Jonas Thue Treebak

Jonas Thue Treebak

Associate Professor


  1. Published

    Impaired insulin-induced site-specific phosphorylation of TBC1 domain family, member 4 (TBC1D4) in skeletal muscle of type 2 diabetes patients is restored by endurance exercise-training

    Vind, B. F., Pehmøller, C., Treebak, Jonas Thue, Birk, Jesper Bratz, Hey-Mogensen, M., Beck-Nielsen, H., Zierath, J. R., Wojtaszewski, Jørgen F P & Højlund, K., 2011, In: Diabetologia. 54, 1, p. 157-167 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Impaired insulin-stimulated phosphorylation of Akt and AS160 in skeletal muscle of women with polycystic ovary syndrome is reversed by pioglitazone treatment

    Højlund, K., Glintborg, D., Andersen, Nicoline Resen, Birk, Jesper Bratz, Treebak, Jonas Thue, Frøsig, C., Beck-Nielsen, H. & Wojtaszewski, Jørgen F P, 2008, In: Diabetes. 57, 2, p. 357-366 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. E-pub ahead of print

    Impaired skeletal muscle regeneration in diabetes: From cellular and molecular mechanisms to novel treatments

    Espino Gonzalez, Ever, Dalbram, E., Mounier, R., Gondin, J., Farup, J., Jessen, N. & Treebak, Jonas Thue, 7 Mar 2024, (E-pub ahead of print) In: Cell Metabolism.

    Research output: Contribution to journalReviewResearchpeer-review

  4. Published

    Impairments in site-specific AS160 phosphorylation and effects of exercise training

    Consitt, L. A., Van Meter, J., Newton, C. A., Collier, D. N., Dar, M. S., Wojtaszewski, Jørgen F P, Treebak, Jonas Thue, Tanner, C. J. & Houmard, J. A., 2013, In: Diabetes. 62, 10, p. 3437-3447 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Insulin resistance after a 72-h fast is associated with impaired AS160 phosphorylation and accumulation of lipid and glycogen in human skeletal muscle

    Vendelbo, M., Clasen, B. F. F., Treebak, Jonas Thue, Møller, L., Krusenstjerna-Hafstrøm, T., Madsen, M., Nielsen, Thomas Svava, Stødkilde-Jørgensen, H., Pedersen, S. B., Jørgensen, J. O. L., Goodyear, L. J., Wojtaszewski, Jørgen F P, Møller, N. & Jessen, N., 2012, In: American Journal of Physiology: Endocrinology and Metabolism. 302, 2, p. E190-E200 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Insulin stimulation regulates AS160 and TBC1D1 phosphorylation sites in human skeletal muscle

    Middelbeek, R. J. W., Chambers, M. A., Tantiwong, P., Treebak, Jonas Thue, An, D., Hirshman, M. F., Musi, N. & Goodyear, L. J., Jun 2013, In: Nutrition and Diabetes. 3, 74, p. e74

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Intravenous nicotinamide riboside elevates mouse skeletal muscle NAD+ without impacting respiratory capacity or insulin sensitivity

    Damgaard, Mads Vargas, Nielsen, Thomas Svava, Basse, A. L., Chubanava, Sabina, Trost, K., Moritz, Thomas, Dellinger, R. W., Larsen, Steen & Treebak, Jonas Thue, 2022, In: iScience. 25, 2, 21 p., 103863.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Investigation of the specificity and mechanism of action of the ULK1/AMPK inhibitor SBI-0206965

    Ahwazi, Danial, Neopane, K., Markby, G. R., Kopietz, F., Ovens, A. J., Dall, M., Hassing, Anna Skab, Gräsle, P., Alshuweishi, Y., Treebak, Jonas Thue, Salt, I. P., Göransson, O., Zeqiraj, E., Scott, J. W. & Sakamoto, Kei, 2021, In: Biochemical Journal. 478, 15, p. 2977-2997 21 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Lack of AMPKalpha2 enhances pyruvate dehydrogenase activity during exercise

    Klein, D. K., Pilegaard, Henriette, Treebak, Jonas Thue, Jensen, Thomas Elbenhardt, Viollet, B., Schjerling, Peter & Wojtaszewski, Jørgen F P, 2007, In: American Journal of Physiology: Endocrinology and Metabolism. 293, 5, p. E1242-E1249 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Lipolysis drives expression of the constitutively active receptor GPR3 to induce adipose thermogenesis

    Sveidahl Johansen, O., Ma, T., Hansen, J. B., Markussen, L. K., Schreiber, R., Reverte-Salisa, L., Dong, H., Christensen, D. P., Sun, W., Gnad, T., Karavaeva, I., Nielsen, T. S., Kooijman, S., Cero, C., Dmytriyeva, O., Shen, Y., Razzoli, M., O'Brien, S. L., Kuipers, E. N., Nielsen, C. H. & 31 others, Orchard, W., Willemsen, N., Jespersen, N. Z., Lundh, M., Sustarsic, E. G., Hallgren, C. M., Frost, M., McGonigle, S., Isidor, Marie Sophie, Broholm, C., Pedersen, Oluf Borbye, Hansen, Jacob B., Grarup, Niels, Hansen, Torben, Kjær, Andreas, Granneman, J. G., Babu, M. M., Calebiro, D., Nielsen, S., Rydén, M., Soccio, R., Rensen, P. C. N., Treebak, Jonas Thue, Schwartz, Thue W., Emanuelli, Brice, Bartolomucci, A., Pfeifer, A., Zechner, R., Schéele, Camilla Charlotte Nielsen, Mandrup, S. & Gerhart-Hines, Z., 2021, In: Cell. 184, 13, p. 3502-3518 + 50 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Lysates of Methylococcus capsulatus Bath induce a lean-like microbiota, intestinal FoxP3+RORγt+IL-17+ Tregs and improve metabolism

    Jensen, B. A. H., Holm, J. B., Larsen, I. S., von Burg, N., Derer, S., Sonne, S. B., Pærregaard, S. I., Damgaard, M. V., Indrelid, S. A., Rivollier, A., Agrinier, A. L., Sulek, K., Arnoldussen, Y. J., Fjære, E., Marette, A., Angell, I. L., Rudi, K., Treebak, J. T., Madsen, L., Åkesson, C. P. & 5 others, Agace, W., Sina, C., Kleiveland, C. R., Kristiansen, Karsten & Lea, T. E., 2021, In: Nature Communications. 12, 19 p., 1093.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Macronutrient composition in the diets.

    Sonne, Si Brask, Treebak, Jonas Thue, Pilegaard, Henriette, Fjare, E., Froyland, L., Kristiansen, Karsten, Hao, Q., Madsen, L., Petersen, R. K., Ngo, H. T., Lillefosse, H. H., Liaset, B., Ringholm, S. & Ma, Tao, 2011

    Research output: Other contributionResearch

  13. Published

    Mass-spectrometry-based proteomics reveals mitochondrial supercomplexome plasticity

    Gonzalez-Franquesa, A., Stocks, Ben Nicholas, Chubanava, Sabina, Hattel, H. B., Moreno Justicia, Roger, Peijs, Lone, Treebak, Jonas Thue, Zierath, Juleen R & Deshmukh, Atul Shahaji, 2021, In: Cell Reports. 35, 8, 20 p., 109180.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Metabolic plasticity and obesity-associated changes in diurnal postexercise metabolism in mice

    Pendergrast, L. A., Ashcroft, Stephen Paul, Ehrlich, Amy M, Treebak, Jonas Thue, Krook, A., Dollet, L. & Zierath, Juleen R, 2024, In: Metabolism: Clinical and Experimental. 155, 12 p., 155834.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    MicroRNAs in non-alcoholic fatty liver disease: Progress and perspectives

    Hochreuter, Mette Yde, Dall, M., Treebak, Jonas Thue & Barrès, Romain, 2022, In: Molecular Metabolism. 65, 17 p., 101581.

    Research output: Contribution to journalReviewResearchpeer-review

  16. Published

    Mitochondrial function in liver cells is resistant to perturbations in NAD+ salvage capacity

    Dall, M., Trammell, Sam, Asping, M., Hassing, Anna Skab, Agerholm, M., Vienberg, S. G., Gillum, M. P., Larsen, Steen & Treebak, Jonas Thue, 2019, In: The Journal of Biological Chemistry. 294, 36, p. 13304-13326 23 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Molecular mechanism by which AMP-activated protein kinase activation promotes glycogen accumulation in muscle

    Hunter, R. W., Treebak, Jonas Thue, Wojtaszewski, Jørgen F P & Sakamoto, Kei, 2011, In: Diabetes. 60, 3, p. 766-774 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    NAD+ and NAFLD - Caution, Causality, and Careful Optimism

    Dall, M., Hassing, Anna Skab & Treebak, Jonas Thue, 2022, In: The Journal of Physiology. 600, 5, p. 1135-1154

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    NAMPT-dependent NAD+ biosynthesis controls circadian metabolism in a tissue-specific manner

    Basse, A. L., Nielsen, K. N., Karavaeva, Iuliia, Ingerslev, L. R., Ma, Tao, Havelund, J. F., Nielsen, Thomas Svava, Frost, M., Peics, J., Kellezi, Emilie Dalbram, Dall, M., Zierath, Juleen R, Barrès, Romain, Færgeman, N. J., Treebak, Jonas Thue & Gerhart-Hines, Zach, 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 14, e2220102120.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    NAMPT-mediated NAD+ biosynthesis is indispensable for adipose tissue plasticity and development of obesity

    Nielsen, K. N., Peics, J., Ma, Tao, Karavaeva, Iuliia, Dall, M., Chubanava, Sabina, Basse, A. L., Dmytriyeva, O., Treebak, Jonas Thue & Gerhart-Hines, Zach, May 2018, In: Molecular Metabolism. 11, p. 178-188 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Nicotinamide riboside does not alter mitochondrial respiration, content or morphology in skeletal muscle from obese and insulin resistant men

    Dollerup, O. L., Chubanava, Sabina, Agerholm, M., Søndergård, S. D., Altıntaş, Ali, Møller, A. B., Høyer, K. F., Ringgaard, S., Stødkilde-Jørgensen, H., Lavery, G. G., Barrès, Romain, Larsen, Steen, Prats Gavalda, Clara, Jessen, N. & Treebak, Jonas Thue, 2020, In: Journal of Physiology. 598, 4, p. 731-754

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Oral supplementation of nicotinamide riboside alters intestinal microbial composition in rats and mice, but not humans

    Peluso, A. A., Lundgaard, A. T., Babaei, P., Mousovich-Neto, F., Rocha, A. L., Damgaard, M. V., Bak, E. G., Gnanasekaran, T., Dollerup, O. L., Trammell, S. A. J., Nielsen, T. S., Kern, T., Abild, C. B., Sulek, K., Ma, T., Gerhart-Hines, Z., Gillum, M. P., Arumugam, M., Ørskov, C., McCloskey, D. & 4 others, Jessen, N., Herrgård, M. J., Mori, M. A. S. & Treebak, Jonas Thue, 2023, In: npj Aging. 9, 21 p., 7.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    PICK1-Deficient Mice Maintain Their Glucose Tolerance During Diet-Induced Obesity

    Backe, M. B., Andersen, Rita Chan, Jensen, M., Jin, C., Hundahl, C., Dmytriyeva, O., Treebak, Jonas Thue, Hansen, J. B., Gerhart-Hines, Zach, Madsen, Kenneth Lindegaard & Holst, Birgitte, 2023, In: Journal of the endocrine society. 7, 6, p. 1-13 bvad057.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Perturbations in the p53/miR-34a/SIRT1 pathway in the R6/2 Huntington's disease model

    Reynolds, R. H., Petersen, M. H., Willert, C. W., Heinrich, M., Nymann, N., Dall, M., Treebak, Jonas Thue, Björkqvist, M., Silahtaroglu, Asli, Hasholt, Lis Frydenreich & Nørremølle, Anne, 2018, In: Molecular and Cellular Neuroscience. 88, p. 118-129

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Perturbations of NAD+ salvage systems impact mitochondrial function and energy homeostasis in mouse myoblasts and intact skeletal muscle

    Andersen, M. A., Dall, M., Jensen, Benjamin Anderschou Holbech, Prats Gavalda, Clara, Madsen, S., Basse, A. L., Graae, A., Risis, S., Goldenbaum, J., Quistorff, B., Larsen, Steen, Vienberg, S. G. & Treebak, Jonas Thue, 2018, In: American Journal of Physiology: Endocrinology and Metabolism. 314, 4, p. E377-E395 19 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 7974