Tune H Pers
Associate Professor - Promotion Programme
Pers Group
Blegdamsvej 3B, Mærsk Tårnet, 8. sal, 2200 København N.
- 2019
- Published
Multiple sclerosis genomic map implicates peripheral immune cells and microglia in susceptibility
Patsopoulos, N. A., Baranzini, S. E., Santaniello, A., Shoostari, P., Cotsapas, C., Wong, G., Beecham, A. H., James, T., Replogle, J., Vlachos, I. S., McCabe, C., Pers, T. H., Brandes, A., White, C., Keenan, B., Cimpean, M., Winn, P., Panteliadis, I. P., Robbins, A., Andlauer, T. F. M. & 32 others, , 2019, In: Science. 365, 6460, eaav7188.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PAIRUP-MS: Pathway analysis and imputation to relate unknowns in profiles from mass spectrometry-based metabolite data
Hsu, Y. H., Churchhouse, C., Pers, Tune H, Mercader, J. M., Metspalu, A., Fischer, K., Fortney, K., Morgen, E. K., Gonzalez, C., Gonzalez, M. E., Esko, T. & Hirschhorn, J. N., 2019, In: PLOS Computational Biology. 15, 1, 26 p., e1006734.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Population-based identity-by-descent mapping combined with exome sequencing to detect rare risk variants for schizophrenia
Harold, D., Connolly, S., Riley, B. P., Kendler, K. S., McCarthy, S. E., McCombie, W. R., Richards, A., Owen, M. J., O'Donovan, M. C., Walters, J., Donnelly, P., Bates, L., Barroso, I., Blackwell, J. M., Bramon, E., Brown, M. A., Casas, J. P., Corvin, A., Deloukas, P., Duncanson, A. & 32 others, , 2019, In: American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics. 180, 3, p. 223-231 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Production of stellate cells from induced pluripotent stem cells to study Alzheimer's disease pathology
Mogus, L., Bergmann, T. B., Liu, Y., Lee, J., Pfisterer, U. G., Handfield, L., Asenjo Martinez, A., Seemann, Ernst Stefan, Witter, M., Khodosevich, Konstantin, Gorodkin, Jan, Hemberg, M., Pers, Tune H & Hall, Vanessa Jane, 2019. 1 p.Research output: Contribution to conference › Conference abstract for conference › Communication
- Published
Protein-coding variants implicate novel genes related to lipid homeostasis contributing to body-fat distribution
Justice, A. E., Karaderi, T., Highland, H. M., Young, K. L., Graff, M., Lu, Y., Turcot, V., Auer, P. L., Fine, R. S., Guo, X., Schurmann, C., Lempradl, A., Marouli, E., Mahajan, A., Winkler, T. W., Locke, A. E., Medina-Gomez, C., Esko, T., Vedantam, S., Giri, A. & 31 others, , 2019, In: Nature Genetics. 51, 3, p. 452-469 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantitative proteomics and single-nucleus transcriptomics of the sinus node elucidates the foundation of cardiac pacemaking
Linscheid, N., Logantha, S. J. R. J., Poulsen, C., Zhang, S., Schrölkamp, Maren, Egerod, Kristoffer Lihme, Thompson, J. J., Kitmitto, A., Galli, G., Humphries, M. J., Zhang, H., Pers, Tune H, Olsen, Jesper Velgaard, Boyett, M. & Lundby, Alicia, 2019, In: Nature Communications. 10, 19 p., 2889.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
RhoA in tyrosine hydroxylase neurons regulates food intake and body weight via altered sensitivity to peripheral hormones
Skov, Louise Julie, Ratner, C., Hansen, Nikolaj Winther, Thompson, J. J., Egerod, Kristoffer Lihme, Burm, Hayley Beth, Dalbøge, L. S., Hedegaard, M. A., Brakebusch, Cord Herbert, Pers, Tune H, Perrier, Jean-Francois Marie & Holst, Birgitte, 2019, In: Journal of Neuroendocrinology. 31, 7, 13 p., UNSP e12761.Research output: Contribution to journal › Conference article › Research › peer-review
- Published
Sandwich cortial lamination and single-cell analysis decodes the developing spatial processing system
Liu, Y., Bergmann, T. B., Lee, J., Pfisterer, U. G., Handfield, L-F., Mori, Y., Asenjo Martinez, A., Lisa Vargas, I., Seemann, E. S., Lee, J. T. H., Patikis, N., Peralvo Vidal, J. M., Pihl, M., Kornum, B. R., Thomsen, P. D., Hyttel, P., Witter, M., Khodosevich, K., Gorodkin, J., Hemberg, M. & 2 others, , 2019. 45 p.Research output: Contribution to conference › Paper › Communication
- Published
The developing Entorhinal Cortex – a cellular map
Bergmann, T. B., Liu, Y., Lee, J., Pfisterer, U. G., Asenjo Martinez, A., Seemann, Ernst Stefan, Pihl, M., Thomsen, Preben Dybdahl, Hyttel, P., witter, M., Khodosevich, Konstantin, Gorodkin, Jan, Pers, Tune H & Hall, Vanessa Jane, 2019.Research output: Contribution to conference › Conference abstract for conference › Research
- Published
Tracing the origin of adult intestinal stem cells
Guiu, J., Hannezo, E., Yui, S., Demharter, S., Ulyanchenko, Svetlana, Maimets, Martti, Jørgensen, A., Perlman, S., Lundvall, L., Mamsen, L. S., Larsen, A., Olesen, R. H., Andersen, C. Y., Thuesen, L. L., Hare, Kristine Juul, Pers, Tune H, Khodosevich, Konstantin, Simons, B. D. & Jensen, Kim Bak, 2019, In: Nature. 570, 7759, p. 107-111Research output: Contribution to journal › Letter › Research › peer-review
- Published
Uncovering the anatomical and molecular landscape of the starting point of Alzheimer’s disease in the brain
Bergmann, T. B., Liu, Y., Lee, J., Pfisterer, U. G., Asenjo Martinez, A., Seemann, Ernst Stefan, Pihl, M., Thomsen, Preben Dybdahl, Hyttel, P., witter, M., Khodosevich, Konstantin, Gorodkin, Jan, Pers, Tune H & Hall, Vanessa Jane, 2019.Research output: Contribution to conference › Conference abstract for conference › Research
- 2018
- Published
Genome Analyses of >200,000 Individuals Identify 58 Loci for Chronic Inflammation and Highlight Pathways that Link Inflammation and Complex Disorders
Ligthart, S., Vaez, A., Vosa, U., Stathopoulou, M. G., de Vries, P. S., Prins, B. P., Van der Most, P. J., Tanaka, T., Naderi, E., Rose, L. M., Wu, Y., Karlsson, R., Barbalic, M., Lin, H., Pool, R., Zhu, G., Mace, A., Sidore, C., Trompet, S., Mangino, M. & 266 others, , 1 Nov 2018, In: American Journal of Human Genetics. 103, 5, p. 691-706Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes
Bipolar Disorder and Schizophrenia Working Group of the Psychiatric Genomics Consortium douglas.ruderfer@vanderbilt.edu, B. D. A. S. W. G. O. T. P. G. C. D. R. E., Psychosis Endophenotypes International Consortium, P. E. I. C. & Wellcome Trust Case-Control Consortium, W. T. C. C., 14 Jun 2018, In: Cell. 173, 7, p. 1705-1715.e16Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes
Bonàs-Guarch, S., Guindo-Martínez, M., Miguel-Escalada, I., Grarup, N., Sebastian, D., Rodriguez-Fos, E., Sánchez, F., Planas-Fèlix, M., Cortes-Sánchez, P., González, S., Timshel, P., Pers, T. H., Morgan, C. C., Moran, I., Atla, G., González, J. R., Puiggros, M., Martí, J., Andersson, E. A., Díaz, C. & 23 others, , 22 Jan 2018, In: Nature Communications. 9, 14 p., 321.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity
Turcot, V., Lu, Y., Highland, H. M., Bang, L. E., Benn, M., Kamstrup, P. R., Bork-Jensen, J., Frikke-Schmidt, R., Gjesing, A. P., Grarup, N., Hansen, T., Have, C. T., Jørgensen, T., Nielsen, S. F., Linneberg, A. R., Pedersen, O., Pers, T. H., Vestergaard, H., Nordestgaard, B., Tybjærg-Hansen, A. & 15 others, , 1 Jan 2018, In: Nature Genetics. 50, p. 26-41 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Age at first birth in women is genetically associated with increased risk of schizophrenia
Ni, G., Gratten, J., Wray, N. R., Lee, S. H., Ripke, S., Neale, B. M., Corvin, A., Walters, J. T. R., Farh, K. H., Holmans, P. A., Lee, P., Bulik-Sullivan, B., Collier, D. A., Huang, H., Pers, T. H., Agartz, I., Agerbo, E., Albus, M., Alexander, M., Amin, F. & 281 others, , 2018, In: Scientific Reports. 8, 1, p. 1-14 10168.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals
Lee, J. J., Wedow, R., Okbay, A., Kong, E., Maghzian, O., Zacher, M., Tuan Anh Nguyen-Viet, Bowers, P., Sidorenko, J., Linner, R. K., Fontana, M. A., Kundu, T., Lee, C., Li, H., Li, R., Royer, R., Timshel, P. N., Walters, R. K., Willoughby, E. A., Yengo, L. & 58 others, , 2018, In: Nature Genetics. 50, 8, p. 1112-+Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome-wide association analyses identify 39 new susceptibility loci for diverticular disease
Maguire, L. H., Handelman, S. K., Du, X., Chen, Y., Pers, Tune H & Speliotes, E. K., 2018, In: Nature Genetics. 50, 10, p. 1359-1365Research output: Contribution to journal › Letter › Research › peer-review
- Published
Molecular genetic overlap between migraine and major depressive disorder
Yang, Y., Zhao, H., Boomsma, D. I., Ligthart, L., Belin, A. C., Smith, G. D., Esko, T., Freilinger, T. M., Hansen, T. F., Ikram, M. A., Kallela, M., Kubisch, C., Paraskevi, C., Strachan, D. P., Wessman, M., Gormley, P., Anttila, V., Winsvold, B. S., Palta, P., Esko, T. & 30 others, , 2018, In: European Journal of Human Genetics. 26, 8, p. 1202-1216 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The developmental neurogenic niche of the Entorhinal cortex revealed by single-cell transcriptomics.
Bergmann, T. B., Liu, Y., Lee, J., Peralvo Vidal, Juan Miguel, Mori, Yuki, Seemann, Ernst Stefan, Pihl, M., Thomsen, Preben Dybdahl, Hyttel, P., witter, M., Gorodkin, Jan, Hall, Vanessa Jane & Pers, Tune H, 2018.Research output: Contribution to conference › Conference abstract for conference › Research
- Published
Uncovering the anatomical and molecular landscape of the developing entorhinal cortex.
Liu, Y., Bergmann, T. B., Peralvo Vidal, Juan Miguel, Lee, J., Mori, Yuki, Seemann, Ernst Stefan, Pihl, M., Thomsen, Preben Dybdahl, Gorodkin, Jan, Hyttel, P., Pers, Tune H, witter, M. & Hall, Vanessa Jane, 2018.Research output: Contribution to conference › Conference abstract for conference › Research
- 2017
- Published
A Low-Frequency Inactivating Akt2 Variant Enriched in the Finnish Population is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk
Manning, A., Highland, H. M., Gasser, J., Sim, X., Tukiainen, T., Fontanillas, P., Grarup, N., Rivas, M. A., Mahajan, A., Locke, A. E., Cingolani, P., Pers, T. H., Viñuela, A., Brown, A. A., Wu, Y., Flannick, J., Fuchsberger, C., Gamazon, E. R., Gaulton, K. J., Im, H. K. & 243 others, , Dec 2017, In: Diabetes. 66, p. 2019-2032 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A molecular census of arcuate hypothalamus and median eminence cell types
Campbell, J. N., Macosko, E. Z., Fenselau, H., Pers, Tune H, Lyubetskaya, A., Tenen, D., Goldman, M., Verstegen, A. M. J., Resch, J. M., McCarroll, S. A., Rosen, E. D., Lowell, B. B. & Tsai, L. T., Mar 2017, In: Nature Neuroscience. 20, 3, p. 484-496 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rare and low-frequency coding variants alter human adult height
Marouli, E., Graff, M., Medina-Gomez, C., Lo, K. S., Wood, A. R., Kjaer, T. R., Fine, R. S., Lu, Y., Schurmann, C., Highland, H. M., Rüeger, S., Thorleifsson, G., Justice, A. E., Lamparter, D., Stirrups, K. E., Turcot, V., Young, K. L., Winkler, T. W., Esko, T., Karaderi, T. & 31 others, , 9 Feb 2017, In: Nature. 542, 7640, p. 186-190 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An Expanded Genome-Wide Association Study of Type 2 Diabetes in Europeans
Scott, R. A., Scott, L. J., Mägi, R., Marullo, L., Gaulton, K. J., Kaakinen, M., Pervjakova, N., Pers, T. H., Johnson, A. D., Eicher, J. D., Jackson, A. U., Ferreira, T., Lee, Y., Ma, C., Steinthorsdottir, V., Thorleifsson, G., Qi, L., Van Zuydam, N. R., Mahajan, A., Chen, H. & 155 others, , 2017, In: Diabetes. 66, 11, p. 2888-2902Research output: Contribution to journal › Journal article › Research › peer-review
ID: 19412078
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464
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52 Genetic Loci Influencing Myocardial Mass
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
377
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Quantitative proteomics and single-nucleus transcriptomics of the sinus node elucidates the foundation of cardiac pacemaking
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
181
downloads
Re-analysis of public genetic data reveals a rare X-chromosomal variant associated with type 2 diabetes
Research output: Contribution to journal › Journal article › Research › peer-review
Published