Jens Juul Holst
Professor
Endocrinology and Metabolism
Blegdamsvej 3
2200 København N.
- 1997
- Published
Defective prohormone processing and altered pancreatic islet morphology in mice lacking active SPC2.
Furuta, M., Yano, H., Zhou, A., Rouille, Y., Holst, Jens Juul, Carroll, R., Ravazzolla, M., Orci, L. & Steiner, D. F., 1997, In: Proc. Natl. Acad. Sci.. 94, p. 6646-6651Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Distribution of glucagon-like peptide-1 and other preproglucagon-derived peptides in the rat hypothalamus and brainstem
Larsen, P. J., Tang-Christensen, M., Holst, Jens Juul & Ørskov, Cathrine, 1997, In: Neuroscience. Vol. 77, No. 1, p. 257-270Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of GLP-1 on gastric and pancreatic exocrine secretion and on gastrointestinal motility.
Nauck, M. A., Schepp, W., Holst, Jens Juul & Schmiegel, W. H., 1997, The Insulintropic Gut Hormone Glucagon-Like Peptide-1, Front Diabetes vol. 13. Basel: Karger, p. 194-206Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
Effects of glucagon-like peptide-1 (7-36amide) on whole body protein metabolism in healthy man.
Shalev, A., Holst, Jens Juul & Keller, U., 1997, In: European Journal of Clinical Investigation. 27, p. 10-16.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of glucagon-like peptide-1 on islet function and insulin sensitivity in non-insulin dependent diabetes mellitus.
Ahrén, B., Larsson, H. & Holst, Jens Juul, 1997, In: J. Clin. Endocrinol. Metab.. 82, p. 473-478Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Einfluss von subkutanem GLP-1 auf die frühe und langsame Phase der Insulin-sekretion nach intravenöser Glukosebelastung bei gesunden Probanden.
Ritzelt, R., Ørskov, C., Holst, Jens Juul, Schmiegel, W. & Nauck, M. A., 1997, In: Diabetes und Stoffwechsel. 6, p. 64-69.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Enteroglucagon
Holst, Jens Juul, 1997, In: Annual Reviews of Physiology. 59, p. 257-272Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GIP and GLP-1 after oral glucose in postmenopausal women with impaired glucose tolerance.
Ahrén, B., Larsson, H. & Holst, Jens Juul, 1997, In: European Journal of Endocrinology. 137, p. 127-131Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gastrointestinal hormones and gastric emptying 20 years after jejunoileal bypass for massive obesity.
Näslund, E., Grybäck, P., Hellström, P. M., Jacobsson, H., Holst, Jens Juul, Theodorsson, E. & Backmann, L., 1997, In: International Journal of Obesity. 21, p. 387-392Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-1 (GLP-1) as a new therapeutic approach for type-2 diabetes.
Nauck, M. A., Holst, Jens Juul, Willms, B. & Schmiegel, W., 1997, In: Exp. Clin. Endocrinol. Diabetes. 105, p. 187-195Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-1 (GLP-17-36amide) reduces hepatic glucose production indirectly through changes in insulin and glucagon secretion.
Larsson, H., Holst, Jens Juul & Ahrén, B., 1997, In: Acta Phys. Scand.. 160, p. 413-422Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-1 7-36amide and peptide YY have additive inhibitory effects on gastric acid secretion in man.
Wettergren, A., Maina, P., Boesby, S. & Holst, Jens Juul, 1997, In: Scandinavian Journal of Gastroenterology. 32, p. 552-555Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide-1 promotes satiety and suppresses energy intake in humans
Flint, A., Raben, A., Holst, Jens Juul & Astrup, A., 1997, International journal of obesity. 21 ed. European Association for the Study of Obesity, p. 16 1 p.Research output: Chapter in Book/Report/Conference proceeding › Article in proceedings › Research
- Published
Glucose absorption and the release of insulin, gastric inhibitory polypeptide, and glucagon-like peptide-1 in patients after total colectomy.
Palnæs Hansen, C., Andreassen, J. & Holst, Jens Juul, 1997, In: Scandinavian Journal of Gastroenterology. 32, p. 473-477Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Holder GLP-1 som nyt terapeutisk princip i diabetesbehandlingen hvad det lovede?
Holst, Jens Juul, 1997, In: Tidsskrift for Diabetesbehandling. 2(7), p. 16-22Research output: Contribution to journal › Journal article › Research
- Published
Metabolism of oral glucose in pancreas transplant recipients with normal and impaired glucose tolerance.
Christiansen, E., Tibell, A., Vølund, A., Holst, Jens Juul, Rasmussen, K., Schäffer, L. & Madsbad, S., 1997, In: J. Clin. Endocrinol. Metab.. 82, p. 2299-2307Research output: Contribution to journal › Journal article › Research
- Published
Non-insulin-dependent diabetes mellitus - new drugs?
Holst, Jens Juul, 1997, In: Drug Discovery Today. 2, p. 128-129Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Novel Mody3 Mutations in the Hepatocyte Factor-1a Gene. Evidence for a Hyperexcitabillity of Pancreatic ß-cells to Intravenous Secretagogues in a Glucosetolerant Carrier of a P447L Mutation
Hansen, T., Eiberg, Hans Rudolf Lytchoff, Rouard, M., Vaxillaire, M., Møller, A. M., Rasmussen, S. K., Fridberg, M. & Holst, Jens Juul, 1997, In: Diabetes. 46, p. 726-730Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PACAP 1-38 as neurotransmitter in the pig pancreas: PACAP-receptor activation revealed by the antagonist PACAP 6-38.
Tornøe, K., Hannibal, J., Fahrenkrug, J. & Holst, Jens Juul, 1997, In: Am. J. Physiol.. 273, p. G436-G446Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pituitary adenylate-cyclase-activating polypeptide stimulates insulin and glucagon secretion in humans.
Filipson, K., Tornøe, K., Holst, Jens Juul & Ahrén, B., 1997, In: J. Clin. Endocrinol. Metab.. 82, p. 3093-3098Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Posttranslational processing of proglucagon and postsecretory fate of proglucagon products.
Holst, Jens Juul, Ørskov, C., Hartmann, B. & Deacon, Carolyn F., 1997, The Insulinotropic Gut Hormone Glucagon-like Peptide-1.. Basel: Karger, p. 24-48Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
Short term insulin treatment prevents the diabetogenic action of streptozotocin in rats
Thulesen, J., Ørskov, Cathrine, Holst, Jens Juul & Poulsen, Steen Seier, 1997, In: Endokrinologiya. Vol. 138, No. 1, p. 62-68Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The inhibitory effect of glucagon-like peptide-1 (GLP-1) 7-36 amide on gastric acid secretion in humans depends on an intact vagal innervation.
Wettergren, A., Wøjdemann, M., Meisner, S., Stadil, F. & Holst, Jens Juul, 1997, In: Gut. 40, p. 597-601Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The pathogenesis of non-insulin dependent diabetes mellitus involves a defective expression of the GIP receptor.
Holst, Jens Juul, Gromada, J. L. & Nauck, M. A., 1997, In: Diabetologia. 40, p. 984-986Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The release of gastric inhibitory peptide, glucagon-like peptide-1, and insulin after oral glucose test in colectomized subjects.
Palnæs Hansen, C., Andreassen, J. & Holst, Jens Juul, 1997, In: Scandinavian Journal of Gastroenterology. 32, p. 473-477Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Use of antagonists to define tachykininergic control of intestinal motility in pigs.
Schmidt, P. & Holst, Jens Juul, 1997, In: Peptides. 18, p. 373-379Research output: Contribution to journal › Journal article › Research › peer-review
- 1996
- Published
On the effects of glucagon-like peptide-1 on blood glucose regulation in normal and diabetic subjects
Holst, Jens Juul, Toft-Nielsen, M. B., Ørskov, Cathrine, Nauck, M. & Willms, B., 26 Dec 1996, In: Annals of the New York Academy of Sciences. 805, p. 729-36 8 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Effects of subcutaneous glucagon-like peptide 1 (GLP-1 [7-36 amide]) in patients with NIDDM
Nauck, M. A., Wollschläger, D., Werner, J., Holst, Jens Juul, Ørskov, Cathrine, Creutzfeldt, W. & Willms, B., Dec 1996, In: Diabetologia. 39, 12, p. 1546-53 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GLP-1 does not not acutely affect insulin sensitivity in healthy man
Orskov, L., Holst, Jens Juul, Møller, J., Ørskov, Cathrine, Møller, N., Alberti, K. G. & Schmitz, O., Oct 1996, In: Diabetologia. 39, 10, p. 1227-32 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tachykinins mediate vagal inhibition of gastrin secretion in pigs
Schmidt, P., Poulsen, Steen Seier, Hilsted, Linda, Rasmussen, T. N. & Holst, Jens Juul, Oct 1996, In: Gastroenterology. 111, 4, p. 925-35 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Induction of insulin and islet amyloid polypeptide production in pancreatic islet glucagonoma cells by insulin promoter factor 1
Serup, P., Jensen, J., Andersen, F. G., Jørgensen, Mette Christine, Blume, N., Holst, Jens Juul & Madsen, O. D., 20 Aug 1996, In: Proceedings of the National Academy of Sciences of the United States of America. 93, 17, p. 9015-20 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Secretion of the incretin hormones glucagon-like peptide-1 and gastric inhibitory polypeptide correlates with insulin secretion in normal man throughout the day
Ørskov, Cathrine, Wettergren, A. & Holst, Jens Juul, Jul 1996, In: Scandinavian Journal of Gastroenterology. 31, 7, p. 665-70 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide I receptors in the subfornical organ and the area postrema are accessible to circulating glucagon-like peptide I
Ørskov, Cathrine, Poulsen, Steen Seier, Møller, Morten & Holst, Jens Juul, Jun 1996, In: Diabetes. 45, 6, p. 832-5 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagonostatic actions and reduction of fasting hyperglycemia by exogenous glucagon-like peptide I(7-36) amide in type I diabetic patients
Creutzfeldt, W. O., Kleine, N., Willms, B., Ørskov, Cathrine, Holst, Jens Juul & Nauck, M. A., Jun 1996, In: Diabetes Care. Supplement. 19, 6, p. 580-6 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Release of glucagon-like peptide 1 (GLP-1 [7-36 amide]), gastric inhibitory polypeptide (GIP) and insulin in response to oral glucose after upper and lower intestinal resections
Nauck, M. A., Siemsglüss, J., Ørskov, Cathrine & Holst, Jens Juul, Mar 1996, In: Zeitschrift fur Gastroenterologie. 34, 3, p. 159-66 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gastric emptying, glucose responses, and insulin secretion after a liquid test meal: effects of exogenous glucagon-like peptide-1 (GLP-1)-(7-36) amide in type 2 (noninsulin-dependent) diabetic patients
Willms, B., Werner, J., Holst, Jens Juul, Ørskov, Cathrine, Creutzfeldt, W. & Nauck, M. A., Jan 1996, In: Endocrinology. 81, 1, p. 327-32 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gastrin release in the fetal lamb in response to luminal infusion of amniotic fluid, milk or GRP
Sangild, Per Torp, Hilsted, L., Bjørnskov-Bartholdy, L., Holst, Jens Juul & Trahair, J. F., 1996. 1 p.Research output: Contribution to conference › Paper › Research
- Published
Impaired insulin-stimulated nonoxidative glucose metabolism in pancreas-kidney transplant recipients: dose-response effects of insulin on glucose turnover
Christiansen, E., drb459, drb459, Tibell, A., Hother-Nielsen, O., Holst, Jens Juul, Pedersen, O. & Madsbad, Sten, 1996, In: Diabetes. 45, 9, p. 1267-75 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Positive effects on plasma glucose & appetite by industrial modification of starch
Raben, A., Andersen, K., Karberg, M. A., Holst, Jens Juul & Astrup, A., 1996. 1 p.Research output: Contribution to conference › Poster › Research
- 1995
- Published
Both subcutaneously and intravenously administered glucagon-like peptide-1 are rapidly degraded from the amino terminus in type II diabetic patients and in healthy subjects.
Deacon, Carolyn F., Nauck, M. A., Nielsen, M. T., Pridal, L. & Holst, Jens Juul, 1995, In: Diabetes. 44, p. 1126-1131Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Comparison of sandwich ELISA and RIA for determination of exogenous GLP-1 (7-36 amide) in plasma.
Pridal, L., Ingwersen, S. H., Larsen, F. S., Holst, Jens Juul, Adelhorst, K. & Kirk, O., 1995, In: J Pharmaceutical and Biomedical Analysis. 13, p. 841-850Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Degradation of glucagon-like peptide-1 in vitro yields an N-terminally truncated peptide which is a major endogenous metabolite in vivo.
Deacon, Carolyn F., Johnsen, A. H. & Holst, Jens Juul, 1995, In: Journal of Clinical Endocrinology and Metabolism. 80, p. 952-957Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of 17-norleucine-VIP on gastroduodenal motility relative to serum VIP concentration and blockade of NOS.
Holle, G. E., Steinbach, E., Wünsch, E. & Holst, Jens Juul, 1995, In: Am. J. Physiol.. 269, p. G584-G590Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of endogenous hypergastrinemia on gastrin receptor expressing human colon carcinoma transplanted to athymic rats.
Chu, M., Franzén, L., Rehfeld, J. F., Holst, Jens Juul & Borch, K., 1995, In: Today in Medicine. Gastroenterology. 109, p. 1415-1420Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gene expression of pituitary adenylate cyclase activating polypeptide (PACAP) in the rat hypothalamus.
Hannibal, J., Mikkelsen, J. D., Clausen, H., Holst, Jens Juul, Wulff, B. S. & Fahrenkrug, J., 1995, In: Regulatory Peptides. 55, p. 133-148Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide 1 (7-36 amide) secretion in response to luminal sucrose from the upper and lower gut. A study using a-glucosidase inhibition (acarbose)
Qualmann, C., Nauck, M. A., Holst, Jens Juul, Ørskov, Cathrine & Creutzfeldt, W., 1995, In: Scandinavian Journal of Gastroenterology. 30, p. 892-896Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucagon-like peptide 1 (GLP-1)(7-36 amide) secretion in response to luminal sucrose from the upper and lower gut. A study using alpha-glucosidase inhibition (acarbose).
Qualmann, C., Nauck, M. A., Holst, Jens Juul, Ørskov, C. & Creutzfeldt, W., 1995, In: Scandinavian Journal of Gastroenterology. 30, p. 892-896Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Histochemical, pharmacological, biochemical and chromatographic evidence that pituitary adenylyl cyclase activating peptide is involved in inhibitory neurotransm.in the taenia of the guinea-pig caecum
McConalogue, K., Furness, J. B., Vremec, M. A., Holst, Jens Juul, Tornøe, K. & Marley, P. D., 1995, In: J. Autonom Nerv. System. 50, p. 311-322Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human Glucagon-like peptide-1, - six important topics.
Holst, Jens Juul, 1995, Gastrointestinal Tract and Endocrine System.. Dordrecht/Boston/London: Kluwer Academic Publishers, p. 537-546Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
Human colon produces fully processed glucagon-like peptide-1 (7-36 amide).
Deacon, Carolyn F., Johnsen, A. H. & Holst, Jens Juul, 1995, In: FEBS Letters. 372, p. 269-272.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 4207
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Meal induced gut hormone secretion is altered in aerobically trained compared to sedentary young healthy males
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Copenhagen study of overweight patients with coronary artery disease undergoing low energy diet or interval training: the randomized CUT-IT trial protocol
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Whole grain-rich diet reduces body weight and systemic low-grade inflammation without inducing major changes of the gut microbiome: a randomised cross-over trial
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