Current and Emerging Treatment Options in Diabetes Care
Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Current and Emerging Treatment Options in Diabetes Care. / Clemmensen, Christoffer; Müller, Timo D; Finan, Brian; Tschöp, Matthias H; DiMarchi, Richard.
Metabolic Control. Vol. 233 Springer, 2016. p. 437-459 (Handbook of Experimental Pharmacology; No. 233).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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TY - CHAP
T1 - Current and Emerging Treatment Options in Diabetes Care
AU - Clemmensen, Christoffer
AU - Müller, Timo D
AU - Finan, Brian
AU - Tschöp, Matthias H
AU - DiMarchi, Richard
PY - 2016
Y1 - 2016
N2 - Diabetes constitutes an increasing threat to human health, particularly in newly industrialized and densely populated countries. Type 1 and type 2 diabetes arise from different etiologies but lead to similar metabolic derangements constituted by an absolute or relative lack of insulin that results in elevated plasma glucose. In the last three decades, a set of new medicines built upon a deeper understanding of physiology and diabetic pathology have emerged to enhance the clinical management of the disease and related disorders. Recent insights into insulin-dependent and insulin-independent molecular events have accelerated the generation of a series of novel medicinal agents, which hold the promise for further advances in the management of diabetes. In this chapter, we provide a historical context for what has been accomplished to provide perspective for future research and novel emerging treatment options.
AB - Diabetes constitutes an increasing threat to human health, particularly in newly industrialized and densely populated countries. Type 1 and type 2 diabetes arise from different etiologies but lead to similar metabolic derangements constituted by an absolute or relative lack of insulin that results in elevated plasma glucose. In the last three decades, a set of new medicines built upon a deeper understanding of physiology and diabetic pathology have emerged to enhance the clinical management of the disease and related disorders. Recent insights into insulin-dependent and insulin-independent molecular events have accelerated the generation of a series of novel medicinal agents, which hold the promise for further advances in the management of diabetes. In this chapter, we provide a historical context for what has been accomplished to provide perspective for future research and novel emerging treatment options.
KW - Anti-Obesity Agents
KW - Bariatric Surgery
KW - Diabetes Mellitus
KW - Fibroblast Growth Factors
KW - Glucose
KW - Humans
KW - Hypoglycemic Agents
KW - Leptin
KW - Pancreas Transplantation
KW - Journal Article
KW - Review
U2 - 10.1007/164_2015_7
DO - 10.1007/164_2015_7
M3 - Book chapter
C2 - 25903416
SN - 978-3-319-29804-7
VL - 233
T3 - Handbook of Experimental Pharmacology
SP - 437
EP - 459
BT - Metabolic Control
PB - Springer
ER -
ID: 199074987