Jens Juul Holst

Jens Juul Holst

Professor


  1. 2004
  2. Published

    Similar gastric emptying but greater gastric secretion and GIP release after the ingestion of peptide hydrolysates in man

    Calbet, J. A. L. & Holst, Jens Juul, 2004, In: Eur J Nutrition. 43, p. 127-139

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Stimulation of insulin secretion by intravenous bolus injection and continuous infusion of gastric inhibitory polypeptide in patients with type 2 diabetes and healthy control subjects.

    Meier, J. J., Gallwitz, B., Kask, B., Deacon, Carolyn F., Holst, Jens Juul, Schmidt, W. E. & Nauck, M. A., 2004, In: Diabetes. 53 Suppl 3, p. S220-4

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Supplementation of total parenteral nutrition with butyrate acutely increases structural aspects of intestinal adaptation following and 80% jejunoileal resection in neonatal pigs

    Bartholome, A. L., Albin, D. M., Baker, D. H., Holst, Jens Juul & Tappenden, K. A., 2004, In: J Parenter Enteral Nutr. 28, p. 210-223

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    The incretin approach for diabetes treatment: modulation of islet hormone release by GLP-1 agonism.

    Holst, Jens Juul & Ørskov, Cathrine, 2004, In: Diabetes. 53 Suppl 3, p. S197-204

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    The ¤use of glycaemic index tables to predict glycaemic index of composite breakfast meals

    Flint, A., Møller, B. K., Raben, Anne, Pedersen, D., Tetens, I., Holst, Jens Juul & Astrup, A., 2004, In: British Journal of Nutrition. 91, 6, p. 979-989 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Treatment of type 2 diabetes mellitus with agonists of the GLP-1 receptor or DPP-IV inhibitors.

    Holst, Jens Juul, 2004, In: Expert Opinion on Emerging Drugs. 9, 1, p. 155-66 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. 2003
  9. Published

    Role of gastrointestinal hormones in postprandial reduction of bone resorption

    Henriksen, D. B., Alexandersen, P., Bjarnason, N. H., Vilsbøll, Tina, Hartmann, B., Henriksen, E. E. G., Byrjalsen, I., Krarup, T., Holst, Jens Juul & Christiansen, C., 1 Dec 2003, In: J Bone Miner Res. 18, 12, p. 2180-2190 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Peripheral administration of GLP-2 to humans has no effect on gastric emptying or satiety

    Schmidt, P. T., Näslund, E., Grybäck, P., Jacobsson, H., Hartmann, Bolette, Holst, Jens Juul & Hellström, P. M., 15 Nov 2003, In: Regulatory Peptides. 116, 1-3, p. 21-5 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Small-intestinal dysfunction accompanies the complex endocrinopathy of human proprotein convertase 1 deficiency

    Jackson, R. S., Creemers, J. W. M., Farooqi, I. S., Raffin-Sanson, M-L., Varro, A., Dockray, G. J., Holst, J. J., Brubaker, P. L., Corvol, P., Polonsky, K. S., Ostrega, D., Becker, K. L., Bertagna, X., Hutton, J. C., White, A., Dattani, M. T., Hussain, K., Middleton, S. J., Nicole, T. M., Milla, P. J. & 2 others, Lindley, K. J. & O'Rahilly, S., Nov 2003, In: The Journal of Clinical Investigation. 112, 10, p. 1550-60 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Structural differences between rye and wheat breads but not total fiber content may explain the lower postprandial insulin response to rye bread

    Juntunen, K. S., Laaksonen, D. E., Autio, K., Niskanen, L. K., Holst, Jens Juul, Savolainen, K. E., Liukkonen, K., Poutanen, K. S. & Mykkänen, H. M., Nov 2003, In: Uden navn. 78, 5, p. 957-64 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Characterization of GLP-1 effects on beta-cell function after meal ingestion in humans

    Ahrén, B., Holst, Jens Juul & Mari, A., Oct 2003, In: Diabetes Care. Supplement. 26, 10, p. 2860-4 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Absence of a memory effect for the insulinotropic action of glucagon-like peptide 1 (GLP-1) in healthy volunteers

    Meier, S., Hücking, K., Ritzel, R., Holst, Jens Juul, Schmiegel, W. H. & Nauck, M. A., Sep 2003, In: Hormone and Metabolic Research. Supplement. 35, 9, p. 551-6 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Nitric oxide has tonic inhibitory effect, but is not involved in the vagal control or VIP effects on motility of the porcine antrum

    Schmidt, P. T., Ørskov, Cathrine, Rasmussen, T. N. & Holst, Jens Juul, Sep 2003, In: Scandinavian Journal of Gastroenterology. 38, 9, p. 955-61 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Both GLP-1 and GIP are insulinotropic at basal and postprandial glucose levels and contribute nearly equally to the incretin effect of a meal in healthy subjects

    Vilsbøll, T., Krarup, T., Madsbad, Sten & Holst, Jens Juul, 15 Jul 2003, In: Regulatory Peptides. 114, 2-3, p. 115-21 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    GLP-2-mediated up-regulation of intestinal blood flow and glucose uptake is nitric oxide-dependent in TPN-fed piglets 1

    Guan, X., Stoll, B., Lu, X., Tappenden, K. A., Holst, Jens Juul, Hartmann, Bolette & Burrin, D. G., Jul 2003, In: Gastroenterology. 125, 1, p. 136-47 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Gastric inhibitory polypeptide (GIP) dose-dependently stimulates glucagon secretion in healthy human subjects at euglycaemia

    Meier, J. J., Gallwitz, B., Siepmann, N., Holst, Jens Juul, Deacon, Carolyn F., Schmidt, W. E. & Nauck, M. A., Jun 2003, In: Diabetologia. 46, 6, p. 798-801 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Incretin secretion in relation to meal size and body weight in healthy subjects and people with type 1 and type 2 diabetes mellitus

    Vilsbøll, T., Krarup, T., Sonne, J., Madsbad, Sten, Vølund, A., Juul, A. G. & Holst, Jens Juul, Jun 2003, In: The Journal of clinical endocrinology and metabolism. 88, 6, p. 2706-13 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Insulin secretion and cellular glucose metabolism after prolonged low-grade intralipid infusion in young men

    Jensen, C. B., Storgaard, H., Holst, Jens Juul, Dela, Flemming, Madsbad, Sten & Vaag, Allan, Jun 2003, In: The Journal of clinical endocrinology and metabolism. 88, 6, p. 2775-83 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Introduction of enteral food increases plasma GLP-2 and decreases GLP-2 receptor mRNA abundance during pig development

    Petersen, Y. M., Hartmann, Bolette, Holst, Jens Juul, Le Huerou-Luron, I., Bjørnvad, Charlotte Reinhard & Sangild, Per Torp, Jun 2003, In: Journal of Nutrition. 133, 6, p. 1781-6 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Normalization of glucose concentrations and deceleration of gastric emptying after solid meals during intravenous glucagon-like peptide 1 in patients with type 2 diabetes

    Meier, J. J., Gallwitz, B., Salmen, S., Goetze, O., Holst, Jens Juul, Schmidt, W. E. & Nauck, M. A., Jun 2003, In: The Journal of clinical endocrinology and metabolism. 88, 6, p. 2719-25 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    No effect of physiological concentrations of glucagon-like peptide-2 on appetite and energy intake in normal weight subjects

    Sørensen, L. B., Flint, A., Raben, Anne, Hartmann, Bolette, Holst, Jens Juul & Astrup, A., Apr 2003, In: International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity. 27, 4, p. 450-6 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Role of luminal nutrients and endogenous GLP-2 in intestinal adaptation to mid-small bowel resection

    Dahly, E. M., Gillingham, M. B., Guo, Z., Murali, S. G., Nelson, D. W., Holst, Jens Juul & Ney, D. M., Apr 2003, In: American Journal of Physiology: Gastrointestinal and Liver Physiology. 284, 4, p. G670-82

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Cocaine- and amphetamine-regulated transcript is present in hypothalamic neuroendocrine neurones and is released to the hypothalamic-pituitary portal circuit

    Larsen, P. J., Seier, V., Fink-Jensen, Anders, Holst, Jens Juul, Warberg, J. & Vrang, N., Mar 2003, In: Journal of Neuroendocrinology. 15, 3, p. 219-26 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Differential effects of saturated and monounsaturated fats on postprandial lipemia and glucagon-like peptide 1 responses in patients with type 2 diabetes

    Thomsen, C., Storm, H., Holst, Jens Juul & Hermansen, K., Mar 2003, In: Uden navn. 77, 3, p. 605-11 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    The influence of GLP-1 on glucose-stimulated insulin secretion: effects on beta-cell sensitivity in type 2 and nondiabetic subjects

    Kjems, L. L., Holst, Jens Juul, Vølund, A. & Madsbad, Sten, Feb 2003, In: Diabetes. 52, 2, p. 380-6 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Similar elimination rates of glucagon-like peptide-1 in obese type 2 diabetic patients and healthy subjects

    Vilsbøll, T., Agersø, H., Krarup, T. & Holst, Jens Juul, Jan 2003, In: The Journal of clinical endocrinology and metabolism. 88, 1, p. 220-4 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Absence of a memory effect for the insulinotropic action of glucagon-like peptide 1(GLP-1) in healthy volunteers

    Meier, S., Hücking, K., Ritzelt, R., Holst, Jens Juul, Schmiegel, W. H. & Nauck, M. A., 2003, In: Horm Metab Res. 35, p. 551-556

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Characterization of GLP-1 effects on beta cell function after meal ingestion in humans

    Ahren, B., Holst, Jens Juul & Mari, A., 2003, In: Diabetes Care. 26, p. 2860-2864

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Circulating leptin and thyroid dysfunction.

    Zimmermann-Belsing, T., Brabant, G., Holst, Jens Juul & Feldt-Rasmussen, Ulla, 2003, In: European Journal of Endocrinology. 149, 4, p. 257-71 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Cocaine and amphetamine-regulated transcript (CART) is present in hypothalamic neuroendocrine neurons and is related to the hypothalamo-pituitary portal circuit

    Larsen, P. J., Seier, V., Fink-Jensen, A., Holst, Jens Juul, Warberg, J. & Vrang, N., 2003, In: Journal of Neuroendocrinology. 15, p. 219-226

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Colonic fermentation influences lower esophageal sphincter function in gastroesophageal reflux disease.

    Piche, T., des Varannes, S. B., Sacher-Huvelin, S., Holst, Jens Juul, Cuber, J. C. & Galmiche, J. P., 2003, In: Gastroenterology. 124, 4, p. 894-902 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Comparisons of leptin, incretins and body composition in obese and lean patients with hypopituitarism and healthy individuals

    Mersebach, H., Svendsen, Ole Lander, Holst, Jens Juul, Astrup, A. & Feldt-Rasmussen, Ulla, 2003, In: Clinical Endocrinology. 58, 1, p. 65-71 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Differential effects of saturated and monounsaturated fat on postprandial lipemia and incretin responses in type 2 diabetic subjects

    Thomsen, C., Storm, H., Holst, Jens Juul & Hermansen, K., 2003, In: Am. J. Clin. Nutr.. 77, p. 605-611

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Differential regional metabolism of glucagon in anesthetized pigs.

    Deacon, Carolyn F., Kelstrup, M., Trebbien, R., Klarskov, L., Olesen, M. & Holst, Jens Juul, 2003, In: American Journal of Physiology: Endocrinology and Metabolism. 285, 3, p. E552-60

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Does overnight normalization of plasma glucose by insulin infusion affect assessment of glucose metabolism in type 2 diabetes

    Staehr, P., Højlund, K., Hother-Nielsen, O., Holst, Jens Juul & Beck-Nielsen, H., 2003, In: Diabetic Medicine. 20, p. 816-822

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Effects of GLP-2 treatment and antibiotics on gut structure and function during pig weanling diarrhea

    Nielsen, T. T., Sangild, Per Torp, Elnif, J., Sorensen, K., Leser, T., Holst, Jens Juul, Hartmann, B., Jensen, B. B. & Hedemann, M. S., 2003, Ikke angivet. R.O. Ball (ed.). 2 ed. University of Alberta Press, p. 161-163 3 p.

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearch

  39. Published

    Effects of free fatty acids per se on glucose production, gluconeogenesis, and glycogenolysis.

    Staehr, P., Hother-Nielsen, O., Landau, B. R., Chandramouli, V., Holst, Jens Juul & Beck-Nielsen, H., 2003, In: Diabetes. 52, 2, p. 260-7 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Et æble om dagen

    Larsen, P. J., Holst, Jens Juul & Astrup, A., 2003, In: Politiken. 29, 2 p.

    Research output: Contribution to journalContribution to newspaper - Feature articleCommunication

  41. Published

    Exogenous GLP-2 has only marginal effects on weaning-induced intestinal adaption in piglets

    le Huërou-Luron, I., Petersen, Y. M., Hartmann, B., Holst, Jens Juul & Sangild, Per Torp, 2003, Ikke angivet. R.O. Ball (ed.). 2 ed. University of Alberta Press, p. 164-166 3 p.

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearch

  42. Published

    Functional and immunohistochemical evaluation of porcine neonatal islet-like cell clusters.

    Nielsen, T. B., Yderstraede, K. B., Schrøder, H. D., Holst, Jens Juul, Brusgaard, K. & Beck-Nielsen, H., 2003, In: Cell Transplantation. 12, 1, p. 13-25 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    GLP-1 and GIP are colocalized in a subset of endocrine cells in the small intestine

    Mortensen, K., Christensen, L. L., Holst, Jens Juul & Ørskov, Cathrine, 2003, In: Regulatory Peptides. 114, 2-3, p. 189-96 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    GLP-2 mediated up-regulation of intestinal blood flow and glucose uptake is nitric oxide-dependent in TNP-fed piglets

    Guan, X., Stoll, B., Lu, X., Tappenden, K., Holst, Jens Juul, Hartmann, B. & Burrin, D. G., 2003, In: Today in Medicine. Gastroenterology. 125, p. 136-147

    Research output: Contribution to journalJournal articleResearch

  45. Published

    Gastric inhibitory polypeptide (GIP) does not inhibit gastric emptying in man

    Meier, J. M., Goetze, O., Anstipp, J., Hagemann, D., Holst, Jens Juul, Schmidt, W. E., Gallwitz, B. & Nauck, M. A., 2003, In: Am. J. Physiol.. 16, p. E621-E625

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Gastric inhibitory polypeptide (GIP) dose-dependently stimulates glucagon secretion in healthy human subjects at euglycaemia

    Meier, J. J., Gallwitz, N., Siepmann, N., Holst, Jens Juul, Deacon, Carolyn F., Schmidt, W. E. & Nauck, M. A., 2003, In: Diabetologia. 46, p. 798-801

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Impaired intestinal proglucagon processing in mice lacking prohormone convertase 1.

    Ugleholdt, Randi Kjærsgaard, Zhu, X., Deacon, Carolyn F., Ørskov, Cathrine, Steiner, D. F. & Holst, Jens Juul, 2003, In: Endocrinology. 145, 3, p. 1349-55 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Implementation of GLP-1 based therapy of type 2 diabetes mellitus using DPP-IV inhibitors.

    Holst, Jens Juul, 2003, In: Advances in Experimental Medicine and Biology. 524, p. 263-79 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Incretin secretion in relation to meal size and body weight in healthy subjects and in people with type 1 and type 2 diabetes mellitus

    Vilsbøll, T., Krarup, T., Sonne, J., Madsbad, S., Vølund, A., Juul, A. G. & Holst, Jens Juul, 2003, In: J. Clin. Endocrinol. Metab.. 88, p. 2706-2713

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Insulin secretion and cellular glucose metabolism after prolonged low-grade intralipid infusion in young men

    Jensen, C. B., Storgaard, H., Holst, Jens Juul, Dela, F., Madsbad, Sten & Vaag, A. A., 2003, In: Journal of Clinical Endocrinology and Metabolism. 88, 6, p. 2775-2783 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Introduction of enteral food increases plasma GLP-2 and decreases GLP-2 receptor mRNA abundance during pig development

    Petersen, Y. M., Hartmann, B., Holst, Jens Juul, Le Huërou-Luron, I., Bjørnvad, Charlotte Reinhard & Sangild, Per Torp, 2003, In: Journal of Nutrition. 133, 6, p. 1781-1786 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Lower blood glucose, hyperglucagonemia and pancreatic alpha cell hyperplasia in glucagon receptor knockout mice

    Gelling, R. W., Du, X. Q., Dichmann, D. S., Rømer, J., Huan, H., Cui, L., Tang, B. L., Holst, Jens Juul, Fledelius, C., Johansen, P. B., Jelicks, L. A., Serup, P., Nishimura, E. & Charron, M. J., 2003, In: Proc Natl Sci. 100, p. 1438-1443

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Lower glucose-dependent insulinotropic polypeptide (GIP) response but similar glucagon-like peptide 1 (GLP-1), glycaemic, and insulinaemic response to ancient wheat compared to modern wheat depends on processing

    Bakhøj, S., Flint, A., Holst, Jens Juul & Tetens, Inge , 2003, In: European Journal of Clinical Nutrition. 57, 10, p. 1254-1261 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Meals with similar energy densities but rich in protein, fat, carbohydrate, or alcohol have different effects on energy expenditure and substrate metabolism but not on appetite and energy intake

    Raben, A. B., Agerholm-Larsen, L., Flint, A., Holst, Jens Juul & Astrup, A., 2003, In: American Journal of Clinical Nutrition. 77, 1, p. 91-100 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    NO has tonic inhibitory, but is not involved in the vagal control or VIP effects on motility of the porcine antrum

    Schmidt, P. T., Ørskov, C., Rasmussen, T. N. & Holst, Jens Juul, 2003, In: Scandinavian Journal of Gastroenterology. 38, p. 955-961

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Neutral endopeptidase 24.11 and dipeptidyl peptidase IV are both involved in regulating the metabolic stability of glucagon-like peptide-1 in vivo.

    Plamboeck, A., Holst, Jens Juul, Carr, R. D. & Deacon, Carolyn F., 2003, In: Advances in Experimental Medicine and Biology. 524, p. 303-12 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    No effect of physiological concentrations of glucagon-like peptide-2 on appetite and energy intake in normal weight subjects

    Sørensen, L. B., Flint, A., Raben, A. B., Hartmann, B., Holst, Jens Juul & Astrup, A., 2003, In: International Journal of Obesity. 27, 4, p. 450-456 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    No reactive hypoglycaemia after subcutaneous administrations of GLP-1 in lean type 2 diabetic patients and in patients with diabeties secondary to chronic pancreatitis

    Knop, F., Vilsbøll, T., Larsen, S., Holst, Jens Juul & Krarup, T., 2003, In: Diabetes Care. 26, p. 2581-2587

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Normalisation of glucose concentrations and deceleration of gastric emptying of solid meals during intravenous glucagon-like peptide-1 (GLP-1) in patients with type 2 diabetes

    Meier, J. J., Gallwitz, B., Salmen, S., Goetze, O., Holst, Jens Juul & Schmidt, W. E., 2003, In: J. Clin. Endocrinol. Metab.. 88, p. 2719-2725

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Peripheral administration of GLP-2 to humans has no effect on gastric emptying or satiety

    Schmidt, P. T., Näslund, E., Grybäck, P., Jacobsson, H., Hartmann, B., Holst, Jens Juul & Hellström, P. M., 2003, In: Regul. Pept.. 116, p. 21-25

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    Prediction of glycemic index in mixed meals

    Møller, B. K., Flint, A., Pedersen, D., Raben, A. B., Tetens, I., Holst, Jens Juul & Astrup, A., 2003. 1 p.

    Research output: Contribution to conferencePaperResearch

  62. Published

    Role of luminal nutrients and endogenous GLP-2 in intestinal adaptation to mid small bowel resection

    Dahly, E. M., Gillingham, M. B., Guo, Z., Murali, S. G., Nelson, D. W., Holst, Jens Juul & Ney, D. M., 2003, In: Amer. J. Physiol.. 284, p. G670-G682

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    Similar elimination rates of GLP-1 in obese type 2 diabetic patients and matched healthy subjects

    Vilsbøll, T., Krarup, T., Agersø, H. & Holst, Jens Juul, 2003, In: J. Clin. Endocrinol. Metab.. 88, p. 220-224

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published

    Similar insulin secretory response to a gastric inhibitory polypeptide bolus injection at euglycemia in first-degree relatives of patients with type 2 diabetes and control subjects.

    Meier, J. J., Nauck, M. A., Siepmann, N., Greulich, M., Holst, Jens Juul, Deacon, Carolyn F., Schmidt, W. E. & Gallwitz, B., 2003, In: Metabolism - Clinical and Experimental. 52, 12, p. 1579-85 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    Small intestinal dysfunction accompanies the complex endocrinopathy of human proprotein convertase 1 deficiency

    Jackson, R. S., Creemers, J. W. M., Saraf Faraoqi, I., Raffin-Sanson, M. L., Varro, A., Dockray, G. J., Holst, J. J., Brubaker, P. L., Corvol, P., Polonsky, K. S., Ostrega, D., Becker, K. L., Bertagna, X., Hutton, J. C., White, A., Dattani, M. T., Hussain, K., Middleton, S. J., Nicholl, T. M., Lindley, K. J. & 1 others, O Rahlly, S., 2003, In: J. Clin. Invest.. 112, p. 1550-1560

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. Published

    Somatostatin receptors.

    Møller, L. N., Stidsen, C. E., Hartmann, B. & Holst, Jens Juul, 2003, In: BBA General Subjects. 1616, 1, p. 1-84 83 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Published

    Structural differences between rye and wheat bread but not total fiber content may explain the lower postprandial insulin response to rye bread

    Juntunen, K. S., Laaksonen, D. E., Aitio, K., Niskanen, L. K., Holst, Jens Juul, Savolainen, K. E., Liukkonen, K. H., Poutanen, K. S. & Mykkänen, H. M., 2003, In: Am. J. Clin. Nutr.. 78, p. 957-964

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    The influence of GLP-1 on glucose-induced insulin secretion: effect on ß-cells sensitivity in type 2 and non-diabetic subjects

    Kjems, L. L., Holst, Jens Juul, Vølund, A. A. & Madsbad, S., 2003, In: Diabetes. 52, p. 380-386

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    The pathogenesis of diabetes involves a defective amplication of the late phase insulin response to glucose by GIP - regardless of aetiology and phenotype

    Vilsbøll, T., Knop, F., Krarup, T., Johansen, A., Madsbad, S., Larsen, S., Hansen, T., Pedersen, O. & Holst, Jens Juul, 2003, In: J. Clin. Endocrinol. Metab.. 88, p. 4897-4903

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    The reduction in hepatic insulin clearance after oral glucose is not mediated by gastric inhibitory polypeptide (GIP).

    Meier, J. J., Gallwitz, B., Siepmann, N., Holst, Jens Juul, Deacon, Carolyn F., Schmidt, W. E. & Nauck, M. A., 2003, In: Regulatory Peptides. 113, 1-3, p. 95-100 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. Published

    Will GLP-1 treatment increase blood pressure? Summary and comment

    Holst, Jens Juul, 2003, In: Diabetes Monitor. 15, p. 15-17

    Research output: Contribution to journalJournal articleResearchpeer-review

  72. 2002
  73. Published

    The effects of duodenal peptides on glucagon-like peptide-1 secretion from the ileum. A duodeno--ileal loop?

    Hansen, L. & Holst, Jens Juul, 31 Dec 2002, In: Regulatory Peptides. 110, 1, p. 39-45 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published

    Repaglinide at a cellular level

    Krogsgaard Thomsen, M., Bokvist, K., Høy, M., Buschard, K., Holst, Jens Juul, Lindström, P. & Gromada, J., Dec 2002, In: Diabetes, nutrition & metabolism. 15, 6 Suppl, p. 15-8 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    Anti-diabetogenic effect of the human amylin analogue, pramlintide, in Type 1 diabetes is not mediated by GLP-1

    Ahrén, B., Adner, N., Svartberg, J., Petrella, E., Holst, Jens Juul & Gutniak, M. K., Sep 2002, In: Diabetic Medicine. 19, 9, p. 790-2 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. Published

    Disruption of PC1/3 expression in mice causes dwarfism and multiple neuroendocrine peptide processing defects

    Zhu, X., Zhou, A., Dey, A., Norrbom, C., Carroll, R., Zhang, C., Laurent, V., Lindberg, I., Ugleholdt, Randi Kjærsgaard, Holst, Jens Juul & Steiner, D. F., 6 Aug 2002, In: Proceedings of the National Academy of Sciences of the United States of America. 99, 16, p. 10293-8 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Published

    Circulating levels of ghrelin and GLP-1 are inversely related during glucose ingestion

    Djurhuus, C. B., Hansen, T. K., Gravholt, C., Ørskov, L., Hosoda, H., Kangawa, K., Jørgensen, J. O. L., Holst, Jens Juul & Schmitz, O., Jul 2002, In: Hormone and Metabolic Research. Supplement. 34, 7, p. 411-3 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  78. Published

    Feast or famine - are GLP-1 and ghrelin secretion intertwined?

    Djurhuus, C. B., Hansen, T. K., Holst, Jens Juul & Schmitz, O., Jul 2002, In: Hormone and Metabolic Research. Supplement. 34, 7, p. 353-4 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. Published

    Long-term inhibition of dipeptidyl peptidase IV improves glucose tolerance and preserves islet function in mice

    Reimer, M. K., Holst, Jens Juul & Ahrén, B., May 2002, In: European Journal of Endocrinology. Supplement. 146, 5, p. 717-27 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  80. Published

    Short-term administration of glucagon-like peptide-2. Effects on bone mineral density and markers of bone turnover in short-bowel patients with no colon

    Haderslev, Kent Valentin, Jeppesen, Palle Bekker, Hartmann, Bolette, Thulesen, J., Sorensen, H. A., Graff, J., Tofteng, F., Poulsen, S. S., Madsen, J. L., Holst, Jens Juul, Staun, Michael, Mortensen, P. B. & Poulsen, Steen Seier, 1 Apr 2002, In: Scandinavian Journal of Gastroenterology. 37, 4, p. 392-8 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. Published

    Abnormal release of incretins and cortisol after oral glucose in subjects with insulin-resistant myotonic dystrophy

    Johansson, A., Olsson, T., Cederquist, K., Forsberg, H., Holst, Jens Juul, Seckl, J. R. & Ahren, B., Mar 2002, In: European Journal of Endocrinology. Supplement. 146, 3, p. 397-405 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. Published

    Effects of glucagon-like peptide 1 on counterregulatory hormone responses, cognitive functions, and insulin secretion during hyperinsulinemic, stepped hypoglycemic clamp experiments in healthy volunteers

    Nauck, M. A., Heimesaat, M. M., Behle, K., Holst, Jens Juul, Nauck, M. S., Ritzel, R., Hüfner, M. & Schmiegel, W. H., Mar 2002, In: The Journal of clinical endocrinology and metabolism. 87, 3, p. 1239-46 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Published

    Effects of topical ropivacaine on eicosanoids and neurotransmitters in the rectum of patients with distal ulcerative colitis

    Hillingsø, Jens Georg, Kjeldsen, J., Schmidt, P. T., Rasmussen, T. N., Fisher-Hansen, B., Holst, Jens Juul, Lauristen, K., Bukhave, K. & Rask-Madsen, J., Mar 2002, In: Scandinavian Journal of Gastroenterology. 37, 3, p. 325-9 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. Published

    Preservation of active incretin hormones by inhibition of dipeptidyl peptidase IV suppresses meal-induced incretin secretion in dogs

    Deacon, Carolyn F., Wamberg, S., Bie, P., Hughes, T. E. & Holst, Jens Juul, Feb 2002, In: Journal of Endocrinology. 172, 2, p. 355-62 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. Published

    Abnormal release of incretins and cortisol after oral glucose in insulin resistant myotonic dystrophy

    Johansson, Å., Olsson, T., Cederquist, K., Forsberg, H., Holst, Jens Juul, Seckl, J. R. & Ahrén, B., 2002, In: European Journal of Endocrinology. 146, p. 397-405

    Research output: Contribution to journalJournal articleResearchpeer-review

  86. Published

    Case report: Somatostatin producing teratoma, causing rapidly alternating extreme hyperglycemia and hypoglycemia, and ovarian somatostatinoma

    Gregersen, G., Holst, Jens Juul, Trankjaer, A., Stadil, F. & Mogensen, A. M., 2002, In: Metabolism. 51, 9, p. 1180-1183 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. Published

    Dipeptidyl peptidase IV inhibition as an approach to the treatment and prevention of type 2 diabetes: a historical perspective.

    Deacon, Carolyn F. & Holst, Jens Juul, 2002, In: Biochemical and Biophysical Research Communications. 294, 1, p. 1-4 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Published

    Early differential defects of insulin secretion and action in 19-year-old caucasian men who had low birth weight.

    Jensen, C. B., Storgaard, H., Dela, Flemming, Holst, Jens Juul, Madsbad, Sten & Vaag, Allan, 2002, In: Diabetes. 51, 4, p. 1271-80 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Published

    Effect of 6-week course of glucagon-like peptide 1 on glycaemic control, insulin sensitivity, and beta-cell function in type 2 diabetes: a parallel-group study.

    Olsen, Ane Mette Zander, Madsbad, Sten, Madsen, J. L. & Holst, Jens Juul, 2002, In: Lancet. 359, 9309, p. 824-30 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Published

    Effects of glucagon-like peptide-1 (GLP-1) on counterregulatory hormone responses, cognitive functions and insulin secretion during hyperinsulinaemic, stepped hypoglycaemic clamp experiments in healthy volunteers

    Nauck, M. A., Heimesaat, M. M., Behle, K., Holst, Jens Juul, Nauck, M. S., Hüfner, M. & Schmiegel, W. H., 2002, In: J. Clin. Endocrinol. Metab.. 87, p. 1239-1246

    Research output: Contribution to journalJournal articleResearchpeer-review

  91. Published

    Et nyopdaget fotopigment i retina, melanopsin, styrer hjernens biologiske ur.

    Hannibal, J., Fahrenkrug, J. & Holst, Jens Juul, 2002, In: Ugeskrift for læger. 164, 19, p. 2523

    Research output: Contribution to journalJournal articleResearchpeer-review

  92. Published

    Fedtvaevet og insulin-resistens: resistin og adiponectin.

    Holst, Jens Juul & Binderup, M., 2002, In: Ugeskrift for læger. 164, 16, p. 2173-6 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. Published

    GLP-1 and GLP-2 act in concert to inhibit fasted, but not fed, small bowel motility in the rat.

    Bozkurt, A., Näslund, E., Holst, Jens Juul & Hellström, P. M., 2002, In: Regulatory Peptides. 107, 1-3, p. 129-35 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. Published

    GLP-1-(9-36) amide reduces blood glucose in anesthetized pigs by a mechanism that does not involve insulin secretion.

    Deacon, Carolyn F., Plamboeck, A., Møller, Søren & Holst, Jens Juul, 2002, In: American Journal of Physiology: Endocrinology and Metabolism. 282, 4, p. E873-9

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    Gastric inhibitory polypeptide analogues: do they have a therapeutic role in diabetes mellitus similar to that of glucagon-like Peptide-1?

    Holst, Jens Juul, 2002, In: BioDrugs. 16, 3, p. 175-81 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  96. Published

    Gliclazide directly inhibits arginine-induced glucagon release.

    Cejvan, K., Coy, D. H., Holst, Jens Juul, Cerasi, E. & Efendic, S., 2002, In: Diabetes. 51 Suppl 3, p. S381-4

    Research output: Contribution to journalJournal articleResearchpeer-review

  97. Published

    Immunoneutralization of endogenous glucagon-like peptide-2 reduces adaptive intestinal growth in diabetic rats.

    Hartmann, B., Thulesen, J., Hare, K. J., Kissow, Hannelouise, Orskov, C., Poulsen, Steen Seier & Holst, Jens Juul, 2002, In: Regulatory Peptides. 105, 3, p. 173-9 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  98. Published

    Inhibition of gastric inhibitory polypeptide signaling prevents obesity.

    Miyawaki, K., Yamada, Y., Ban, N., Ihara, Y., Tsukiyama, K., Zhou, H., Fujimoto, S., Oku, A., Tsuda, K., Toyokuni, S., Hiai, H., Mizunoya, W., Fushiki, T., Holst, J. J., Makino, M., Tashita, A., Kobara, Y., Tsubamoto, Y., Jinnouchi, T., Jomori, T. & 1 others, Seino, Y., 2002, In: Nature Medicine. 8, 7, p. 738-42 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. Published

    Long-term inhibition of dipeptidyl peptidase IV improves glucose tolerance and preserves islet function in mice

    Reimer, M. K., Holst, Jens Juul & Ahrén, B., 2002, In: European Journal of Endocrinology. 146, p. 717-727

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Published

    Postprandial glucose, insulin and incretin responses to grain products in healthy subjects

    Juntunen, K. S., Lioukkonen, H. K., Poutanen, S. K., Niskanen, K. L., Holst, Jens Juul & Mykkänen, M. H., 2002, In: Am. J. Clin. Nutr.. 75, p. 254-262

    Research output: Contribution to journalJournal articleResearchpeer-review

  101. Published

    Preservation of active Effects of topical ropivacaine om eicosanoids and neurotransmitters in the rectum of patients with distal ulcerative colitis

    Hillingsøe, J. G., Kjeldsen, J., Schmidt, P. T., Rasmussen, T. N., Arlander, E., Fischer-Hansen, B., Holst, Jens Juul, Lauritsen, K., Bukhave, K. & Rask-Madsen, J., 2002, In: Scandinavian Journal of Gastroenterology. 37, p. 325-329

    Research output: Contribution to journalJournal articleResearchpeer-review

  102. Published

    Short-term administration of Glucagon-like peptide-2. Effects on bone mass density and markers of bone remodelling in short bowel patients with no colon

    Haderslev, K. V., Jeppesen, P. B., Hartmann, B., Thulesen, J., Sørensen, H. A., Graff, J., Hansen, B. S., Tofteng, F., Poulsen, Steen Seier, Madsen, J. L., Holst, Jens Juul, Staun, M. & Mortensen, P. B., 2002, In: Scandinavian Journal of Gastroenterology. vol. 37, p. 392-398

    Research output: Contribution to journalJournal articleResearchpeer-review

  103. Published

    The truncated metabolite GLP-2 (3-33) interacts with the GLP-2 receptor as a partial agonist.

    Thulesen, J., Knudsen, L. B., Hartmann, B., Hastrup, S., Kissow, Hannelouise, Jeppesen, P. B., Ørskov, Cathrine, Holst, Jens Juul & Poulsen, Steen Seier, 2002, In: Regulatory Peptides. 103, 1, p. 9-15 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 4207