Jens Juul Holst
Professor
Endocrinology and Metabolism
Blegdamsvej 3
2200 København N.
- 1999
- Published
Increased intensity of physical activity stimulates subsequent fat intake
Klausen, B., Toubro, S., Ranneries, C., Rehfeld, J. F., Holst, Jens Juul, Christensen, N. J. & Astrup, A., 1999, In: International Journal of Obesity. 23, p. 1282-1287Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibition of dipeptidyl peptidase IV with NVP DPP728 increases plasma GLP-1 (7-36amide) concentrations and improves oral glucose tolerance in obese Zucker rats
Balkan, B., Kwasnik, L., Miserendino, R., Holst, Jens Juul & Lie, X., 1999, In: Diabetologia. 42, p. 1324-1331Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibition of shamfeeding stimulated human gastric acid secretion by glucagon-like peptide-2
Wøjdemann, M., Wettergren, A., Hartmann, B., Hilsted, L. M. & Holst, Jens Juul, 1999, In: J. Clin. Endocrinol. Metab.. 84, p. 2513-2517Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Octreotide suppresses the incretin GLP-1 in patients with acromegally, clinically nonfunctioning pituitary tumours and in healthy subjects
Plöckinger, U., Holst, Jens Juul, Messerschmidt, D., Hopfenmüller, W. & Quabbe, H. J., 1999, In: European Journal of Endocrinology. 140, p. 538-544Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proglucagon cleavage profile in canine L-cells expressing endogenous PC-1/3 and PC-2
Damholt, A. B., Buchan, A. M. J., Holst, Jens Juul & Kofod, H., 1999, In: Endokrinologiya. 140, p. 4800-4808Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Selectivity of prandial glucose regulators: nateglinide, but not repaglinide, accelerates exocytosis in rat pancreatic A-cells
Bokvist, K., Høy, M., Buschard, K., Holst, Jens Juul, Thomsen, M. K. & Gromada, J. L., 1999, In: Eur. J. Pharmacol.. 386, p. 105-111Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tachykinins stimulate acid and pepsinogen secretion in the isolated perfused porcine stomach
Schmidt, P. T., Rasmussen, T. N. & Holst, Jens Juul, 1999, In: Acta Physiologica (Print Edition). 166, p. 335-340Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tachykinins stimulate the release of peptide hormones (glucagon-like peptide-1), and paracrine - (somatostatin) and neurotransmitters (vasoactive intestinal polypeptide) from porcine ileum through NK-1 receptors
Schmidt, P. T., Rickelt, L. F. & Holst, Jens Juul, 1999, In: Digestive Diseases and Sciences. 44, p. 1273-1281Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The arcuate nucleus is pivotal in mediating the anorectic effects of centrally administered leptin
Tang-Christensen, M., Holst, Jens Juul, Hartmann, B. & Vrang, N., 1999, In: NeuroReport. 10, p. 1183-1187Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The hypothalamic satiety peptide CART is expressed in anorectic and non-anorectic pancreatic islet tumors and in the normal islet of Langerhans
Jensen, P. B., Kristensen, P., Clausen, J. T., Judge, M. E., Hastrup, S., Thim, L., Wulff, B. S., Foged, C., Jensen, J., Holst, Jens Juul & Madsen, O. D., 1999, In: FEBS Letters. 447, p. 139-143Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Treatment of Type 2 diabetes mellitus based on glucagon-like peptide-1
Holst, Jens Juul, 1999, In: Exp. Opin. Invest. Drugs. 8, p. 1409-1415Research output: Contribution to journal › Journal article › Research › peer-review
- 1998
- Published
Normalization of fasting glycaemia by intravenous GLP-1 ([7-36 amide] or [7-37]) in type 2 diabetic patients
Nauck, M. A., Weber, I., Bach, I., Richter, S., Ørskov, Cathrine, Holst, Jens Juul & Schmiegel, W., Nov 1998, In: Diabetic Medicine Online. 15, 11, p. 937-45 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Isolation and molecular characterization of porcine calcitonin gene-related peptide (CGRP) and its endocrine effects in the porcine pancreas
Rasmussen, T. N., Bersani, M., Schmidt, P., Thim, L., Kofod, H., Jørgensen, P. N., Poulsen, Steen Seier & Holst, Jens Juul, Mar 1998, In: Pancreas. 16, 2, p. 195-204 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Amidated and non-amidated glucagon-like peptide-1 (GLP-1): non-pancreatic effects (cephalic phase acid secretion) and stability in plasma in humans
Wettergren, A., Pridal, L., Wöjdemann, M. & Holst, Jens Juul, 1998, In: Regul. Pept.. 77, p. 83-88Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cellular regulation of islet hormone secretion by the incretin hormone glucagon-like peptide 1.
Holst, Jens Juul, Gromada, K. & Rorsman, P., 1998, In: Pflugers Arch.. 435, p. 583-594Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Changes in serum leptin do not correlate to total fat mass in patients with thyrotoxicosis
Zimmermann-Belsing, T., Dreyer, M., Holst, Jens Juul & Feldt-Rasmussen, U., 1998, In: J. Endocrinol.. 49, p. 589-595Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dipeptidyl peptidase IV inhibition potentiates the insulinotropic effect of glucagon-like peptide 1 in the anesthetized pig.
Deacon, Carolyn F., Hughes, T. E. & Holst, Jens Juul, 1998, In: Diabetes. 47, p. 764-769Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dipeptidyl peptidase IV resistant analogues of glucagon-like peptide-1 which have extended metabolic stability and improved biological activity
Deacon, Carolyn F., Knudsen, L. B., Madsen, K., Wiberg, F. C., Jacobsen, O. & Holst, Jens Juul, 1998, In: Diabetologia. 41, p. 271-278Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Discovery of amino acid variants in the human glucose-dependent insulinotropic polypeptide (GIP) receptor: the impact on the pancreatic beta cell responses and functional expression studies in CHL cells
Almind, K., Ambye, L., Urhammer, S. A., Hansen, T., Echwald, S. M., Holst, Jens Juul, Gromada, J. L., Thorens, B. & Pedersen, O., 1998, In: Diabetologia. 41, p. 1194-1198Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Distal small bowel hormones: Correlation with fasting antroduodenal motility and gastric emptying
Naslund, E., Gryback, P., Backman, L., Jacobsson, H., Holst, Jens Juul, Theodorsson, E. & Hellstrom, P. M., 1998, In: Dig. Dis. Sci.. 43, p. 945-952Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exaggerated secretion of glucagon-like peptide-1 (GLP-1) could cause reactive hypoglycaemia
Toft-Nielsen, M., Madsbad, Sten & Holst, Jens Juul, 1998, In: Diabetologia. 41, 10, p. 1180-1186 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide 1 (7-36) amide stimulates exocytosis in human pancreatic beta-cells by both proximal and distal regulatory steps in stimulus-secretion coupling
Gromada, J., Bokvist, K., Ding, W. G., Holst, Jens Juul, Nielsen, Jens Høiriis & Rorsman, P., 1998, In: Diabetes. 47, 1, p. 57-65 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide 1 increases mass but not frequency or orderliness of pulsatile insulin secretion
Porksen, N., Grøfte, T., Nyholm, B., Holst, Jens Juul, Pincus, S. M., Veldhuis, J. D., Schmitz, O. & Butler, P. C., 1998, In: Diabetes. 47, p. 45-49Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide 1 promotes satiety and suppresses energy intake in humans
Flint, A., Raben, Anne, Astrup, A. & Holst, Jens Juul, 1998, In: Journal of Clinical Investigation. 101, 3, p. 515-520 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-1 - a new hormone and a new drug
Holst, Jens Juul, 1998, In: Ugeskrift for læger. 160, p. 2371-2377Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-1 inhibits gastropancreatic function by inhibiting central parasympathetic outflow
Wettergren, A., Wojdemann, M. & Holst, Jens Juul, 1998, In: Am. J. Physiol.. 275, p. G984-G992Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-1 retards gastric emptying and small bowel transit in the rat: Effect mediated through central or enteric nervous mechanisms
Tolessa, T., Gutniak, M. K., Holst, Jens Juul, Efendic, S. & Hellstrom, P. M., 1998, In: Dig. Dis. Sci.. 43, p. 2284-2290Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-2 inhibits centrally induced antral motility in pigs
Wojdemann, M., Wettergren, A., Hartmann, B. & Holst, Jens Juul, 1998, In: Scandinavian Journal of Gastroenterology. 33, p. 828-832Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Importance of small bowel peptides for the improved glucose metabolism 20 years after jejunoileal bypass for obesity
Naslund, E., Backman, L., Holst, Jens Juul, Theodorsson, E. & Hellstrom, P. M., 1998, In: Obes. Surg.. 8, p. 253-260Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of glucagon-like peptide 1 on fasting glycemia in type 2 diabetic patients treated with insulin after sulfonylurea secondary failure
Nauck, M. A., Sauerwald, A., Ritzel, R., Holst, Jens Juul & Schmiegel, W., 1998, In: Diabetes Care. 21, p. 1925-1931Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibition of human gastric lipase secretion by glucagon-like peptide-1
Wojdemann, M., Wettergren, A., Sternby, B., Holst, Jens Juul, Larsen, S., Rehfeld, J. F. & Olsen, O., 1998, In: Dig. Dis. Sci.. 43, p. 799-805Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibition of the activity of dipeptidyl-peptidase IV as a treatment for type 2 diabetes
Holst, Jens Juul & Deacon, Carolyn F., 1998, In: Diabetes. 47, p. 1663-1670Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inhibitory effect of glucagon-like peptide-1 on small bowel motility. Fasting but not fed motility inhibited via nitric oxide independently of insulin and somatostatin
Tolessa, T., Gutniak, M. K., Holst, Jens Juul, Efendic, S. & Hellstrom, P. M., 1998, In: J. Clin. Invest.. 102, p. 764-774Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Normalization of sting glycemia by intravenous GLP-1 (7-36amide) or (7-37) in Type 2 diabetic patients
Nauck, M. A., Weber, I., Bach, I., Richter, S. H., Ørskov, C., Holst, Jens Juul & Schmiegel, W., 1998, In: Diabetic Medicine. 15, p. 937-945Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nutrients of animal origin and function of gut hormones
Holst, Jens Juul, 1998, Food and Health: Role of Animal Products. Paris: Elsevier, p. 13-22Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
Obesity - did anything happen since leptin?
Holst, Jens Juul, 1998, In: Ugeskrift for læger. 160, p. 1182-1184Research output: Contribution to journal › Journal article › Research › peer-review
- Published
On the treatment of diabetes mellitus with glucagon-like peptide-1.
Holst, Jens Juul, Deacon, Carolyn F., Toft-Nielsen, M. & Bjerre-Knudsen, L., 1998, In: Annals of the New York Academy of Sciences. 865, p. 336-343Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Overnight GLP-1 normalizes fasting but not daytime plasma glucose levels in NIDDM patients
Willms, B., Idowu, K., Holst, Jens Juul, Creutzfeldt, W. & Nauck, M. A., 1998, In: Exp. Clin. Endocrinol. Diabetes. 106, p. 103-107Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prolonged and enhanced secretion of glucagon-like peptide 1 (7-36 amide) after oral sucrose due to alpha-glucosidase inhibition (acarbose) in Type 2 diabetic patients
Seifarth, C., Bergmann, J., Holst, Jens Juul, Ritzel, R., Schmiegel, W. & Nauck, M. A., 1998, In: Diabet. Med.. 15, p. 485-491Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Regulatory Peptides of the Gut
Holst, Jens Juul, 1998, Small Bowel Disorders. Kluwer Academic PublishersResearch output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
The ethanol augmentation of glucose-induced insulin secretion is abolished by calcium antagonism with nifedipine: No evidence for a role of glucagon-like peptide-1 (GLP-1)
Svartberg, J., Holst, Jens Juul, Gutniak, M. K. & Adner, N., 1998, In: Pancreas. 16, p. 66-71Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The inhibitory effect of glucagon-like peptide-1 (7-36) amide on antral motility is antagonized by its N-terminally truncated primary metabolite GLP-1 (9-36) amide.
Wettergren, A., Wojdemann, M. & Holst, Jens Juul, 1998, In: Peptides. 19, p. 877-882Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transplantable rat glucagonomas cause acute onset of severe anorexia and adipsia despite highly elevated NPY mRNA levels in the hypothalamic arcuate nucleus
Jensen, P. B., Blume, N., Mikkelsen, J. D., Larsen, P. J., Jensen, H. I., Holst, Jens Juul & Madsen, O. D., 1998, In: J. Clin. Invest.. 101, p. 503-510Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Treatment of type 2 diabetes with glucagonlike peptide 1
Holst, Jens Juul, 1998, In: Current Opinion in Endocrin. and Diabetes. 5, p. 108-115Research output: Contribution to journal › Journal article › Research › peer-review
- 1997
- Published
Glucagon-like peptide 1 inhibition of gastric emptying outweighs its insulinotropic effects in healthy humans
Nauck, M. A., Niedereichholz, U., Ettler, R., Holst, Jens Juul, Ørskov, Cathrine, Ritzel, R. & Schmiegel, W. H., Nov 1997, In: American Journal of Physiology (Consolidated). 273, 5 Pt 1, p. E981-8Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Short-term insulin treatment prevents the diabetogenic action of streptozotocin in rats
Thulesen, J., Ørskov, Cathrine, Holst, Jens Juul & Poulsen, Steen Seier, Jan 1997, In: Endocrinology. 138, 1, p. 62-68 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A double-blind placebo-controlled study on the effects of omeprazole on gut hormone secretion and gastric emptying rate.
Rasmussen, L., Qvist, N., Øster-Jørgensen, E., Rehfeld, J. F., Holst, Jens Juul & Pedersen, S. A., 1997, In: Scandinavian Journal of Gastroenterology. 32, p. 900-905Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Altered postprandial motility in chronic pancreatitis: role of malabsorption.
Layer, P., v.d. Ohe, M. R., Grandt, D., Holst, Jens Juul, Jansen, J. B. M. J., Holtmann, G., Keller, J. & Goebell, H., 1997, In: Today in Medicine. Gastroenterology. 112, p. 1624-1634Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bombesin inhibits histamine release from the rat oxyntic mucosa by a somatostatin-dependent mechanism.
Sandvik, A. K., Brenna, E., Sundan, A., Holst, Jens Juul & Waldum, H. L., 1997, In: Scandinavian Journal of Gastroenterology. 30, p. 427-432Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Circulating GRP and gastrin in fetal lambs in response to luminal infusion of fluids
Sangild, Per Torp, Hilsted, L., Bjørnskov-Bartholdy, L., Holst, Jens Juul & Trahair, J. F., 1997.Research output: Contribution to conference › Paper › Research
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Meal induced gut hormone secretion is altered in aerobically trained compared to sedentary young healthy males
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Copenhagen study of overweight patients with coronary artery disease undergoing low energy diet or interval training: the randomized CUT-IT trial protocol
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Whole grain-rich diet reduces body weight and systemic low-grade inflammation without inducing major changes of the gut microbiome: a randomised cross-over trial
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