Jens Juul Holst

Jens Juul Holst

Professor


  1. 1999
  2. Published

    Increased intensity of physical activity stimulates subsequent fat intake

    Klausen, B., Toubro, S., Ranneries, C., Rehfeld, J. F., Holst, Jens Juul, Christensen, N. J. & Astrup, A., 1999, In: International Journal of Obesity. 23, p. 1282-1287

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Inhibition of dipeptidyl peptidase IV with NVP DPP728 increases plasma GLP-1 (7-36amide) concentrations and improves oral glucose tolerance in obese Zucker rats

    Balkan, B., Kwasnik, L., Miserendino, R., Holst, Jens Juul & Lie, X., 1999, In: Diabetologia. 42, p. 1324-1331

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Inhibition of shamfeeding stimulated human gastric acid secretion by glucagon-like peptide-2

    Wøjdemann, M., Wettergren, A., Hartmann, B., Hilsted, L. M. & Holst, Jens Juul, 1999, In: J. Clin. Endocrinol. Metab.. 84, p. 2513-2517

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Octreotide suppresses the incretin GLP-1 in patients with acromegally, clinically nonfunctioning pituitary tumours and in healthy subjects

    Plöckinger, U., Holst, Jens Juul, Messerschmidt, D., Hopfenmüller, W. & Quabbe, H. J., 1999, In: European Journal of Endocrinology. 140, p. 538-544

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Proglucagon cleavage profile in canine L-cells expressing endogenous PC-1/3 and PC-2

    Damholt, A. B., Buchan, A. M. J., Holst, Jens Juul & Kofod, H., 1999, In: Endokrinologiya. 140, p. 4800-4808

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Selectivity of prandial glucose regulators: nateglinide, but not repaglinide, accelerates exocytosis in rat pancreatic A-cells

    Bokvist, K., Høy, M., Buschard, K., Holst, Jens Juul, Thomsen, M. K. & Gromada, J. L., 1999, In: Eur. J. Pharmacol.. 386, p. 105-111

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Tachykinins stimulate acid and pepsinogen secretion in the isolated perfused porcine stomach

    Schmidt, P. T., Rasmussen, T. N. & Holst, Jens Juul, 1999, In: Acta Physiologica (Print Edition). 166, p. 335-340

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Tachykinins stimulate the release of peptide hormones (glucagon-like peptide-1), and paracrine - (somatostatin) and neurotransmitters (vasoactive intestinal polypeptide) from porcine ileum through NK-1 receptors

    Schmidt, P. T., Rickelt, L. F. & Holst, Jens Juul, 1999, In: Digestive Diseases and Sciences. 44, p. 1273-1281

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    The arcuate nucleus is pivotal in mediating the anorectic effects of centrally administered leptin

    Tang-Christensen, M., Holst, Jens Juul, Hartmann, B. & Vrang, N., 1999, In: NeuroReport. 10, p. 1183-1187

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    The hypothalamic satiety peptide CART is expressed in anorectic and non-anorectic pancreatic islet tumors and in the normal islet of Langerhans

    Jensen, P. B., Kristensen, P., Clausen, J. T., Judge, M. E., Hastrup, S., Thim, L., Wulff, B. S., Foged, C., Jensen, J., Holst, Jens Juul & Madsen, O. D., 1999, In: FEBS Letters. 447, p. 139-143

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Treatment of Type 2 diabetes mellitus based on glucagon-like peptide-1

    Holst, Jens Juul, 1999, In: Exp. Opin. Invest. Drugs. 8, p. 1409-1415

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. 1998
  14. Published

    Normalization of fasting glycaemia by intravenous GLP-1 ([7-36 amide] or [7-37]) in type 2 diabetic patients

    Nauck, M. A., Weber, I., Bach, I., Richter, S., Ørskov, Cathrine, Holst, Jens Juul & Schmiegel, W., Nov 1998, In: Diabetic Medicine Online. 15, 11, p. 937-45 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Isolation and molecular characterization of porcine calcitonin gene-related peptide (CGRP) and its endocrine effects in the porcine pancreas

    Rasmussen, T. N., Bersani, M., Schmidt, P., Thim, L., Kofod, H., Jørgensen, P. N., Poulsen, Steen Seier & Holst, Jens Juul, Mar 1998, In: Pancreas. 16, 2, p. 195-204 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Amidated and non-amidated glucagon-like peptide-1 (GLP-1): non-pancreatic effects (cephalic phase acid secretion) and stability in plasma in humans

    Wettergren, A., Pridal, L., Wöjdemann, M. & Holst, Jens Juul, 1998, In: Regul. Pept.. 77, p. 83-88

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Cellular regulation of islet hormone secretion by the incretin hormone glucagon-like peptide 1.

    Holst, Jens Juul, Gromada, K. & Rorsman, P., 1998, In: Pflugers Arch.. 435, p. 583-594

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Changes in serum leptin do not correlate to total fat mass in patients with thyrotoxicosis

    Zimmermann-Belsing, T., Dreyer, M., Holst, Jens Juul & Feldt-Rasmussen, U., 1998, In: J. Endocrinol.. 49, p. 589-595

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Dipeptidyl peptidase IV inhibition potentiates the insulinotropic effect of glucagon-like peptide 1 in the anesthetized pig.

    Deacon, Carolyn F., Hughes, T. E. & Holst, Jens Juul, 1998, In: Diabetes. 47, p. 764-769

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Dipeptidyl peptidase IV resistant analogues of glucagon-like peptide-1 which have extended metabolic stability and improved biological activity

    Deacon, Carolyn F., Knudsen, L. B., Madsen, K., Wiberg, F. C., Jacobsen, O. & Holst, Jens Juul, 1998, In: Diabetologia. 41, p. 271-278

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Discovery of amino acid variants in the human glucose-dependent insulinotropic polypeptide (GIP) receptor: the impact on the pancreatic beta cell responses and functional expression studies in CHL cells

    Almind, K., Ambye, L., Urhammer, S. A., Hansen, T., Echwald, S. M., Holst, Jens Juul, Gromada, J. L., Thorens, B. & Pedersen, O., 1998, In: Diabetologia. 41, p. 1194-1198

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Distal small bowel hormones: Correlation with fasting antroduodenal motility and gastric emptying

    Naslund, E., Gryback, P., Backman, L., Jacobsson, H., Holst, Jens Juul, Theodorsson, E. & Hellstrom, P. M., 1998, In: Dig. Dis. Sci.. 43, p. 945-952

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Exaggerated secretion of glucagon-like peptide-1 (GLP-1) could cause reactive hypoglycaemia

    Toft-Nielsen, M., Madsbad, Sten & Holst, Jens Juul, 1998, In: Diabetologia. 41, 10, p. 1180-1186 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Glucagon-like peptide 1 (7-36) amide stimulates exocytosis in human pancreatic beta-cells by both proximal and distal regulatory steps in stimulus-secretion coupling

    Gromada, J., Bokvist, K., Ding, W. G., Holst, Jens Juul, Nielsen, Jens Høiriis & Rorsman, P., 1998, In: Diabetes. 47, 1, p. 57-65 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Glucagon-like peptide 1 increases mass but not frequency or orderliness of pulsatile insulin secretion

    Porksen, N., Grøfte, T., Nyholm, B., Holst, Jens Juul, Pincus, S. M., Veldhuis, J. D., Schmitz, O. & Butler, P. C., 1998, In: Diabetes. 47, p. 45-49

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Glucagon-like peptide 1 promotes satiety and suppresses energy intake in humans

    Flint, A., Raben, Anne, Astrup, A. & Holst, Jens Juul, 1998, In: Journal of Clinical Investigation. 101, 3, p. 515-520 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Glucagon-like peptide-1 - a new hormone and a new drug

    Holst, Jens Juul, 1998, In: Ugeskrift for læger. 160, p. 2371-2377

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Glucagon-like peptide-1 inhibits gastropancreatic function by inhibiting central parasympathetic outflow

    Wettergren, A., Wojdemann, M. & Holst, Jens Juul, 1998, In: Am. J. Physiol.. 275, p. G984-G992

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Glucagon-like peptide-1 retards gastric emptying and small bowel transit in the rat: Effect mediated through central or enteric nervous mechanisms

    Tolessa, T., Gutniak, M. K., Holst, Jens Juul, Efendic, S. & Hellstrom, P. M., 1998, In: Dig. Dis. Sci.. 43, p. 2284-2290

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Glucagon-like peptide-2 inhibits centrally induced antral motility in pigs

    Wojdemann, M., Wettergren, A., Hartmann, B. & Holst, Jens Juul, 1998, In: Scandinavian Journal of Gastroenterology. 33, p. 828-832

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Importance of small bowel peptides for the improved glucose metabolism 20 years after jejunoileal bypass for obesity

    Naslund, E., Backman, L., Holst, Jens Juul, Theodorsson, E. & Hellstrom, P. M., 1998, In: Obes. Surg.. 8, p. 253-260

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Influence of glucagon-like peptide 1 on fasting glycemia in type 2 diabetic patients treated with insulin after sulfonylurea secondary failure

    Nauck, M. A., Sauerwald, A., Ritzel, R., Holst, Jens Juul & Schmiegel, W., 1998, In: Diabetes Care. 21, p. 1925-1931

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Inhibition of human gastric lipase secretion by glucagon-like peptide-1

    Wojdemann, M., Wettergren, A., Sternby, B., Holst, Jens Juul, Larsen, S., Rehfeld, J. F. & Olsen, O., 1998, In: Dig. Dis. Sci.. 43, p. 799-805

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Inhibition of the activity of dipeptidyl-peptidase IV as a treatment for type 2 diabetes

    Holst, Jens Juul & Deacon, Carolyn F., 1998, In: Diabetes. 47, p. 1663-1670

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Inhibitory effect of glucagon-like peptide-1 on small bowel motility. Fasting but not fed motility inhibited via nitric oxide independently of insulin and somatostatin

    Tolessa, T., Gutniak, M. K., Holst, Jens Juul, Efendic, S. & Hellstrom, P. M., 1998, In: J. Clin. Invest.. 102, p. 764-774

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Normalization of sting glycemia by intravenous GLP-1 (7-36amide) or (7-37) in Type 2 diabetic patients

    Nauck, M. A., Weber, I., Bach, I., Richter, S. H., Ørskov, C., Holst, Jens Juul & Schmiegel, W., 1998, In: Diabetic Medicine. 15, p. 937-945

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Nutrients of animal origin and function of gut hormones

    Holst, Jens Juul, 1998, Food and Health: Role of Animal Products. Paris: Elsevier, p. 13-22

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  38. Published

    Obesity - did anything happen since leptin?

    Holst, Jens Juul, 1998, In: Ugeskrift for læger. 160, p. 1182-1184

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    On the treatment of diabetes mellitus with glucagon-like peptide-1.

    Holst, Jens Juul, Deacon, Carolyn F., Toft-Nielsen, M. & Bjerre-Knudsen, L., 1998, In: Annals of the New York Academy of Sciences. 865, p. 336-343

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Overnight GLP-1 normalizes fasting but not daytime plasma glucose levels in NIDDM patients

    Willms, B., Idowu, K., Holst, Jens Juul, Creutzfeldt, W. & Nauck, M. A., 1998, In: Exp. Clin. Endocrinol. Diabetes. 106, p. 103-107

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Prolonged and enhanced secretion of glucagon-like peptide 1 (7-36 amide) after oral sucrose due to alpha-glucosidase inhibition (acarbose) in Type 2 diabetic patients

    Seifarth, C., Bergmann, J., Holst, Jens Juul, Ritzel, R., Schmiegel, W. & Nauck, M. A., 1998, In: Diabet. Med.. 15, p. 485-491

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Regulatory Peptides of the Gut

    Holst, Jens Juul, 1998, Small Bowel Disorders. Kluwer Academic Publishers

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  43. Published

    The ethanol augmentation of glucose-induced insulin secretion is abolished by calcium antagonism with nifedipine: No evidence for a role of glucagon-like peptide-1 (GLP-1)

    Svartberg, J., Holst, Jens Juul, Gutniak, M. K. & Adner, N., 1998, In: Pancreas. 16, p. 66-71

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    The inhibitory effect of glucagon-like peptide-1 (7-36) amide on antral motility is antagonized by its N-terminally truncated primary metabolite GLP-1 (9-36) amide.

    Wettergren, A., Wojdemann, M. & Holst, Jens Juul, 1998, In: Peptides. 19, p. 877-882

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Transplantable rat glucagonomas cause acute onset of severe anorexia and adipsia despite highly elevated NPY mRNA levels in the hypothalamic arcuate nucleus

    Jensen, P. B., Blume, N., Mikkelsen, J. D., Larsen, P. J., Jensen, H. I., Holst, Jens Juul & Madsen, O. D., 1998, In: J. Clin. Invest.. 101, p. 503-510

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Treatment of type 2 diabetes with glucagonlike peptide 1

    Holst, Jens Juul, 1998, In: Current Opinion in Endocrin. and Diabetes. 5, p. 108-115

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. 1997
  48. Published

    Glucagon-like peptide 1 inhibition of gastric emptying outweighs its insulinotropic effects in healthy humans

    Nauck, M. A., Niedereichholz, U., Ettler, R., Holst, Jens Juul, Ørskov, Cathrine, Ritzel, R. & Schmiegel, W. H., Nov 1997, In: American Journal of Physiology (Consolidated). 273, 5 Pt 1, p. E981-8

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Short-term insulin treatment prevents the diabetogenic action of streptozotocin in rats

    Thulesen, J., Ørskov, Cathrine, Holst, Jens Juul & Poulsen, Steen Seier, Jan 1997, In: Endocrinology. 138, 1, p. 62-68 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    A double-blind placebo-controlled study on the effects of omeprazole on gut hormone secretion and gastric emptying rate.

    Rasmussen, L., Qvist, N., Øster-Jørgensen, E., Rehfeld, J. F., Holst, Jens Juul & Pedersen, S. A., 1997, In: Scandinavian Journal of Gastroenterology. 32, p. 900-905

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Altered postprandial motility in chronic pancreatitis: role of malabsorption.

    Layer, P., v.d. Ohe, M. R., Grandt, D., Holst, Jens Juul, Jansen, J. B. M. J., Holtmann, G., Keller, J. & Goebell, H., 1997, In: Today in Medicine. Gastroenterology. 112, p. 1624-1634

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Bombesin inhibits histamine release from the rat oxyntic mucosa by a somatostatin-dependent mechanism.

    Sandvik, A. K., Brenna, E., Sundan, A., Holst, Jens Juul & Waldum, H. L., 1997, In: Scandinavian Journal of Gastroenterology. 30, p. 427-432

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Circulating GRP and gastrin in fetal lambs in response to luminal infusion of fluids

    Sangild, Per Torp, Hilsted, L., Bjørnskov-Bartholdy, L., Holst, Jens Juul & Trahair, J. F., 1997.

    Research output: Contribution to conferencePaperResearch

ID: 4207