Brice Emanuelli
Associate Professor
Emanuelli Group
Blegdamsvej 3B, Mærsk Tårnet, 7. sal
2200 København N.
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Intrinsic differences in adipocyte precursor cells from different white fat depots
Macotela, Y., Emanuelli, Brice, Mori, M. A., Gesta, S., Schulz, T. J., Tseng, Y. & Kahn, C. R., Jul 2012, In: Diabetes. 61, 7, p. 1691-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cross-talk between insulin and Wnt signaling in preadipocytes: role of Wnt co-receptor low density lipoprotein receptor-related protein-5 (LRP5)
Palsgaard, J., Emanuelli, Brice, Winnay, J. N., Sumara, G., Karsenty, G. & Kahn, C. R., 6 Apr 2012, In: The Journal of Biological Chemistry. 287, 15, p. 12016-26 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
Cross-talk between insulin and Wnt signaling in preadipocytes. ROLE OF Wnt CO-RECEPTOR LDL RECEPTOR-RELATED PROTEIN-5 (LRP5)
Palsgaard, J., Emanuelli, Brice, Winnay, J. N., Sumara, G., Karsenty, G. & Kahn, C. R., 5 Aug 2016, In: The Journal of Biological Chemistry. 291, 32, p. 16878Research output: Contribution to journal › Comment/debate › Research › peer-review
Insulin Induces Suppressor of Cytokine Signaling-3 Tyrosine Phosphorylation through Janus-activated Kinase
Peraldi, P., Filloux, C., Emanuelli, Brice, Hilton, D. J. & Van Obberghen, E., 6 Jul 2001, In: Journal of Biological Chemistry. 276, 27, p. 24614-24620 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Calsyntenin 3β Is Dynamically Regulated by Temperature in Murine Brown Adipose and Marks Human Multilocular Fat
Plucinska, Kaja, Jespersen, N. Z., Brown, E. L., Petersen, P. S., Rupar, K., Nielsen, S., Schéele, Camilla Charlotte Nielsen & Emanuelli, Brice, 2020, In: Frontiers in Endocrinology. 11, 7 p., 579785.Research output: Contribution to journal › Journal article › Research › peer-review
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Distinct signalling properties of insulin receptor substrate (IRS)-1 and IRS-2 in mediating insulin/IGF-1 action
Rabiee, A., Krüger, M., Ardenkjær-Larsen, J., Ronald Kahn, C. & Emanuelli, Brice, 2018, In: Cellular Signalling. 47, p. 1-15Research output: Contribution to journal › Journal article › Research › peer-review
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White adipose remodeling during browning in mice involves YBX1 to drive thermogenic commitment
Rabiee, A., Plucinska, Kaja, Isidor, Marie Sophie, Brown, E. L., Tozzi, M., Sidoli, S., Petersen, P. S. S., Agueda Oyarzabal, Marina, Torsetnes, S. B., Chehabi, G. N., Lundh, M., Altıntaş, Ali, Barrès, Romain, Jensen, O. N., Gerhart-Hines, Zach & Emanuelli, Brice, 2021, In: Molecular Metabolism. 44, 17 p., 101137.Research output: Contribution to journal › Journal article › Research › peer-review
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Full activation of thermogenesis in brown adipocytes requires Basigin action
Rupar, K., Isidor, Marie Sophie, Argemi Muntadas, Lidia, Agueda Oyarzabal, Marina, Plucinska, Kaja, Brown, E. L., Mattanovich, M., Bossi, Simone, Tozzi, M., Tandio, David, Petersen, P. S. S., Henriksen, T. I., Trošt, K., Hansen, Jacob B., Gerhart-Hines, Zach, Nielsen, S., Moritz, Thomas & Emanuelli, Brice, 2023, In: F E B S Journal. 290, 10, p. 2673-2691Research output: Contribution to journal › Journal article › Research › peer-review
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FGF6 and FGF9 regulate UCP1 expression independent of brown adipogenesis
Shamsi, F., Xue, R., Huang, T. L., Lundh, M., Liu, Y., Leiria, L. O., Lynes, M. D., Kempf, E., Wang, C. H., Sugimoto, S., Nigro, P., Landgraf, K., Schulz, T., Li, Y., Emanuelli, B., Kothakota, S., Williams, L. T., Jessen, N., Pedersen, S. B., Böttcher, Y. & 6 others, , 2020, In: Nature Communications. 11, 1, 16 p., 1421.Research output: Contribution to journal › Journal article › Research › peer-review
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Cardiolipin Synthesis in Brown and Beige Fat Mitochondria Is Essential for Systemic Energy Homeostasis
Sustarsic, E. G., Ma, T., Lynes, M. D., Larsen, M., Karavaeva, I., Havelund, J. F., Nielsen, C. H., Jedrychowski, M. P., Moreno-Torres, M., Lundh, M., Plucinska, K., Jespersen, N. Z., Grevengoed, T. J., Kramar, B., Peics, J., Hansen, J. B., Shamsi, F., Forss, I., Neess, D., Keipert, S. & 24 others, , 2018, In: Cell Metabolism. 28, 1, p. 159-174.e11Research output: Contribution to journal › Journal article › Research › peer-review
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Lipolysis drives expression of the constitutively active receptor GPR3 to induce adipose thermogenesis
Sveidahl Johansen, O., Ma, T., Hansen, J. B., Markussen, L. K., Schreiber, R., Reverte-Salisa, L., Dong, H., Christensen, D. P., Sun, W., Gnad, T., Karavaeva, I., Nielsen, T. S., Kooijman, S., Cero, C., Dmytriyeva, O., Shen, Y., Razzoli, M., O'Brien, S. L., Kuipers, E. N., Nielsen, C. H. & 31 others, , 2021, In: Cell. 184, 13, p. 3502-3518 + 50 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Critical nodes in signalling pathways: insights into insulin action
Taniguchi, C. M., Emanuelli, Brice & Kahn, C. R., Feb 2006, In: Nature Reviews. Molecular Cell Biology. 7, 2, p. 85-96 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Dynamic interplay between Afadin S1795 phosphorylation and diet regulates glucose homeostasis in obese mice
Tozzi, M., Brown, E. L., Petersen, P. S., Lundh, M., Isidor, Marie Sophie, Plucinska, Kaja, Nielsen, Thomas Svava, Agueda Oyarzabal, Marina, Small, Lewin Barkla, Treebak, Jonas Thue & Emanuelli, Brice, 2022, In: The Journal of Physiology. 600, 4, p. 885-902Research output: Contribution to journal › Journal article › Research › peer-review
Surfing the insulin signaling web
Van Obberghen, E., Baron, V., Delahaye, L., Emanuelli, Brice, Filippa, N., Giorgetti-Peraldi, S., Lebrun, P., Mothe-Satney, I., Peraldi, P., Rocchi, S., Sawka-Verhelle, D., Tartare-Deckert, S. & Giudicelli, J., 1 Dec 2001, In: European Journal of Clinical Investigation. 31, 11, p. 966-977 12 p.Research output: Contribution to journal › Review › Research › peer-review
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Adipose-specific deletion of TFAM increases mitochondrial oxidation and protects mice against obesity and insulin resistance
Vernochet, C., Mourier, A., Bezy, O., Macotela, Y., Boucher, J., Rardin, M. J., An, D., Lee, K. Y., Ilkayeva, O. R., Zingaretti, C. M., Emanuelli, Brice, Smyth, G., Cinti, S., Newgard, C. B., Gibson, B. W., Larsson, N. & Kahn, C. R., 5 Dec 2012, In: Cell Metabolism. 16, 6, p. 765-76 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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CRISPR-engineered human brown-like adipocytes prevent diet-induced obesity and ameliorate metabolic syndrome in mice
Wang, C., Lundh, M., Fu, A., Kriszt, R., Huang, T. L., Lynes, M. D., Leiria, L. O., Shamsi, F., Darcy, J., Greenwood, B. P., Narain, N. R., Tolstikov, V., Smith, K. L., Emanuelli, Brice, Chang, Y., Hagen, S., Danial, N. N., Kiebish, M. A. & Tseng, Y., 2020, In: Science Translational Medicine. 12, 558, 15 p., eaaz8664.Research output: Contribution to journal › Journal article › Research › peer-review
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The brominated flame retardant PBDE 99 promotes adipogenesis via regulating mitotic clonal expansion and PPARγ expression
Wen, Q., Xie, X., Zhao, C., Ren, Q., Zhang, X., Wei, D., Emanuelli, Brice & Du, Y., 2019, In: The Science of the Total Environment. 670, p. 67-77 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Cross talk between insulin and bone morphogenetic protein signaling systems in brown adipogenesis
Zhang, H., Schulz, T. J., Espinoza, D. O., Huang, T. L., Emanuelli, Brice, Kristiansen, Karsten & Tseng, Y., 1 Sep 2010, In: Molecular and Cellular Biology. 30, 17, p. 4224-33 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Fasting- and ghrelin-induced food intake is regulated by NAMPT in the hypothalamus
de Guia, R. M., Hassing, Anna Skab, Skov, Louise Julie, Ratner, C., Plucinska, Kaja, Madsen, S., Diep, T. A., dela Cruz, Gelo, Trammell, Sam, Sustarsic, E. G., Emanuelli, Brice, Gillum, M. P., Gerhart-Hines, Zach, Holst, Birgitte & Treebak, Jonas Thue, 2020, In: Acta Physiologica. 228, 4Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ablation of Nampt in AgRP neurons leads to neurodegeneration and impairs fasting- and ghrelin-mediated food intake
de Guia, R. M., Hassing, Anna Skab, Ma, Tao, Plucinska, Kaja, Holst, Birgitte, Gerhart-Hines, Zach, Emanuelli, Brice & Treebak, Jonas Thue, 2021, In: F A S E B Journal. 35, 5, e21450.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 41852944
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Cardiolipin Synthesis in Brown and Beige Fat Mitochondria Is Essential for Systemic Energy Homeostasis
Research output: Contribution to journal › Journal article › Research › peer-review
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265
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Bidirectional manipulation of gene expression in adipocytes using CRISPRa and siRNA
Research output: Contribution to journal › Journal article › Research › peer-review
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119
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Calsyntenin 3β Is Dynamically Regulated by Temperature in Murine Brown Adipose and Marks Human Multilocular Fat
Research output: Contribution to journal › Journal article › Research › peer-review
Published