Mani Arumugam

Mani Arumugam


  1. 2014
  2. Published

    Interplay between FGF21 and insulin action in the liver regulates metabolism

    Emanuelli, Brice, Vienberg, S. G., Smyth, G., Cheng, C., Stanford, K. I., Arumugam, Mani, Michael, M. D., Adams, A. C., Kharitonenkov, A. & Kahn, C. R., 3 Feb 2014, In: The Journal of Clinical Investigation. 124, 2, p. 515-27 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    An integrated catalog of reference genes in the human gut microbiome

    Li, J., Jia, H., Cai, X., Zhong, H., Feng, Q., Sunagawa, S., Arumugam, M., Kultima, J. R., Prifti, E., Nielsen, T., Juncker, A., Manichanh, C., Chen, B., Zhang, W., Levenez, F., Wang, J., Xu, X., Xiao, L., Liang, S., Zhang, D. & 17 others, Zhang, Z., Chen, W., Zhao, H., Al-Aama, J. Y., Edris, S., Yang, H., Wang, J., Hansen, Torben, Nielsen, H. B., Brunak, S., Kristiansen, Karsten, Guarner, F., Pedersen, Oluf Borbye, Doré, J., Ehrlich, S. D., Bork, P. & Wang, J., 2014, In: Nature Biotechnology. 32, 8, p. 834-845 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Identification and assembly of genomes and genetic elements in complex metagenomic samples without using reference genomes

    Nielsen, H. B., Almeida, M., Juncker, A., Rasmussen, S., Li, J., Sunagawa, S., Plichta, D. R., Gautier, L., Pedersen, A. G., Le Chatelier, E., Pelletier, E., Bonde, I., Nielsen, T., Manichanh, C., Arumugam, M., Batto, J-M., dos Santos, M. B. Q., Blom, N., Borruel, N., Burgdorf, K. S. & 31 others, Boumezbeur, F., Casellas, F., Doré, J., Dworzynski, P., Guarner, F., Hansen, Torben, Hildebrand, F., Kaas, R. S., Kennedy, S., Kristiansen, Karsten, Kultima, J. R., Léonard, P., Levenez, F., Lund, O., Moumen, B., Le Paslier, D., Pons, N., Pedersen, Oluf Borbye, Prifti, E., Qin, J., Raes, J., Sørensen, Søren Johannes, Tap, J., Tims, S., Ussery, D., Yamada, T., Renault, P., Sicheritz-Pontén, T., Bork, P., Wang, J. & MetaHIT Consortium, M. C., 2014, In: Nature Biotechnology. 32, 8, p. 822–828 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. 2013
  6. Published

    Country-specific antibiotic use practices impact the human gut resistome

    Forslund, K., Sunagawa, S., Kultima, J. R., Mende, D. R., Arumugam, Mani, Typas, A. & Bork, P., Jul 2013, In: Genome Research. 23, 7, p. 1163-9 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Consistent mutational paths predict eukaryotic thermostability

    van Noort, V., Bradatsch, B., Arumugam, Mani, Amlacher, S., Bange, G., Creevey, C., Falk, S., Mende, D. R., Sinning, I., Hurt, E. & Bork, P., 2013, In: B M C Evolutionary Biology. 13, p. 7

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Genomic variation landscape of the human gut microbiome

    Schloissnig, S., Arumugam, Mani, Sunagawa, S., Mitreva, M., Tap, J., Zhu, A., Waller, A., Mende, D. R., Kultima, J. R., Martin, J., Kota, K., Sunyaev, S. R., Weinstock, G. M. & Bork, P., 2013, In: Nature. 493, 7430, p. 45-50 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Metagenomic species profiling using universal phylogenetic marker genes

    Sunagawa, S., Mende, D. R., Zeller, G., Izquierdo-Carrasco, F., Berger, S. A., Kultima, J. R., Coelho, L. P., Arumugam, M., Tap, J., Nielsen, H. B., Rasmussen, S., Brunak, S., Pedersen, O. B., Guarner, F., de Vos, W. M., Wang, J., Li, J., Doré, J., Ehrlich, S. D., Stamatakis, A. & 1 others, Bork, P., 2013, In: Nature Methods. 10, 12, p. 1196-1199 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Richness of human gut microbiome correlates with metabolic markers

    Le Chatelier, E., Nielsen, T., Qin, J., Prifti, E., Hildebrand, F., Falony, G., Almeida, M., Arumugam, M., Batto, J-M., Kennedy, S., Leonard, P., Li, J., Burgdorf, K. S., Grarup, N., Jørgensen, T., Brandslund, I., Nielsen, H. B., Juncker, A., dos Santos, M. B. Q., Levenez, F. & 62 others, Pons, N., Rasmussen, Simon, Sunagawa, S., Tap, J., Tims, S., Zoetendal, E. G., Brunak, S., Clément, K., Doré, J., Kleerebezem, M., Kristiansen, Karsten, Renault, P., Sicheritz-Ponten, T., de Vos, W. M., Zucker, J., Raes, J., Hansen, Torben, Bork, P., Wang, J., Ehrlich, S. D., Pedersen, Oluf Borbye, Guedon, E., Delorme, C., Layec, S., Khaci, G., van de Guchte, M., Vandemeulebrouck, G., Jamet, A., Dervyn, R., Sanchez, N., Maguin, E., Haimet, F., Winogradski, Y., Cultrone, A., Leclerc, M., Juste, C., Blottière, H., Pelletier, E., LePaslier, D., Artiguenave, F., Bruls, T., Weissenbach, J., Turner, K., Parkhill, J., Antolin, M., Manichanh, C., Casellas, F., Boruel, N., Varela, E., Torrejon, A., Guarner, F., Denariaz, G., Derrien, M., van Hylckama Vlieg, J. E. T., Veiga, P., Oozeer, R., Knol, J., Rescigno, M., Brechot, C., Mérieux, A., M'Rini, C. & Yamada, T., 2013, In: Nature. 500, 7464, p. 541-546 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. 2012
  12. Published

    Assessment of metagenomic assembly using simulated next generation sequencing data

    Mende, D. R., Waller, A. S., Sunagawa, S., Järvelin, A. I., Chan, M. M., Arumugam, Mani, Raes, J. & Bork, P., 2012, In: P L o S One. 7, 2, p. e31386

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. MOCAT: a metagenomics assembly and gene prediction toolkit

    Kultima, J. R., Sunagawa, S., Li, J., Chen, W., Chen, H., Mende, D. R., Arumugam, Mani, Pan, Q., Liu, B., Qin, J., Wang, J. & Bork, P., 2012, In: PLOS ONE. 7, 10, p. e47656

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    The human small intestinal microbiota is driven by rapid uptake and conversion of simple carbohydrates

    Zoetendal, E. G., Raes, J., van den Bogert, B., Arumugam, Mani, Booijink, C. C. G. M., Troost, F. J., Bork, P., Wels, M., de Vos, W. M. & Kleerebezem, M., 2012, In: I S M E Journal. 6, 7, p. 1415-26 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. 2011
  16. Published

    Enterotypes of the human gut microbiome: [Plus]Corrigendum [Plus]Addendum

    Arumugam, M., Raes, J., Pelletier, E., Le Paslier, D., Yamada, T., Mende, D. R., Fernandes, G. R., Tap, J., Bruls, T., Batto, J-M., dos Santos, M. B. Q., Borruel, N., Casellas, F., Fernandez, L., Gautier, L., Hansen, T., Hattori, M., Hayashi, T., Kleerebezem, M., Kurokawa, K. & 31 others, Leclerc, M., Levenez, F., Manichanh, C., Nielsen, H. B., Nielsen, T., Pons, N., Poulain, J., Qin, J., Sicheritz-Ponten, T., Tims, S., Torrents, D., Ugarte, E., Zoetendal, E. G., Wang, J., Guarner, F., Pedersen, Oluf Borbye, de Vos, W. M., Brunak, Søren, Doré, J., Antolín, M., Artiguenave, F., Blottiere, H. M., Almeida, M., Brechot, C., Cara, C., Chervaux, C., Cultrone, A., Delorme, C., Denariaz, G., Kristiansen, Karsten & MetaHIT Consortium, M. C., 2011, In: Nature. 473, 7346, p. 174-180 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Insight into structure and assembly of the nuclear pore complex by utilizing the genome of a eukaryotic thermophile

    Amlacher, S., Sarges, P., Flemming, D., van Noort, V., Kunze, R., Devos, D. P., Arumugam, Mani, Bork, P. & Hurt, E., 2011, In: Cell. 146, 2, p. 277-89 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Minimum information about a marker gene sequence (MIMARKS) and minimum information about any (x) sequence (MIxS) specifications

    Yilmaz, P., Kottmann, R., Field, D., Knight, R., Cole, J. R., Amaral-Zettler, L., Gilbert, J. A., Karsch-Mizrachi, I., Johnston, A., Cochrane, G., Vaughan, R., Hunter, C., Park, J., Morrison, N., Rocca-Serra, P., Sterk, P., Arumugam, M., Bailey, M., Baumgartner, L., Birren, B. W. & 78 others, Blaser, M. J., Bonazzi, V., Booth, T., Bork, P., Bushman, F. D., Buttigieg, P. L., Chain, P. S. G., Charlson, E., Costello, E. K., Huot-Creasy, H., Dawyndt, P., DeSantis, T., Fierer, N., Fuhrman, J. A., Gallery, R. E., Gevers, D., Gibbs, R. A., San Gil, I., Gonzalez, A., Gordon, J. I., Guralnick, R., Hankeln, W., Highlander, S., Hugenholtz, P., Jansson, J., Kau, A. L., Kelley, S. T., Kennedy, J., Knights, D., Koren, O., Kuczynski, J., Kyrpides, N., Larsen, R., Lauber, C. L., Legg, T., Ley, R. E., Lozupone, C. A., Ludwig, W., Lyons, D., Maguire, E., Methé, B. A., Meyer, F., Muegge, B., Nakielny, S., Nelson, K. E., Nemergut, D., Neufeld, J. D., Newbold, L. K., Oliver, A. E., Pace, N. R., Palanisamy, G., Peplies, J., Petrosino, J., Proctor, L., Pruesse, E., Quast, C., Raes, J., Ratnasingham, S., Ravel, J., Relman, D. A., Assunta-Sansone, S., Schloss, P. D., Schriml, L., Sinha, R., Smith, M. I., Sodergren, E., Spo, A., Stombaugh, J., Tiedje, J. M., Ward, D. V., Weinstock, G. M., Wendel, D., White, O., Whiteley, A., Wilke, A., Wortman, J. R., Yatsunenko, T. & Glöckner, F. O., 2011, In: Nature Biotechnology. 29, 5, p. 415-20 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. 2010
  20. Published

    SmashCell: A software framework for the analysis of single-cell amplified genome sequences.

    Harrington, E. D., Arumugam, Mani, Raes, J., Bork, P. & Relman, D. A., Oct 2010, In: Bioinformatics. 26, 23, p. 2979-2980 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    SmashCommunity: A metagenomic annotation and analysis tool.

    Arumugam, Mani, Harrington, E. D., Foerstner, K. U., Raes, J. & Bork, P., Oct 2010, In: Bioinformatics. 26, 23, p. 2977-2978 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    A human gut microbial gene catalogue established by metagenomic sequencing

    MetaHIT Consortium, M. C., 2010, In: Nature. 464, 7285, p. 59-65 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. 2009
  24. Published

    Transcriptome complexity in a genome-reduced bacterium.

    Güell, M., van Noort, V., Yus, E., Chen, W., Leigh-Bell, J., Michalodimitrakis, K., Yamada, T., Arumugam, Mani, Doerks, T., Kühner, S., Rode, M., Suyama, M., Schmidt, S., Gavin, A., Bork, P. & Serrano, L., Nov 2009, In: Science. 326, 5957, p. 1268-1271 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Pairagon: a highly accurate, HMM-based cDNA-to-genome aligner.

    Lu, D. V., Brown, R. H., Arumugam, Mani & Brent, M. R., Jul 2009, In: Bioinformatics. 25, 13, p. 1587-1593 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. 2007
  27. Published

    The Treeterbi and Parallel Treeterbi algorithms: efficient, optimal decoding for ordinary, generalized and pair HMMs.

    Keibler, E., Arumugam, Mani & Brent, M. R., Mar 2007, In: Bioinformatics. 23, 5, p. 545-554 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. 2006
  29. Published

    Molecular properties of adult mouse gastric and intestinal epithelial progenitors in their niches

    Giannakis, M., Stappenbeck, T. S., Mills, J. C., Leip, D. G., Lovett, M., Clifton, S. W., Ippolito, J. E., Glasscock, J. I., Arumugam, Mani, Brent, M. R. & Gordon, J. I., 2006, In: Journal of Biological Chemistry. 281, 16, p. 11292-300 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Pairagon+N-SCAN_EST: a model-based gene annotation pipeline

    Arumugam, Mani, Wei, C., Brown, R. H. & Brent, M. R., 2006, In: Genome Biology (Online Edition). 7 Suppl 1, p. S5.1-10

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. 2005
  32. Published

    Closing in on the C. elegans ORFeome by cloning TWINSCAN predictions

    Wei, C., Lamesch, P., Arumugam, Mani, Rosenberg, J., Hu, P., Vidal, M. & Brent, M. R., 2005, In: Genome Research. 15, 4, p. 577-82 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. 2004
  34. Published

    EMPRR: A high-dimensional EM-based piecewise regression algorithm

    Arumugam, Mani & Scott, S. D., 2004, Proceedings of the 2004 International Conference on Machine Learning and Applications, ICMLA '04. Kantardzic, M., Nasraoui, O. & Milanova, M. (eds.). p. 264-271 8 p. (Proceedings of the 2004 International Conference on Machine Learning and Applications, ICMLA '04).

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

  35. Published

    Genome sequence of the Brown Norway rat yields insights into mammalian evolution

    Gibbs, R. A., Weinstock, G. M., Metzker, M. L., Muzny, D. M., Sodergren, E. J., Scherer, S., Scott, G., Steffen, D., Worley, K. C., Burch, P. E., Okwuonu, G., Hines, S., Lewis, L., DeRamo, C., Delgado, O., Dugan-Rocha, S., Miner, G., Morgan, M., Hawes, A., Gill, R. & 31 others, Celera, Holt, R. A., Adams, M. D., Amanatides, P. G., Baden-Tillson, H., Barnstead, M., Chin, S., Evans, C. A., Ferriera, S., Fosler, C., Glodek, A., Gu, Z., Jennings, D., Kraft, C. L., Nguyen, T., Pfannkoch, C. M., Sitter, C., Sutton, G. G., Venter, J. C., Woodage, T., Smith, D., Lee, H., Gustafson, E., Cahill, P., Kana, A., Doucette-Stamm, L., Weinstock, K., Fechtel, K., Weiss, R. B., Arumugam, Mani & Rat Genome Sequencing Project Consortium, R. G. S. P. C., 2004, In: Nature. 428, 6982, p. 493-521 29 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Identification of rat genes by TWINSCAN gene prediction, RT-PCR, and direct sequencing

    Wu, J. Q., Shteynberg, D., Arumugam, Mani, Gibbs, R. A. & Brent, M. R., 2004, In: Genome Research. 14, 4, p. 665-71 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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