Thue W. Schwartz

Thue W. Schwartz

Professor

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    ORCID: 0000-0002-0261-6904

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    1. Published

      Structural basis for constitutive activity and agonist-induced activation of the enteroendocrine fat sensor GPR119

      Engelstoft, M. S., Norn, C., Pedersen, M. H., Holliday, N. D., Elster, L., Lehmann, J., Jones, R. M., Frimurer, Thomas Michael & Schwartz, Thue W., Dec 2014, In: British Journal of Pharmacology. 171, 24, p. 5774-89 16 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    2. Published

      Structural basis for GPCR signaling by small polar versus large lipid metabolites-discovery of non-metabolite ligands

      Lückmann, Michael, Trauelsen, Mette, Frimurer, Thomas Michael & Schwartz, Thue W., 2020, In: Current Opinion in Cell Biology. 63, p. 38-48

      Research output: Contribution to journal › Review › Research › peer-review

    3. Published

      Steric hindrance mutagenesis versus alanine scan in mapping of ligand binding sites in the tachykinin NK1 receptor

      Holst, Birgitte, Jensen, S. Z., Elling, C. E., Hjorth, S. A. & Schwartz, Thue W., 1998, In: Molecular Pharmacology. 53, no. 1, p. 166-175

      Research output: Contribution to journal › Journal article › Research › peer-review

    4. Published

      Split-receptors in the tachykinin NK-1 system - mutational analysis of intracellular loop 3

      Nielsen, S. M., Elling, C. E. & Schwartz, Thue W., 1998, In: European Journal of Biochemistry. 251, p. 217-226

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      Single-chain vascular endothelial growth factor variant with antagonist activity

      Boesen, T. P., Soni, B., Schwartz, Thue W. & Halkier, T., 2002, In: Journal of Biological Chemistry. 277, 43, p. 40335-41 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      Similar activation of signal transduction pathways by the herpesvirus-encoded chemokine receptors US28 and ORF74

      McLean, K. A., Holst, Peter Johannes, Martini, L., Schwartz, Thue W. & Rosenkilde, Mette, 2004, In: Virology. 325, 2, p. 241-51 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      Seven transmembrane G protein-coupled receptor repertoire of gastric ghrelin cells

      Engelstoft, M. S., Park, W-M., Sakata, I., Kristensen, L. V., Husted, A. S., Osborne-Lawrence, S., Piper, P. K., Walker, A. K., Pedersen, M. H., Nøhr, M. K., Pan, J., Sinz, C. J., Carrington, P. E., Akiyama, T. E., Jones, R. M., Tang, C., Ahmed, K., Offermanns, S., Egerod, K. L., Zigman, J. M. & 1 others, Schwartz, Thue W., Nov 2013, In: Molecular Metabolism. 2, 4, p. 376-92 17 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    8. Published

      Self-organized metabotyping of obese individuals identifies clusters responding differently to bariatric surgery

      Lappa, D., Meijnikman, A. S., Krautkramer, K. A., Olsson, L. M., Aydin, Ö., Van Rijswijk, A. S., Acherman, Y. I. Z., De Brauw, M. L., Tremaroli, V., Olofsson, L. E., Lundqvist, A., Hjorth, Siv Annegrethe, Ji, B., Gerdes, V. E. A., Groen, A. K., Schwartz, Thue W., Nieuwdorp, M., Bäckhed, F. & Nielsen, J., 2023, In: PLoS ONE. 18, 3, 26 p., e0279335.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Published

      Selective recognition of the membrane-bound CXC3 chemokine, fractal by the human cytomegalovirus-encoded broad-spectrum receptor US28

      Kledal, T. N., Rosenkilde, Mette & Schwartz, Thue W., 1998, In: FEBS Letters. 441, p. 209-214

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Published

      Selective elimination of high constitutive activity or chemokine binding in the human herpesvirus 8 encoded seven transmembrane oncogene ORF74

      Rosenkilde, Mette, Kledal, T. N., Holst, Peter Johannes & Schwartz, Thue W., 2000, In: Journal of Biological Chemistry. 275, 34, p. 26309-15 6 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Rfx6 promotes the differentiation of peptide-secreting enteroendocrine cells while repressing genetic programs controlling serotonin production

      Piccand, J., Vagne, C., Blot, F., Meunier, A., Beucher, A., Strasser, P., Lund, M. L., Ghimire, S., Nivlet, L., Lapp, C., Petersen, N., Engelstoft, M. S., Thibault-Carpentier, C., Keime, C., Correa, S. J., Schreiber, V., Molina, N., Schwartz, Thue W., De Arcangelis, A. & Gradwohl, G., 2019, In: Molecular Metabolism. 29, p. 24-39

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Reversible switching of ultrastrong light-molecule coupling

      Schwartz, Thue W., Hutchison, J. A., Genet, C. & Ebbesen, T. W., 13 May 2011, In: Physical Review - Index. 106, p. 196405 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      Resequencing of 200 human exomes identifies an excess of low-frequency non-synonymous coding variants

      Li, Y., Vinckenbosch, N., Tian, G., Huerta-Sanchez, E., Jiang, T., Jiang, H., Albrechtsen, A., Andersen, G., Cao, H., Korneliussen, T. S., Grarup, N., Guo, Y., Hellman, I., Jin, X., Li, Q., Liu, J., Liu, X., Sparsø, T., Tang, M., Wu, H. & 18 others, Wu, R., Yu, C., Zheng, H., Astrup, A., Bolund, L., Holmkvist, J., Jørgensen, T., Kristiansen, Karsten, Schmitz, O., Schwartz, Thue W., Zhang, X., Li, R., Yang, H., Wang, J., Hansen, Torben, Pedersen, Oluf Borbye, Nielsen, Rasmus & Wang, J., 2010, In: Nature Genetics. 42, 11, p. 969-72 4 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    14. Published

      Research Resource: A Chromogranin A Reporter for Serotonin and Histamine Secreting Enteroendocrine Cells

      Engelstoft, M. S., Lund, M. L., Grunddal, Kaare Villum, Egerod, Kristoffer Lihme, Osborne-Lawrence, S., Poulsen, Steen Seier, Zigman, J. M. & Schwartz, Thue W., Nov 2015, In: Molecular endocrinology (Baltimore, Md.). 29, 11, p. 1658-71 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    15. Published

      Release of PYY from pig intestinal mucosa; luminal and neural regulation

      Sheikh, S. P., Holst, Jens Juul, Ørskov, Cathrine, Ekman, R. & Schwartz, Thue W., Dec 1989, In: Regulatory Peptides. 26, 3, p. 253-66 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Regional distribution of putative NPY Y*U1 receptors and neurons expressing Y*U1 mRNA in forebrain areas of the rat central nervous system

      Larsen, P. J., Sheikh, S. P., Jakobsen, C. R., Schwartz, Thue W. & Mikkelsen, J. D., 1993, In: European Journal of Neuroscience. Vol 5, p. 1622-37

      Research output: Contribution to journal › Journal article › Research › peer-review

    17. Published

      Receptorji s sedmimi transmembranskimi območji (7TM) v luči dimerizacije ter eksperimentalni pristopi za proučevanje njihove dimerizacije in medsebojnih vplivov

      Kubale, V., Pogačnik, A., Schwartz, Thue W. & Vrecl, M., 2008, In: Slovenian Veterinary Research. 45, 3, p. 89-102 14 p.

      Research output: Contribution to journal › Review › Research › peer-review

    18. Published

      Receptor structure-based discovery of non-metabolite agonists for the succinate receptor GPR91

      Trauelsen, Mette, Ulven, Elisabeth Rexen, Hjorth, Siv Annegrethe, Brvar, M., Monaco, C., Frimurer, Thomas Michael & Schwartz, Thue W., Dec 2017, In: Molecular Metabolism. 6, 12, p. 1585-1596 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. Published

      Pyruvate dehydrogenase kinase regulates vascular inflammation in atherosclerosis and increases cardiovascular risk

      Forteza, M. J., Berg, M., Edsfeldt, A., Sun, J., Baumgartner, R., Kareinen, I., Casagrande, F. B., Hedin, U., Zhang, S., Vuckovic, I., Dzeja, P. P., Polyzos, K. A., Gisterå, A., Trauelsen, M., Schwartz, T. W., Dib, L., Herrmann, J., Monaco, C., Matic, L., Gonçalves, I. & 1 others, Ketelhuth, D. F. J., 2023, In: Cardiovascular Research. 119, 7, p. 1524-1536 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    20. Published

      Protective succinate-SUCNR1 metabolic stress signaling gone bad

      Winther, Sally, Trauelsen, Mette & Schwartz, Thue W., 2021, In: Cell Metabolism. 33, 7, p. 1276-1278 3 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      Profiling of G protein-coupled receptors in vagal afferents reveals novel gut-to-brain sensing mechanisms

      Egerod, Kristoffer Lihme, Petersen, N., Timshel, P. N., Rekling, Jens Christian, Wang, Y., Liu, Q., Schwartz, Thue W. & Gautron, L., 2018, In: Molecular Metabolism. 12, p. 62-75 14 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      Processing of pro-CGRP in a rat medullary thyroid carcinoma cell line transfected with protease inhibitors

      Johansen, T. E., Schifter, S., Vogel, Lotte, Tolstoy, S. & Schwartz, Thue W., 1991, In: Molecular and Cellular Endocrinology. 82, 1, p. 51-60 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    23. Published

      Principles of Agonism - Undressing Efficacy

      Schwartz, Thue W. & Ijzermann, A. P., 1998, In: TIPS - Trends in Pharmacological Sciences. 19, no. 11, p. 433-436

      Research output: Contribution to journal › Journal article › Research › peer-review

    24. Published

      Preassociation between the 5-HT7 serotonin receptor and G protein Gs: molecular determinants and association with low potency activation of adenylyl cyclase

      Ulsund, A. H., Dahl, M., Frimurer, Thomas Michael, Manfra, O., Schwartz, Thue W., Levy, F. O. & Andressen, K. W., 2019, In: FASEB Journal. 33, 3, p. 3870-3886

      Research output: Contribution to journal › Journal article › Research › peer-review

    25. Published

      Potent inhibition of HIV-1 infectivity in macrophages and lymphocytes by a novel CCR5 antagonist

      Simmons, G., Clapham, P. R., Picard, L., Offord, R. E., Rosenkilde, Mette, Schwartz, Thue W., Buser, R., Weels, T. N. C. & Proudfoot, A., 1997, In: Kexue (Shanghai). 276, p. 276-279

      Research output: Contribution to journal › Journal article › Research › peer-review

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