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Secretion, degradation, and elimination of glucagon-like peptide 1 and gastric inhibitory polypeptide in patients with chronic renal insufficiency and healthy control subjects.
Meier, J. J., Nauck, M. A., Kranz, D., Holst, Jens Juul, Deacon, Carolyn F., Gaeckler, D., Schmidt, W. E. & Gallwitz, B., 2004, In: Diabetes. 53, 3, p. 654-62 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Similar gastric emptying but greater gastric secretion and GIP release after the ingestion of peptide hydrolysates in man
Calbet, J. A. L. & Holst, Jens Juul, 2004, In: Eur J Nutrition. 43, p. 127-139Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Stimulation of insulin secretion by intravenous bolus injection and continuous infusion of gastric inhibitory polypeptide in patients with type 2 diabetes and healthy control subjects.
Meier, J. J., Gallwitz, B., Kask, B., Deacon, Carolyn F., Holst, Jens Juul, Schmidt, W. E. & Nauck, M. A., 2004, In: Diabetes. 53 Suppl 3, p. S220-4Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Supplementation of total parenteral nutrition with butyrate acutely increases structural aspects of intestinal adaptation following and 80% jejunoileal resection in neonatal pigs
Bartholome, A. L., Albin, D. M., Baker, D. H., Holst, Jens Juul & Tappenden, K. A., 2004, In: J Parenter Enteral Nutr. 28, p. 210-223Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The incretin approach for diabetes treatment: modulation of islet hormone release by GLP-1 agonism.
Holst, Jens Juul & Ørskov, Cathrine, 2004, In: Diabetes. 53 Suppl 3, p. S197-204Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The ¤use of glycaemic index tables to predict glycaemic index of composite breakfast meals
Flint, A., Møller, B. K., Raben, Anne, Pedersen, D., Tetens, I., Holst, Jens Juul & Astrup, A., 2004, In: British Journal of Nutrition. 91, 6, p. 979-989 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Treatment of type 2 diabetes mellitus with agonists of the GLP-1 receptor or DPP-IV inhibitors.
Holst, Jens Juul, 2004, In: Expert Opinion on Emerging Drugs. 9, 1, p. 155-66 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2003
- Published
Role of gastrointestinal hormones in postprandial reduction of bone resorption
Henriksen, D. B., Alexandersen, P., Bjarnason, N. H., Vilsbøll, Tina, Hartmann, B., Henriksen, E. E. G., Byrjalsen, I., Krarup, T., Holst, Jens Juul & Christiansen, C., 1 Dec 2003, In: J Bone Miner Res. 18, 12, p. 2180-2190 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Peripheral administration of GLP-2 to humans has no effect on gastric emptying or satiety
Schmidt, P. T., Näslund, E., Grybäck, P., Jacobsson, H., Hartmann, Bolette, Holst, Jens Juul & Hellström, P. M., 15 Nov 2003, In: Regulatory Peptides. 116, 1-3, p. 21-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Small-intestinal dysfunction accompanies the complex endocrinopathy of human proprotein convertase 1 deficiency
Jackson, R. S., Creemers, J. W. M., Farooqi, I. S., Raffin-Sanson, M-L., Varro, A., Dockray, G. J., Holst, J. J., Brubaker, P. L., Corvol, P., Polonsky, K. S., Ostrega, D., Becker, K. L., Bertagna, X., Hutton, J. C., White, A., Dattani, M. T., Hussain, K., Middleton, S. J., Nicole, T. M., Milla, P. J. & 2 others, , Nov 2003, In: The Journal of Clinical Investigation. 112, 10, p. 1550-60 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structural differences between rye and wheat breads but not total fiber content may explain the lower postprandial insulin response to rye bread
Juntunen, K. S., Laaksonen, D. E., Autio, K., Niskanen, L. K., Holst, Jens Juul, Savolainen, K. E., Liukkonen, K., Poutanen, K. S. & Mykkänen, H. M., Nov 2003, In: Uden navn. 78, 5, p. 957-64 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of GLP-1 effects on beta-cell function after meal ingestion in humans
Ahrén, B., Holst, Jens Juul & Mari, A., Oct 2003, In: Diabetes Care. Supplement. 26, 10, p. 2860-4 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Absence of a memory effect for the insulinotropic action of glucagon-like peptide 1 (GLP-1) in healthy volunteers
Meier, S., Hücking, K., Ritzel, R., Holst, Jens Juul, Schmiegel, W. H. & Nauck, M. A., Sep 2003, In: Hormone and Metabolic Research. Supplement. 35, 9, p. 551-6 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nitric oxide has tonic inhibitory effect, but is not involved in the vagal control or VIP effects on motility of the porcine antrum
Schmidt, P. T., Ørskov, Cathrine, Rasmussen, T. N. & Holst, Jens Juul, Sep 2003, In: Scandinavian Journal of Gastroenterology. 38, 9, p. 955-61 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Both GLP-1 and GIP are insulinotropic at basal and postprandial glucose levels and contribute nearly equally to the incretin effect of a meal in healthy subjects
Vilsbøll, T., Krarup, T., Madsbad, Sten & Holst, Jens Juul, 15 Jul 2003, In: Regulatory Peptides. 114, 2-3, p. 115-21 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-2-mediated up-regulation of intestinal blood flow and glucose uptake is nitric oxide-dependent in TPN-fed piglets 1
Guan, X., Stoll, B., Lu, X., Tappenden, K. A., Holst, Jens Juul, Hartmann, Bolette & Burrin, D. G., Jul 2003, In: Gastroenterology. 125, 1, p. 136-47 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gastric inhibitory polypeptide (GIP) dose-dependently stimulates glucagon secretion in healthy human subjects at euglycaemia
Meier, J. J., Gallwitz, B., Siepmann, N., Holst, Jens Juul, Deacon, Carolyn F., Schmidt, W. E. & Nauck, M. A., Jun 2003, In: Diabetologia. 46, 6, p. 798-801 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Incretin secretion in relation to meal size and body weight in healthy subjects and people with type 1 and type 2 diabetes mellitus
Vilsbøll, T., Krarup, T., Sonne, J., Madsbad, Sten, Vølund, A., Juul, A. G. & Holst, Jens Juul, Jun 2003, In: The Journal of clinical endocrinology and metabolism. 88, 6, p. 2706-13 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Insulin secretion and cellular glucose metabolism after prolonged low-grade intralipid infusion in young men
Jensen, C. B., Storgaard, H., Holst, Jens Juul, Dela, Flemming, Madsbad, Sten & Vaag, Allan, Jun 2003, In: The Journal of clinical endocrinology and metabolism. 88, 6, p. 2775-83 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Introduction of enteral food increases plasma GLP-2 and decreases GLP-2 receptor mRNA abundance during pig development
Petersen, Y. M., Hartmann, Bolette, Holst, Jens Juul, Le Huerou-Luron, I., Bjørnvad, Charlotte Reinhard & Sangild, Per Torp, Jun 2003, In: Journal of Nutrition. 133, 6, p. 1781-6 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Normalization of glucose concentrations and deceleration of gastric emptying after solid meals during intravenous glucagon-like peptide 1 in patients with type 2 diabetes
Meier, J. J., Gallwitz, B., Salmen, S., Goetze, O., Holst, Jens Juul, Schmidt, W. E. & Nauck, M. A., Jun 2003, In: The Journal of clinical endocrinology and metabolism. 88, 6, p. 2719-25 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
No effect of physiological concentrations of glucagon-like peptide-2 on appetite and energy intake in normal weight subjects
Sørensen, L. B., Flint, A., Raben, Anne, Hartmann, Bolette, Holst, Jens Juul & Astrup, A., Apr 2003, In: International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity. 27, 4, p. 450-6 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Role of luminal nutrients and endogenous GLP-2 in intestinal adaptation to mid-small bowel resection
Dahly, E. M., Gillingham, M. B., Guo, Z., Murali, S. G., Nelson, D. W., Holst, Jens Juul & Ney, D. M., Apr 2003, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 284, 4, p. G670-82Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cocaine- and amphetamine-regulated transcript is present in hypothalamic neuroendocrine neurones and is released to the hypothalamic-pituitary portal circuit
Larsen, P. J., Seier, V., Fink-Jensen, Anders, Holst, Jens Juul, Warberg, J. & Vrang, N., Mar 2003, In: Journal of Neuroendocrinology. 15, 3, p. 219-26 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differential effects of saturated and monounsaturated fats on postprandial lipemia and glucagon-like peptide 1 responses in patients with type 2 diabetes
Thomsen, C., Storm, H., Holst, Jens Juul & Hermansen, K., Mar 2003, In: Uden navn. 77, 3, p. 605-11 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The influence of GLP-1 on glucose-stimulated insulin secretion: effects on beta-cell sensitivity in type 2 and nondiabetic subjects
Kjems, L. L., Holst, Jens Juul, Vølund, A. & Madsbad, Sten, Feb 2003, In: Diabetes. 52, 2, p. 380-6 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Similar elimination rates of glucagon-like peptide-1 in obese type 2 diabetic patients and healthy subjects
Vilsbøll, T., Agersø, H., Krarup, T. & Holst, Jens Juul, Jan 2003, In: The Journal of clinical endocrinology and metabolism. 88, 1, p. 220-4 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Absence of a memory effect for the insulinotropic action of glucagon-like peptide 1(GLP-1) in healthy volunteers
Meier, S., Hücking, K., Ritzelt, R., Holst, Jens Juul, Schmiegel, W. H. & Nauck, M. A., 2003, In: Horm Metab Res. 35, p. 551-556Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of GLP-1 effects on beta cell function after meal ingestion in humans
Ahren, B., Holst, Jens Juul & Mari, A., 2003, In: Diabetes Care. 26, p. 2860-2864Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Circulating leptin and thyroid dysfunction.
Zimmermann-Belsing, T., Brabant, G., Holst, Jens Juul & Feldt-Rasmussen, Ulla, 2003, In: European Journal of Endocrinology. 149, 4, p. 257-71 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cocaine and amphetamine-regulated transcript (CART) is present in hypothalamic neuroendocrine neurons and is related to the hypothalamo-pituitary portal circuit
Larsen, P. J., Seier, V., Fink-Jensen, A., Holst, Jens Juul, Warberg, J. & Vrang, N., 2003, In: Journal of Neuroendocrinology. 15, p. 219-226Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Colonic fermentation influences lower esophageal sphincter function in gastroesophageal reflux disease.
Piche, T., des Varannes, S. B., Sacher-Huvelin, S., Holst, Jens Juul, Cuber, J. C. & Galmiche, J. P., 2003, In: Gastroenterology. 124, 4, p. 894-902 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparisons of leptin, incretins and body composition in obese and lean patients with hypopituitarism and healthy individuals
Mersebach, H., Svendsen, Ole Lander, Holst, Jens Juul, Astrup, A. & Feldt-Rasmussen, Ulla, 2003, In: Clinical Endocrinology. 58, 1, p. 65-71 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differential effects of saturated and monounsaturated fat on postprandial lipemia and incretin responses in type 2 diabetic subjects
Thomsen, C., Storm, H., Holst, Jens Juul & Hermansen, K., 2003, In: Am. J. Clin. Nutr.. 77, p. 605-611Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differential regional metabolism of glucagon in anesthetized pigs.
Deacon, Carolyn F., Kelstrup, M., Trebbien, R., Klarskov, L., Olesen, M. & Holst, Jens Juul, 2003, In: American Journal of Physiology: Endocrinology and Metabolism. 285, 3, p. E552-60Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Does overnight normalization of plasma glucose by insulin infusion affect assessment of glucose metabolism in type 2 diabetes
Staehr, P., Højlund, K., Hother-Nielsen, O., Holst, Jens Juul & Beck-Nielsen, H., 2003, In: Diabetic Medicine. 20, p. 816-822Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of GLP-2 treatment and antibiotics on gut structure and function during pig weanling diarrhea
Nielsen, T. T., Sangild, Per Torp, Elnif, J., Sorensen, K., Leser, T., Holst, Jens Juul, Hartmann, B., Jensen, B. B. & Hedemann, M. S., 2003, Ikke angivet. R.O. Ball (ed.). 2 ed. University of Alberta Press, p. 161-163 3 p.Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research
- Published
Effects of free fatty acids per se on glucose production, gluconeogenesis, and glycogenolysis.
Staehr, P., Hother-Nielsen, O., Landau, B. R., Chandramouli, V., Holst, Jens Juul & Beck-Nielsen, H., 2003, In: Diabetes. 52, 2, p. 260-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Et æble om dagen
Larsen, P. J., Holst, Jens Juul & Astrup, A., 2003, In: Politiken. 29, 2 p.Research output: Contribution to journal › Contribution to newspaper - Feature article › Communication
- Published
Exogenous GLP-2 has only marginal effects on weaning-induced intestinal adaption in piglets
le Huërou-Luron, I., Petersen, Y. M., Hartmann, B., Holst, Jens Juul & Sangild, Per Torp, 2003, Ikke angivet. R.O. Ball (ed.). 2 ed. University of Alberta Press, p. 164-166 3 p.Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research
- Published
Functional and immunohistochemical evaluation of porcine neonatal islet-like cell clusters.
Nielsen, T. B., Yderstraede, K. B., Schrøder, H. D., Holst, Jens Juul, Brusgaard, K. & Beck-Nielsen, H., 2003, In: Cell Transplantation. 12, 1, p. 13-25 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-1 and GIP are colocalized in a subset of endocrine cells in the small intestine
Mortensen, K., Christensen, L. L., Holst, Jens Juul & Ørskov, Cathrine, 2003, In: Regulatory Peptides. 114, 2-3, p. 189-96 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-2 mediated up-regulation of intestinal blood flow and glucose uptake is nitric oxide-dependent in TNP-fed piglets
Guan, X., Stoll, B., Lu, X., Tappenden, K., Holst, Jens Juul, Hartmann, B. & Burrin, D. G., 2003, In: Today in Medicine. Gastroenterology. 125, p. 136-147Research output: Contribution to journal › Journal article › Research
- Published
Gastric inhibitory polypeptide (GIP) does not inhibit gastric emptying in man
Meier, J. M., Goetze, O., Anstipp, J., Hagemann, D., Holst, Jens Juul, Schmidt, W. E., Gallwitz, B. & Nauck, M. A., 2003, In: Am. J. Physiol.. 16, p. E621-E625Research output: Contribution to journal › Journal article › Research › peer-review
ID: 4207
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Meal induced gut hormone secretion is altered in aerobically trained compared to sedentary young healthy males
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Copenhagen study of overweight patients with coronary artery disease undergoing low energy diet or interval training: the randomized CUT-IT trial protocol
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Whole grain-rich diet reduces body weight and systemic low-grade inflammation without inducing major changes of the gut microbiome: a randomised cross-over trial
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