Endocrine Regulation of Metabolism in the Juul Holst Group

The overarching aim of the group is to understand the functional challenges of obesity and type 2 diabetes and to provide new principles for improved therapies. The group is conducting state of the art research in the field of translational physiology and has excelled in developing experimental models and assays resulting in identification and development of drugs based on the hormones GLP-1, GLP-2 and GIP.

Professor Jens Juul Holst in his lab with a CBMR researcher

 

 

 

 

 

 

 

Our primary research area is the physiology of peptide hormones and neurotransmitters, particularly those related to pancreatic and gastrointestinal functions and signaling.

The group has excelled in developing experimental models and assays enabling us to measure the secretion and actions of metabolically active gut and pancreatic peptide hormones . Our analyses are founded on immunological and mass spectrometry-based approaches, and the implementation of both single cell approaches, isolated perfused organs, in vivo animal studies, and notably, extensive human studies. Group leader prof. Juul Holst explains; “We strive to translate our experimental work into effective clinical studies in order to understand the functional challenges of obesity and diabetes, and to provide new principles for improved therapies”.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Group leader Jens Juul Holst

Group Leader

Jens Juul Holst
Professor
MD, Dr. med. Sci. 

Phone +45 2875 7518
jjholst@sund.ku.dk

Group members

Name Title Job responsibilities Phone E-mail
Andersen, Daniel Bjørklund PhD Student Juul Holst Group, Endocrine Regulation of Metabolism +4535337499 E-mail
Constantini, Tabatha Emilia de A External Juul Holst Group, Endocrine Regulation of Metabolism   E-mail
Holst, Jens Juul Professor Group Leader, Juul Holst Group, Endocrine Regulation of Metabolism +4528757518 E-mail
Lehmann, Jule Helen Glaser Academic Officer Juul Holst Group, Endocrine Regulation of Metabolism +4591855193 E-mail