Association of Walnut Consumption with Total and Cause-Specific Mortality and Life Expectancy in U.S. Adults
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Association of Walnut Consumption with Total and Cause-Specific Mortality and Life Expectancy in U.S. Adults. / Liu, Xiaoran; Guasch-Ferré, Marta; Tobias, Deirdre K; Li, Yanping.
In: Nutrients, Vol. 13, No. 8, 2021.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Association of Walnut Consumption with Total and Cause-Specific Mortality and Life Expectancy in U.S. Adults
AU - Liu, Xiaoran
AU - Guasch-Ferré, Marta
AU - Tobias, Deirdre K
AU - Li, Yanping
PY - 2021
Y1 - 2021
N2 - Walnut consumption is associated with health benefits. We aimed to (1) examine the association between walnut consumption and mortality and (2) estimate life expectancy in relation to walnut consumption in U.S. adults. We included 67,014 women of the Nurses' Health Study (1998-2018) and 26,326 men of the Health Professionals Follow-up Study (1998-2018) who were free of cancer, heart disease, and stroke at baseline. We used Cox regression models to estimate hazard ratios (HRs) and 95% confidence intervals (CIs). During up to 20 years of follow-up, we documented 30,263 deaths. The hazard ratios for total mortality across categories of walnut intake (servings/week), as compared to non-consumers, were 0.95 (95% confidence interval (CI), 0.91, 0.98) for <1 serving/week, 0.94 (95% CI, 0.89, 0.99) for 1 serving/week, 0.87 (95% CI, 0.82, 0.93) for 2-4 servings/week, and 0.86 (95% CI, 0.79, 0.93) for >=5 servings/week (p for trend <0.0001). A greater life expectancy at age 60 (1.30 years in women and 1.26 years in men) was observed among those who consumed walnuts more than 5 servings/week compared to non-consumers. Higher walnut consumption was associated with a lower risk of total and CVD mortality and a greater gained life expectancy among U.S. elder adults.
AB - Walnut consumption is associated with health benefits. We aimed to (1) examine the association between walnut consumption and mortality and (2) estimate life expectancy in relation to walnut consumption in U.S. adults. We included 67,014 women of the Nurses' Health Study (1998-2018) and 26,326 men of the Health Professionals Follow-up Study (1998-2018) who were free of cancer, heart disease, and stroke at baseline. We used Cox regression models to estimate hazard ratios (HRs) and 95% confidence intervals (CIs). During up to 20 years of follow-up, we documented 30,263 deaths. The hazard ratios for total mortality across categories of walnut intake (servings/week), as compared to non-consumers, were 0.95 (95% confidence interval (CI), 0.91, 0.98) for <1 serving/week, 0.94 (95% CI, 0.89, 0.99) for 1 serving/week, 0.87 (95% CI, 0.82, 0.93) for 2-4 servings/week, and 0.86 (95% CI, 0.79, 0.93) for >=5 servings/week (p for trend <0.0001). A greater life expectancy at age 60 (1.30 years in women and 1.26 years in men) was observed among those who consumed walnuts more than 5 servings/week compared to non-consumers. Higher walnut consumption was associated with a lower risk of total and CVD mortality and a greater gained life expectancy among U.S. elder adults.
KW - Adult
KW - Aged
KW - Cardiovascular Diseases/mortality
KW - Cause of Death
KW - Diet/methods
KW - Female
KW - Follow-Up Studies
KW - Humans
KW - Juglans
KW - Life Expectancy/trends
KW - Male
KW - Middle Aged
KW - Mortality/trends
KW - Nuts
KW - Proportional Hazards Models
KW - Regression Analysis
KW - United States
U2 - 10.3390/nu13082699
DO - 10.3390/nu13082699
M3 - Journal article
C2 - 34444859
VL - 13
JO - Nutrients
JF - Nutrients
SN - 2072-6643
IS - 8
ER -
ID: 351039179