Thue W. Schwartz
Professor
Schwartz Group
Blegdamsvej 3B, Mærsk Tårnet, 6. sal, 2200 København N.
Member of:
- Published
The arginine of the DRY motif in transmembrane segment III functions as a balancing micro-switch in the activation of the β2-adrenergic receptor
Hansen, L. V., Groenen, M., Nygaard, R., Frimurer, Thomas Michael, Holliday, N. D. & Schwartz, Thue W., 14 Sep 2012, In: Journal of Biological Chemistry. 287, 38, p. 31973-82 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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GPR119 as a fat sensor
Hansen, Harald S., Rosenkilde, Mette, Holst, Jens Juul & Schwartz, Thue W., Jul 2012, In: Trends in Pharmacological Sciences. 33, 7, p. 374-81 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Studies of relationships between variation of the human G protein-coupled receptor 40 Gene and Type 2 diabetes and insulin release
Hamid, Y. H., Vissing, H., Holst, Birgitte, Urhammer, S. A., Pyke, C., Hansen, S. K., Glümer, C., Borch-Johnsen, K., Jørgensen, T., Schwartz, Thue W., Pedersen, O. & Hansen, Torben, 2005, In: Diabetic Medicine. 22, 1, p. 74-80 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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International Union of Basic and Clinical Pharmacology. XCIV. Adhesion G protein-coupled receptors
Hamann, J., Aust, G., Araç, D., Engel, F. B., Formstone, C., Fredriksson, R., Hall, R. A., Harty, B. L., Kirchhoff, C., Knapp, B., Krishnan, A., Liebscher, I., Lin, H-H., Martinelli, D. C., Monk, K. R., Cornelia Peeters, M., Piao, X., Prömel, S., Schöneberg, T., Schwartz, T. W. & 9 others, , Apr 2015, In: Pharmacological Reviews. 67, 2, p. 338-67 30 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Neurotensin Is Co-Expressed, Co-Released And Acts Together With Glp-1 And Pyy In Enteroendocrine Control Of Metabolism
Grunddal, Kaare Villum, Ratner, C. F., Svendsen, B., Sommer, F., Engelstoft, M. S., Madsen, A. N., Pedersen, Jens, Nøhr, M. K., Egerod, Kristoffer Lihme, Nawrocki, A. R., Kowalski, T., Howard, A. D., Poulsen, Steen Seier, Offermanns, S., Bäckhed, G. F., Holst, Jens Juul, Holst, Birgitte & Schwartz, Thue W., Jan 2016, In: Endocrinology. 157, 1, p. 176-94 19 p., en20151600.Research output: Contribution to journal › Journal article › Research › peer-review
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G-Protein-Coupled Receptor 91-Dependent Signalling Does Not Influence Vascular Inflammation and Atherosclerosis in Hyperlipidaemic Mice
Griepke, S., Trauelsen, Mette, Nilsson, M. D., Hansen, J., Steffensen, L. B., Schwartz, Thue W. & Ketelhuth, D. F. J., 2023, In: Cells. 12, 21, 14 p., 2580.Research output: Contribution to journal › Journal article › Research › peer-review
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N-acyl taurines are endogenous lipid messengers that improve glucose homeostasis
Grevengoed, Trisha Jean, Trammell, Sam, McKinney, M. K., Petersen, N., Cardone, R. L., Svenningsen, J. S., Ogasawara, D., Nexøe-Larsen, C. C., Knop, Filip Krag, Schwartz, Thue W., Kibbey, R. G., Cravatt, B. F. & Gillum, M. P., 2019, In: Proceedings of the National Academy of Sciences of the United States of America. 116, 49, p. 24770-24778Research output: Contribution to journal › Journal article › Research › peer-review
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Family and population-based studies of variation within the ghrelin receptor locus in relation to measures of obesity
Gjesing, A. P., Larsen, L. H., Torekov, S. S., Hainerová, I. A., Kapur, R., Johansen, A., Albrechtsen, A., Boj, S., Holst, B., Harper, A., Urhammer, S. A., Borch-Johnsen, K., Pisinger, C. H., Echwald, S. M., Eiberg, H. R. L., Astrup, A., Lebl, J., Ferrer, J., Schwartz, T. W., Hansen, T. & 1 others, , 2010, In: P L o S One. 5, 4, 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Molecular interactions of cyclam and bicyclam non-peptide antagonists with the CXCR4 chemokine receptor
Gerlach, L., Skerlj, R. T., Bridger, G. J. & Schwartz, Thue W., 2001, In: Journal of Biological Chemistry. 276 (17), p. 14153-14160Research output: Contribution to journal › Journal article › Research › peer-review
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Metal ion enhanced binding of AMD3100 to Asp262 in the CXCR4 receptor
Gerlach, L. O., Jakobsen, J. S., Jensen, K. P., Rosenkilde, Mette, Skerlj, R. T., Ryde, U., Bridger, G. J. & Schwartz, Thue W., 2003, In: Biochemistry. 42, 3, p. 710-7 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Molecular basis for agonism in the BB3 receptor: an epitope located on the interface of transmembrane-III, -VI, and -VII
Gbahou, F., Holst, Birgitte & Schwartz, Thue W., 2010, In: Journal of Pharmacology and Experimental Therapeutics. 333, 1, p. 51-9 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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[Leu31, Pro34]neuropeptide Y: a specific Y1 receptor agonist
Fuhlendorff, J., Gether, Ulrik, Aakerlund, L., Langeland-Johansen, N., Thøgersen, H., Melberg, S. G., Olsen, U. B., Thastrup, Ole & Schwartz, Thue W., 1990, In: Proceedings of the National Academy of Sciences of the United States of America. 87, 1, p. 182-6 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Model-Based Discovery of Synthetic Agonists for the Zn2+-Sensing G-Protein-Coupled Receptor 39 (GPR39) Reveals Novel Biological Functions.
Frimurer, Thomas Michael, Mende, F., Graae, A., Engelstoft, M. S., Egerod, Kristoffer Lihme, Nygaard, R., Gerlach, L., Hansen, J. B., Schwartz, Thue W. & Holst, Birgitte, 2017, In: Journal of Medicinal Chemistry. 60, 3, p. 886-898 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Localization of HCMV UL33 and US27 in endocytic compartments and viral membranes
Fraile-Ramos, A., Pelchen-Matthews, A., Kledal, T. N., Browne, H., Schwartz, Thue W. & Marsh, M., 2002, In: Traffic - International Journal of Intracellular Transport. 3, 3, p. 218-32 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The human cytomegalovirus US28 protein is located in endocytic vesicles and undergoes constitutive endocytosis and recycling
Fraile-Ramos, A., Kledal, T. N., Pelchen-Matthews, A., Bowers, K., Schwartz, Thue W. & Marsh, M., 2001, In: Molecular Biology of the Cell. 12, 6, p. 1737-49 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Pyruvate dehydrogenase kinase regulates vascular inflammation in atherosclerosis and increases cardiovascular risk
Forteza, M. J., Berg, M., Edsfeldt, A., Sun, J., Baumgartner, R., Kareinen, I., Casagrande, F. B., Hedin, U., Zhang, S., Vuckovic, I., Dzeja, P. P., Polyzos, K. A., Gisterå, A., Trauelsen, M., Schwartz, T. W., Dib, L., Herrmann, J., Monaco, C., Matic, L., Gonçalves, I. & 1 others, , 2023, In: Cardiovascular Research. 119, 7, p. 1524-1536 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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[Fine needle aspiration cytology of mammography screening]
Engvad, B., Laenkholm, A. V., Schwartz, Thue W. & Bak, M., 2009, In: Ugeskrift for læger. 171, 34, p. 2379-2382 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Structural basis for constitutive activity and agonist-induced activation of the enteroendocrine fat sensor GPR119
Engelstoft, M. S., Norn, C., Pedersen, M. H., Holliday, N. D., Elster, L., Lehmann, J., Jones, R. M., Frimurer, Thomas Michael & Schwartz, Thue W., Dec 2014, In: British Journal of Pharmacology. 171, 24, p. 5774-89 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A gut feeling for obesity: 7TM sensors on enteroendocrine cells
Engelstoft, M. S., Egerod, Kristoffer Lihme, Holst, Birgitte & Schwartz, Thue W., 2008, In: Cell Metabolism. 8, 6, p. 447-9 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Research Resource: A Chromogranin A Reporter for Serotonin and Histamine Secreting Enteroendocrine Cells
Engelstoft, M. S., Lund, M. L., Grunddal, Kaare Villum, Egerod, Kristoffer Lihme, Osborne-Lawrence, S., Poulsen, Steen Seier, Zigman, J. M. & Schwartz, Thue W., Nov 2015, In: Molecular endocrinology (Baltimore, Md.). 29, 11, p. 1658-71 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Enteroendocrine cell types revisited
Engelstoft, M. S., Egerod, Kristoffer Lihme, Lund, M. L. & Schwartz, Thue W., Dec 2013, In: Current Opinion in Pharmacology. 13, 6, p. 912-21 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Seven transmembrane G protein-coupled receptor repertoire of gastric ghrelin cells
Engelstoft, M. S., Park, W-M., Sakata, I., Kristensen, L. V., Husted, A. S., Osborne-Lawrence, S., Piper, P. K., Walker, A. K., Pedersen, M. H., Nøhr, M. K., Pan, J., Sinz, C. J., Carrington, P. E., Akiyama, T. E., Jones, R. M., Tang, C., Ahmed, K., Offermanns, S., Egerod, K. L., Zigman, J. M. & 1 others, , Nov 2013, In: Molecular Metabolism. 2, 4, p. 376-92 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Opposite Regulation of Ghrelin and Glucagon-like Peptide-1 by Metabolite G-Protein-Coupled Receptors
Engelstoft, M. S. & Schwartz, Thue W., Sep 2016, In: Trends in Endocrinology and Metabolism. 27, 9, p. 665-675 11 p.Research output: Contribution to journal › Review › Research › peer-review
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An aromatic region to induce a switch between agonism and inverse agonism at the ghrelin receptor
Els, S., Schild, E., Petersen, P. S., Kilian, T., Mokrosinski, J., Frimurer, Thomas Michael, Chollet, C., Schwartz, Thue W., Holst, Birgitte & Beck-Sickinger, A. G., 13 Sep 2012, In: Journal of Medicinal Chemistry. 55, 17, p. 7437-49 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Metal-ion sites as structural and functional probes of helix-helix interactions in 7TM receptors
Elling, C. E., Thirstrup, K., Nielsen, S. M., Hjorth, S. A. & Schwartz, Thue W., 1997, In: Annals of the New York Academy of Sciences. 814, p. 142-151Research output: Contribution to journal › Journal article › Research › peer-review
ID: 11601
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Family and population-based studies of variation within the ghrelin receptor locus in relation to measures of obesity
Research output: Contribution to journal › Journal article › Research › peer-review
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2791
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PDZ domain-mediated interactions of G protein-coupled receptors with postsynaptic density protein 95: quantitative characterization of interactions
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612
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Receptor structure-based discovery of non-metabolite agonists for the succinate receptor GPR91
Research output: Contribution to journal › Journal article › Research › peer-review
Published